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MAHESA : Malahayati Health Student Journal
Published by Universitas Malahayati
ISSN : 2746198X     EISSN : 27463486     DOI : 10.3324
Core Subject : Health,
Dentistry Health Professions Nursing Public Health
MAHESA : Malahayati Health Student Journal, dengan nomor ISSN 2746-198X (Cetak) dan ISSN 2746-3486 (Online) adalah jurnal ilmiah yang diterbitkan oleh DIII Keperawatan Universitas Malahayati Lampung. MAHESA : Malahayati Health Student Journal merupakan jurnal yang memiliki fokus utama pada hasil penelitian dan ilmu-ilmu di bidang kesehatan yang dikembangkan dengan pendekatan interdispliner dan multidisiplin. Proses penerimaan naskah selalu terbuka setiap waktu, naskah yang sudah disubmit oleh penulis akan direview oleh reviewer yang ahli dalam bidang keperawatan dan kesehatan. MAHESA : Malahayati Health Student Journal telah menggunakan Open Journal System dimana penulis, editor dan reviewer bisa memantau proses naskah secara online. Dalam satu tahun MAHESA : Malahayati Health Student Journal terbit sebanyak 4 kali yaitu pada bulan Maret, Juni, September, Desember.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 1,781 Documents
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Peran Fucoidan Terhadap Angiogenesis Muhammad Yusran; Muhammad Irsan Saleh; Ernawati Sinaga; Ramzi Amin
MAHESA : Malahayati Health Student Journal Vol 6, No 8 (2026): Volume 6 Nomor 8 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i8.24160

Abstract

ABSTRACT Angiogenesis is a tightly regulated biological process that supports tissue growth and wound healing. Dysregulation of this process may lead to various pathological conditions, including cancer, cardiovascular diseases, and diabetic retinopathy. Fucoidan is a sulfated polysaccharide derived from several marine species, such as brown seaweeds and sea cucumbers. Fucoidan has been reported to possess therapeutic potential in diseases associated with angiogenesis.To elucidate the role of fucoidan in the modulation of angiogenesis, both as a pro-angiogenic and anti-angiogenic agent across various pathological conditions. This article was prepared through a literature search conducted in EMBASE/Elsevier, Google Scholar, PubMed, ScienceDirect, and the Cochrane Review for publications from 2015 to 2025. The search terms included “angiogenesis”, “fucoidan”, “fucoidan AND (pro-angiogenic OR proangiogenic)”, and “fucoidan AND (anti-angiogenic OR antiangiogenic)”. Inclusion criteria comprised English-language, relevant full-text publications (2015–2025), including both original research articles and review papers. The synthesized evidence indicates that the effects of fucoidan on angiogenesis are influenced by molecular weight, degree of sulfation, source material, extraction methods, dosage, and disease context. Low-molecular-weight fucoidan tends to exert pro-angiogenic effects by enhancing endothelial cell proliferation and migration through the PI3K/AKT and AKT/Nrf2/HIF-1α signaling pathways, thereby potentially accelerating wound healing. In contrast, high-molecular-weight fucoidan may exhibit anti-angiogenic properties by suppressing VEGF and HIF-1α expression, inhibiting vascular tube formation, and modulating mechanisms associated with tumor progression, suggesting its potential application as a therapeutic target in cancer. Fucoidan is a context-dependent modulator of angiogenesis that may exert either pro- or anti-angiogenic effects depending on its physicochemical characteristics and biological context. Keywords: Angiogenesis, Fucoidan, Pro-Angiogenik, Anti-Angiogenik.  ABSTRAK Angiogenesis merupakan proses biologis yang diatur secara ketat untuk mendukung pertumbuhan jaringan dan proses penyembuhan luka. Adanya disregulasi pada proses ini dapat menyebabkan berbagai kondisi patologis seperti kanker, penyakit kardiovaskular dan retinopati diabetik. Fucoidan adalah polisakarida sulfat yang berasal dari beberapa spesies laut, seperti ganggang cokelat dan teripang. Fucoidan dilaporkan memiliki potensi terapeutik pada penyakit yang terkait dengan angiogenesis. Untuk menguraikan peran fucoidan dalam modulasi angiogenesis, baik sebagai agen pro-angiogenik maupun anti-angiogenik pada berbagai kondisi patologis. Penulisan artikel ini dilakukan melalui penelusuran literatur pada EMBASE/Elsevier, Google Scholar, PubMed, ScienceDirect, dan Cochrane Review untuk publikasi tahun 2015–2025. Kata kunci yang digunakan meliputi “angiogenesis”, “fucoidan”, “fucoidan AND (pro-angiogenic OR proangiogenic)”, dan “fucoidan AND (anti-angiogenic OR antiangiogenic)”. Kriteria inklusi mencakup publikasi berbahasa Inggris dengan full-text yang relevan (2015–2025), termasuk artikel original maupun review. Hasil sintesis menunjukkan bahwa efek fucoidan terhadap angiogenesis dipengaruhi oleh berat molekul, derajat sulfatasi, sumber bahan, metode ekstraksi, dosis, serta kondisi penyakit. Fucoidan dengan berat molekul rendah cenderung bersifat pro-angiogenik melalui peningkatan proliferasi dan migrasi sel endotel melalui jalur PI3K/AKT dan AKT/Nrf2/HIF-1α, sehingga berpotensi mempercepat penyembuhan luka. Sebaliknya, fucoidan dengan berat molekul tinggi dapat bersifat anti-angiogenik, dengan menekan ekspresi VEGF dan HIF-1α, menghambat pembentukan tabung vaskular, serta memodulasi mekanisme yang terkait progresivitas tumor, sehingga berpotensi dimanfaatkan sebagai target terapi kanker. Fucoidan merupakan modulator angiogenesis yang dapat bersifat pro- maupun anti-angiogenik tergantung karakteristik dan konteks biologisnya. Kata Kunci: Angiogenesis, Fucoidan, Pro-Angiogenik, Anti-Angiogenik.
Korelasi Indeks Massa Tubuh dengan Parameter Fisiologis Kulit pada Mahasiswa Fakultas Kedokteran Universitas Tarumanagara Muhammad Kevin Dava Pratama; Yohanes Firmansyah
MAHESA : Malahayati Health Student Journal Vol 6, No 8 (2026): Volume 6 Nomor 8 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i8.23838

