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INDONESIA
Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 314 Documents
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PENETAPAN KADAR FENOLIK TOTAL EKSTRAK BATANG BAJAKAH TAMPALA (Spatholobus littoralis Hassk.) MENGGUNAKAN SPEKTROFOTOMETRI UV-VISIBLE Noverda Ayuchecaria; Mochammad Maulidie Alfiannor Saputera; Rakhmadhan Niah
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.478

Abstract

Bajakah tampala (Spatholobus littoralis Hassk) is one of the most widely grown plants in Central Kalimantan but has not been widely used. This plant has been empirically used to treat various diseases by the Dayak community. Efficacy obtained is suspected due to the presence of various phenol compounds in the plant. But until now there has been no further research to determine the levels of phenols contained therein. This study aims to determine the total phenolic levels in the stem of the Spatholobus littoralis Hassk. Phenolic compounds in the stem are extracted using maceration method with ethanol solvent. Total phenolic levels were determined using the UV-visible spectrophotometric method with Follin-Ciocalteau reagents and as a comparison used gallic acid. The results showed that in phytochemical screening, the stem extracts were contained phenolic compounds, tannins and saponins. Whereas in the quantitative examination it can be concluded that the average total phenolic content of the stem of the Bajakah extract with a concentration of 500 ppm is 12.33 mg GAE/g.
REVIEW ARTIKEL : POTENSI LIKOPEN DARI BUAH TOMAT (Solanum lycopersicum L) SEBAGAI ANTIAGING TOPIKAL Dani Sujana; Diah Wardani; Nurul Nurul
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.479

Abstract

Free radicals are factors responsible for the skin's aging process. As a result of free radicals, there is a loss of electrons from its free electron pair which makes it unstable and highly reactive in its outer orbital. The effect of an odd number of electrons on free radicals, there is electron capture from other molecules around it to achieve stability. Compounds that can ward off free radicals are antioxidants. Likopen is an antioxidant with high content found in tomato fruit. Antioxidant activity of Lycopen potentially as antiaging skin. The mechanism of action of lycopene as an antioxidant that affects the skin is by lowering erythema due to exposure to UV rays and lowering the activity of Matrix Metalloproteinase-1 (MMP-1), where the enzyme is responsible for increasing the degradation of collagen dilution of the dermis. The occurrence of decreased collagen degradation resulted in reduced roughness to the skin.
PENGARUH PEMBERIAN EKSTRAK ETANOL RUMPUT LAUT MERAH (Gracilaria verrucosa) TERHADAP WAKTU PENDARAHAN (BLEEDING TIME) PADA TIKUS PUTIH JANTAN GALUR WISTAR Keni Idacahyati; Dimas Rahman Fauzi; Tresna Lestari
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.480

Abstract

Antiplatelet is a drug used to prevent excessive formation of b platelets in cardiovascular disease. The use of antiplatelet can cause resistance and side effects and cause death. Red seaweed (Gracilaria verrucosa) contains flavonoids which are polyphenol compounds which have activity can inhibiti platelet aggregation because of their ability to inhibit arachidonic acid released from membrane phospholipids through rapid coordinated activation of phospholipases from cell membranes so that the metabolic pathway of cyclooxygenase becomes inhibited. This study aims to determine the effect of ethanol extract of red seaweed on bleeding time. This method using is experimental study of 5 groups, each group consisted of 5 rats there were group of positif control, negative control, seaweed extract doses ( 300,600,1200)mg/BW with a bleeding time parameter. The results showed that the administration of 600 mg / kg BW Rats could extend the bleeding time in proportion to positive control.
TINGKAT PENGETAHUAN PASIEN GLAUKOMA TENTANG CARA PENGGUNAAN DAN PENYIMPANAN OBAT TETES MATA TIMOLOL DI POLI MATA RSUD ULIN BANJARMASIN Saftia Aryzki; Noverda Ayuchecaria
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.481

