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The Avicenna Medical Journal
Published by Universitas Islam Negeri Syarif Hidayatullah Jakarta
ISSN : 27209563     EISSN : 2720 9563     DOI : 10.15408/avicenna.v1i1.15639
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
The Avicenna Medical Journal, the official journal of Faculty of Medicine Universitas Islam Negeri Syarif Hidayatullah Jakarta, presents multidisciplinary scientific papers which describe innovative research spanning the entire spectrum of medical aspects both basic science and clinical aspects. It addresses scientists and researchers to publish novel research that is mechanism-based, hypothesis-driven, and focus on significant issues include, but are not limited to: Basic research and biomedical approach on the disease Clinical research Social and other aspects in the integrated focus on solving medical problems Research may involve either in vitro or in vivo or in silico approaches. The Avicenna Medical Journal receives research articles, review articles, and case reports. Appearing 2 times in a year under peer review, The Avicenna Medical Journal actively participates in solving the medical problem and its related aspects.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 88 Documents
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Effect of 12 Weeks Vitamin D Supplementation (Alphacalcidol) on Blood Pressure in Elderly Women Patients Achmad Zaki; Nida Nabila; M. Djauhari Widjajakusumah; Witri Ardini; Mery Nitalia
The Avicenna Medical Journal Vol 2, No 2 (2021)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v2i2.23785

Abstract

Background : Cardiovascular disease have overtaken communicable disease for being the main killer worldwide. Hypertension or high blood pressure is one of the risk factors. Elderly women statistically have a high prevalence of hypertension. Vitamin D is known to affect blood pressure and many studies showed the association between vitamin D and blood pressure with varying result. This study aim to evaluate the effect of vitamin D supplementation (alphacalcidol) for 12 weeks and change in blood pressure of elderly women patients in community health service clinic (KPKM) Medical Faculty Syarif Hidayatullah State Islamic University of Jakarta (FK UIN Jakarta), with pre and hypertension grade 1 patients in majority. Methods :  Analytical pre-post study design was conducted as a part of an RCT (Randomized Controlled Trial) studies with 106 participants of elderly women (45 intervention group, 61 control group).Results : Vitamin D deficiency in the intervention group significantly decreased post-supplementation from 22.2% to 8.9%. Subgroup analysis showed the decrease in blood pressure is greater in the subgroup middle-age elderly than young-age elderly category. Even though there was a significant change in the diastolic blood pressure in the subgroup of middle-age elderly post supplementation (p=0.03), Mann-Whitney statistical analysis showed that 12 weeks vitamin D supplementation (alphacalcidol) did not significantly effect the pre and post systolic nor diastolic blood pressure (p>0,05). Conclusion : The study did not found significant effect of 12 weeks Vitamin D (alphacalcidol) supplementation on blood pressure in elderly women patients.
High Risk Primary Percutaneous Coronary Intervention (Pci) in Patient with Acute Stemi Anterior, Chronic Kidney Disease, and Confirmed Covid-19 Dede Moeswir; Fadhil Muhammad; Putri Nurbaeti
The Avicenna Medical Journal Vol 2, No 2 (2021)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v2i2.23931

Abstract

Background: An acute ST-elevation myocardial infarction (STEMI) anterior occurs due to occlusion of left anterior descending artery (LAD) branch of left coronary artery. The occlusion causing transmural myocardial ischemia which in turn to myocardial infarction due to myocardial injury or necrosis. Not only Primary Percutaneous Coronary Intervention (PCI) should be performed in STEMI less than 120 minutes as the risk of the adverse events would increase if exceeding the total ischemic time, but also the procedure can be high risk in patients with multiple clinical factors or comorbidities which can increase the risk of complications.Case Report: We report a case of a 57 years old man who presented Acute STEMI Anterior, Coronary Artery Disease (CAD) 3 Vessel Diseases (VD), Hypertension Heart Disease (HHD), Chronic Kidney Disease (CKD) on Hemodialysis (HD), with COVID-19 confirmed.Results: The left coronary artery was successfully stented by PCI and Coronary Angiogram (CAG) procedures with TIMI 3 flow, minimal bleeding and others complications.
The Relationship Between Adequacy of Hemodialysis and Anemia in Chronic Kidney Diseases (Ckd) Patients Undergoing Hemodialysis in Dialysis Unit, Fatmawati Hospital Leo Ginting; Abdul Aziz; Wulandari Wulandari; Dwi Budi Lasono
The Avicenna Medical Journal Vol 2, No 2 (2021)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v2i2.17754