Abstract

ABSTRACT Skin health disorders are common among young adults and can be influenced by various factors, including body mass index (BMI). Obesity is known to be associated with chronic inflammation, adipokine dysfunction, and physiological alterations of the skin; however, empirical evidence among Indonesian university students remains limited. This study aimed to analyze the relationship between BMI and skin health parameters among medical students at the Faculty of Medicine, Universitas Tarumanagara. This cross-sectional study was conducted from September to November 2025. A total of 118 respondents were selected using a total sampling technique. Height was measured using a GEA stadiometer, body weight using the Karada Omron HBF-375 scale, and skin parameters were assessed using the Smart Skin Analyzer Bitmoji. Data were analyzed using univariate and bivariate methods, with Spearman correlation applied and a significance level set at p0,05. Most skin parameters showed no significant relationship with BMI, including sebum level, pores, spots, wrinkles, acne, comedones, pigmentation, skin sensitivity, and UV-induced acne (p0.05). One parameter demonstrated a significant correlation: collagen level (r=0.242; p=0.008), indicating that higher BMI was associated with higher collagen levels. Conclusion: BMI was not significantly correlated with most skin health parameters; however, it showed a significant positive association with collagen levels. These findings highlight the need for further research to explore metabolic mechanisms influencing collagen integrity in young adult populations.Keywords: Adipokines, Body Mass Index, Collagen, Skin Health, University Students.  ABSTRAK Gangguan kesehatan kulit merupakan masalah yang umum terjadi pada dewasa muda dan dapat dipengaruhi oleh berbagai faktor, termasuk indeks massa tubuh (IMT). Obesitas diketahui berhubungan dengan inflamasi kronis, disfungsi adipokin, dan perubahan fisiologis kulit, namun bukti empiris pada populasi mahasiswa Indonesia masih terbatas. Penelitian ini bertujuan untuk menganalisis hubungan antara IMT dengan parameter kesehatan kulit pada mahasiswa Fakultas Kedokteran Universitas Tarumanagara. Penelitian menggunakan desain potong lintang dan dilakukan pada September–November 2025. Sebanyak 118 responden dipilih dengan teknik total sampling. Pengukuran tinggi badan menggunakan stadiometer GEA, berat badan menggunakan timbangan Karada Omron HBF-375, sedangkan parameter kulit diukur menggunakan Smart Skin Analyzer Bitmoji. Analisis dilakukan secara univariat dan bivariat menggunakan korelasi Spearman dengan batas kemaknaan p0,05. Sebagian besar parameter kulit tidak menunjukkan hubungan bermakna dengan IMT, termasuk kadar sebum, pori, flek, keriput, jerawat, komedo, pigmentasi, sensitivitas, dan jerawat UV (p0,05). Satu parameter menunjukkan korelasi signifikan, yaitu kadar kolagen (r=0,242; p=0,008), menandakan IMT yang lebih tinggi berhubungan dengan peningkatan kadar kolagen. IMT tidak berkorelasi signifikan dengan sebagian besar parameter kesehatan kulit, namun memiliki hubungan positif bermakna dengan kadar kolagen. Temuan ini menunjukkan perlunya penelitian lanjutan terhadap mekanisme metabolik yang memengaruhi integritas kolagen pada populasi dewasa muda. Kata Kunci: Adipokin, Indeks Massa Tubuh, Kolagen, Kesehatan Kulit, Mahasiswa.
Hubungan Antara Lingkar Pinggang dengan Tekanan Darah Pada Pasien di Poliklinik Rumah Sakit Ibnu Sina Makassar Aisyah Fani Herawati; Yusriani Mangarengi; Fadil Mula Putra; Asrini Safitri; Akina Maulidhany Tahir
