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Khazanah: Jurnal Mahasiswa
Published by Universitas Islam Indonesia
ISSN : 1979519X     EISSN : 27458733     DOI : 10.20885/khazanah
Core Subject : Religion, Economy, Humanities, Health, Science, Education, Social, Engineering,
Religion Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences
“Khazanah: Jurnal Mahasiswa” merupakan platform publikasi jurnal yang mulai diresmikan pada tahun 2009. Jurnal Khazanah diterbitkan oleh Direktorat Pembinaan Kemahasiswaan (DPK) Universitas Islam Indonesia yang bekerjasama dengan Kelompok Studi Laboratorium Mahasiswa (LabMa) Universitas Islam Indonesia. Jurnal Khazanah telah terverifikasi pada Online Journal System (OJS) dibawah naungan jounal.uii.ac.id sejak tahun 2011. Jurnal Khazanah telah rutin menerbitkan jurnal dalam 1-2 edisi per tahun. Karya yang diterbitkan merupakan suatu hasil penelitian orisinil atau tinjauan Pustaka yang ditulis oleh mahasiswa. Ruang lingkup karya yang diterbitkan mencakup sains dan sosial.
Arjuna Subject : Umum - Umum
Articles 162 Documents
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ENDOPLASMIC RETICULUM STRESS PATHWAY AS TARGETING THERAPY IN NON COMMUNICABLE DISEASES: A NARRATIVE REVIEW Isniarta, Zhovarina
Khazanah: Jurnal Mahasiswa Vol. 13 No. 4 (2021): Abstract Proceeding Book: 2st International Conference-Labma Scientific Fair
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol13.iss4.art13

Abstract

Background: World Health Organization (WHO) declared that non-communicable diseases still become the main health problem by including it in goal 3.4 in sustainable development goals and also a major cause of mortality worldwide. Based on prevalence, mortality in non communicable diseases is dominated by cancer, cardiovascular disease, diabetes mellitus, and chronic lung disease. Although non-communicable diseases have complex mechanisms and signalling pathways, the role of endoplasmic reticulum stress has been known for its association with abnormal metabolism in non-communicable diseases. This narrative review aims to investigate targeting therapy in non-communicable diseases based on the endoplasmic reticulum stress pathway. Method: The literature search was carried out through several electronic databases (PubMed and Google Scholar), using keywords “endoplasmic reticulum stress”, “non-communicable disease”, “therapy”, “drugs”. Full English text publication between 2010 to 2021 was selected for identification. Result: The endoplasmic reticulum stress occurs due to adaptive and defensive response to lack of oxygen (hypoxia), hypoglycemia and hyperglycemia, hyperthermia, starvation, calcium imbalance, the redox milieu, and also the imbalance between oxidants and antioxidants. Those conditions can impact protein folding in endoplasmic reticulum stress cause accumulation of unfolded and/or misfolded protein that leads to activation of unfolded protein response (UPR). A number of studies in non-communicable diseases such as diabetes mellitus, cardiovascular disease, and cancer showing that some compounds can ameliorate endoplasmic reticulum stress by targeting the pathway. Conclusion: Targeting therapy in the endoplasmic reticulum pathway can be a novel strategy for the treatment of non-communicable diseases. Keywords: Endoplasmic reticulum stress, non-communicable disease, therapy.
BIOTECHNOLOGY OF TARO PRODUCTS THAT CONTAIN LOW GLYCEMIC INDEX TO BE SUBSTITUTE FOOD FOR PEOPLE WITH DIABETES Adhika, Hanan Nur
Khazanah: Jurnal Mahasiswa Vol. 13 No. 4 (2021): Abstract Proceeding Book: 2st International Conference-Labma Scientific Fair
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol13.iss4.art14

