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Agni Susanti
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Jurnal Neuroanestesi Indonesia
Published by Indonesian Society of Neuroanesthesia & Critical Care
ISSN : 20889674     EISSN : 24602302     DOI : https://doi.org/10.24244/jni
Core Subject : Health, Science, Education,
Biochemistry, Genetics & Molecular Biology Education Medicine & Pharmacology Neuroscience Public Health
Editor of the magazine Journal of Neuroanestesi Indonesia receives neuroscientific articles in the form of research reports, case reports, literature review, either clinically or to the biomolecular level, as well as letters to the editor. Manuscript under consideration that may be uploaded is a full text of article which has not been published in other national magazines. The manuscript which has been published in proceedings of scientific meetings is acceptable with written permission from the organizers. Our motto as written in orphanet: www.orpha.net is that medicine in progress, perhaps new knowledge, every patient is unique, perhaps the diagnostic is wrong, so that by reading JNI we will be faced with appropriate knowledge of the above motto. This journal is published every 4 months with 8-10 articles (February, June, October) by Indonesian Society of Neuroanesthesia & Critical Care (INA-SNACC). INA-SNACC is associtation of Neuroanesthesia Consultant Anesthesiology and Critical Care (SpAnKNA) and trainees who are following the NACC education. After becoming a Specialist Anesthesiology (SpAn), a SpAn will take another (two) years for NACC education and training in addition to learning from teachers in Indonesia KNA trainee receive education of teachers/ experts in the field of NACC from Singapore.
Arjuna Subject : Kedokteran - Anesthesiology and Pain Medicine
Articles 7 Documents
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Search results for , issue "Vol 13, No 1 (2024)" : 7 Documents clear
The Relationship of Cortisol Levels and Sleep Quality in Acute Ischemic Stroke Patients: A Literature Review Amalia, Lisda
Jurnal Neuroanestesi Indonesia Vol 13, No 1 (2024)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v13i1.533

Abstract

Hormonal factors are one of several elements that contribute to the process by which patients with acute ischemic stroke experience poor sleep quality. The hypothalamic-pituitary-adrenal (HPA) axis is responsible for producing the hormone cortisol. When the hypothalamus is activated, it releases vasopressin and Corticotropin Releasing Hormone (CRH), both of which influence Adrenocorticotropic Hormone (ACTH). This hormone triggers release of cortisol and other glucocorticoids by the adrenal glands. The HPA axis becomes engaged during an acute disease. Cortisol levels will rise as a result of HPA axis activation. Specifically, injury to the frontal or medial temporal lobes of the brain, as well as inflammation, or a lack of regulation of the HPA axis, can lead to this medical condition. Cortisol levels might remain elevated for up to seven days following the start of a stroke. An increase in cortisol levels is connected to an highly risk of stroke severity, length of hospital stay, and mortality in stroke patients. It is also an early warning sign of deteriorating sleep quality in patients with acute ischemic stroke.
Comparison of Changes in Cortisol Levels in the Blood of Patients Undergoing Craniotomy Using Continuous Infusion Lidocaine and Fentanyl Syaputra, Adhika; Irina, Rr Sinta; Lubis, Andriamuri Primaputra; Harahap, Juliandi
Jurnal Neuroanestesi Indonesia Vol 13, No 1 (2024)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v13i1.565

Abstract

Background and Objectives: Craniotomy is a surgical procedure that involves part of the skull, temporarily removing it to expose the brain and carrying out intracranial procedures. The surgery can be considered as the standard model for assessing cortisol as a stress response. Cortisol in the blood can cause hemodynamic and physiological changes in the body such as increased heart rate, increased blood pressure, and also increased blood sugar levels. Some literature showed that continuous infusion of fentanyl and lidocaine - has an effect in maintaining the responses to stress, namely the level of cortisol in the blood. The aim aimed to determine the comparison of changes in cortisol levels in the bloodpatients undergoing craniotomy using continuous infusion lidocaine and continuous infusion fentanyl.Subject and Method: This research used a double-blind randomized controlled trial (RCT) with a pre-test and post-test with a control group design. This study divided the samples into 2 groups. Continuous infusion of lidocaine and continuous infusion of fentanyl were then checked for cortisol levels in the patient's blood before and after undergoing craniotomy.Results: The result of 28 samples that underwent craniotomy, 6 samples were excluded, so the total number of samples analyzed was 22 samples. Differences in mean cortisol levels before and after surgery in the lidocaine and fentanyl groups were 193.90 nmol/L and 153.90 nmol/L respectively with a P value of 0.021.Conclusion: In the study, it was found that cortisol levels increased in both fentanyl and lidocaine groups after a craniotomy. There is a significant difference between the two groups of fentanyl and lidocaine, where statistically the fentanyl group was better at maintaining blood cortisol levels after craniotomy than the lidocaine group.
Neuroanesthesia Management in Cavernous Sinus Meningioma Craniotomy Patients Rozi, Fakhriyadi; Prihatno, MM Rudi; Cahyono, Iwan Dwi
Jurnal Neuroanestesi Indonesia Vol 13, No 1 (2024)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v13i1.583