MAHESA : Malahayati Health Student Journal Vol 6, No 8 (2026): Volume 6 Nomor 8 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i8.24109

Abstract

ABSTRACT The prevalence of hypertension continues to increase worldwide, including in Indonesia. Hypertension is defined as an elevation of systolic blood pressure of at least 140 mmHg or diastolic blood pressure of at least 90 mmHg. This study aimed to determine the waist circumference of patients at the Outpatient Clinic of Ibnu Sina Hospital Makassar in 2025, to identify their blood pressure levels, and to examine the relationship between waist circumference and blood pressure. The study employed a descriptive-analytic design with a cross-sectional approach and involved 93 respondents. Waist circumference was measured using a standard measuring tape, while blood pressure was assessed with a sphygmomanometer following proper procedures. Data were analyzed using descriptive statistics and correlation tests. The results showed that 74 respondents (79.6%) had waist circumferences classified as central obesity, while 19 respondents (20.4%) were within the normal category. For blood pressure, 28 respondents (30.1%) were categorized as grade 2 hypertension and 20 respondents (21.5%) as grade 1 hypertension, with only a small proportion having normal blood pressure. The analysis indicated a positive relationship between waist circumference and blood pressure, where an increase in waist circumference corresponded with an increase in blood pressure. Keywords: Waist Circumference, Blood Pressure, Central Obesity, Hypertension.  ABSTRAK prevalensi hipertensi terus meningkat di seluruh dunia, termasuk di Indonesia.  Hipertensi didefinisikan sebagai peningkatan tekanan darah sistolik sedikitnya 140 mmHg atau tekanan darah diastolik sedikitnya 90 mmHg. Penelitian ini bertujuan untuk Mengetahui lingkar pinggang pasien di Poliklinik Rumah Sakit Ibnu Sina Makassar tahun 2025, mengetahui tekanan darah pasien di Poliklinik Rumah Sakit Ibnu Sina Makassar tahun 2025, mengetahui hubungan antara lingkar pinggang dengan tekanan darah pada pasien di Poliklinik Rumah Sakit Ibnu Sina Makassar tahun 2025. Penelitian menggunakan desain deskriptif analitik dengan pendekatan cross-sectional dan melibatkan 93 responden. Pengukuran lingkar pinggang dilakukan dengan pita ukur standar, sedangkan tekanan darah diukur menggunakan sphygmomanometer sesuai prosedur. Data dianalisis menggunakan statistik deskriptif dan uji korelasi. Hasil penelitian menunjukkan bahwa sebanyak 74 orang (79,6%) memiliki lingkar pinggang tergolong obesitas sentral, sedangkan 19 orang (20,4%) berada pada kategori normal. Pada variabel tekanan darah, sebanyak 28 orang (30,1%) tergolong hipertensi derajat 2 dan 20 orang (21,5%) hipertensi derajat 1, sementara hanya sebagian kecil yang memiliki tekanan darah normal. Hasil analisis menunjukkan adanya hubungan positif antara lingkar pinggang dan tekanan darah, di mana peningkatan lingkar pinggang berbanding lurus dengan peningkatan tekanan darah. Kata Kunci: Lingkar Pinggang, Tekanan Darah, Obesitas Sentral, Hipertensi.
Faktor-Faktor Budaya Keselamatan Pasien (Studi Pada Beberapa Fasilitas Pelayanan Kesehatan Swasta Di Madiun) Rizzal Selviyana Suhardi; Dewi Sri Surya Wusian
MAHESA : Malahayati Health Student Journal Vol 6, No 7 (2026): Volume 6 Nomor 7 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i7.26222

