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Jurnal Buana Farma
Published by Universitas Buana Perjuangan Karawang
ISSN : -     EISSN : 27972100     DOI : 10.36805
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical chemistry.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 204 Documents
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Skrining Fitokimia Dan Aktivitas Antioksidan Ekstrak Etanol Pelepah Daun Terubuk (Saccharum spontaneum var. edulis (Hassk) K. Schum.) shofia aulia; Eko Sri Wahyuningsih; Neni Sri Gunarti
Jurnal Buana Farma Vol. 3 No. 3 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i3.842

Abstract

Utilization of terubuk leaves effectively can increase the food value of the food waste. This influenced researchers to determine the content of secondary metabolites and antioxidant activity in terubuk leaves. The purpose of this study was to identify the ethanol content of terubuk leaves through phytochemical screening and TLC analysis and to determine the antioxidant activity of terubuk leaves. This research method uses quantitative methods namely Identification of compounds by phytochemical screening, followed by chromatographic identification Thin Layer (TLC) and qualitative testing of antioxidant activity with the method DPPH (1,1-diphenyl-2-fikrihidrazyl) was measured using a Uv-Visible spectrophotometer with various concentrations of 25, 50, 75, 100, and 125 μg/mL. The results of the phytochemical screening showed that the ethanol extract of the leaves was positive for alkaloids, flavonoids, saponins, tannins, quinones, monoterpenoids and sesquiterpenoids. Thin Layer Chromatography (TLC) results were positive for Flavonoids, Alkaloids, Quinones, Tannins.The results of antioxidant research using μg/mL the ethanol extract of terubuk leaves have activity as antioxidants. The intensity of antioxidant activity of terubuk leaves was 180.148 ± 0,898 μg/mL so that from the results of this study terubuk leaves had moderate potential antioxidant activity against DPPH free radicals. Terubuk leaf ethanol extract contains secondary metabolites and has antioxidant activity.
REVIEW ARTIKEL : TELAAH PENGOBATAN MODERN GOLONGAN DIURETIK DENGAN TANAMAN HERBALNYA Indah Sari Amanatun Nisa Indah; Eko Sri Wahyuningsih; Neni Sri Gunarti
Jurnal Buana Farma Vol. 3 No. 3 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i3.869

Abstract

Hypertension is one of the most common diseases in adults and a risk factor for cardiovascular disease. Hypertension can be said to be a "silent killer" because the patient does not show symptoms before reaching a serious condition or even complications or even death. Hypertension can be treated using 5 classes, namely diuretics, angiotensin converting enzyme inhibitors (ACE Inhibitors), calcium channel blockers (CCB), beta blockers (β Blockers), angiotensinreceptor blockers (ARBs). The aim of this article was to review to find out the types of herbal plants used Has diuretic activity in hypertension. Data search was carried out using Google Scholar and PubMed. Using the keyword "hypertensive diuretic herbal plants". The sources or references obtained are journals from the last 10 years. The results obtained show that there are several herbal plants that have diuretic activity in hypertension, including cucumber (Cucumis sativus L), rosella flowers (Hibiscus sbadariffa), cloves (Syzygium aromaticum L.), tin leaves (Ficus carica L), cat's whiskers (Ortosiphon aristatus), Tomato (Solanum lycipersicum), Celery leaves (Apium graveolens), Soursop (Annona muricata L), Belimbing Wuluh (Averrhoa bilimbi L.), in some of these herbal plants there are chemical compounds that affect the diuretic process and can reduce blood pressure blood, namely Potassium which works by increasing the secretion of sodium, water and chlorine by reducing the volume of blood and extracellular fluid, and the test or method that is carried out can be made in the form of tea, juice, and can be boiled, then drunk the boiled water.
LITERATUR RIVIEW : TELAAH PENGOBATAN MODERN DAN TRADISONAL PADA PENYAKIT ASAM URAT (GOUT) Siska Ratna Dewi; Eko Sri Wahyuningsih; Neni Sri Gunarti
Jurnal Buana Farma Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i4.870

