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LPPM Universitas Sari Mulia Gedung D Lantai 1 JL. Pramuka No. 02 Banjarmasin Kelurahan Pemurus Luar Kecamatan Banjarmasin Timur Kota Banjarmasin Kalimantan Selatan Indonesia
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INDONESIA
Journal of Pharmaceutical Care and Sciences
Published by Universitas Sari Mulia
ISSN : -     EISSN : 28284828     DOI : https://doi.org/10.33859/jpcs.
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Journal of Pharmaceutical Care and Sciences published by the LPPM Sari Mulia UniversityPharmacy department of Sari Mulia University offers a forum for publishing the original research related to pharmaceutical science and clinical research. our focus and scope are Pharmaceutical Technology, Pharmacology & Toxicology, Drug Delivery Development, Pharmacokinetic & Biopharmaceutics, Pharmacoeconomy, Pharmacoepidemiology, Pharmacovigilance, Clinical Pharmacy, Community Pharmacy, Chemical Pharmacy, and Chemical Analysis.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 162 Documents
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Narrative Review : Ekstrak Daun Bangkal (Nauclea subdita .Merr) Terhadap Paru-Paru Hewan Uji yang Terpapar Polusi Udara Akibat Kebakaran Hutan Shofi Maulana; Muhammad Rifqi Dharmawan; Wanda Nisa Pratiwi; Iwan Yuwindry
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 1 (2020): Journal Of Pharmaceutical Care and Science
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (327.688 KB)

Abstract

Forest fires occur almost every year in Indonesia, especially during the extreme dry season. Forest fires were anticipated in advance, but fires also continued. Haze from forest fires causes disturbances which cause health problems in the community, especially respiratory problems as a result. The main objective of this review article is to determine the efficacy of extracts of bangkal leaf (Nauclea subdita .Merr) as a treatment for Acute Respiratory Infection (ARI), so that it can support the government in reducing the incidence of Acute Respiratory Tract Infection (ISPA) due to forest fires. The method used in writing this article is Narrative Review, which is a literature search both nationally and internationally through indexed journal sites such as PubMed and Google Scholar. The results obtained after reviewing the article show that the extract of bangkal leaf (Nauclea subdita .Merr) can be efficacious as Treatment of Acute Respiratory Infection (ARI) because it contains flavonoids which can be used as antioxidants. The conclusion of the review article conducted by researchers about forest fires which can cause problems in the respiratory tract can be overcome with leaf extract (Nauclea subdita .Merr) as a natural treatment to treat Acute Respiratory Infection (ARI).
POTENSI EKSTRAK DAUN KETEPENG CINA (CASSIA ALATA L.) TERHADAP PENURUNAN KOLESTEROL DARAH MENCIT JANTAN HIPERLIPIDEMIA Nadia Nadia Chitania; Tuti Alawiyah; Alifira Adhany Yustian; Maria Dwi Ayu Listiawati
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 1 (2020): Journal Of Pharmaceutical Care and Science
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (367.427 KB)

Abstract

Cholesterol is an essential material to synthesize important substances in the body. Cholesterol is transported to various body tissues with the help of lipoprotein, which contain particles of fats, proteins and other substances. Hyperlipidemia is an increased level of lipids in the blood. Increased cholesterol levels occur mainly because of bad lifestyle; the habit of eating fast food or instant food which increasing cholesterol levels in the blood. Non-pharmacogical managements can be given by administering extracts of natural ingredients such as flavonoids contained in Ketepeng Cina. The aim of this study is to know the potential of ethanolic extract Ketepeng Cina Leaves to reduce plasma cholesterol in hyperlipidemic male mice. Analyzing through the database, Pubmed, Google Scholar from 2010 to 2020 with the keyword of Chinese patty, and flavonoids. 3 database search methods found 205 articles consisting of 24 google scholar, pubmed 169, and obtained 9 articles that filled the inclusion and exclusion criteria. The potential of ethanolic extract Ketepeng Cina Leaves (Cassia Alata L.) is proven to contain flavonoids that can reduce high number of cholesterol values in the blood of test animals such as mice
Analisis Kandungan Logam Berat Pada Krim Pemutih di Kota Banjarmasin I Ketut Gunawan Kusuma; Nur Hidayah; Tuti Alawiyah
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.104 KB) | DOI: 10.33859/jpcs.v2i1.66

