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INDONESIA
Jurnal Buana Farma
Published by Universitas Buana Perjuangan Karawang
ISSN : -     EISSN : 27972100     DOI : 10.36805
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical chemistry.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 204 Documents
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ISOLASI GELATIN DARI BERBAGAI BAHAN BAKU HEWANI : REVIEW JURNAL Devia Setyaningsih; Kokom Gunawan; Melisa Puspitasari; Nieda Berliana Eiko; Neni Sri Gunarti
Jurnal Buana Farma Vol. 3 No. 1 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i1.779

Abstract

Indonesia is a country that is rich in a variety of natural resources, one of which is animal. Therefore, the isolation of gelatin from various other types of animals began to be developed. Gelatin is the result of the decomposition of animal protein which has found many functions in both the food and pharmaceutical fields. Gelatin is used as a stabilizer, gelling agent, binder, thickener, and emulsifier. The method used is to search for research journal literature through electronic databases such as Google Schoolar and Sciene Direct. The results of several studies show that gelatin has water content, ash content, protein content and fat content with several different animal raw materials.
SKRINING FITOKIMIA DAN UJI ANTIOKSIDAN EKSTRAK DAUN KANGKUNG PAGAR (Ipomoea carnea Jacq) Ermi Abriyani; Lia Fikayuniar; Arie wichandar
Jurnal Buana Farma Vol. 3 No. 1 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i1.780

Abstract

The Kangkung pagar (Ipomea carnea Jacq) leaves the one source of antioxidant activity. This plant is used as traditional medicine and has potensially anti-oxidant, anti-microbial, immunostimulant, anti-cancer, liver protector and many pharmacological activities. Antioxidant can neutralize of free radicals by inhibiting the occurrence of oxidant. The aim of this study to determine of result of phytochemical screening, antioxidant activity by DPPH and FRAP methods. Methods of this study are phytochemicals screening, extraction of Ipomea carnea Jacq leave by maceration with ethanol 96%., antioxidant assays by DPPH and FRAP by determine EC50 value and the absorbances from spectroscopy UV Vis. . The result of phytochemicals screening are appear of alkaloids, flavonoids, terpenoids, steroids, saponins and tannins and antioxidants assays result EC50 value by FRAP methods were n-hexane (27.08 ppm, ethyl acetate 55.53 ppm, ethanol 68.23 ppm. While the results EC50 by DPPH methods were n-hexane 71.89 ppm, ethyl acetate 48.31 ppm and ethanol 41.07 ppm. It concluded that ipomea carnea Jacq. It can be concluded that the leaves of Ipomea carnea Jacq are a potensial source of antioxidants.
REVIEW ARTIKEL: SENYAWA FITOKIMIA SERTA AKTIVITAS FARMAKOLOGI CACING Berlianna Nur Afiddah; Firlie Bastia Putty Zahra; Indriani Sukmawati; Mira Octaviani Malik; Satrio Adi Putra; Sri Ayu Winarti; Qori Putri Suciyanti; Windi Ikhtianingsih; Neni Sri Gunarti
Jurnal Buana Farma Vol. 3 No. 2 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i2.570

