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INDONESIA
Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 314 Documents
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STUDI LITERATUR : RASIONALITAS PENGGUNAAN ANTIPSIKOTIK PADA PASIEN GANGGUAN KEJIWAAN SKIZOFRENIA Adin Hakim Kurniawan; Yetri Elisya; Muhamad Irfan
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.556

Abstract

People with severe mental disorders are people with acute psychotics and schizophrenia. Schizophrenia is a severe mental disorder, characterized by many disturbances in thinking, affecting language, perception, and a sense of self-awareness. Drug rationality is the use of rational drugs where patients receive treatment that corresponding clinical needs. The results of Basic Health Research in 2013 and 2018 showed an increase in the prevalence of ODGJ of 5.3%. The main purpose of this research to To find out the rationality antipsychotic use in schizophrenic psychiatric patients. Thisresearch design used was a literaturestudy, articles were collected using the GoogleSchoolar database. The results showed that there werepatients who have schizophrenia are men with an age range of 18-45 yearswith a Antipsychotic classification. Typical.Classification single therapeutic classusing haloperidol and combination therapy class using chlorpromazine and Haloperidol.as well as having good rationality based on the right indication, the right medicine, the right patient, the right dose.
OPTIMASI KOMBINASI HPMC DAN CARBOPOL DALAM FORMULA SEDIAAN GEL HAND SANITIZER EKSTRAK ETANOL BIJI PEPAYA (Carica papaya L.) SERTA UJI AKTIVITAS ANTIBAKTERI TERHADAP Escherichia coli Christe Mareta Ardika Sari; Disa Andriani; Didik Wahyudi
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.563

Abstract

Papaya seeds (Carica papaya L.) have antibacterial activity because they contain terpenoid, karpain and flavonoid compounds. Flavonoids have OH groups that can damage bacterial cell walls. The dry powder of papaya seeds was extracted by maceration method using 80% ethanol. The purpose of this study was to determine the optimal combination of HPMC and carbopol concentrations in the hand sanitizer gel of papaya seed ethanol extract which can influence the in vitro inhibition of Escherichia coli bacteria. The data analysis used in this study was one way ANOVA and then continued with the Post Hoc Tests. The results of the study obtained a yield of 6.933%. The optimum formula obtained is RUN 8 with a concentration of HPMC: Carbopol (0.25gram: 0.75gram). The results of antibacterial activity against Escherichia coli bacteria obtained an average of 44.25 mm from the two samples. The statistical results obtained stated that there was no significant difference between the concentration of A and ciprofloxacin as a positive control. Keywords: HPMC, Carbopol, papaya seeds (Carica papaya L.), Gel hand sanitizer, Escherichia coli
OPTIMASI HPMC DAN KARBOPOL DALAM FORMULASI SEDIAAN GEL ANTISEPTIK EKSTRAK ETANOL DAUN BELUNTAS DAN AKTIVITAS ANTIBAKTERI TERHADAP Staphylococcus aureus Muhammad Dienulloh Qasyfur Rohman; Iwan Setiawan; Ardy Prian Nirwana
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.566

Abstract

Beluntas leaf (Pluchea indica, L.) is one of the plants that has potential as an antibacterial, Where the leaves of Beluntas have several compounds, one of these is a flavonoid which has antibacterial activity. The aim of this research is to determine the optimum composition of HPMC and carbopol which will be formulated in the preparation of antiseptic gel ethanol extract of beluntas leaf using the SLD method. The extraction method used in this study is Maseration with ethanol as a solvent. Antiseptic gel manufacturing is done by optimizing the base of HPMC and Carbopol, Then testing the quality of the gel preparation and the results obtained that meet the requirements of the homogeneity, pH, dispersion, viscosity, consistency and stability test of the gel preparation. The optimum formula of antiseptic gel based on the simplex lattice design method is on a combination of a 4.5% HPMC base and a 0.5% carbopol. Antibacterial activity test found inhibition zone, this shows that the antiseptic gel preparation of the ethanol extract of beluntas leaves has the ability to inhibit against Staphylococcus aureus bacteria with an average diameter of the zone of inhibition by 17,66 mm.
PERBEDAAN TINGKAT PENGETAHUAN PASIEN SEBELUM DAN SESUDAH PEMBERIAN LEAFLET TENTANG CARA PENGGUNAAN DAN PENYIMPANAN OBAT TETES MATA DI APOTEK PERINTIS KURIPAN BANJARMASIN Noverda Ayuchecaria; Sahena Nurzaqia; Nur Fitriani Ahdy
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.567