Abstract

Metabolic disorders are disorders that increase uric acid levels (hyperurasemia). This disease is often found both in Indonesia and other countries on the Asian continent. Xantahuine Oxidase Inhibitor class drugs such as allopurinol and febuxostat are recommended as the first line of treatment, but it should be noted that continuous use of Xantahunine Oxidase Inhibitors can cause side effects of toxicity in the digestive system and increase acute attacks of gout at the start of therapy. Therefore, many studies involving many herbal plants are expected to have antihyperuricemia activity because herbal plants have a lower risk of toxicity and side effects. Based on research that has been carried out, Red Ginger (Zingiber officinale var. Amarum), Bay Leaves (Syzygium polyanthum), Seruhan Herb (Peperomia pellucida (L.) Kunth, Meniran (Phyllanthus niruri Linn.), Bamboo Shoot Extract (Schizostachyum brachycladum Kurz), Wood Secang (Caesalpinia sappan L.), Tangkur Fern (Polypodium feei), White Dragon (Hylocereus undatus), Malu Princess Plant (Mimosa pudica L.), Soursop Leaves (Annona muricata L.), Sparattosperma Leucanthum, Mahkota Dewa (Phaleria macrocarpa ( Scheff.) Boerl.), Mangosteen Fruit Peel (Garcinia mangostana L.), Dioscorea tokoro Makino, Chatupatika have antihyperuricemia activity. Therefore, in this review the antihyperuricemia activity of fifteen of these plants will be discussed. The results obtained from several articles are Some of these plants have antihyperuricemia properties through xanthine oxidase inhibition tests and reduce uric acid levels in test animals, so they have the potential to be developed as drugs for hyperuricemia
ANALISIS KEPATUHAN MINUM OBAT DAN PENGETAHUAN ANALISIS KEPATUHAN MINUM OBAT DAN PENGETAHUAN PUSKESMAS KARAWANG KOTA Dedy Frianto; Resha Rosalaia; Surya Amal
Jurnal Buana Farma Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i4.883

Abstract

Penyebab kematian di seluruh dunia diakibatkan penyakit tidak menular (PTM) yaitu hipertensi, yang terjadi pada beberapa dekade terakhir cenderung meningkat di Indonesia. Pengobatan berbagai macam penyakit diantaranya hipertensi di pengaruhi oleh oleh kepatuhan minum obat, Pengetahuan serta Kualitas hidup pasien. Penelitian ini bertujuan untuk mengetahui korelasi tingkat kepatuhan minum obat dengan kualitas hidup , korelasi tingkat pengetahuan dengan kualitas hidup dan korelasi tingkat kepatuhan minum obat dengan tingkat pengetahuan. Penelitian ini Menggunakan deskriptif analitik dengan pengumpulan data secara prospektif. Jumlah responden sebanyak 35 orang, pengumpulan data menggunakan kuesioner MMAS-8, EQ-5D-5L dan VAS, Pengetahuan dan rekam medik. Analisis data menggunakan uji korelasi Spearmen. Hasil penelitian korelasi kepatuhan dengan kualitas hidup (EQ-5D-5L) didapatkan nilai p=0,003 (<0,05) dengan nilai koefisien 0,491 yang artinya terdapat hubungan signifikan dan cukup kuat. Hasil penelitian korelasi kepatuhan dengan kualitas hidup (VAS) didapatkan nilai p=0,001 (<0,05) dengan nilai koefisien 0,517 yang artinya terdapat hubungan signifikan dan kuat. Hasil penelitian korelasi pengetahuan dengan kualitas hidup (EQ-5D-5L) didapatkan nilai p=0,003 (<0,05) dengan nilai koefisien 0,481 yang artinya terdapat hubungan signifikan dan cukup kuat. Hasil penelitian korelasi pengetahuan dengan kualitas hidup (VAS) didapatkan nilai p=0,004 (<0,05) dengan nilai koefisien 0,473 yang artinya terdapat hubungan signifikan dan cukup kuat. Hasil penelitian korelasi pengetahuan dengan kepatuhan minum obat didapatkan nilai p=0,000 (<0,05) dengan nilai koefisien 0,688 yang artinya terdapat hubungan signifikan yang kuat. Semakin baik kepatuhan minum obat dan pengetahuan hipertensi maka semakin baik kualitas hidup pasien hipertensi.
HUBUNGAN FAKTOR RISIKO TERHADAP KEPATUHAN PENGOBATAN DIABETES MELLITUS DI PUSKESMAS CIKAMPEK Larasati Fauziah Yakub; Mikha Ayu Lia Ningsih; Nirwana Aulia Putri; Maya Arfania
Jurnal Buana Farma Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i4.884