Abstract

Timolol eye drops are is the most commonly used drugs for the treatment of glaucoma. Glaucoma patients in the Eye Poly Ulin Hospital Banjarmasin tend to increase because the old glaucoma patients remain in control for monitoring and treatment while new patients increase. Information on how to use eye drops that are common causes not a few patients mistaken in their use. Therefore this study was conducted aiming to determine the level of knowledge of glaucoma about the use and storage of Timolol eye drops. This research is a non-experimental research conducted prospectively with descriptive data presentation. Research was conducted during March 2019. Population in this study were patients visiting the Eye Clinic of Ulin Regional Hospital who met the inclusion and exclusion criteria.Sampling using the saturated sampling method. Data is collected by interview using a questionnaire that has passed the test of validity and reliability. The collected data is recapitulated, processed and presented in tables and narratives. Results the level of knowledge about the use and storage of Timolol from 54 respondents studied were good knowledge level category of 42 patients (77.78%), enough knowledge level category of 9 patients (16.67%) and knowledge level category less than 3 patients (5.55%)
PENGARUH BRIEF CONSELING FARMASIS DALAM PENINGKATAN PERILAKU DAN KEPATUHAN MINUM OBAT DI RSUD ULIN BANJARMASIN Saftia Aryzki; Amaliyah Wahyuni
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.482

Abstract

Hypertension is one of the deadliest diseases in the world. As many as 1 billion people in the world or 1 in 4 adults suffer from this disease. Patient behavior by controlling the patient's blood pressure will help achieve the success of patient therapy. The purpose of this study was to determine the Brief Effect of Pharmacist Counseling in Improving Behavior and Adherence to at Ulin Hospital, Banjarmasin. The study was a quasi-experimental study using two groups. The sampling method was carried out by counsecutive sampling with simple random that met the inclusion and exclusion criteria. The sample in this study was 60 samples with 30 samples from the control group and 30 samples from the intervention group. This research was conducted at the Internal Medicine Polyclinic at Ulin Hospital from March-June 2020. The data collection technique used in this study was a questionnaire on the level of treatment behavior, the MMAS (Morisky Medication Adherence Scale) and EQ5D (Euro Quality of Life) compliance questionnaire. The results of this study were brief pharmacist counseling in improving behavior, medication adherence and the results of hypertension therapy at RSUD Ulin Banjarmasin which had a positive effect on the intervention group.
BIAYA PENGGUNAAN OBAT HIPOGLIKEMIK ORAL (OHO) METFORMIN DAN GLIMEPIRID PADA PASIEN DIABETES MELITUS TIPE II RAWAT JALAN NON BPJS DI SERANG TAHUN 2018 TIDAK BERBEDA SIGNIFIKAN Aprilla Ayu Wulandari; Rika Revina; Dhigna Luthfiyani Citra Pradana
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.484

Abstract

Diabetes mellitus (DM) is one of the four priorities of non-communicable diseases in the world, divided into two types (I and II). The incidence of type II DM in Serang is quite high, there were more than 500 outpatients in 2018, with around 70-100 non BPJS patients. This research was conducted to non BPJS patients, in order to see the difference in the cost of using Oral Hypoglycemic Drugs (OHDs), namely Metformin and Glimepirid. Similar research has never been done by UPN Veterans Jakarta in Serang. This study was an observational analytic study using a cross-sectional approach whose data were taken retrospectively. Subjects were non BPJS type II DM outpatients in 2018, aged 20-65 years, and adhering to treatment using Metformin and Glimepirid. The tools used are paper, stationery, computers, and printers. The materials used are patient data obtained from medical records, pharmaceutical installations, and finance. Data were analysed descriptively and tested its normality with Kolmogorov-Smirnov. The results showed the average cost of using Metformin was Rp 1,209,- while Glimepirid was Rp 1,228,-. So it can be concluded that the cost of using Metformin in outpatient type II DM patients in Serang in 2018, is slightly cheaper than Glimepirid.
UJI AKTIVITAS ANTIBAKTERI GEL EKSTRAK ETANOL DAUN ANGSANA (Pterocarpus indicus Willd.) TERHADAP BAKTERI Staphylococcus aureus Nelly Suryani Djamain; Vivi Anggia; Nia Fachrunisa
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.488

