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LPPM Universitas Sari Mulia Gedung D Lantai 1 JL. Pramuka No. 02 Banjarmasin Kelurahan Pemurus Luar Kecamatan Banjarmasin Timur Kota Banjarmasin Kalimantan Selatan Indonesia
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Journal of Pharmaceutical Care and Sciences
Published by Universitas Sari Mulia
ISSN : -     EISSN : 28284828     DOI : https://doi.org/10.33859/jpcs.
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Journal of Pharmaceutical Care and Sciences published by the LPPM Sari Mulia UniversityPharmacy department of Sari Mulia University offers a forum for publishing the original research related to pharmaceutical science and clinical research. our focus and scope are Pharmaceutical Technology, Pharmacology & Toxicology, Drug Delivery Development, Pharmacokinetic & Biopharmaceutics, Pharmacoeconomy, Pharmacoepidemiology, Pharmacovigilance, Clinical Pharmacy, Community Pharmacy, Chemical Pharmacy, and Chemical Analysis.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 180 Documents
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Formulasi dan Evaluasi Sediaan Nano-Gel Minyak Atsiri Daun Nilam (Patchouli oil) Menggunakan HPMC Sebagai Gelling Agent Marhammah, Natasya Putri; Maharini, Indri; Elisma, Elisma; Rabbani, Haiga Hatthaya; Saputri, Sindi; Mulia, Zulaikha Permata; Afriana, Nadila
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.738

Abstract

Background: Acne vulgaris is a chronic inflammation of the pilosebaceous unit characterized by clinical signs of non-inflammatory and inflammatory lesions with varying degrees of inflammation, often caused by bacterial infection. Patchouli plant (Pogostemon cablin Benth) is a notable source of essential oil with antibacterial properties. Enhancing the effectiveness of essential oil as an anti-acne agent can be achieved through the development of a nanogel formulation.Objective: To formulate a nanogel containing patchouli leaf essential oil and evaluate its activity against Propionibacterium acnes.Methods: The formulation of patchouli leaf essential oil nanoemulsion was carried out with varying concentrations of patchouli oil at 1.5%, 2%, and 2.5%. The evaluation of the nanoemulsion included particle size analysis, zeta potential testing, and emulsion type determination. The resulting nanoemulsion was then formulated into a nanogel using HPMC as the gelling agent. The physical evaluation of the nanogel included organoleptic tests, homogeneity tests, viscosity tests, pH measurement, spreadability tests, adhesion tests, stability tests, irritation tests, and antibacterial activity tests. Data analysis was performed descriptively, followed by statistical analysis using One-Way ANOVA with a 95% confidence levelResults: The patchouli leaf essential oil (Patchouli Oil) nanoemulsion with concentrations of 1.5%, 2%, and 2.5% met the criteria for nanoemulsion formulation. The nanogel preparations in F1, F2, and F3 were solid in form, yellowish-white in color, had the characteristic aroma of patchouli leaf essential oil, and were homogeneous, meeting the requirements for gel formulations and stable. Conclusion: The formulation of nanogel containing patchouli leaf essential oil (Patchouli Oil) meets the requirements for a good gel preparation.  
F Formulasi Dan Evaluasi Sediaan Serum Gel Ekstrak Gliserin Bunga Asoka (Ixora coccinea L.) Rianti, Nur Addina; Audina, Mia; Muzdalifah, Nur; Ramadhan, Novalina Rossa; Donaretsi, Olga Nathania; Laili, Rofiatul
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.780

Abstract

Background:  The most common causes of skin dryness and redness are free radicals, pollution and ultraviolet rays. Cosmetics are epidermal treatments to nourish the body. One of the emerging cosmetics is a serum gel preparation that can maintain elasticity and moisturize the skin. While one of the plants has the potential to be used as a safe active ingredient in cosmetics, namely the asoka flower plant (Ixora coccinea L.) which is rich in phytochemical compounds, such as flavonoids, saponins, tannins, alkaloids, glycosides, terpenoids and carbohydrates, so it has very strong antioxidant activity. Objective:  To determine the appropriate formulation of asoka flower extract serum gel preparation and the effect of varying the concentration of asoka flower glycerin extract on the physical evaluation of serum gel preparation. Methods: This study used an experimental approach method with a true experimental design. The serum gel preparation was divided into 2 treatments with 15% and 30% concentration of active ingredients. The optimal formulation of the preparation is adjusted to the evaluation results and requirements set. Results:  Formula I met the organoleptical evaluation criteria, pH, flow type, and adhesion, but did not meet the specifications for viscosity and spreadability. While formula II meets the specifications of organoleptical test, pH, viscosity, flow type, adhesion, and spreadability. Conclusion:  From the evaluation conducted, it was found that the most optimal formula was formula II with 30% extract concentration.  Based on statistical tests using the Mann-Whitney Test, there is no effect on variations in the concentration of asoka flower extract.
Identifikasi Kandungan Rhodamin B Pada Blush On Dengan Metode Analisis Kualitatif Dan Kuantitatif Menggunakan Spektrofotometri Uv-Vis Amanah, Nurul; Raihanah, Raihanah; Adellia, Ocvrisia; Ardisya, Pinky Alifanda; Elliza, Putri; Pratama, Rahmad; Oktavia, Regina
Jurnal Pelayanan Kefarmasian dan Sains Vol 6 No 1 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v6i1.571