Abstract

ABSTRACT Patient safety is a top priority in healthcare, yet Patient Safety Incidents (PSIs) remain a significant problem in several private healthcare facilities in Madiun. The low reporting of patient safety incidents indicates weaknesses in the implementation of patient safety culture. This study aims to analyse the influence of professional commitment, organizational learning, transformational leadership style, meaningful recognition, and working environment on patient safety culture. This study used a cross-sectional design with a quantitative approach. The sample involved 160 nurses at Klinik Dokter Indah Madiun, Klinik Inka Madiun, Klinik Mediska, Klinik Telkom, Klinik Bakti Husada, Klinik Bakti Rahayu, Klinik Rejoagung, selected through the total sampling method. Data collection was conducted using a Likert scale-based questionnaire, while data analysis was conducted using Partial Least Squares Structural Equation Modeling (PLS-SEM). The results showed that the five independent variables had a positive and significant relationship with patient safety culture. Among these variables, transformational leadership style and professional commitment had the greatest influence. In addition, the working environment was shown to play a role in increasing the reporting of patient safety incidents. In conclusion, patient safety culture can be improved through strengthening professional commitment, organizational learning, transformational leadership style, meaningful recognition, and creating a conducive work environment. This study provides recommendations for clinic managers to improve patient safety strategies and improve the quality of health services through the development of programmes that focus on these factors. Keywords : patient safety, patient safety culture, transformational leadership, profesional commitment  ABSTRAK Keselamatan pasien merupakan prioritas utama dalam pelayanan kesehatan, namun Insiden Keselamatan Pasien (IKP) masih menjadi permasalahan yang signifikan di beberapa fasilitas pelayanan kesehatan swasta di Madiun. Rendahnya pelaporan insiden keselamatan pasien menunjukkan adanya kelemahan dalam penerapan budaya keselamatan pasien. Penelitian ini bertujuan untuk menganalisis pengaruh komitmen profesional, pembelajaran organisasi, gaya kepemimpinan transformasional, pengakuan yang bermakna, dan lingkungan kerja terhadap budaya keselamatan pasien. Penelitian ini menggunakan desain potong lintang (cross-sectional) dengan pendekatan kuantitatif. Sampel penelitian melibatkan 160 perawat di Klinik Dokter Indah Madiun, Klinik Inka Madiun, Klinik Mediska, Klinik Telkom, Klinik Bakti Husada, Klinik Bakti Rahayu, dan Klinik Rejoagung yang dipilih menggunakan metode total sampling. Pengumpulan data dilakukan dengan menggunakan kuesioner berbasis skala Likert, sedangkan analisis data dilakukan dengan menggunakan Partial Least Squares Structural Equation Modeling (PLS-SEM). Hasil penelitian menunjukkan bahwa kelima variabel independen memiliki hubungan positif dan signifikan terhadap budaya keselamatan pasien. Di antara variabel tersebut, gaya kepemimpinan transformasional dan komitmen profesional memiliki pengaruh paling besar. Selain itu, lingkungan kerja terbukti berperan dalam meningkatkan pelaporan insiden keselamatan pasien. Dengan demikian, budaya keselamatan pasien dapat ditingkatkan melalui penguatan komitmen profesional, pembelajaran organisasi, gaya kepemimpinan transformasional, pengakuan yang bermakna, serta penciptaan lingkungan kerja yang kondusif. Penelitian ini memberikan rekomendasi bagi pengelola klinik untuk meningkatkan strategi keselamatan pasien dan mutu pelayanan kesehatan melalui pengembangan program yang berfokus pada faktor-faktor tersebut. Kata kunci: keselamatan pasien, budaya keselamatan pasien, kepemimpinan transformasional, komitmen profesional
Bone Mineral Densitometry as Suggested Initial Test for Spina Bifida Patient to Prevent Minimal Trauma Fracture: A Literature Review and Case Report Victor Kurniawan Chandra; Jeffrey Jonathan Tedjajuwana
MAHESA : Malahayati Health Student Journal Vol 6, No 7 (2026): Volume 6 Nomor 7 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i7.26442

