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Jurnal Buana Farma
Published by Universitas Buana Perjuangan Karawang
ISSN : -     EISSN : 27972100     DOI : 10.36805
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical chemistry.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 204 Documents
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ANALISA FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN HIPERTENSI DI PUSKESMAS X KABUPATEN MALANG Neni Probosiwi; Lintang Bismantara; Elly Megasari; Nur Fahma Laili; Tsamrotul Ilmi; Arifani Siswidiasari
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1026

Abstract

Abstract Arterial blood pressure higher than 140/90 mmHg when measured in a calm state is known as hypertension. This study aims to evaluate the factors associated with the incidence of hypertension in Health Center X Malang Regency. This study used an experimental observational design with a cross-sectional approach. The number of respondents included in this study was 74 respondents. The number of samples taken was 74 respondents. Male respondents were 20 respondents (27.02%), female respondents were 54 respondents (72.98%). Respondents who experienced prehypertension were 13 respondents (17.56%), Stage I hypertension was 30 respondents (40.54%), Stage II hypertension was 31 respondents (41.90%). Independent variables include: gender, family history, physical activity, smoking habits, diet, rest needs. The dependent variable is: Hypertension. Analysis results using the square test with α = 0.05 (p < α) obtained results: gender (p = 0.009), family history (p = 0.021), physical activity (p = 0.047), smoking habits (p = 0.002), diet (p = 0.032), rest needs (p = 0.002) have a relationship with the incidence of hypertension in the elderly at Health Center X Malang Regency.
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KRATOM (Mitragyna speciosa Korth.) TERHADAP BEBERAPA BAKTERI PENYEBAB JERAWAT Maria Ulfah; Irma Erika Herawati; Endah Kartikawati
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1027

Abstract

Acne is a common disease on the surface of the skin of the face. It will appear when the oil glands are too active and is generally followed by a bacterial infection that will cause inflammation. Bacteria that can cause acne include Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis. The plant that has antibacterial activity is kratom (Mitragyna speciosa Korth). Kratom leaves have secondary metabolites that can act as antibacteria, such as alkaloids, flavonoids, and saponins. The study aims to determine the antibacterial activity of ethanol extract against some bacteria causing acne using disc diffusion methods. The concentrations of the test sample ethanol extract of kratom leaves used were 60%, 30%, 15%, and 12.5%, with the positive controls used being chloramphenicol. The results of the study showed that ethanol extract at all concentrations had a barrier zone against the growth of the bacteria P. acnes, S. aureus, and S. epidermidis with a moderate barrier response category. Where best activity is shown at a concentration of 60% kratom leaf ethanol extract against P.acnes and S.aureus
EVALUASI PERESEPAN OBAT MASA PANDEMI DAN PASCA PANDEMI COVID-19 DI PUSKESMAS LOSARANG Anis Febri Nilansari; Puja Alfin Fadillah
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1029

Abstract

Pharmaceutical services play a crucial role in patient therapy success, with prescribing errors being a common issue leading to treatment failure. The COVID-19 pandemic, caused by the coronavirus, has underscored the need for evaluating drug prescriptions during and after the crisis. This study, conducted at the Losarang Community Health Center, Indramayu Regency, aims to assess prescription patterns and drug suitability based on WHO indicators. Using a retrospective approach, patient prescriptions from July to December 2020 (pandemic) and July to December 2023 (post-pandemic) were analyzed. Results indicate notable differences in prescribing trends. During the pandemic, antivirals, antibiotics, analgesics, and vitamins were commonly prescribed, whereas post-pandemic, analgesics, antibiotics, antihypertensives, antihyperglycemics, and antacids saw increased prescription rates. However, the average number of drugs per prescription sheet exceeded WHO standards during both periods, indicating potential inefficiencies. While the percentage of generic drug prescriptions met standards (100%), antibiotic prescriptions did not comply during both phases (pandemic: 100%, post-pandemic: 44.03%). Injection preparations met WHO standards (<20%) for both periods. Notably, adherence to the health center formulary was consistent with standards (100%) during both phases. In conclusion, this research underscores the need for optimizing prescribing practices to enhance patient outcomes. Strategies to reduce the number of drugs per prescription and ensure appropriate antibiotic use are imperative, emphasizing adherence to WHO guidelines and formulary recommendations.
FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN TEH CELUP BUNGA TELANG (Clitoria ternatea. L) DAN TEH PUTIH (Camellia sinensis) Eko Sri Wahyuningsih; Farida Nur Aeni; Farhamzah Farhamzah; Neni Sri Gunarti
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1030