Abstract

Background: Anemia is a common problem that often occurs in patients with CKD undergoing hemodialysis. 56.5% of hemodialysis patients were still have anemia, while on the other hand, the achievement of hemodialysis.  adequacy only reached 52.7%. Disparity that data is the basis for this research. The aim of this study is to analysis the relationship between the achievement of hemodialysis adequacy with the incidence of anemia in patients with CKD undergoing hemodialysis.Methods: This study uses a descriptive correlation with a cross sectional approach to the analysis of the independent variable (HD Adequacy) and the dependent variable (Anemia). The relationship between these variables was tested using the Chi Square test.Result: The study was conducted on 134 hemodialysis patients aged 13-86 years, the most common vascular access was AV fistula (68.7%), and women were the most respondents (55.2%). The Kt / V value in this study was 1.67 (1.03-2.75) and an adequate one was 54.5%. Adequate URR reached 80.6% with a mean of 75.13 ± 6.38. The incidence of anemia reached 53.7% with the Hb value at 8.93 ± 2.82 mg / dl. The results of the Chi Square test showed that HD adequacy (Kt / V and URR) with the incidence of anemia had P values of 0.670 and 0.217.Conclusion: There is no significant relationship between HD adequacy and the incidence of anemia
Body Image In Female Medical Students, Syarif Hidayatullah State Islamic University, Jakarta, Indonesia: Descriptive Study Tasya Qonitah Salsabila; Marita Fadhilah; Isa Multazam Noor
The Avicenna Medical Journal Vol 3, No 1 (2022)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v3i1.27315

Abstract

Background: Body image issues can be a problem for undergraduate female college students. It happened because women pay more attention to their physical appearance than men. In addition, the ages of undergraduate female college students are generally in the young adult age range, where young adult women are found to often experience problems related to body image. Furthermore, some characteristics of campus life may cause female students to be more susceptible to body image concerns. This study aimed to describe the body image in preclinical female students of the Faculty of Medicine, Syarif Hidayatullah State Islamic University Jakarta. Methodology: This study is an observational analytic study with a cross-sectional approach that applied to preclinical female students of the Faculty of Medicine, Syarif Hidayatullah State Islamic University Jakarta, which was selected using the cluster random sampling method. Data were collected by looking at respondents' answers to The Body Appreciation Scale-2 (BAS-2) questionnaire to assess the body. Results: In this study, 120 respondents were collected from the class of 2018, 2019, and 2020 with the age range of 18-22 years. Based on the results of this study, it is known that the majority of research respondents have a negative body image (58.33%). Conclusion: The majority of research respondents have a negative body image (58.33%).
The Effect of Ramadan Fasting on Serum Malondialdehyde Levels as Indicator of Oxidative Stress and Cellular Damage Annisa Nadia Utami; Risahmawati . .; Muniroh . .
The Avicenna Medical Journal Vol 3, No 1 (2022)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v3i1.19716

Abstract

Background: Ramadan fasting is one of five pillars of Islam. Fasting is to refrain from eating and drinking from sunrise (sahur) to sunset (ifthar). Ramadan fasting has been shown to impact on body systems in different manners. One of the benefits of Ramadan fasting is protection against oxidative stress and cellular damage. Malondialdehyde (MDA) is a product of free radicals (hydroxil radicals) with polyunsaturated fatty acids (PUFAs) produced from lipid peroxidation of cell membranes. This paper aims to determine the effect of Ramadan fasting on serum MDA levels.Methods:  The design of this study is quasiexperimental with one group pre and post design. The sample of this study was 16 preclinical students of FK UIN Syarif Hidayatullah Jakarta who performed Ramadan fasting for 17 consecutive days. Blood samples were taken 1 day before Ramadan fasting and 18 days of Ramadan fasting to measure serum MDA levels. The study was conducted in the biochemical laboratory of FK UIN Syarif Hidayatullah.Results: The mean serum MDA levels before fasting was 0.90 ± 0.54 nmol/mL. The median value of serum MDA levels after fasting was 0.43 nmol/mL, with a range between 0.03 - 2.75 nmol/mL. Ramadan fasting decreases serum MDA levels, but the decrease that occurs on the 17th day of Ramadan fasting was not significant (p> 0.05). There was an increase in serum MDA levels in 4 subjects (25%) after Ramadan fasting.Conclusion: Ramadan fasting can reduce serum MDA levels as a marker of oxidative stress and cell damage. Further study is needed to investigate the various results in serum MDA levels after fasting.
Correlation Between Physical Activity, Body Composition, And Micronutrition Intake In Patients Of Knee Osteoarthritis At The Medical Rehabilitation Clinic, Fatmawati Hospital Jakarta In 2021 Wilis Laksari Putri Adjie; David Renardo Tidja
The Avicenna Medical Journal Vol 3, No 1 (2022)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v3i1.27066