Abstract

AbstractThe most prevalent primary cavernous sinus (CS) lesion is cavernous sinus meningioma (CSM). Of all intracranial neoplasms, 1% are tumors in CS, and 41% are CSM. For contemporary neurosurgeons, orbital involvement in cavernous sinus meningiomas (CSMs) poses special difficulties. The condition is known as cavernous sinus meningioma (CSM) gradually impairs vision and may ultimately result in chiastic compression. Since January 2023, a male 55-year-old had been admitted to the hospital with cephalgia and mild diplopia in his right eye. Cavernous meningiomas were discovered using CT scans, and a craniotomy procedure was scheduled to remove the tumor. In order to facilitate intubation, the patient was given a premedication of sufentanyl for analgesia and was then given general anesthesia. Rocuronium was used to relax the muscles. Desflurane is an attractive option available to anesthesiologists to maintain general anaesthesia. This surgical procedure of removing intracranial tumours requires proper induction and monitoring of the patient's condition during surgery to prevent increased intracranial pressure. Intracranial elevation can cause systemic changes such as hypertension and changes in heart rhythm, as well as cerebral artery spasm, and lead to cerebral infarction and cerebral ischemia. An effective neuroanesthesia management program can help preserve hemodynamic stability and improve results during craniotomy surgery for the removal of meningiomas.
Endotracheal Intubation without Neuromuscular Blocking Agent in Patient with Fracture Cervical Spine C1 and C4 Underwent Fusion C12 and C46 Suarjaya, I Putu Pramana; Purwanto, Osmond; Aldy, Aldy; J. Sutawan, Ida Bagus Krisna
Jurnal Neuroanestesi Indonesia Vol 13, No 1 (2024)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v13i1.584

Abstract

About 30% of cervical spine fractures involve injuries to the C1 and C2 vertebrae, which are considered unstable. Ensuring the stability of the injured cervical spine throughout perioperative period, including preoperative examinations, anesthesia induction, laryngoscopy, and intubation, is crucial for anesthesiologists. A 40-year-old woman suffered neck pain following a motorcycle accident, suffering a Spinal Cord Injury ASIA Impairment Scale (SCI AIS) E, a fracture of the C5 vertebral body (CV) classified as AO Spine Type A2, a Jefferson Type IV fracture, and mild head trauma. She underwent surgical fusion of the C1C2 and C4C6 vertebrae under general anesthesia, which included dexmedetomidine, propofol, sevoflurane, and fentanyl without any neuromuscular blocking agents (NMBA). The primary goal of perioperative airway management in cervical injury is a secured airway, while maintaining cervical stability without inflicting secondary injury. The cervical muscle group is essential for maintaining cervical stability, and the use of NMBA may jeopardize this stability, necessitating external cervical stabilization, especially during laryngoscopy and intubation. Induction agents in combination with opioid, widely used to facilitate laryngoscopy and intubation without using NMBA. Anesthesiologists must precisely arrange the management of cervical spine injuries patient to avoid secondary injury and improve surgical outcomes.
Anesthesia Management for Evacuation of Cerebral Abscess in Geriatric Patient with Myasthenia Gravis Suarjaya, I Putu Pramana; Purwanto, Osmond; Wundiawan, Kristian Felix; J. Sutawan, Ida Bagus Krisna
Jurnal Neuroanestesi Indonesia Vol 13, No 1 (2024)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v13i1.585