Abstract

Cacing merupakan spesies yang banyak ditemukan, memiliki tubuh yang kecil dan lunak tidak bercangkang berbentuk simetri bilateral atau bilateral simetri. Cacing diketahui mampu dijadikan alternatif pengobatan bagi masyarakat dikarenakan dalam tubuh cacing mengandung banyak senyawa kimia yang memiliki berbagai macam aktivitas farmakologi, maka dari itu dilakukan review artikel ini dengan tujuan mengetahui aktivitas farmakologi serta kandungan kimia dari spesies cacing. Pencarian data dilakukan menggunakan Google Scholar dan PubMed. Menggunakan kata kunci “aktivitas farmakologi cacing” “pharmacologycal activity of worm”. Sumber atau referensi yang diperoleh merupakan jurnal dari 10 tahun terakhir, Original Research dan Review/Open Review berbahasa Indonesia dan inggris. Hasil yang diperoleh berbagai macam jenis cacing dari berbeda jenis memiliki aktivitas farmakologi seperti Cacing Tanah (Pheritema sp.) memiliki aktivitas sebagai antibakteri karena mengandung senyawa aktif Alkaloid; Siklo-(fenilalanil-prolil) dan sedanolide. Cacing laor (Lysidice Oela) memiliki aktivitas antibakteri karena mengandung senyawa aktif Bromophenol; Asam Laktat (BAL. Cacing Tanah (Lumbricus Rubellus) memiliki aktivitas antioksidan dan antitumor karena mengandung senyawa aktif Lumbricin dan Cairan selom (CFL). Cacing tanah (Pheretima aspergillum) memiliki aktivitas Osteoporosis dan Antiasma karena mengandung senyawa aktif Gli-colipoprotein (G-90), histamin dan ovalubumin. Cacing Biru (Peryonix excavatus) memiliki aktivitas antibakteri karena mengandung senyawa aktif alakolid. Cacing Tambelo (Bactronophorus) memiliki aktivitas antikanker karena mengandung senyawa aktif flavonoid dan tannin, Cacing Tanah (Eudrilus eugeniae) memiliki aktivitas antidiabetik dan antioksidan karena mengandung senyawa aktif fenolik dan protein lendir. Cacing Laut (Eunice siciliensis) memiliki aktivitas antidiabetik dan antimikroba karena mengandung senyawaa aktif alkaloid dan flavonoid.
ISOLASI JENIS ASAM LEMAK DARI BERBAGAI BAHAN BAKU : ARTIKEL REVIEW Oktavia Rajebi; Adinda Putri Sabrina; Farida Nur Aeni; Aghnia Ahda; Neni Sri Gunarti
Jurnal Buana Farma Vol. 3 No. 2 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i2.581

Abstract

Fats or triglycerides are compounds derived from glycerin with three fatty acids, which in the intestine are hydrolyzed into their components. Fatty acids can be obtained from various sources, both animal and vegetable. Fatty acids derived from animal fats are unsaturated fatty acids contained in fish oil. Fatty acids derived from several types of vegetable oils, such as palm oil and cocoa butter, contain saturated fatty acids consisting of palmitic acid (C16H31COOH) and stearic acid (C17H35COOH). Obtaining fatty acids can be conducted by the isolation method, so that the type of fatty acids contained in a sample can be determined, the purpose of this study is to determine the types of fatty acids isolated from various sources of raw materials using the literature review study method. The results of various studies show that fatty acids can be obtained from various natural materials such as animal and vegetable products, including oil palm skin, shark liver oil, catfish oil, wet and dry Moringa seeds, nutmeg seed oil, melinjo fruit seeds, marine yeast oleaginous, olive oil, and fusarium verticilloides species. The types of fatty acids obtained were oleic acid, palmitic fatty acid, DHA, omega 3 and omega 6, trimyristin fatty acid, isanic acid, linoleic acid, stearic acid, palmitoleic acid. So that by isolating the sample, it can be known the type of fatty acids contained in it, both from animals and plants.
PEMANFAATAN KOLAGEN DARI HEWAN Retna Ayu Septiani; Dinda Aisyah; Sylva Ayu Widya Cahyati; Farid Ahmad; Neni Sri Gunarti
Jurnal Buana Farma Vol. 3 No. 2 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i2.600

Abstract

The use of animals is not only used as a raw material for food, but on the other hand it turns out that animals can be used as important biomaterials for medical applications such as collagen. This review article discusses the utilization of collagen from various types of animals according to the relevant parameters. Article reviews are expected to provide scientific information about the various types of collagen in animals. The method used is literature study by looking for several different journal sources. The inclusion data used in this review are journals for the last 10 years (2012-2022). Collagen is usually found in the skin of cows and pigs, but these two animals are still a problem in Indonesia. Apart from these two, collagen can also be found in mammals such as buffalo and chickens, but they need to be slaughtered to get the halal aspect. Collagen can also be found in marine life such as sea urchins, tuna, catfish, skipjack tuna, sea catfish, milkfish, tilapia, machete fish, cod, green mussels, blood clams, and gamma sea cucumbers.
AKTIVITAS ANTIOKSIDAN PADA EKSTRAK JANTUNG PISANG AMBON Musa paradisiaca var sapientum L) DENGAN METODE DPPH Lia Fikayuniar; Ermi Abriyani; Suamiyati; Aghnia Ahda
Jurnal Buana Farma Vol. 3 No. 2 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i2.785