Abstract

Background : Osteoarthritis (OA) is a degenerative joint disease associated with joint cartilage damage that usually occurs in the aging process. This study is to analyze the correlation between physical activity, body composition, and the micronutrients intake such as vitamin C, D, E, and Calsium the patients with knee OA at the Medical Rehabilitation Clinic (MRC) at Fatmawati Hospital, Jakarta in 2021.Methods: This is a cross sectional quantitative research. The samples were 45 patients who have been diagnosed with knee osteoarthritis in outpatient medical rehabilitation clinic at Fatmawati General Hospital Jakarta who met the inclusion criteria.Results : the results of statistical tests showed that there was a significant difference in the average percentage of body fat with the gradation of OA patients, p value = 0.004. However, there was no significant difference between the average physical activity score, and intake of macronutrients (energy, protein, fat and carbohydrates), BCAAs (arginine and histidine), and intake of micronutrients (vitamin C, vitamin D, vitamin D, vitamin E and Calcium)Conclusion: Percent body fat is the variable with the highest correlation among other factors.
Clinical Screening of Congenital Heart Disease in Neonates: a Literature Review on Five Studies Bentito Zulyan Pamungkas; Phaleno Pramasditomo Widaryo
The Avicenna Medical Journal Vol 3, No 1 (2022)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v3i1.27326

Abstract

Background: Diagnosing Congenital Heart Disease (CHD), particularly critical CHD in newborns, could be difficult but crucial, since the field of congenital heart surgery has shifted from initial palliation followed by final correction at a later age to stressing early repair even in the youngest individuals. Although echocardiography remains the gold standard for diagnosing CHD, simple clinical examination may be helpful in screening neonates who require further investigation and treatment. In this study, we searched and reviewed the literature on clinical screening for CHD using a simple, affordable tool that is readily available in primary health care facilities, to prove that early simple clinical examination would help physician to screen for asymptomatic CHD.Methods: We searched articles on google scholars that discuss clinical screening of CHD in neonates. Inclusion criteria is articles published within five years and exclusion criteria is articles published older than five years.Results: We found five articles eligible and pick consecutively. We found that pulse oximetry sensitivity and specificity ranged from 21.54%-77.3% and 82.65%-99.9%, respectively. Cardiac auscultation with murmur of grade ≥2 as count as positive, having high range of sensitivity and specificity, with sensitivity ranged from 17.3%-89.58% and specificity ranged from 47.36%-99.69%. When pulse oximetry and cardiac auscultation combined, three studies found that the sensitivity and specificity increased dramatically, 89.9%-95.5%, 94.7%-99.37%, respectively. Conclusion: Both cardiac auscultation and pulse oximetry was an easy, feasible method with readily available basic tools at all hospital with acceptable sensitivity and specificity to screening CHD before suspected neonates undergo echocardiography, therefore making CHD diagnosed more effective and efficient. 
The Health-Seeking Behavior of Diabetes Mellitus Patients during the COVID-19 Pandemic in Brebes Regency Hiro Putra Faisal; Chrestella Adiyatma; Dwi Tyastuti
The Avicenna Medical Journal Vol 3, No 1 (2022)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v3i1.27325

