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Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 336 Documents
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STANDARISASI SIMPLISIA BAWANG DAYAK (Eleutherine bulbosa (Mill.) Urb) MELALUI ANALISIS PARAMETER SPESIFIK DAN NON-SPESIFIK Kaffah, Silmi; Silmi Kaffah; Moch. Saiful Bachri; Laela Hayu Nurani; Wahyu Widyaningsih; Muhammad Ma’ruf; Danang Prasetyaning Amukti
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2520

Abstract

Bawang dayak (Eleutherine bulbosa (Mill.) Urb) merupakan bahan alami berupa serbuk kering yang diperoleh dari umbi tanaman ini. Standardisasi sangat penting untuk memastikan konsistensi kualitas, keamanan, dan kemanjuran bagi konsumen. Tujuan penelitian ini adalah untuk mengevaluasi mutu bawang dayak yang diperoleh dari kota Sintang, Kalimantan Barat berdasarkan uji parameter spesifik dan non spesifik. Pengujian dilakukan dengan mengukur parameter non spesifik dan parameter spesifik. Hasil uji parameter non spesifik menunjukkan bahwa Simplisia memiliki kadar air sebesar 9,10%, kadar abu total 0,57%, dan kadar sari larut etanol 5,46%, menunjukkan stabilitas dan kemurnian yang baik. Uji parameter spesifik menunjukkan bahwa kandungan flavonoid total adalah 3,57 mg QE/g dan kandungan fenolik total adalah 2,05 mg GAE/g, yang menunjukkan potensi kapasitas antioksidan dan aktivitas farmakologis. Penelitian ini dapat disimpulkan bahwa umbi bawang dayak memenuhi standar mutu berdasarkan uji parameter spesifik dan non spesifik, layak digunakan sebagai bahan baku obat herbal. Penelitian lebih lanjut diperlukan untuk mengoptimalkan penggunaannya dalam formulasi farmasi.
KESESUAIAN PENYIMPANAN OBAT HIGH ALERT DI INSTALASI FARMASI RUMAH SAKIT X BANJARMASIN Ilahi, Fitrah Shafran; Rahmah; Yumassik, Abdul Mahmud; Nordin; Ainah, Nur; Istiqamah, Farida; Faqih, Muhammad
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2521

Abstract

High Alert is a type of drug that needs to be taken seriously as it can often lead to fatal errors and also has a high potential to trigger Adverse Drug Reactions. These drugs are divided into three categories, namely High Risk drugs, High Concentrate Electrolytes, and Look Alike Sound Alike/ Drug Name Look and Sound Similar. The purpose of this study was to assess the suitability of High Alert drug storage at the Banjarmasin X Hospital Pharmacy Installation based on the standard operating procedure for High Alert drug storage. The research method used qualitative observational with a cross-sectional approach. The study sample included 158 items of High Alert drugs in the Pharmacy Warehouse, Outpatient Pharmacy Depot, and Inpatient Pharmacy Depot, taken using the Total Sampling technique and data collected prospectively using a checklist sheet. Then processed with Microsoft Excel based on standard operating procedures. The results showed that the suitability of High Alert drug storage in the Pharmacy Warehouse was 99% (61 items), Outpatient Pharmacy Depot was 100% (41 items), and Inpatient Pharmacy Depot was 98% (51 items). Overall, the average suitability of High Alert drug storage in the three depots is 99% suitable in drug storage.
ANALISIS COST OF ILLNESS PASIEN DIABETES MELITUS DAN HIPERTENSI DI RSUD SULTAN SURIANSYAH Aisyah, Noor; Mahmud Yumassik, Abdul; Puteri Amalia, Senya; Raida; Muharromah, Siti
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2325