Abstract

The use of eye drops must be as directed in order to obtain an optimal clinical outcome. The storage of eye drops should also receive special attention to ensure sterility. The purpose of this study was to determine differences in the level of patient knowledge before and after giving leaflets. This is an experimental research one group pre test-post test design. Data were collected prospectively. The research was conducted at the Kuripan Perintis Pharmacy, Banjarmasin. The sample in this study amounted to 50 respondents. Data were collected using a questionnaire. The research sample received intervention giving leaflets about the use and storage of eye drops. The research data were displayed in percentage form and analyzed using different test. The results showed that the level of knowledge of respondents about how to use and store eye drops before giving leaflets was in good category 15 (30%); enough 21 (42%) and less (28%). While the level of knowledge of respondents after being given leaflets was in the good category 30 (60%); enough 13 (26%) and less 7 (14%). There was a significant difference between the level of knowledge of the respondents before and after being given the leaflet (p <0.05).
EVALUASI PERESEPAN OBAT PASIEN RAWAT JALAN PUSKESMAS SUNGAI TABUK 1 KALIMANTAN SELATAN TERHADAP FORMULAIRUM KABUPATEN Okta Muthia Sari; Rollah Muhammad Arasy Hasan; Pretty Wulan Sari; Henni Selvina
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.574

Abstract

Drug formularies are a guide for health workers in choosing drugs rationally. One of the benefits of formularies is controlling quality and optimizing services for patients. The conformity of prescription drugs to formularies is important to improve the quality of service. The purpose of this study was to assess the conformity of prescription drugs at Sungai Tabuk 1 Primary Health Care against the Banjar District Formulary for the period 2019. This retrospective descriptive study was conducted in January to February 2020 at the outpatient of Sungai Tabuk 1 Primary Health, South Kalimantan. Prescribing drugs at the outpatient of the 16 therapy classes, there are 13 therapy classes 100% according to the Banjar Regency Formulary for the period 2019. Meanwhile, 3 classes of less than 100% conformity therapy include anti-infection, topical medicines for the skin, and vitamins and minerals. The mean percentage of prescription drugs at the outpatient of Sungai Tabuk 1 in accordance with the Banjar Regency Formulary was 99.15.
OPTIMASI FORMULA PATCH KOSMETIK EKSTRAK METANOL DAUN PACAR AIR (Impatiens balsamina L.) DENGAN KOMBINASI MATRIKS HPMC DAN POLIETILEN GLIKOL 400 SECARA SIMPLEX LATTICE DESIGN Yovina Ika Adiaswati; Dian Puspitasari; Disa Andriani
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.578

Abstract

Pacar air leaves contain coumarin compounds, flavonoids, quinones, and saponins which are known to have antibacterial activity. The purpose of this study was to determine the optimum proportion of the combination of HPMC and Propylene Glycol 400 and to determine the antibacterial activity of the methanol extract patch of pacar air leaves. Extraction using the maceration method with methanol. Optimization is done using the simplex lattice design, tested for physical quality. The optimum formula is then verified using the T-test. Antibacterial activity test of patch preparations was carried out by looking at the size of the inhibition zone, the inhibition diameter data obtained were processed with ANOVA statistics. The results of this research were the patch formula with a combination of HPMC (11.25 grams) and PEG 400 (3.75 grams). PEG 400 cannot be used singly because it cannot be solid. The results of the activity test of the methanol extract of the leaves of water henna against the Staphylococcus epidermidis bacteria showed that the average diameter of the inhibition zone was 15.16 ± 0.75mm. The results of one way ANOVA test obtained data of 0.096> 0.05, indicating that the positive control with the sample was not significantly different.
PEMBUATAN LULUR KRIM DARI LIMBAH KULIT BAWANG MERAH (Allium cepa L) DAN CANGKANG TELUR AYAM DENGAN EMULGATOR SPAN-TWEEN 80 Rina Kurniaty; Nadira Dina Mahyuna
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.579