Abstract

According to the International Diabetes Federation (IDF) the prevalence of DM was 366 million in 2011, and it's predicted that in 2030 it'll increase to 552 million. In 2020 as many as 1 million people in West Java suffer from DM. With 139 thousand people of whom are residents in Karawang Regency. According to WHO in 2003 only about 50% adherence rate of chronic disease treatment in developed countries. Factors that cause low levels of adherence include running out of medication, forgetting to take medication, knowledge, motivation for treatment, and family support. In addition, age, nutritional status, education level, occupation, and income can also affect medication adherence in DM patients. The purpose of this study was to determine adherence to DM treatment at the Cikampek Health Center and how the relationship between risk factors for adherence to DM treatment. This research is an analytic observational study with a cross-sectional design. The population and sample of this study were all DM patients who underwent treatment methods at the Cikampek Health Center, using total sampling. This research was conducted at the Cikampek Health Center, using MMAS-8 questionnaire and then the data were analyzed using the chi-square test. The results of the study showed that 104 respondents had low adherence to treatment at the Cikampek Health Center, 42.3% had low adherence, and there was no correlation between risk factors and DM treatment adherence. Keywords: Adherence, Diabetes Mellitus, Risk Factor
EDUKASI FARMASI TERHADAP TINGKAT Arifani Siswidiasari; Neni Probosiwi; Nur Fahma Laili; Sugeng Riyanto; Nurul Nurhanisah
Jurnal Buana Farma Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i4.887

Abstract

Asthma control level is one of the indicators to assess the success of asthma therapy. The provision of pharmaceutical education is crucial in changing respondents' attitudes in controlling and preventing recurrent asthma exacerbations. The type of research used is pre-experimental (One group pre-post-test design) which will be conducted through pre-testing first, then giving the intervention, and then providing a post-test to determine the changes that occur before and after the intervention. Data collection is done through interviews and filling out the Asthma Control Test questionnaire. In this study, a sample of 35 respondents was used. The research analysis was conducted using the Wilcoxon test. The demographic data results showed that the majority of respondents were female, 21 respondents (60%), aged 36-45 years, 14 respondents (40%), with high school education, 14 respondents (40%), occupation as a homemaker, 13 respondents (37.1%), and a history of asthma for more than 10 years, 13 respondents (37.1%). Out of 35 respondents, before receiving pharmaceutical education, there were 7 respondents (20%) well-controlled, 13 respondents (37.1%) partially controlled, and 15 respondents (42.9%) uncontrolled. The questionnaire results after providing education showed 12 respondents (34.3%) well-controlled, 17 respondents (48.6%) partially controlled, and 6 respondents (17.1%) uncontrolled. The statistical test results showed that there is an influence of pharmaceutical education on asthma control level with a significance value of 0.003.
FORMULASI SEDIAAN SHAMPO EKSTRAK ETANOL DAUN KOPI ARABIKA (Coffea arabica L.) DAN EVALUASI FISIKNYA Yahdian Rasyadi; Diana Agustin; Octaviana Gunawan
Jurnal Buana Farma Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i4.891

Abstract

A hair problem that can interfere with the appearance and beauty of hair is dandruff. One way to treat dandruff is to use anti-dandruff shampoo. Arabica coffee leaves (Coffea arabica L.) contain various chemical compounds so they have the potential to be used as active substances in shampoo preparations. The aim of this research is to develop a shampoo preparation formula for ethanol extract of Arabica coffee leaves and look at its physical evaluation. Each shampoo contains 0% (F0), 15% (F1), 20% (F2), 30% (F3), 45% (F4), 60% (F5) ethanol extract of Arabica coffee leaves and a physical evaluation is carried out. including organoleptic tests, homogeneity tests, pH tests, foam height tests, stability tests, pH tests, stability tests and viscosity tests. The organoleptic test results showed that F0 was colorless, F1-F5 were blackish green, all formulas were in the form of a thick mass and had the aroma of coffee. The examination results showed that all formulas were homogeneous; pH ranges from 5.0 to 9.0; foam height ranges from 1.62 to 3.97 cm; the preparation does not separate (stable); viscosity ranges from 1247-3011 cp. From various physical evaluation results, it can be concluded that Arabica coffee leaf ethanol extract shampoo can be made into a shampoo that meets the requirements.
ANALISIS TINGKAT ASUPAN KALSIUM DAN VITAMIN D TERHADAP KEJADIAN STUNTING PADA BALITA DI SIJUNJUNG Elsa Marsellinda; Siska Ferilda
Jurnal Buana Farma Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i4.892