Abstract

Diabetes melitus dan hipertensi merupakan penyakit kronis yang membutuhkan terapi rutin untuk mengontrol penyakitnya. Pembiayaan penyakit tersebut dapat diukur dengan analisis cost of illness yang merupakan analisis untuk mengukur beban ekonomi penyakit pada masyarakat. Hipertensi dan diabetes melitus prevalensinya terus meningkat serta biaya perawatan yang tinggi. Tujuan penelitian adalah untuk mengetahui rata-rata Cost of Illness (COI) pada pasien hipertensi dan diabetes melitus rawat jalan dan faktor karakteristik yang mempengaruhi. Metode penelitian menggunakan teknik accidental sampling berdasarkan pendekatan prosfektif dari kuesioner dan retrospektif menggunakan data administrasi rumah sakit tahun 2024. Penelitian dilakukan di RSUD Sultan Suriansyah Kota Banjarmasin pada pasien rawat jalan dengan jumlah sampel 82 pasien diabetes melitus dan 85 pasien hipertensi. Data dianalisis menggunakan Microsoft Excel. Hasil penelitian menunjukkan rata-rata biaya Cost of Illness pada pasien diabetes melitus perepisode perawatan yaitu Rp.208.652 dengan rata-rata biaya medis langsung sebesar Rp.149.446, biaya non medis langsung sebesar Rp.20.024 dan biaya tidak langsung sebesar Rp.39.181. Sedangkan rata-rata biaya pada pasien hipertensi selama perepisode perawatan yaitu Rp.168.449, rata-rata biaya medis langsung Rp.98.264, biaya non medis langsung Rp.16.811 dan biaya tidak langsung Rp.53.676.
PROFIL PENGGUNAAN CHOP DAN RCHOP PADA PASIEN LIMFOMA NON-HODGKIN DI RSUP DR. SARDJITO Gustinanda, Rizky; Irham, Lalu Muhammad; Supadmi, Woro; Khair, Riat El
Jurnal Insan Farmasi Indonesia Vol 8 No 1 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v8i1.2529

Abstract

Non-Hodgkin lymphoma (LNH) is a heterogeneous malignancy of the lymphatic system with CHOP and RCHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone) chemotherapy regimens as main options. Local data on patient characteristics undergoing these treatments are still limited, especially at Dr. Sardjito General Hospital. This study evaluates the characteristics of LNH patients receiving both regimens at Dr. Sardjito (2020–2023). It is a descriptive observational study with a cross-sectional design. Data from patient medical records were analyzed descriptively. Of 176 patients, 80 received CHOP and 96 R-CHOP. Most were male (CHOP: 70%; R-CHOP: 60.4%) and aged >50 years, with peak age of 51–60 in CHOP (40%) and >60 in R-CHOP (44.8%). Comorbidities were found in one-third of patients. Advanced stage predominated (CHOP: 31.3% stage 4; R-CHOP: 38.5% stage 2), and most completed 6 chemotherapy cycles. Rituximab ≥550 mg was widely used in R-CHOP; cyclophosphamide >1100 mg, doxorubicin 70–79 mg, and vincristine ≥2 mg were standard in both regimens. Prednisone 100 mg was common. Diffuse Large B-Cell Lymphoma (DLBCL) dominated R-CHOP (98.96%), while CHOP patients included DLBCL (38.75%), FL, PTCL-NOS, and others. Findings highlight the importance of individualized treatment based on histopathology and disease stage.
STABILITAS ANTIOKSIDAN LOTION EKSTRAK ETANOL DAUN BUAS-BUAS (Premna serratifolia L.) Puspita, Weni; Puspasari, Heny; Kartika Sari, Dian
Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/qv5pf836