Abstract

A Cerebral abscess is an intracranial focal abscess which is a life-threatening emergency. Myasthenia gravis is an autoimmune disorder caused by antibodies targeting the neuromuscular junctions post-synaptic receptor. A seventy-three-year-old male, with an intra-axial tumor in the frontoparietal region underwent craniotomy for abscess evacuation. The Patient also has a history of hypertension and myasthenia gravis under treatment of dexamethasone and pyridostigmine. Anesthesia induction was performed with thiopental, opioid analgesics with fentanyl, neuromuscular blocking agent (NMBA) with rocuronium, and scalp block. The Patients depth of neuromuscular block was monitored with a Train-of-Four (TOF). Surgery was performed in a supine position, duration of surgery was 4.5 hours. The Patient was extubated in the operating theatre, monitored in the intensive care unit, and discharged home on the nineteenth day. Anesthetic management in geriatric patients with cerebral abscesses accompanied by myasthenia gravis has become complex due to the interaction of disease state, medical treatment, anesthetic drugs especially neuromuscular blocking agents, and surgical stress. The Patient was at risk for residual paralysis and had high sensitivity to nondepolarizing neuromuscular blocking agents, so the use of train-of-four (TOF) was very helpful for extubating this patient safely.
Perioperative Management Patients with Meningioma C1-2 Bisri, Dewi Yulianti; Indrayani, Ratih Rizki; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 13, No 1 (2024)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v13i1.587

Abstract

Removal of spinal meningiomas in cervical 1 and 2 has several problems, especially regarding the respiratory and cardiovascular systems. A woman, 33 years old, admit Santosa Bandung Central Hospital with complaints of weakness in her left hand and both legs since 4 months ago. Weight 50 kg, height 155 cm, blood pressure 146/102 mmHg, pulse rate 105 x/min, temperature 36.50C, SpO2 98% with room air. At diagnosis of cervical myelopathy due to space occupying lesion (SOL) intradural meningioma suspect. Induction of anesthesia with fentanyl 100 mcg, propofol 60 mg, rocuronium 40 mg, ventilated with 100% oxygen and sevoflurane 3 vol% (1.5 MAC), before laryngoscopy-intubation repeated half the initial dose of propofol. The patient is intubated in an in-line position. Anesthesia maintenance with sevoflurane 1 vol%, oxygen: air 50%, dexmedetomidine continuous 0.4 mcg/kg per hour, and continuous rocuronium 10 mcg/kgBW/min. Ventilation is controlled with a tidal volume of 360 ml, frequency 14 times/min. Then the patient is positioned in the prone position. Post-surgery is admitted to the ICU and day 5 the patient can be discharged from the hospital. The effects of C12 spinal cord tumors can affect the respiratory and cardiovascular systems. Surgical trauma can aggravate the injury before recovery occurs, so it is necessary to do ventilation assistance and cardiovascular support before recovery.
Prognosis of Surgical Management for Intracerebral Hemorrhage: Insights from Indonesia's National Brain Center Hospital Rahmatisa, Dimas; Lasanudin, Joshua Eldad Frederich
Jurnal Neuroanestesi Indonesia Vol 13, No 1 (2024)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v13i1.588

Abstract

Background and Objective: Intracerebral hemorrhage (ICH), a stroke subtype that can be managed surgically, exhibits varying prognoses amongst countries. However, data for the Indonesian population are currently lacking. Subject and Methods: In a retrospective cohort study, medical records of post-surgical ICH cases in Rumah Sakit Pusat Otak Nasional from January 2021 to April 2023 were obtained. Prognostic data includes hospitalization duration, in-hospital mortality, and dependency upon discharge. Multivariate analysis was performed on sociodemographic and medical data to determine prognostic factors.Results: A total of 157 cases were obtained. Procedures performed include hemorrhage evacuation craniotomies (58.6%), burr holes (29.9%), ventriculoperitoneal shunts (24.2%), and decompressive craniectomies (5,1%), with 15.9% patients undergoing multiple surgical sessions. In-hospital mortality and total dependency occurred in 31.2% and 54.6% of patients, respectively. Average hospitalization is 16.32 days. Predictors for in-hospital mortality are age ? 50 years (p=0.002), male (p=0.014), hematoma volume 40mL (p=0.012), multiple surgical sessions (p=0.034), and presenting Glasgow Coma Scale (GCS) 9 (p=0.015). Predictors for total dependency are supratentorial lesions (p=0.025) and presenting GCS 9-12 (p=0.008) and 9 (p=0.002). Predictors for hospitalization 2 weeks are stroke onset 3.5 hours (p=0.008) and multiple surgical sessions (p=0.001). Conclusion: Surgical management of ICH in Indonesia reveals similar outcomes to other countries. However, differences in prognostic factors indicate potential variations between countries.

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