Abstract

Background: Cosmetics are one of the basic necessities for mankind, especially for women. Where its presence is very necessary for many women to beautify themselves and enhance their appearance. Objective: to find out whether the blush on the market in South Kalimantan uses Rhodamine B dye Method: qualitative analysis was carried out using staining, then continued with quantitative analysis using UV-Vis spectrophotometry Results: The quantitative results obtained for sample A were 18,699mg/L, for sample B 1,942 mg/L. Conclusion: From the results of quantitative and qualitative tests, it was found that sample A was positive for containing rhodamine B and sample B was negative for containing rhodamine B. From these results, sample A was declared very dangerous for consumers because it contained textile dyes. The greater the possibility that rhodamine B entering the body will have toxic effects, respiratory problems and skin disorders. Keywords: Rhodamine B, Blush On, Cosmetics.  
Formulasi Dan Evaluasi Sediaan Lulur Ekstrak Kayu Manis (Cinnamomum burmani) Dengan Variasi Konsentrasi Trietanolamin Rahmawati, Sinta; Budi, Setia; Rohama, Rohama; Audina, Mia
Jurnal Pelayanan Kefarmasian dan Sains Vol 6 No 1 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v6i1.728

Abstract

Background: Scrubs are extracts of natural ingredients from plants made in the form of scrubs used for beauty. One of the natural ingredients known to have proven efficacy as an antioxidant is Black Cumin (Nigella sativa L.) and cinnamon (Cinnamomum burmani). Black Cumin (Nigella sativa L.) contains unsaturated essential fatty acids (linoleic acid and linolenic acid) that function to rejuvenate skin cells and delay the aging process. Objective: Knowing the evaluation of physical quality and the effect of variations in emulgator concentration on the preparation of cream scrubs from black cumin (Nigella sativa L.) combined with cinnamon extract (Cinnamomum burmani). Methods: This research method uses true experimental. Cinnamon extract (Cinnamomum burmani) and black cumin flour (Nigella sativa L.) were made into cream scrub preparations with varying concentrations of triethanolamine. Results: The results showed that the preparation of black cumin (Nigella sativa L.) cream scrub combined with cinnamon extract (Cinnamomum burmani) with varying concentrations of triethanolamine met the organoleptic parameters, homogeneity, pH test and viscosity test but did not meet the parameters of the spreadability test. The concentration variation in each formulation has a difference in the pH test (0.027), viscosity (0.022) and has no difference in spreadability (0.365). Conclusion: Based of the three formulas of black cumin cream scrub with cinnamon extract with varying concentrations of triethanolamine have not met the physical quality evaluation and thus do not show a good variation of emulgator concentration.
Uji Aktivitas Antibakteri Ekstrak Kulit Jeruk Kalamansi (Citrofortunella microcarpa bunge) Pada Bakteri Propionibacterium Acnes Saputri, Nur Arida; Darsono, Putri Vidiasari; Mahdiyah, Dede; Audina, Mia
Jurnal Pelayanan Kefarmasian dan Sains Vol 6 No 1 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v6i1.734