Abstract

The problem of stunting is one of the nutrition problems that the Indonesian government focuses on. Calcium and vitamin D are nutrients that affect bone mineralization. Good bone mineralization during growth allows optimal linear growth. This study aims to determine the relationship between calcium and vitamin D intake in stunted and non-stunted children aged 12-59 months in Sijunjung Regency. This research method is analytic observational with cross sectional design. The research sample was children aged 12-59 months. Data analysis methods using the SPSS program. Based on the results of the study obtained based on age group, the highest stunting at the age of 24-35 months 57.14% and the lowest in the age group 48-59 months 7.14%. then the age group is not stunted, namely the age of 24- 35 months 45.45% and the lowest in the age group 48-59 months 9.09%. Based on food intake containing high calcium and vitamin D, the category is less, namely 50.00% of stunted children and 13.64% of non-stunted children, for food intake containing low calcium and vitamin D, the category is high in both stunted and non-stunted children. Based on statistical tests, there is an effect of the level of food intake containing calcium and vitamin D on the incidence of stunting (p<0.05). Based on the results of the study, it can be concluded that calcium and vitamin D intake affect the incidence of stunting in toddlers in Sijunjung.
PENGARUH BUDAYA ORGANISASI INSTALASI FARMASI TERHADAP KUALITAS PELAYANAN DALAM MENINGKATKAN KEPERCAYAAN DAN KEPUASAN PASIEN RAWAT JALAN DI RUMAH SAKIT SWASTA CIKAMPEK Andi Nurzakiah Amal; Dewi Darwati Agustini; Surya Amal
Jurnal Buana Farma Vol. 4 No. 1 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i1.893

Abstract

The availability of medicines, long waiting times and the attitude of staff in prescription services often cause patient dissatisfaction, so a study is needed on the factors that influence whether or not an organization is effective in achieving its goals, especially in pharmacy installations. There are four variables in this research, namely one independent variable and three dependent variables. The instrument used in the Organizational Culture variable is to measure interpersonal relationships between organizational members and understanding of organizational tasks. Service quality uses the 5Q model method, customer trust is generally conceptualized in 5 dimensions while customer satisfaction uses the SERVQUAL method. 100 employees and customers of pharmaceutical installations each became participants in this study, using the partial least squares technique to test the hypothesized relationship. The study results show that organizational culture has a positive effect on service quality (t-statistic value 5.2189 > t table 1.96), Service Quality has a positive effect on increasing Customer Trust (t-statistic value 13.2489 > t table 1.96). Service Quality has a positive effect on increasing Customer Satisfaction (t-statistic value 6.4256 > t table 1.96) and Customer Trust has a positive effect on Customer Satisfaction (t-statistic value 4.1696 > t table 1.96). The results of this research show that the performance of services provided by private hospitals in Cikampek can generally meet patient expectations in terms of quality of service processes, quality of objects, infrastructure, interactions and atmosphere.
FORMULASI DAN UJI ANTIBAKTERI SABUN MANDI PADAT EKSTRAK ETANOL DAUN JAMBLANG (Syzygium cumini (L) Skeels) TERHADAP Staphylococcus aureus Himyatul Hidayah; Eko Sri Wahyuningsih; Surya Amal; Ananda Kamila
Jurnal Buana Farma Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i4.894

Abstract

Staphylococcus aureus bacteria is one of the microorganisms that cause infectious diseases of the skin. Jamblang leaves (Syzygium cumini (L) Skeels) contain bioactive compounds with antibacterial potential such as alkoloids, flavonoids, saponins, steroids, and tannins. The purpose of this study was to analyze the antibacterial activity of extracts and solid soap preparations from ethanol extracts of jamblang leaves that have potential as antibacterial Staphylococcus aureus. Method: jamblang leaf simplisia powder was macerated with 70% ethanol solvent, thick extract of jamblang leaf was tested for antibacterial activity inhibition using disc diffusion method. Solid soap preparations were made with three concentrations of jamblang leaf extract addition, namely F1 (5%), F2 (6.25%) and F3 (7.5%). The results showed that the solid soap of 70% ethanol extract of jamblang leaves can inhibit Staphylococcus aureus bacteria at all three concentrations. Formulation 1 (5%) solid soap has an inhibition zone of 6.93mm ± 0.85, Formulation 2 (6.25%) 8.61mm ± 0.99 and Formulation 3 (7.5%) 11.2mm ± 1.90. This study can be concluded that the three formulations can inhibit Staphylococcus aureus bacteria.

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