Abstract

Background Whitening cream is a mixture of chemicals or other material which is able to whiten the skin. The presence of heavy metals such as Hg and Cd in the whitening cream products are very dangerous, because if the heavy metal ions adsorbed into tissue and organs, it will cause health problems. Objective This study aims was to find out the properties and levels of heavy metals mercuri and cadmium in the sample of the bleach cream in Banjarmasin. And to find out whether heavy metals in mercury and cadmium exceed the statute limit by the National Agency of Drug and Food Control of the Republic of Indonesia BPOM RI No. 12 tahun 2019. Method The study USES a method of analytic observation with a cross sectional design. The sample of the bleach cream used was a cream-bleach product with no license of The food and drug administration. As many as five samples of bleach cream were purchased at random in three markets that were on Banjarmasin analyzed using atomic absorption spectrophotometer. Results Research shows the highest hg concentration of metal showing on a sample of bleaching cream with a code E 0.675 µ /kg, the highest cd-metal content showing on the sample of the bleach code C 0.994 mg/kg. Conclusion: The result is under the limit set by the terms by the National Agency of Drug and Food Control of the Republic of Indonesia BPOM RI No. 12 tahun 2019. Keyword: Atomic Absorption Spectrophotometer, Heavy Metal, Whitening Cream
Aktivitas Antioksidan Dari Infusa Kelakai (Stenochlaena palustris (Burm.F) Bedd) Ali Rakhman Hakim; Amanda Shelvia Savitri; Rina Saputri
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.806 KB) | DOI: 10.33859/jpcs.v2i1.69

Abstract

Background: Kelakai (Stenochlaena palustris (Burn. F) Bedd.) Is a plant originating from Kalimantan that grows on peat soil. Objective: to determine the antioxidant activity of the leaves of kelakai (Stenochlaena palustris (Burm. F) Bedd.) made by infusion. Method: This type of research is true experimental and research method with post test only control group design. Kelakai made an infusion and then tested for antioxidant activity using the DPPH method. Results: The kelakai infusion positive contains flavonoids. Kelakai infusion has a very strong antioxidant activity at a concentration of 20 ppm with an absorbance value of 0.072 and an antioxidant activity of 86.90%. Kelakai infusion has an IC50 value of 6.4035 ppm. Conclusion: kelakai infusion positive contains flavonoid compounds and has a very strong antioxidant ability with an IC50 value of 6.4035 ppm. Keywords: antioxidants, flavonoids, infusion, kelakai
Studi Rasionalitas Penggunaan Antibiotika di RSUD DR. Murjani Sampit darini kurniawati
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.765 KB) | DOI: 10.33859/jpcs.v2i1.70

Abstract

Background Antibiotics are the most widely used type of drug due to the high incidence of infection in Indonesia. From the results of the preliminary study for 3 days prospectively, as many as 44 patients who received treatment, 37 patients (87%) received antibiotic therapy. There is the use of expensive antibiotics from the 3rd generation cephalosporin group, there are 4 trade names, 2 generation cephalosporins and 1 there are 6 trade names. Expensive sulbenicin and aminoglycoside derivatives are also found, Gentamicin and Kanamycin. The relatively cheap antibiotics are chloramphenicol, tetracycline, cotrimoxazole, but various brands of these products are popular with "me too drug" being used, of course with varying prices. Government Hospital type C should refer to the use of generic drugs and refer to the national antibiotic use guidelines. Therefore, researchers want to investigate further. Objective To study the patterns of antibiotic use at the Dr Murjani Sampit Regional Hospital before and after the Educational Information Communication on Guidelines for the Use of National Antibiotics. Method This study used a retospective and prospective descriptive observational study with pre-research intervention to medical personnel on the Guidelines for the Use of National Antibiotics and Rational Pharmacotherapy, to paramedics on the stability and method of administering injection dosage antibiotics. This retrospective study used medical documents for patients at 3 months intervals from inpatients for Surgery, Internal Medicine, Children and Gynecology. Prospective study of inpatients at the UPF Surgery, Internal Medicine, Children, and Gynecology for 1 week. Analysis of antibiotic prescribing patterns and the rationality of using antibiotics based on the National Antibiotic Guidelines and Use references. Results The distribution pattern of antibiotic use from a retrospective study of 447 patients, there were 260 (58.1%) patients using antibiotics. Even in obstetrics UPF, 100% of the gynecologists used antibiotics. The results of a retrospective study on the rational category and the cost of using antibiotics found the rationality of the indications and patients only reached <50% of the 4 UPFs studied. The rationality of the dosage regimen was <20% and the dose regimen <10%. Average cost of antibiotics wasted Rp. 80,374 per patient. The highest wastage was at UPF Obstetrics and Gynecology of Rp. 145,223/patient, while the lowest was in UPF Children of Rp. 40,837,-/ patient. From the prospective study, there were 260 patients, 100% used antibiotics with the rationality of the indications and the patients <50%, the rationality of the drug selection was <20%, the rationality of the dosage regimen was <10%. The average wasted cost of antibiotics which became a burden for patients was Rp. 74,793,-/patient with the highest waste at the UPF Gynecology Rp. 119,272,-/patient and the lowest in UPF Children was Rp. 34,697,-/patient. Conclusion The pattern of antibiotic use in Dr Murjani Sampit Hospital in the 4 UPFs studied was 49.1 - 100%. There was an irrational use of antibiotics, the right indication was <43%, the right drug selection was <37.7%, the right dose regimen was <20.8%, there was a combination of antibiotic interactions <6.9% and there was a waste from the use of antibiotics Rp. 80,374,-/patient in retrospective and Rp. 74,793,-/patient in the prospective study. Keywords Rationality, Antibiotics
Profil Penggunaan Antibiotika di Puskesmas Hantakan dan Profil DAGUSIBU Antibiotika di Desa Hantakan dan Desa Alat Rina Saputri; Ali Rakhman Hakim
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.132 KB) | DOI: 10.33859/jpcs.v2i1.71