Abstract

Background: Acne or acne vulgaris is an inflammatory disease that often occurs in the facial area. Usually characterized by the appearance of small reddish or yellow lumps (because they contain pus). The main organism that causes acne is Propionibacterium acnes. The growth of Propionibacterium acne bacteria can be controlled with antibacterials and plants that contain secondary metabolite compounds including flavonoids, alkaloids, saponins, steroids and tannins. One of the plants that contains secondary metabolites is calamansi orange peel. Objective: This study aims to determine the antibacterial activity of calamansi orange peel extract (Citrofortunella microcarpa Bunge) against Propionibacterium acnes bacteria through MIC and KBM testing. Method: This type of research is a true experimental method with post test only with control group design. Results: Antibacterial testing using the disc diffusion method on calamansi orange peel extract (Citrofortunella microcarpa Bunge) resulted in an inhibition zone of 22.02 mm, while MIC testing with concentrations of 5%, 7,5% and 10% resulted in inhibiting the growth of Propionibacterium acnes bacteria. while KBM did not produce results. The results of the Kruskal Wallis statistical test of 0.007 and Mann Whitney of 0.025 showed a p value <0.05, indicating that there was a significant difference between the extract concentration groups and there was a difference in the increase in the results of the bacterial activity test that received the extract treatment. Conclusion: Calamansi orange peel extract (Citrofortunella microcarpa Bunge) against Propionibacterium acnes bacteria has inhibitory power at concentrations of 50%, 75% and 100% but does not have killing power.  
Gambaran Pola Peresepan Dan Rasionalitas Terapi Pada Pasien Hipertensi Di Puskesmas Banjarbaru Selatan Periode Januari-Juni 2023 Indrawan, Dede; Yulistia Budianti; Aris Fadillah
Jurnal Pelayanan Kefarmasian dan Sains Vol 6 No 1 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v6i1.740

Abstract

Background:  Rational drug prescribing must follow a logical decision-making process starting from the collection of patient data through anamnesis, physical examination, laboratory tests, or other supporting examinations. The rational use of drugs in hypertension patients is very important to ensure cost-effectiveness, prescription accuracy, and drug use, as well as to improve the quality of healthcare services by evaluating indications, patients, drugs, and appropriate dosages. Objective: This study aims to understand the pattern of prescription and the rationality of therapy in hypertension patients at the Banjarbaru Selatan Health Center during the period of January - June 2023. Methods: This descriptive study uses a retrospective approach with the collection of secondary data from medical records, including age, gender, diagnosis, type of medication, medication class, medication category, indication, usage instructions, and dosage for hypertension patients over a period of 10 days. Results: The prescription pattern for patients based on drug class and type is the Calcium Channel Blockers (CCB) class and the amlodipine type at 95.7%. All hypertension patients received single antihypertensive drug therapy at 100%. Based on the usage rules and drug dosage, the type of drug amlodipine 1x1 was 51.60%. The rationality of antihypertensive therapy in the rational category was 98.39%, including 100% correct patients, 100% correct indication, 100% correct drug, 98.39% correct dosage, and 98.39% correct administration interval. Conclusion: The pattern of prescriptions based on drug class and type of drug used is the Calcium Channel Blockers (CCB) class and the type of drug amlodipine at 95.7%, and the depiction of the rationality of hypertension treatment therapy with a rationality of 98.39% at the Banjarbaru Selatan Health Center for the period January-June 2023.
Penentuan Nilai SPF (Sun Protection Factor) Ekstrak Metanol Buah Palem Merah (Crystotachys Renda Blume.) Sebagai Zat Aktif Tabir Surya Syamsurizal, Syamsurizal; Wahyu, Delma Aziza; Maharini, Indri
Jurnal Pelayanan Kefarmasian dan Sains Vol 6 No 1 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v6i1.765

Abstract

Background: Methanol extract from red palm fruit (Crystotachys renda Blume) contains secondary metabolites such as flavonoids, phenols, and tannins that have antioxidant properties. These compounds have the potential to act as sunscreen agents due to their ability to absorb UV-B radiation.Objective: This research aims to determine the Sun Protection Factor (SPF) value of methanol extract from red palm fruit as an active ingredient in sunscreen formulation. Method: This research began with the extraction process of red palm fruit simplicia using the maceration and reflux methods. The measurement of SPF values was conducted in vitro using UV-Vis Spectrophotometry at various concentrations, namely 100, 400, 600, 800, and 1000 ppm. Results: Based on the research findings, the methanol extract of red palm fruit has SPF values of 6.12; 24.43; 29.20; 30.67; and 31.00 at concentrations of 100, 400, 600, 800, and 1000 ppm, respectively. Conclusion: SPF testing shows that at a concentration of 1000 ppm, the methanol extract of red palm fruit has an SPF value of 31.00, which falls into the ultra protection category.      
Formulasi dan Uji Efektivitas Repellent Spray Gel Minyak Atsiri Daun Kayu Manis (Cinnamomum burmannii) Sebagai Penolak Nyamuk Syarli, Silviera; Elisma, Elisma; Lestari, Uce; Rahmadona, Tasha; Herawati, Ariana; Najwa, Shinta; Delfina, Rahmanda Ayu
Jurnal Pelayanan Kefarmasian dan Sains Vol 6 No 1 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v6i1.772