Abstract

Angsana leaves (Pterocarpus indicus Willd.) contain flavonoids, saponins, tannins, alkaloids, glycosides, triterpenoids, and steroids can be used as an active substances that formulated into antibacterial formulation gel. In this study, ethanolic extracts of Angsana leaves are formulated into gel form to optimize the antibacterial activity from the extracts. The purpose of this study belongs to determine the differences antibacterial activity of ethanolic extracts of Angsana leaves before and after being formulated into gel form. Antibacterial activity test was determined by using disc diffusion method due to Kirby-Bauer method. Based on the results, it showed that formulation contains 0.09 mg extract formed 8 mm inhibition zone and 9 mg extract without formulation formed 16 mm inhibition zone. By comparing the amount of extracts to the inhibitory zone, it is known that extract which formulated into a gel form has greater activity than extract without formulated.
ANALISIS EFEKTIVITAS PENGGUNAAN ANTIBIOTIKA PADA PASIEN SIROSIS HEPATIS DENGAN KOMPLIKASI SPONTANEOUS BACTERIAL PERITONITIS DI SALAH SATU RUMAH SAKIT DI YOGYAKARTA Adnan Adnan; Lolita Lolita
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.489

Abstract

Cirrhosis is a diffusion process characterized by fibrosis and changes from normal hepatic structures to structurally abnormal nodules. In general, complications that often occur in hospitalized patients are Spontaneous Bacterial Peritonitis (SBP). Many antibiotic therapies can be used for SBP, for example aminoglycosides, third-generation cephalosporins, penicillins, quinolones and sulfa groups. The purpose of this study was to determine whether there are differences in the effectiveness of antibioics used in SBP therapy. This type of research is observational analytic with cross sectional approach. Retrospective data collection in patients with cirrhosis of the liver with SBP complications in PKU Muhammadiyah Yogyakarta Hospital in 2018. Samples are all patients with cirrhosis of the liver with SBP complications who meet the inclusion and exclusion criteria. The sampling method is purposive sampling. The data taken is demographic characteristic data and clinical characteristics. Analysis of the data used in this study is multivariate analysis and different tests. There were 30 samples that met the criteria with a composition of 18 men (60%) and 12 women (40%). There were 8 people who received ceftriaxone antibiotics and 22 people got cefotaxime therapy.
AKTIVITAS BIOLARVASIDA EKSTRAK DAUN JERUK NIPIS (Citrus aurantifolia) TERHADAP LARVA NYAMUK Culex sp Siska Musiam; Agus Ariyanto; Noverda Ayuchecaria
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.490

Abstract

Lymphatic filariasis (elephantiasis) is a disease caused by filarial worms transmitted by the Culex sp. Handling this disease can be done by breaking the chain of spread by killing off the Culex sp larvae. Flavonoids, saponins, tannins, and limonoids are chemical compounds that can damage mosquito larvae. Lime leaves (Citrus aurantifolia) have been known to contain these compounds. The aim of this study was to examine the activity of extract of lime leaves on Culex sp. The extracts used were concentrations of 0.25%, 0.50%, 1.00%, and 1.50%, plus temephos 1% as a positive control, and tap water as a negative control. Each test was carried out on 20 Culex sp Instar III larvae observed for 24 hours with 4 repetitions. The results showed that the effective concentration that killed as much as 50% of Culex sp (LD50) mosquito larvae was 0.948%.
KEPATUHAN PENGGUNAAN OBAT PADA PASIEN HIPERTENSI DI INSTALASI RAWAT JALAN SALAH SATU RSUD DI WILAYAH DAERAH ISTIMEWA YOGYAKARTA Muhammad Muhlis; Alissa Jihan Prameswari
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.491

Abstract

The study aimed to determine the description of compliance with drug use and the relationship between distance of health services, duration of illness, and other illnesses to compliance with drug use in outpatient hypertension patients in the period January-February 2019 in One Hospital in the Special Region of Yogyakarta. This study was an observational study with a cross sectional design. Sampling using a questionnaire using accidental sampling technique as many as 96 patients. Compliance was analyzed using Univariate and Bivariate analysis with the chi square method. The results showed that there were 78 patients in the obedient category (81.3%). Chi square test obtained distance of health service p = 0.462; OR = 1,690 (0,6024,741) and the presence of other diseases p = 0,818; OR = 1,294 (0,464-3,613) there is no significant relationship with compliance; long suffering from hypertension there was a significant relationship with compliance p = 0.005; OR = 6.471 (1,732-24,171). Conclusion, hypertension patients are categorized as obedient 81.3% and there is no significant relationship between distance of health services and other diseases with adherence. But there is a significant relationship between the duration of suffering from hypertension and compliance

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