Abstract

ABSTRACT Bone fracture occurs when a force exerted against a bone is stronger than the bone can bear. This leads to pain, loss of function and sometimes bleeding and injury around the site. Spina bifida is a condition that affects the spine and is usually apparent at birth. It is a type of neural tube defect. This young spina bifida patient present with bone fracture. The patient does not have sufficient information and evaluation related to prevent spina bifida complications. A 24 years old spina bifida patient came to emergency department feeling pain at right shoulder and upper right arm since a week before admission. He had history of lifting his nephew and moving a water gallon. Swelling was revealed on the medial and lateral sides of the right upper arm, minimal deformity with hematoma, and no open wound. X-ray of the right shoulder showed fracture of the right humeral neck. Then the surgeon performed close reduction without internal fixation and immobilized the humeral. The result obtained from this procedure was satisfying and the arm could function properly. The common cause of bone fracture are trauma, osteoporosis, and overuse. Minimal trauma fracture is fracture that occur following little or no trauma and related to osteoporosis. Patients with spina bifida are at increased risk for fractures and low bone mass density. Bone mineral density have an important role in the evaluation of individuals at risk of osteoporosis, and in helping clinicians advise patients about the appropriate use of antifracture treatment. Bone mass densitometry or dual energy x-ray absorptiometry is considered useful and reliable to check bone density. This tool can be suggested as an initial screening test especially in spina bifida patient to prevent future osteoporosis and minimal trauma fracture as undesirable complications. Keywords: Bone Mineral Densitometry, Minimal Trauma, Spina Bifida, Suggested Initial Test.
Primary Raynaud’s Disease in a Young Adult: A Case Report Naufal Gusti; Maya Safira
MAHESA : Malahayati Health Student Journal Vol 6, No 2 (2026): Volume 6 Nomor 2 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i2.20742

Abstract

ABSTRACT Raynaud’s phenomenon (RP) is characterized by intermittent vasospasm and subsequent ischemia of the extremities, typically triggered by cold exposure or emotional stress. This leads to a distinct triphasic discoloration of the fingers or toes, progressing from pallor to hyperemia. This case report describes a 20-year-old woman presenting with a 1-year history of episodic bilateral finger discoloration (pallor, cyanosis, erythema) triggered by cold exposure, consistent with primary Raynaud's phenomenon. Physical examination revealed no digital ulcers or skin changes, and basic laboratory tests were unremarkable, though autoimmune serology was unavailable due to resource limitations. The patient's photograph documenting an acute attack provided valuable diagnostic support. Management emphasized conservative measures including cold avoidance and behavioral modifications, which successfully controlled symptoms. This case highlights the clinical diagnosis of primary RP in resource-constrained settings, the utility of patient-documented evidence, and the effectiveness of non-pharmacological approaches. Keywords: Ischemia, Raynaud phenomenon, Vasospasm.
Peningkatan Pengetahuan Remaja Putri tentang Anemia dan Tablet Tambah Darah Melalui Metode Pembelajaran Aktif Vanesa Aprilia Lembata; Hanna Tabita Hasianna Silitonga; Jemima Lewi Santoso; Imelda Ritunga; Antonius Yansen Suryadarma
MAHESA : Malahayati Health Student Journal Vol 6, No 7 (2026): Volume 6 Nomor 7 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i7.23737