Abstract

This study aims to determine the physical stability and sunscreen activity of lotion ethanol extract of buas-buas leaf. The ethanol extract of buas-buas leaves was obtained by maceration using 70% ethanol solvent. EEDB was then formulated into a lotion with an EEDB concentration (FI: 1%, FII: 2%, FIII : 3%). The EEDB lotion formula was tested for physical stability by cycling test method using a climatic chamber at 40°C ± 2°C and 4 °C ± 2°C for 6 cycles. Tests include organoleptic, homogeneity, viscosity, pH, spreadability, and lotion type. An antioxidant test wa carried out using the DPPH method. The results of the physical stability test on the three EEDB lotion formulas (FI: 1%, FII: 2%, FIII : 3%) showed good physical stability because there were no significant differences during six cycles of storage (p>0.05) with the results of the preparations smelling typical of oleum citri, green-brown in colour, has a semi-solid, homogeneous texture, lotion type M/A, meets the requirements of pH, viscosity and spreadability with the highest average percent inhibition before and after the cycling test, namely in formula III, was 69,89 ± 0,74%.
UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETIL ASETAT DAUN UBI JALAR UNGU (Ipomea batatas L.) DENGAN MENGGUNAKAN METODE DPPH Alfiyah Cahyani Rhomah; Yoni Rina Bintari; Dian Novita Wulandari
Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/kgkq6e98

Abstract

Purple sweet potato leaves (Ipomea batatas L) have contained various bioactive compounds such as phenolic and caffeolyquinic acid has a potential pharmacological as an antioxidant. The study aimed to investigate of antioxidant potential of the ethyl acetate fraction of purple sweet potato leaves using DPPH method. It began with extracting the simplicia of purple sweet potato leaves using the Ultrasound-Asissted-Extraction (UAE) method with ethanol p.a, then multi-stage liquid-liquid fractionation with non-polar to polar solvents so that an ethyl acetate fraction was obtained as a sample. The samples are measured for antioxidant activity using the DPPH method results expressed as the IC50 value. Phytochemical screening showed that ethyl acetate fraction of I.batatas leaves was positive contained phenolic compounds and had a potential antioxidant activity of (IC50 = 5.27 μg/ml) which was included in the very strong category.
STANDARISASI EKSTRAK ETANOL BAWANG DAYAK (Eleutherine bulbosa (Mill.) Urb) MELALUI ANALISIS PARAMETER SPESIFIK DAN NON-SPESIFIK Shafala Rivani Aisyah; Moch. Saiful Bachri; Laela Hayu Nurani; Sapto Yuliani; Silmi Kaffah; Sri Rahmawati; Muhammad Ma'ruf; Danang Prasetyaning Amukti
Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/276ecv08

Abstract

Latar belakang: Bawang dayak (Eleutherine bulbosa (Mill.) Urb) merupakan bahan alami yang diolah menjadi ekstrak etanol dari umbi tanaman, dan sangat memerlukan proses standardisasi guna menjamin kualitas, keamanan, serta efektivitasnya secara konsisten bagi konsumen. Penelitian ini bertujuan untuk menilai mutu ekstrak etanol bawang dayak yang diperoleh dari wilayah Sintang, Kalimantan Barat melalui pengujian terhadap parameter spesifik dan nonspesifik. Metode: Pengujian dilakukan dengan mengukur parameter non spesifik dan parameter spesifik. Hasil: Uji laboratorium dilakukan dengan mengukur kadar air (6,31%), abu total (2,27%), dan sari larut etanol (10,84%) sebagai indikator nonspesifik yang merefleksikan stabilitas dan tingkat kemurnian bahan. Sementara itu, parameter spesifik menunjukkan kandungan flavonoid total sebesar 8,416 mgQE/g dan fenolik total sebesar 75,026 mgGAE/g, yang mengindikasikan potensi tinggi terhadap aktivitas antioksidan dan manfaat farmakologis. Kesimpulan: Berdasarkan hasil tersebut, ekstrak etanol bawang dayak dinilai telah memenuhi standar mutu dan berpotensi untuk dikembangkan sebagai bahan baku obat herbal, meskipun kajian lanjutan tetap diperlukan guna mengoptimalkan penerapannya dalam formulasi farmasi yang lebih luas.
FORMULASI DAN UJI STABILITAS BODY SCRUB EKSTRAK DAUN PEPAYA (Carica papaya L.) DENGAN VARIASI KONSENTRASI BIJI PEPAYA SEBAGAI EKSFOLIAT Dewi Mutia Azizah; Dyera Forestryana; Nur Rahmiati
Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/v4j46x43