Abstract

Background : The used of antibiotics in Indonesia continues to increase, but not accompanied by good knowledge regarding the used of these antibiotics so that they have a high risk of causing antibiotic resistance. Objective : Knowing the profile of the use of Antibiotics in Puskesmas Hantakan and knowing the profile of DAGUSIBU antibiotics in Hantakan and Alat Villages. Method : This type of research is descriptive research with survey methods for the last 5 months from October 2020 to February 2021. The survey was also carried out directly to the respondents of the Hantakan Village RT.01 - RT.06 and in Village Alat RT.01 - RT.04. Results : The used of antibiotics at Puskesmas Hantakan is one of the top 10 drugs that are often prescribed. The type of antibiotic that is most widely prescribed is Amoxicillin. DAGUSIBU's profile on respondents shows that the majority of respondents get antibiotics from stalls, use antibiotics to treat various diseases, take antibiotics not according to intervals, stop antibiotics if they feel that conditions have improved, and still keep antibiotics in stock and dispose of antibiotics in an inappropriate way. Conclusion : Amoxicillin is a type of antibiotic that is most widely prescribed in Puskesmas Hantakan. The use of antibiotics without a doctor's prescription in Hantakan and Alat Villages is still high. The proper management of antibiotics among respondents in the Village of Hantakan and Alat was still low.
PENGOBATAN TERKINI DAN PROFILAKSIS PRIMER PADA TOKSOPLASMOSIS Reqgi First Trasia
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (238.556 KB) | DOI: 10.33859/jpcs.v2i1.73

Abstract

Background: Toxoplasmosis is still a health problem in the world. This parasite is found cosmopolitan in humans and animals. In Indonesia, the prevalence of positive anti-Toxoplasma gondii substances in humans ranges from 2-63%, but there are still few comprehensive studies on current treatment and prophylaxis to treat it. Objective: This article will provide an in-depth review of current treatment and primary prophylaxis in toxoplasmosis. Methods: Searching the latest literature, obtained 10 relevant journals. Results: Initial therapy Pyrimethamine 200 mg was given for 6 weeks. Maintenance therapy (suppressive, secondary prophylaxis) is given for life if immune reconstitution does not occur. Primary prophylaxis against toxoplasmic encephalitis is given to patients who are seropositive for Toxoplasma. Conclusion: Initial therapy, maintenance, and primary prophylaxis can be useful to prevent worsening of the prognosis of toxoplasmosis disease.
The Potential Content of Karamunting (Rhodomyrtus tomentosa) in Binding With HMG-CoA Reductase Kunti - Nastiti; Samsul Hadi
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (368.962 KB) | DOI: 10.33859/jpcs.v2i1.76

Abstract

Background : Hyperlipidemia is the medical term for abnormally high levels of fats (lipids) in the blood. The two types of lipids found in the blood are triglycerides and cholesterol. The enzyme that plays a role in cholesterol regulation is HMG-CoA reductase. Objective : The purpose of this study was to find the content of karamunting compounds that have stability in interactions with HMG-CoA reductase. Method : The research method is to see the probability of activity with webservices, protein-compound interactions with PLANTS, visualization with Discovery studio. Results : The results of this study have a minimum activity probability of 0.5, namely -tocopherol-quinone, naringenin, quercetin, -tocopherol A, verimol K. The docking score is at least 80% against the reference ligand, namely -tocopherol-quinone (100%), blumeatin (82%), rhodomyrtosone C (80%), tetrahydroxyflavanone (81%), -tocopherol A (86%). Conclusion: The conclusion of this study is the probability of activity of the most potent compound is -tocopherol A and the interaction stability result is -tocopherol-quinone.
Analisis Pewarna Rhodamin B dan Pengawet Asam Benzoat dalam Saus Tomat di Kota Banjarmasin tuti alawiyah; Rahmadani Rahmadani
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (328.779 KB) | DOI: 10.33859/jpcs.v2i1.77