Abstract

if there is an increase in free radicals in an uncontrolled amount, more antioxidants are needed to minimize and neutralize the effects of free radicals. These antioxidants can come from consumed food ingredients such as tea bags with a combination of butterfly pea flowers (Clitoria ternatea. L) and white tea (Camellia sinensis) because they have the potential to provide protection from free radicals that can damage body cells. The aim of the study was to determine the levels of antioxidants that would be obtained from combining plants that have high antioxidant activity into a preparation in the form of tea bags. The method used is in vitro using UV-Vis spectrophotometry. Testing of antioxidant activity using the DPPH (1,1-Diphenyl- 2-Picrilhydrazyl) method and data analysis using the Kruskal Walls non-parametric test. In this study the results showed that butterfly pea flowers contain alkaloid compounds, flavonoids, saponins, quinones, and tannins, as well as white tea which contains alkaloids, flavonoids, saponins, quinones, and tannins. The antioxidant activity of butterfly pea flower produced an IC50 value of 262.778 ppm, white tea produced an IC50 value of 14.091 ppm, and formulations of butterfly pea flower and white tea bags that had potential as antioxidants were F1 with an IC50 value of 16.510 ppm. Preparations of teabags of butterfly pea and white tea with a concentration ratio of 50% : 50% are effective as antioxidants and are the preferred formula based on hedonic tests which include color, smell and aroma of teabag preparations.
HUBUNGAN SELFCARE DENGAN KUALITAS HIDUP PADA PASIEN DIABETES MELLITUS DI RAWAT JALAN PUSKESMAS SUKORAME KOTA KEDIRI Nur Fahma Laili; Neni Probosiwi; Tsamrotul Ilmi; Arifani Siswidiasari; Mujtahid Bin Abd Kadir
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1034

Abstract

Diabetes mellitus is a disease that is currently an important concern. Because it is a type of disease whose number of sufferers is increasing every year. Diabetes mellitus is characterized by an increase in blood glucose levels above normal fasting > 126 mg/dl. The majority of diabetes mellitus sufferers are Type 2 where insulin sensitivity occurs so that insulin cannot be produced in sufficient quantities. The factors causing type 2 DM are a bad lifestyle. Self-care is a management action carried out by diabetes mellitus patients to maintain insulin levels and plasma sugar levels within the normal range. That so minimizing the occurrence of complications and death if the quality of life is poor. The aim of this study was to determine the relationship between self-care and quality of life in outpatients with diabetes mellitus at the Sukorame Community Health Center, Kediri City. This research uses a cross sectional design. The number of samples used a purposive sampling technique with a total sample of 93 respondents. Data collection was carried out using the Summary of Diabetes Self Care Activity (SDSCA) questionnaire and WHOQOL Questionnaire- Bref. The results of data analysis were carried out using the SPSS Chi Square Test.
SKRINING FITOKIMIA DARI EKSTRAK DAUN KANGKUNG PAGAR (Ipomoea carnea Jacq) DAN UJI ANTIBAKTERI TERHADAP Bacillus subtilis Ermi Abriyani; Lia Fikayuniar; Iin Lidia Putama Mursal; Dedeh Komalasari
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1047

Abstract

Kangkung Pagar (Ipomoea carnea Jacq) leaves is one of the plants that is used as a treatment. This study aims to determine the content of secondary metabolites and antibacterial activity of kangkong pagar leaves against Bacillus subtilis. Extraction using maceration method with n-hexane, ethyl acetat and methanol. Antibacterial assay using well diffusion method. The extract concentrations used were 40%, 60%, 80% and 100%. The positive control used was Ciprofloxacin and the negative control used was DMSO 5%. Data were analyzed by one way ANOVA test followed by Post Hoc Tukey test. The results showed that the extracts of ethyl acetate, methanol and n-hexane had a minimum inhibitory concentration of 40% with inhibition zones formed of 8.23 ​​mm, 9.4 mm and 4.2 mm. Meanwhile, at the highest concentration of 100%, an inhibition zone of 12.6 mm was formed in the ethyl acetate extract, 15.23 mm in the methanol extract and 11.4 mm in the n-hexane extract. The results showed that extract of Kangkung Pagar (Ipomoea carnea Jacq)leaves was able to inhibit the growth of Bacillus subtilis bacteria.
GAMBARAN EFEK SAMPING OBAT ANTIHIPERTENSI DI INSTALASI RAWAT INAP RUMAH SAKIT UNS Dhea Asyifa Nurmalika; Risma Sakti Pambudi; Reni Ariastuti
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1050

Abstract

Drugs provide beneficial effects, but can also cause detrimental effects. Drug side effects (ESO) are conditions that arise outside of the desired effects of treatment and are different for each person. The aim of this study was to determine the side effects of using antihypertensive drugs in hypertensive patients at the UNS Hospital inpatient unit. The research is descriptive in nature with primary data from medical records and MESO sheets of hypertensive patients. The research subjects were inpatient hypertension patients at UNS Hospital who met the inclusion and exclusion criteria. The data is then analyzed using the percentage of the results for each parameter. The research results showed that out of a total of 81 patients who used antihypertensive drugs, there were 32 patients (32%) who experienced ESO. Where 7 patients used single drugs and 25 patients used combination drugs. The most common ESO from single drug use was ramipril with dry cough (25%), shortness of breath (8%), dizziness (17%) and nausea and vomiting (8%). Meanwhile, ESO in combination drugs is amlodipine and ramipril with dry cough (15%), dizziness (20%) and shortness of breath (2%).
UJI AKTIVITAS SCALP SCRUB EKSTRAK ETANOL DAUN JAMBU METE (Anacardium occidentale L.) TERHADAP JAMUR PENYEBAB KETOMBE (Pityrosporum ovale) Teofilia Alvanes Kronikel Gea; Novena Adi Yuhara; Ellsya Angeline Rawar
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1055