Abstract

ABSTRACT Anemia remains a widespread health problem among adolescent girls worldwide, especially in developing countries such as Indonesia. Girls are more susceptible to anemia because they consume less iron, have unbalanced diets, and lose blood through menstruation. Anemia not only affects physical performance, but also concentration during learning, school performance, and long-term productivity. Riskesdas (2018) shows that 32% of 15- to 24-year-olds in Indonesia suffer from anemia, with the figure even higher in East Java at 42%. One of the reasons for these high figures is the lack of knowledge about anemia and the lack of awareness of the need to take iron supplements regularly. It is expected that educational measures through active learning in schools can improve young people's knowledge of anemia and its prevention. To evaluate changes in girls' understanding of anemia and iron supplements in the experimental group and control group before and after the lesson, and to compare the effectiveness of the active learning method with the poster method in improving girls' knowledge of anemia at SMA Negeri 1 Sidoarjo.This study uses a quasi-experimental design with a non-equivalent control group design. The respondents consist of 68 female adolescents, 30 of whom are in the experimental group and 38 in the control group. The experimental group received an active learning intervention in the form of true-or-false games, group discussions with case studies, and crossword puzzles. The control group received passive learning in the form of posters. The data were analyzed using the Wilcoxon rank sum test and the Mann-Whitney U test. The results of the Wilcoxon test showed a significant improvement in the knowledge of the female adolescents in the experimental group with p=0.001 (p0.05). The Mann-Whitney test showed a significant difference between the experimental group and the control group with p=0.024 (p0.05). This shows that active learning methods effectively improve young girls' knowledge of anemia. Active learning methods have been shown to be effective in improving young girls' knowledge of anemia at SMA Negeri 1 Sidoarjo. Keywords: Anemia, Adolescent Girls, Knowledge, Active Learning, Iron Supplement Tablets. ABSTRAK Secara global, anemia tetap berperan sebagai salah satu gangguan kesehatan yang umum terjadi pada remaja perempuan, khususnya di kawasan negara berkembang seperti Indonesia. Remaja putri lebih mudah mengalami anemia  karena diakibatkan oleh rendahnya pemenuhan kebutuhan zat besi dari pola makan yang kurang bergizi, serta kehilangan darah akibat menstruasi. Dampak anemia tidak hanya menurunkan kemampuan fisik, tetapi juga memengaruhi konsentrasi belajar, prestasi akademik, dan produktivitas jangka panjang. Riskesdas (2018)menunjukkan bahwa pada kelompok remaja berusia 15–24 tahun di Indonesia, kasus anemia tercatat sebesar 32%, dan angka tersebut bahkan lebih tinggi di Jawa Timur yaitu mencapai 42%. Salah satu penyebab tingginya angka tersebut adalah rendahnya pengetahuan tentang anemia dan kurangnya kesadaran dalam mengonsumsi TTD secara teratur. Upaya edukasi melalui media pembelajaran aktif ini diharapkan mampu menjadi salah satu metode pembelajaran yang baik untuk meningkatkan pemahaman remaja tentang anemia dan tablet tambah darah. Menilai perubahan pemahaman remaja putri tentang anemia dan tablet tambah darah di kelompok eksperimen serta kelompok kontrol sebelum dan sesudah mendapatkan pembelajaran, serta untuk membandingkan keefektifan metode pembelajaran aktif dengan metode poster dalam meningkatkan pengetahuan remaja putri tentang anemia di SMA Negeri 1 Sidoarjo.Penelitian ini menerapkan desain quasi experimental dengan pendekatan nonequivalent control group design. Responden terdiri dari 68 remaja putri, yaitu 30 orang di kelompok eksperimen dan 38 orang di kelompok kontrol. Kelompok eksperimen diberikan intervensi pembelajaran aktif melalui permainan true or false, diskusi kelompok dengan soal kasus, dan teka-teki silang. Kelompok kontrol menerima pembelajaran pasif melalui media poster. Data dianalisis menggunakan uji Wilcoxon Signed Rank Test dan Mann-Whitney U Test. Hasil uji Wilcoxon menunjukkan peningkatan adanya peningkatan bermakna dalam pengetahuan remaja putri di kelompok eksperimen dengan p=0,001 (p0,05). Uji Mann-Whitney menunjukkan perbedaan bermakna antara kelompok eksperimen dan kontrol dengan p=0,024 (p0,05). Hal ini menunjukkan bahwa metode pembelajaran aktif efektif meningkatkan pengetahuan remaja putri tentang anemia. Metode pembelajaran aktif terbukti efektif dalam meningkatkan pengetahuan remaja putri mengenai anemia di SMA Negeri 1 Sidoarjo. Kata Kunci: Anemia, Remaja Putri, Pengetahuan, Pembelajaran Aktif, Tablet Tambah Darah.
Influencing Factors of Patients’ Choice in the Online Medical Markets: A Systematic Review Ansalmus Oron; Ernawaty Ernawaty
MAHESA : Malahayati Health Student Journal Vol 4, No 10 (2024): Volume 4 Nomor 10 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i10.15649