Abstract

Cream scrub is a body scrub that contains slightly harsh ingredients with cream-based ingredients. In this study, onion extract (Allium cepa L.) and chicken eggshell powder were used in order to determine which emulgator concentration (Span-Tween 80) could provide the best stability of cream scrub. Onion extract was made by maceration using methanol solvent to obtain liquid extract, afterward concentrated using vacuum rotary evaporator until a thick extract was obtained. There were 3 concentration variation of emulgator used for each 100 g of cream scrub formulation, namely 1% (F1), 2% (F2), and 3% (F3). Evaluation of cream scrub included organoleptic test, homogeneity test, dispersion test, emulsion type test and pH measurement. The results showed that all three cream scrub formulations were homogeneous and the cream scrub had M/A emulsion type. The results of dispersion test showed that F2 cream scrub had greater dispersibility than F1 and F3. Emulgator span-tween 80 with a concentration of 2% provided the best stability for cream scrub formulations.
KESESUAIAN PENGELOLAAN DAN GAMBARAN PENGGUNAAN LOGISTIK FARMASI TROLI DI RUANG ICU RSUD ULIN BANJARMASIN Amaliyah Wahyuni; Alifa Husnul Khotimah
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.583

Abstract

Emergency medicine is life saving, so emergency management is important to improve emergency services. The implementation of emergency pharmaceutical logistics management must use an effective, coordinated and multidisciplinary process. The purpose of this study was to determine the percentage of suitability of emergency trolley management and the type of emergency pharmacy logistics with the highest frequency percentage of using emergency trolleys in the ICU room of RSUD Ulin Banjarmasin. This research is a non-experimental descriptive study, data were collected prospectively using observation sheets based on SPO and use sheets for emergency pharmacy logistics in the ICU room at RSUD Ulin Banjarmasin. The population and sample of this study were all observation data of emergency trolley management in the ICU Room. The sampling technique used is saturated sampling technique all populations as samples. Data analysis was performed by calculating the percentage of suitability and the data were presented in tabular form. The results showed that the overall percentage of suitability for emergency trolley on SPO was 43.4% and 56.6% unsuitable. The highest frequency of use of emergency drugs was Vascon (norefinephrine) 73.33%, while the highest medical equipment was at Surflo 20,22,24 86.67% and Spuit NGT 50cc / Spuit 50cc 86.67%.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN BAWANG DAYAK (Eleutherine palmifolia (L.) Merr) TERHADAP PERTUMBUHAN Propionibacterium acne Eka Kumalasari; Aina Aina; Noverda Ayuchecaria; Noor Aisyah
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.584

Abstract

Acne that appears can cause facial changes, in the form of swelling, redness, purulence and causing pain so that it will create an impression that is less attractive in appearance and affects one's beauty. One of the causes of acne is Propionibacterium acne. Dayak onion leaves are one of the plant that contain antibacterial compounds. The purpose of this study was to determine the antibacterial activity of ethanol extract of onion leaves on the growth of Propionibacterium acne.The antibacterial activity of this plant needs to be reviewed through with extract group with various concentrations, positive control group (clindamycin 0.1%) and negative control group (Aquadest). The results showed that the ethanol extract of dayak onion leaves had antibacterial activity against the growth of Propionibacterium acne. The diameter of the inhibition zone formed at concentrations of 20%, 40%, 60%, 80% and 100% respectively 7.25 mm (medium), 10.43 mm (strong), 15.23 mm (strong), 18, 55 mm (strong) and 22.20 mm (very strong).
HUBUNGAN KARAKTERISTIK PASIEN DENGAN TOKSISITAS HEPATOLOGI AKIBAT PENGGUNAAN 6-MERKAPTOPURIN DALAM FASE PEMELIHARAAN PADA PASIEN PEDIATRI KANKER LEUKIMIA LIMFOBLASTIK AKUT DI RS KANKER DHARMAIS JAKARTA Nazhipah Isnani; Dyah Aryani Perwitasari; Rizka Andalusia; Haridini Intan Mahdi
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.585

Abstract

Mercaptopurine is a chemotherapy drug that used in the consolidation and maintenance phase in pediatric patients with acute lymphoblastic leukemia ( ALL). Mercaptopurine is supposed to have relationship with the occurrence of toxicity in hepatology. This study was aimed to determine the patient incidence , severity and management of toxicity and risk factors that affect the occurrence of hepatologic toxicity using of 6 - MP in the maintenance phase in pediatric patients with acute lymphoblastic leukemia in Dharmais Cancer Hospital Jakarta. This research was carried out by cross-sectional observational design with data was taken retrospectively and prospectively during the period from March to April 2014. The study subjects were patient who have been getting treatment of maintenace phase in Dharmais Cancer Hospital Jakarta from 2013 until March-April 2014. The Subjects who met the inclusion criteria were 23 patients of ALL received 6 - MP in the maintenance phase. Data was collected by looking at the medical records for getting of the patient's identity and data hepatology. The result showed that there was a correlation between patient characterision on hepatology toxicity, on SGOT age and weight with SGPT both of them has significant value, it was 0,036 (P<0,05)

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