Abstract

Background: The COVID-19 pandemic in Indonesia has impacted patients with non-communicable diseases such as Diabetes Mellitus (DM). The impacts include health services, treatment management, and patients' health-seeking behavior. This study aims to determine the DM patients' health-seeking behavior in the Salem sub-district, Brebes district, Central Java.Methods: This research was a qualitative descriptive study conducted cross-sectionally using a survey. The purposive sampling technique was employed to obtain the data with a total sample of 106 respondents.Results: Most DM patients still visited health facilities during the pandemic (73%). Some efforts to control DM were regularly taking medication (27.7%) and maintaining a healthy diet (34%). However, most respondents stated that they have uncontrolled blood glucose levels (54.7%). During the pandemic, respondents communicated with health workers (75.5%), via telephone (64.2%), and through messaging applications (45.3%). In addition, they search information, especially when they felt symptoms (90.6%), and tried to find information about complications due to the coronavirus (68.9%) with the source from health workers (94.3%). Most respondents had good access (99.1%).Conclusion: The COVID-19 pandemic has resulted changes in DM patients' health-seeking behavior through all aspects. This study shows that most respondents visited health facilities, made efforts to control DM by taking the medication regularly and maintaining a healthy diet, and had high adherence to medication. In addition, respondents had an easy access to health information and communicate with health workers via telephone and messaging applications. The majority of respondents sought information about diabetes and its relationship with COVID-19 during the pandemic.
The Association between the rs35874116 Gene TAS1R2 Polymorphism with Caries Index Pelangi Mumtazdhia; Ani Melani Maskoen; Bremmy Laksono; Witri Ardini
The Avicenna Medical Journal Vol 3, No 1 (2022)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v3i1.27319

Abstract

Background: Dental caries is a multifactorial disease influenced by complex genetic and environmental factors. At least 27 gene polymorphisms have been identified that are associated with caries risk. Polymorphisms of genes encoding taste receptors, such as the TAS1R2 gene, can cause individual differences in perception and sensitivity to sweet tastes. Research shows that the TAS1R2 gene polymorphism is associated with the consumption of sweet foods, which affects increasing caries risk. This study aims to determine the relationship between the TAS1R2 gene rs35874116 polymorphism and the caries index in Tangerang Selatan population. Methods: This study is observational with a cross-sectional method involving 266 research subjects (45 males and 221 females; 20-55 years). DNA was extracted from venous blood using the Genomic DNA Mini Kit from Geneaid and the genotyping process using the rhAmp-SNP assay kit, which was analyzed using RT-PCR. Dental caries was assessed by calculating D(decayed), M(missing), and F(filled) on permanent teeth. The hypothesis between the TAS1R2 genotype and the DMF-T index was tested using the Mann-Whitney test, while the comparison between the TAS1R2 genotype and caries risk was tested using Kruskal-Wallis' test. The results of the study were considered significant if p<0.05. Results: The minor allele frequency was 16.5%. The proportion of TT, TC, and CC genotypes were 71.%, 24.1%, and 4.5%, respectively. According to WHO classification, the DMF-T index of all research subjects was 5.62, a high category. The group of subjects with the CC genotype had a higher DMF-T index (7.08; very high) than the group of subjects with the CT genotype (6.05; high) and TT (5.38; high). CT and TT genotypes with high risk were significantly lower than those with low-moderate caries risk. Conclusion: there is no significant association between the TAS1R2 gene polymorphism rs35874116 with the caries index value in the people in South Tangerang.
Study of 22 Children Friendly Public Health Center Bekasi City 2020 Mas Wishnuwardhana; Kevin Christian Sembiring; Vania Novita; Ivana Ester; Joue Abraham Trixie; Benedikta Suryandari
The Avicenna Medical Journal Vol 3, No 2 (2022)
Publisher : Faculty of Medicine, UIN (State Islamic University) Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v3i2.28980

Abstract

Background: Indonesia has a target to achieve Indonesia Layak Anak (IDOLA) predicate by 2030. Public health center has a very important role in realizing this target because public health center are the front guard for child protection in the health sector. This study aimed to know the overview of evaluation on the assessment of Children Friendly Public Health Center for the preparation of Indonesia Layak Anak 2030.Method: This type of this research is descriptive study. This report was conducted on the assessment of 22 Children Friendly Public Health Center on Bekasi city. The data was collected from the assessment and represented using Microsoft excel 2019.Results: Based on the total score obtained, the public health center with a total score of 965 was Karang Kitri Health Center, followed by Bojong Rawa Lumbu Health Center with a total score of  900 and Perumnas 2 Health Center with a total score of 89. There are still many public health center that do not meet the indicators and get maximum scores.Conclusion: This is the task of improving performance and facilities, to get maximum value and to be part of achieving the target for Indonesia as a Indonesia Layak Anak by 2030.

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