Abstract

Background: The telemedicine system has created a new and important way for patients to find a doctor. This research aims to identify the influencing factors of patients’ choice in the online medical market using a systematic review study.Methods: Articles published in the last 5 years in Proquest, Google Scholar, and PubMed databases were systematically reviewed. Sixteen articles that met the inclusion and exclusion criteria were selected for further review. Findings regarding the influencing factors of patients’ choice in the online medical were systematically synthesized.Results: Sixteen articles explore seven main factors of patient choice in the online medical market such as physician factors, service quality, location, trust, WoM, patient perception and illness severity.Conclusions: Our study recommends that doctors should improve their medical skills, manners, appealing channel for health, actively publicize, increase the number of online consultations appealing channel for health, the frequency of updating the doctor's quality information and show their professional level to provide better service. The quality of online service are equally important to online doctor-patient trust and thus improve their influence.
Thoracic Ectopia Cordis At Term With Severe Intrathoracic Effusion Feldi Widianto; Febriani Febriani; Donel Suhaimi; Wiwin Suhandri; Munawar Adhar Lubis
MAHESA : Malahayati Health Student Journal Vol 6, No 7 (2026): Volume 6 Nomor 7 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i7.23733

Abstract

ABSTRACT Ectopia cordis is an exceptionally rare congenital anomaly characterized by partial or complete displacement of the fetal heart outside the thoracic cavity. It represents a spectrum of defects encompassed within Cantrell’s pentalogy, a constellation of five major ventral midline abnormalities. With an estimated incidence of 5.5–7.9 per one million live births, ectopia cordis remains a profound diagnostic and management challenge in prenatal medicine. We describe a 24-year-old primigravida at 36 weeks of gestation who presented with uncontrolled hypertension and suspicion of fetal structural abnormalities. Ultrasonography confirmed a severely malformed fetal heart located outside the thoracic cavity, accompanied by marked intrathoracic fluid accumulation and persistent fetal bradycardia. Given the non-survivable nature of the anomaly and absence of feasible postnatal interventions, a vaginal termination was performed. A female neonate weighing 2900 g was delivered with Apgar scores of 4 and 5, demonstrating complete thoracic ectopia cordis. The prognosis of ectopia cordis remains extremely poor and depends largely on the type of ectopia, degree of cardiac exposure, and the presence of intracardiac or associated structural malformations. Despite advances in fetal imaging and neonatal cardiac surgery, survival is exceedingly rare. In pregnancies with lethal features, conservative prenatal management represents an ethically appropriate approach. This case underscores the importance of early diagnosis, comprehensive counseling, and multidisciplinary decision-making. Keywords: Ectopia Cordis, Congenital Anomaly, Cantrell’s Pentalogy, Fetal Diagnosis, Pregnancy Management.
Pengaruh Model Komunikasi dalam Meningkatkan Pengetahuan dan Sikap Remaja Terhadap Deteksi Dini Penyakit Tuberkulosis Uswatun Khasanah; Rusnita Rusnita; Idhar Darlis
MAHESA : Malahayati Health Student Journal Vol 6, No 6 (2026): Volume 6 Nomor 6 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i6.22978