Abstract

Body scrub is a topical formulation designed to remove dead skin cells, resulting in smoother and brighter skin. Papaya seeds (Carica papaya L.) have potential as a natural exfoliating agent, while papaya leaf extract is known to support skin regeneration. This study aimed to evaluate the physical characteristics and stability of a body scrub formulation containing papaya leaf extract with varying concentrations of papaya seeds as exfoliating agents. Papaya leaf extract was obtained using 70% ethanol as the solvent and formulated into an oil-in-water (O/W) cream with papaya seed variations of 5 g, 10 g, 15 g, 20 g, and 25 g. The evaluations included organoleptic properties, homogeneity, pH, viscosity, spreadability, adhesiveness, cream type, and physical stability using a six-cycle cycling test method. The results showed that all formulations exhibited good physical characteristics, with pH values ranging from 7.02 to 7.50, viscosity of 15,250–47,000 cPs, spreadability of 5.1–6.5 cm, and adhesiveness of 0.85–1.97 seconds. All formulations were homogeneous, physically stable, and classified as oil-in-water (O/W) creams. Formula F2 demonstrated the best physical characteristics among all tested formulations.
PERBEDAAN KUALITAS PELAYANAN PASIEN RAWAT JALAN BPJS DENGAN PASIEN UMUM DI RUMAHSAKIT JIWA SAMBANG LIHUM Paramitha, Rezky; Maulidie Alfiannor Saputera, Mochammad; Alexxander
Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/99enyw06

Abstract

Pharmaceutical services are a crucial component in determining patient satisfaction levels at Sambang Lihum Psychiatric Hospital. This study aims to analyze differences in perceived service quality between outpatient participants of the Social Security Administration Agency (BPJS) and general (non-BPJS) patients. The research employed a cross-sectional design with an accidental sampling technique based on predetermined criteria, involving a total sample of 279 BPJS patients and 61 general patients. Data were analyzed using the Mann-Whitney test. The results showed a significant value (p = 0.002 < 0.05), indicating a meaningful difference in service quality between BPJS and general outpatient groups.  
FORMULASI DAN EVALUASI SEDIAAN CLAY MASK ESKTRAK ETANOL 96% DAUN SIRIH CINA (Peperomia pellucida L.) DENGAN VARIASI KAOLIN DAN BENTONITE. M. Andi Chandra; Wahyudin Bin Jamaludin; Ariska Nurjannah Aman, A.N.
Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/pqvc9988

Abstract

Peperomia pellucida L extract exhibits antibacterial activity and may be developed into a cosmetic clay mask. Variations in kaolin and bentonite concentrations can affect the physical properties and stability of the formulation. This study aimed to evaluate the characteristics of clay mask formulations containing ethanol extract from Chinese betel leaf and to identify the most optimal formulation based on stability testing via the cycling test method. An experimental method was used with six variations of kaolin and bentonite: F1 (30% kaolin; 20% bentonite), F2 (32.5%; 17.5%), F3 (35%; 15%), F4 (37.5%; 12.5%), F5 (0%; 25%), and F6 (40%; 0%). Evaluations included organoleptic properties, homogeneity, pH (4.76–5.12), spreadability (4.05–4.37 cm), moisture content (33.3–38.01%), drying time (16–30 minutes), and viscosity (3,600–16,833 mPa·s). The results showed that all formulations exhibited good physical characteristics. Formulation F4 (37.5% kaolin and 12.5% bentonite) was the optimal formulation based on its superior stability, appropriate drying time, viscosity within the ideal range, and skin- compatible pH.

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