Abstract

Background:  Mosquitoes are insects that have the potential to be vectors or carriers of diseases to humans, including Dengue Fever (DBD), chikungunya, filariasis, and Japanese Encephalitis. Cinnamon leaves (Cinnamomum burmannii) are known to have eugenol compounds that can act as insecticides derived from natural ingredients. Objective: To determine the physical properties and effectiveness of cinnamon leaf essential oil against mosquitoes in the form of spray gel preparations. Methods:  The process of making spray gel preparations from Cinnamon Leaf Essential Oil uses variations in essential oil concentrations of 5%, 10%, and 15%. The base used as a gelling agent is Carbopol 940. Evaluation of the physical properties of the preparation includes organoleptic tests, homogeneity tests, pH tests, viscosity tests, spreadability tests, and adhesion tests. Result: The results of the study showed that differences in essential oil concentrations can affect the physical properties and effectiveness of spray gel preparations as mosquito repellents. Of the three formulas, F1 5%, F2 10%, and F3 15%, the best preparation is F2 with a concentration of Cinnamon Leaf Essential Oil (Cinnamomum burmannii) of 10% v/v. Conclusion:  The formula with the best results of physical properties and effectiveness were F2 with a concentration of 10%, which had an average protection power value of 82.4% with physical properties that met the requirements of a spray gel preparation.
Persepsi Masyarakat Mengenai Pencegahan DBD (Demam Berdarah Dengue) Di Wilayah Sungai Lulut Banjarmasin Berdasarkan Teori TPB (Theory Of Planned Behavior) Aisya, Rihaddatul; Melviani, Melviani; Komalia, Risyda
Jurnal Pelayanan Kefarmasian dan Sains Vol 6 No 1 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v6i1.793

Abstract

Background : Dengue Hemorrhagic Fever (DHF) is a disease that continues to increase from year to year very quickly. Prevention of dengue fever urgently requires the involvement of various elements, one of which is the community. Public perception of the prevention of Dengue Hemorrhagic Fever (DHF) can be analyzed based on the theory of Planned Behavior (TPB). Objective : To find out the perception of the community in the Lulut River Region regarding the prevention of Dengue Hemorrhagic Fever (DHF) based on the theory of Planned Behavior (TPB). Methods : Observational research analysis with cross sectional. Sampling was carried out by purposive sampling technique. The research sample amounted to 100 respondents. Data was obtained by questionnaires distributed to the community and analyzed by chi-square test. Results : 55% of the respondents had sufficient behavior, 46% of the respondents had a good attitude, 49% of the respondents had sufficient subjective norms, and 54% of the respondents had sufficient behavioral control. The attitude variable had a relationship with dengue prevention behavior of 0.014 (p<0.05), the norm variable had a relationship with dengue prevention behavior of 0.019 (p<0.05), the behavioral control variable had a relationship with dengue prevention behavior of 0.012 (p<0.05. Conclusion : The results of the test in this study showed that there was a relationship between attitudes, subjective norms and behavioral control with community behavior in the prevention of Dengue Hemorrhagic Fever (DHF) based on the Theory of Planned Behavior
Potensial Antibakteri Dari Tanaman Suku Anak Dalam (SAD) di Provinsi Jambi Lestari, Uce; Nalinda, Elba Annisa; Fitri, Khairunnisa Rizkia
Jurnal Pelayanan Kefarmasian dan Sains Vol 6 No 1 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v6i1.805

Abstract

Background: Bacterial infection is an event that is always a problem in the world of health. Bacterial infection can cause diseases such as diarrhea where the vector of transmission can be through the hands. Prevention can be done by maintaining hand hygiene, one of which is by using topical preparations that provide antibacterial activity made from natural ingredients, especially natural ingredients that are used by the Anak Dalam Tribe (SAD) in Jambi Province as medicine. Objective: To find out the potential of plants used by the Anak Dalam tribe in Jambi Province as antibacterials. Method: This study uses a systematic review method of the PRISMA method by searching for scientific publications in 2015-2025 based on the Crossref database. Results: The results obtained were endemic plants used by the Suku Anak Dalam (SAD) as medicine that have antibacterial activity against gram-positive and gram-negative bacteria such as S. aureus and E. Coli Conclusion: Plants that are often used by the Suku Anak Dalam as medicines have antibacterial abilities so that it can be proven that these plants have scientific evidence as antibacterials

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