Abstract

ABSTRACT Tuberculosis (TB) remains a public health problem; early detection among adolescents requires a communication approach tailored to the school context. This study aimed to assess the effect of a participatory communication model on adolescents’ knowledge and attitudes regarding early TB detection. A quantitative quasi-experimental study with a pretest–posttest control group design was conducted at SMAN 21 Makassar. The population comprised all 11th-grade students; a sample of 206 was calculated using Slovin’s formula (5%) and evenly allocated to an intervention group (n=103) and a control group (n=103) by class to minimize contamination. Measurements employed standardized questionnaires before and after the intervention. Assumption tests included Shapiro–Wilk and Levene; within-group analyses used paired t-tests or Wilcoxon signed-rank tests according to distribution. Results showed that, in the intervention group, mean knowledge increased from 13.21±2.10 to 16.44±1.95 (Δ=3.23±1.55; p0.001), whereas in the control group it rose from 13.08±2.05 to 13.87±2.18 (Δ=0.79±2.19; p=0.059). The proportion with “adequate” knowledge increased from 49.5% to 84.5% in the intervention group but decreased from 44.6% to 40.8% in the control group. Mean attitude scores in the intervention group increased from 11.93±2.00 to 15.67±1.98 (Δ=3.74±1.67; p0.001), while the control group showed a smaller increase from 12.04±2.05 to 13.00±2.00 (Δ=0.96±1.95; p=0.080). Conclusion: the participatory communication model effectively improves adolescents’ knowledge and fosters positive attitudes toward early TB detection, and is therefore suitable for integration into school-based health promotion programs. Keywords: Communication Model, Knowledge, Adolescents, Attitudes, Tuberculosis.  ABSTRAK Tuberkulosis (TBC) tetap menjadi masalah kesehatan publik; deteksi dini pada remaja memerlukan pendekatan komunikasi yang sesuai konteks sekolah. Penelitian ini bertujuan menilai pengaruh model komunikasi partisipatif terhadap pengetahuan dan sikap remaja terkait deteksi dini TBC. Studi kuantitatif quasi-eksperimental dengan pretest–posttest control group dilaksanakan di SMAN 21 Makassar. Populasi adalah seluruh siswa kelas XI; besar sampel 206 orang dihitung dengan Slovin (5%) dan dialokasikan seimbang ke kelompok intervensi (n=103) dan kontrol (n=103) berbasis kelas untuk meminimalkan kontaminasi. Pengukuran menggunakan kuesioner terstandar sebelum dan sesudah intervensi. Uji asumsi meliputi Shapiro–Wilk dan Levene; analisis dalam-kelompok menggunakan paired t atau Wilcoxon sesuai distribusi. Hasil menunjukkan pada kelompok intervensi rerata pengetahuan meningkat dari 13,21±2,10 menjadi 16,44±1,95 (Δ=3,23±1,55; p0,001), sedangkan kontrol 13,08±2,05 menjadi 13,87±2,18 (Δ=0,79±2,19; p=0,059). Proporsi pengetahuan “cukup” naik dari 49,5% menjadi 84,5% pada intervensi dan turun dari 44,6% menjadi 40,8% pada kontrol. Rerata sikap pada intervensi naik dari 11,93±2,00 menjadi 15,67±1,98 (Δ=3,74±1,67; p0,001), sedangkan kontrol meningkat kecil dari 12,04±2,05 menjadi 13,00±2,00 (Δ=0,96±1,95; p=0,080). Simpulan: model komunikasi partisipatif efektif meningkatkan pengetahuan dan membentuk sikap positif remaja terhadap deteksi dini TBC, sehingga layak diintegrasikan dalam program promosi kesehatan berbasis sekolah. Kata Kunci: Model Komunikasi, Pengetahuan, Remaja, Sikap, Tuberkulosis.

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