Abstract

A scalp that is indicated to be unhealthy will damage the aesthetics of the hair. One indication of an unhealthy scalp is dandruff. Dandruff is flaking of the scalp accompanied by itching. Dandruff is caused by the abnormal development of the fungus P.ovale. Cashew leaves have bioactive compounds that have the potential to act as antifungals including flavonoids, tannins, phenolics, saponins. The aim of this research was to determine the characteristics of the scalp scrub cream preparation of cashew leaf ethanol extract and to test the potential activity of cashew leaf ethanol extract scalp scrub against the P. ovale fungus. This research uses the agar diffusion method with the well technique used in this research. Testing began by testing the potential activity of cashew leaf ethanol extract against the P. ovale fungus with concentrations of 25, 50, and 75%, then the best concentration was selected, formulated and tested for antifungal activity. The results obtained in this study were that cashew leaf extract had an inhibitory power in the strong category, namely 25% (14.57 mm ), 50% (14.9 mm ), 75% (16.63 mm ) against P. ovale. Apart from that, the results of the analysis using the Kruskal Wallis test of the scalp scrub cream preparation of cashew leaf extract at concentrations of 25%, 50%, 75% can inhibit P. each concentration variation in inhibiting P. ovale. . The conclusion of this research is that variations in the concentration of cashew leaf extract cream have antifungal activity against P.ovale
FORMULASI, UJI ANTIOKSIDAN DAN ANTIBAKTERI SERUM GEL EKSTRAK KULIT PISANG KEPOK (Musa balbisiana) SEBAGAI ANTI- ACNE Yuniarsih, Nia; Abriyani, Ermi; Shadrina, Alliza Nur
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1056

Abstract

One skin problem that never goes away is acne, which is a skin disorder caused by excessive sebum production and can be caused by bacteria such as Propionibacterium acnes. Another factor causing acne is also due to the presence of free radicals. Compounds that can counteract free radicals are antioxidants. This study aims to determine the best formula and storage stability of serum gel of ethanol extract of kepok banana peel (Musa balbisiana) as antioxidant and antibacterial on Propionibacterium acnes bacteria. The study was in vitro with antibacterial activity test using the pitting method and antioxidant activity test using DPPH method. Serum gel preparations were made with three concentrations of kepok banana peel (Musa balbisiana) extract addition, namely formula F1 (5%), F2 (10%), and F3 (15%). Serum gel base was used as negative control and klindamisingel as positive control. This study found that kepok banana peel contains alkaloid, flavonoid, tannin and saponin compounds. Antibacterial activity has an inhibition zone against Propionibacterium acne bacteria at all three concentrations. Serum gel F1 has an inhibition zone of 12.51 ± 0.95, F2 has an inhibition zone of 17.26 ± 0.96, F3 24.08 ± 0.73. Antioxidant activity of serum gel of kepok banana peel (Musa balbisiana) showed IC50 F1 of 95.732 ppm, F2 of 51.368 ppm, F3 of 5.929 ppm. From this study, it can be concluded that serum gel Formula 3 containing 15% ethanol extract of kepok banana peel (Musa balbisiana) is the most effective formula against antibacterial and antioxidant activity.
Literatur Review Artikel : MANFAAT PENGUJIAN AMILUM DAN PROTEIN PADA LARUTAN GLUKOSA, PATI (UJI MOLISCH) DENGAN MENGGUNAKAN BERBAGAI METODE Fikayuniar, Lia; Putri, Nurhaliza; Candra, Ayu; Susanto, Nabila Tsabitah; Rahayu, Mega Septiani; Azalia, Riza Khaila; Azizah, Sella Siti Nur
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1085

Abstract

The testing of starch and protein in glucose and starch solutions was conducted using the Molisch test and other methods. Glucose, as a monosaccharide, serves as the main energy source, while starch, being a polysaccharide, must first be broken down into monosaccharides before it can be utilized. Carbohydrates, such as glucose and starch, provide energy and support food metabolism and characteristics such as taste, color, and texture. The methods applied in this review include literature studies on the chemical testing of starch and protein, focusing on the Molisch test for detecting carbohydrates in biological samples. Various approaches, including color-change-based methods and other analytical techniques, were used to measure starch and protein in glucose and starch solutions. The review findings highlight the importance of a thorough understanding of starch characteristics and its modification to enhance its utility in the food and pharmaceutical sectors. These findings support the use of pregelatinized starch and the exploration of alternative carbohydrates sources to improve food quality and variety. Qualitative tests, such as Benedict's, detect reducing sugars in foods, while temperature increases affect the moisture content and compaction of starch, especially in pregelatinized cassava starch. In conclusion, starch testing methods like iodine and Molisch tests are effective for analyzing starch and carbohydrates, while the ratio of starch to water and temperature play key roles in influencing the physical properties of starch.

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