Abstract

Latar Belakang: . Saus tomat dengan warna yang merah seringkali disalahgunakan oleh produsen dengan menambahkan bahan pewarna yang dilarang penggunaannya pada makanan seperti Rhodamin B. Saus tomat juga biasanya dibuat dengan menambahkan bahan pengawet seperti Asam Benzoat yang tidak dapat terdisosiasi sehingga menimbulkan efek racun pada pemakaian berlebih Tujuan: untuk menganalisis bahan pewarna dan bahan pengawet dari segi analisis kualitatif serta analisis kuantitatif dalam beberapa produk saos tomat yang beredar di Kota Banjarmasin. Metode: metode penelitian adalah diskripsi analitik dengan mengidenftikasi senyawa rhodamin b menggunakan menggunakan Kromatografi Lapis Tipis dan Spektrofotometri UV-VIS dengan panjang gelombang 534 nm pada sampel saos A dan B, kemudian identifikasi senyawa Asam Benzoate dilakukan dengan analisis kualitatif yaitu uji warna dengan pereaksi FeCl3, titrasi asam basa serta metode spektrofotometri UV-VIS dengan panjang gelombang 230 nm. Hasil: metode KLT pelarut yang digunakan dengan menggunakan pelarut butanol: etil asetat: ammonia dengan perbandingan 10:4:5) Hasil menunjukkan bahwa nilai Rf untuk sampel 1 dan sampel 2 yaitu mendapatkan hasil 0,9966 cm. Hasil analisis kuantitatif rhodami b menggunakan metode spektrofotometer UV-VIS dengan panjang gelombang 543 nm Regresi kurva kalibrasi yang diperoleh persamaan garis y = 0.02265 x + 0,0226 dengan koefisien korelasi (r) sebesar 0,998330, rata – rata sampel 5,371 Simpulan: hasil identifikasi pada Rhodamin B tidak memenuhi syarat ketentuan permenkes, sedangkan hasil asam benzoat masih memenuhi standar SNI
Evaluasi Penanganan Nyeri Haid (Dysmenorrhea) Dengan Protection Motivation Theory Tasya Haditya; Mardlatillah Mardlatillah; Farah Nur Ain; Nur Syifa; Muhammad Akhzani Fadhli
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 2 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (384.835 KB) | DOI: 10.33859/jpcs.v2i2.80

Abstract

Background: Menstruation, known as menstruation or menstruation, is a physiological change in women that occurs periodically and is influenced by reproductive hormones, starting from menarche to menopause (Syafrudin, 2011). Abnormalities or disorders related to menstruation include premenstrual tension (tension before menstruation), mastodynia (pain in the breasts), mittelschmerz (pain during ovulation), and dysmenorrhea (pain during menstruation). Menstrual pain (dysmenorrhea) is one of the disorders that causes young women to go to the doctor for consultation and treatment. Menstrual pain or called Dysmenorrhea is pain that usually arises in adolescence, which is about 2 to 3 years after the first menstruation. Menstrual pain is a complaint that is often experienced by adolescents in the lower abdomen (Kusmiran, 2013). Menstrual pain makes women unable to carry out their normal activities and requires prescription drugs. This situation causes a decrease in the quality of life of women, for example female students who experience primary menstrual pain cannot concentrate on learning and learning motivation decreases because of the pain they feel. Objective: To see and evaluate the behavior of sufferers of menstrual pain (dysmenorrhea) in carrying out protective behavior (protection motivation theory) Methods: An evaluative study that aims to see the rationale for handling menstrual pain (dysmenorrhea) in students of the Faculty of Health, Sari Mulia University, Banjarmasin. The approach used in this research design is a cross sectional study where data is collected at a certain time. Data collection was carried out at the Faculty of Health, Sari Mulia University, Banjarmasin in April-May 2021. Results: In this project, research has been carried out on the Evaluation of Menstrual Pain Management (Dysmenorrhea) with the Protection Motivation Theory. We distributed 21 questions and got 80 respondents from various departments and semesters in the health faculty, namely 51.2% pharmacy students, 28.7% nursing students, 13.7% midwifery students and 6.3% health promotion students. The 80 respondents also consisted of 52.5% 4th semester students, 31.3% 2nd semester students, 12.5% 6th semester students and 3.7% 8th semester students. The age range of the respondents was 18-22 years old. Conclusion: Respondents make efforts to protect themselves from menstrual pain (dysmenorrhea) that is felt by doing therapy, both pharmacologically and non-pharmacologically. Respondents try to do rational treatment such as using the right dose, frequency, and proper use.

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