Abstract

Banana heart has many benefits for the body, the potential as an antioxidant owned by the ambon banana heart is needed by the body to delay, slow down and prevent the risk caused by free radicals. The purpose of this study was to compare extracts from the heart of Ambonese bananas (Musa paradisiaca var. sapientum L) that can produce the best antioxidant activity. The antioxidant test was carried out using the DPPH (1,1-diphenyl-2-pikrilhydrazil) method, this antioxidant activity test was measured using a UV-Visibe spectrophotometer. The results of the study used three extracts namely ethanol extract, ethyl acetate extract and n-hexane extract of ambon banana heart has activity as an antioxidant. The intensity of antioxidant activity successively from the highest was ethanol extract of 71,129 μg/mL (strong), n-hexane extract of 101,990 μg/mL (medium), ethyl acetate extract of ambon banana heart of 135,311 μg/mL (medium) so that of the three extracts that have the strongest antioxidant activity potential against DPPH free radicals is ambon banana heart ethanol extrac
KARAKTERISASI KATEKIN DAN UJI AKTIVITAS ANTIBAKTERI EKSTRAK BUNGA KANGKUNG PAGAR (Ipomea carnea) Ermi Abriyani; Iin Lidia Putama Mursal; Lia Fikayuniar; Hasnimar hasnimar
Jurnal Buana Farma Vol. 3 No. 2 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i2.800

Abstract

According to several studies, Kangkung Pagar (Ipomoea carnea Jacq.) that have many beneficial properties. Theaim of this study are to characterize the secondary methabolites from ethanol extract and determine antibacterialactivity against Pseudomonas aeruginosa. Methode s of this study are maceration by ethanol, fractionation bycolumn chromatography and antibacterial activity assay by disc diffusion method. Melting point of compound139-140ºC. The results from characterization by Uv-Vis and IR spectroscopy is flavan 3-ol or catechin. Theresult of antibacterial activity against psudomonas aeruginosa had strong level of activity.
Formulasi dan Uji Antioksidan Serum Spray Gel Ekstrak Etanol Bunga Kertas Nia Yuniarsih; Himyatul Hidayah; Ayu Andhini
Jurnal Buana Farma Vol. 3 No. 3 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i3.808

Abstract

Debu, asap, polusi udara, bahkan paparan radiasi matahari merupakan pemicu timbulnya masalah pada kulit, tidak hanya itu barang elektronik yang biasa dipakai pun bisa mengakibatkan adanya radikal bebas seperti handphone, computer/laptop. Radikal bebas merupakan senyawa yang memiliki electron yang tidak berpasangan akibatnya, proses penuaan dini pun akan terasa cepat. Senyawa antioksidan, berperan penting dalam penanganan adanya radikal bebas di dalam tubuh. salah satu tanaman yang dapat dimanfaatkan sebagai antioksidan adalah bunga kertas (Bougainvillea glabra Chois). Penelitian ini bertujuan untuk mengetahui efektivitas formula serum spray gel ekstrak bunga kertas yang diformulasikan dengan berbagai konsentrasi sediaan yaitu F1 3%, F2 5%, dan F3 7%. Metode yang digunakan adalah metode DPPH (2,2 Difenil 1 Pikrilhidrazil) dengan alat spektrofotometri UV-Vis dengan Panjang gelombang 517nm dan uji evaluasi sediaan serum spray gel ekstrak etanol bunga kertas dengan parameter uji seperti organoleptis, pH, viskositas, daya sebar, daya lekat, dan pola penyemprotan. Pada penelitian formula serum spray gel ekstrak bunga kertas (Bougainvillea glabra Chois) memiliki nilai IC50 F1 (24,3877 µg/mL), F2 (24,2686 µg/mL), F3 (24,5451 µg/mL) dan untuk uji parameter organoleptis sediaan serum spray gel ini memiliki bau khas ekstrak disertai bau sedikit asam berwarna kuning dan tekstur setengah gel cair, dengan viskositas dimulai dari 1000-2500 cpoise dan pH sesuai dengan pH kulit serta daya lekat <1 detik dan daya sebar yang menyebar dengan baik, dapat disimpulkan bahwa formula serum spray gel ekstrak etanol bunga kertas memiliki efektivitas antioksidan sangat kuat dan memenuhi uji syarat evaluasi fisik sediaan serum spray gel ekstrak bunga kertas.
EVALUASI MUTU PELAYANAN FARMASI KLINIK PADA PUSKESMAS PATTALLASSANG DI KABUPATEN TAKALAR Helmatiana Tandirogang; Ismail Ibrahim; Ida Adhayanti
Jurnal Buana Farma Vol. 3 No. 3 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i3.828

Abstract

One of the government's efforts to realize health development for the community is to create a Community Health Center (Puskesmas). The Puskesmas is responsible for providing comprehensive, integrated and sustainable first-level health service activities. Pharmaceutical care (pharmaceutical care) has undergone a paradigm shift from initially only focusing on drug management (drug oriented) to developing into services that also aim to improve the quality of life of patients (patient oriented). Standard clinical pharmacy is very important to note because it is directly related to patients so that it can have an impact on reducing the length of patient care and reducing therapy costs. 74 of 2016. This research is a quantitative descriptive study using observational data and retrospective data at the Pattallassang Health Center in Takalar District. Based on the results of the study, it was found that the percentage of conformity of the quality of clinical pharmacy services at the Pattallassang Health Center, Takalar Regency, based on Permenkes Number 74 of 2016, was 38.88% in the unfavorable category. This is because there are 11 assessment indicators (prescription review, labeling, delivery accompanied by information, polypharmacy, counseling, drug information service documentation, visit documentation, MESO documentation, PTO documentation, drug costs per prescription visit, and number of items per prescription) that do not meet standards and for those that meet there are 7 indicators (time to prescribe, generic preparations, use of antibiotics in non-specific diarrhea, ORS and zinc for diarrhea, antibiotics in ARI, injections and patient satisfaction) out of 18 research indicators.
TINGKAT KEPATUHAN PENGGUNAAN OBAT ANTI TUBERKULOSIS (OAT) PADA PASIEN RAWAT JALAN DI PUSKESMAS CILAMAYA KARAWANG Masita Sari Dewi; Nadia Sagita; Ike Permana Sari
Jurnal Buana Farma Vol. 3 No. 3 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i3.836

Abstract

Background Pulmonary tuberculosis is a direct infectious disease caused by Mycobacterium tuberculosis. The level of patient compliance in taking anti-tuberculosis drugs regularly until they are complete and compliant is one of the factors that determine success in the treatment of pulmonary tuberculosis. The aim was to determine patient characteristics, level of patient adherence and the relationship between the level of adherence to the use of anti-tuberculosis drugs at the Cilamaya Health Center. This research method is a descriptive quantitative approach with a quantitative approach. The tools used for data collection were researchers using a questionnaire at the Cilamaya Health Center for the April-May 2023 period. The results of the study based on gender, the amount of data collection was carried out at the Cilamaya health center, male patients were 54%, age in the age range 15-34 years was 63.5%, high school education was 34.9%, private employee employment was 25.9%, length of treatment of patients 2 months as much as 47.6%, good knowledge as much as 79.4%. In conclusion, the level of patient adherence to the use of anti-tuberculosis drugs (OAT) at the PU Health Center, good adherence rates of 23.8%, moderate 33.3% and poor adherence of 42.9%, patient characteristics include work, knowledge have a significant relationship based on the results of the level of adherence Anti Tuberculosis Drug (OAT) patients because the p value obtained is less than the significant value used, namely 0.005. Value of work (p = 0.001) and knowledge (p = 0.030).

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