Abstract

Diabetes is a serious problem in Indonesia. Even people with diabetes increases every year. The latest data from the International Diabetes Federation (IDF) shows Indonesia is ranked seventh in the world with 10.7 million people with diabetes. This can be caused by consuming food without paying attention to the high glycemic index (GI) content in food ingredients. Therefore, foodstuffs containing a low glycemic index are needed and are usually found in tubers, especially taro. This study aims to determine the biotechnology of processed food from taro for diabetics. With the biotechnology of processed food products from taro, it helps diabetics to control their blood sugar. This research method is carried out by quantitative methods or based on previous research studies. Taro has a low glycemic index content so it can be consumed by diabetics. With a low GI content in taro it can control the increase of blood sugar levels. Taro can actually be processed into a more varied staple food. Taro can be made into cereals or flakes so it can make easier to consume. With biotechnology process of taro products, diabetics can more easily control blood sugar levels in the body because of its low glycemic index content. Keywords: Diabetes,taro,Glycemic.
POTENTION OF TANIN ENCAPSULATED DEXTRAN-MODIFIED-LIPOSOME AS PREVENTIVE AGENT OF DENTAL CARIES: A REVIEW Salsabila, Zavia Putri; Sugianto, Violetta Meitrie; Mudzkiroh, Fathiyatul
Khazanah: Jurnal Mahasiswa Vol. 13 No. 4 (2021): Abstract Proceeding Book: 2st International Conference-Labma Scientific Fair
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol13.iss4.art15

Abstract

Background: Caries is one of the most common diseases and affects people in the world. It is estimated that about 3.58 billion people in the world suffer from caries. The prevalence of the population with cavities / sick / damaged teeth in Indonesia in 2018 reached 45.3%. Caries is tooth enamel damage due to dysbiosis microbiome in the oral cavity. Caries is caused by the presence of Streptococcus mutans bacteria which form biofilm / plaque. The biofilm can reduce the remineralization ability of the teeth that tooth decay can occur. Until now, there is no preventive action that can prevent caries formation to the maximum. This article is designed to determine the potential of dextran-modified-liposome encapsulation against tannin as a preventive measure for dental caries. Methods: This article was created by searching multiple databases with the keywords caries, liposome, tannin, and dextran. Result: One of the preventive measures against dental caries is using tannin compounds. The main function of tannin is to significantly reduce the attachment of bacteria and form glucans to enamel, and bind to proteins in the mouth to inhibit bacterial metabolism. However, tannin have a disadvantage that bitter taste and easily bind to other macromolecules such as enzymes in the mouth. These deficiencies can be overcome by using liposome encapsulation. To increase the effectiveness of tannins in the process of targeting and preventing biofilms, liposome encapsulation was modified using dextrans. Dextrans can play a role in inhibiting sucrose dependent biofilms to prevent biofilms formation. Conclusion: Dextran-modified-liposome encapsulation against tannin has the potential to be an effective preventive measure against the development of dental caries. Keywords: Caries, liposome, tannin, dextran
THE RISE OF FAMILY VIOLENCE AND PARENTING STRESS DURING THE COVID-19 PANDEMI: FAMILY SCIENCE PROPOSED SOLUTIONS AND DIRECTION Mohammad Anggito Abimanyu; Muhammad Zudi Hardiansyah; Khalisa Hasanah Labay
Khazanah: Jurnal Mahasiswa Vol. 13 No. 4 (2021): Abstract Proceeding Book: 2st International Conference-Labma Scientific Fair
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol13.iss4.art4

Abstract

The rise of family-oriented misconduct is rising during the pandemic situation due to multiple problems related to economy, social and even many other physical embodiments in the element of living. In the theory of living substances, internal parental, external resources and parental perceptions towards all of the stressors element will impact how families cooperate with all of these burdens that they face, which may impact the possibility of child abuse, physical and mentally. This paper will uncover all of the available stressors that happen as a consequence of COVID-19 pandemic using the family stress theory at the family and society level, and then further elaborates how these elements are associated with family violence via parents perceptions and coping strategies. This research will also elaborate with the possible future obstacles that families may face during the implementation of new protocols, strict market revenue, and many other possible social barriers and obstacles ahead within the possible future change and development of society conditions. Keywords: Covid-19, family stress theory, child abuse risk, perception
FACTORS AFFECTING E-SCOOTER SHARING PURCHASE INTENTION TO COMBAT CLIMATE CHANGE: AN ANALYSIS USING UNIFIED THEORY OF ACCEPTANCE AND USE OF TECHNOLOGY Belinda Azzahra
Khazanah: Jurnal Mahasiswa Vol. 13 No. 4 (2021): Abstract Proceeding Book: 2st International Conference-Labma Scientific Fair
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol13.iss4.art20

Abstract

Transportation uses a significant amount of energy and burns most of the world's petroleum. As a result, it gives effect to the environment, such as air pollution in the forms of carbon dioxide, nitrous oxide, and particulates. Those compounds create a phenomenon called global warming. Within the transportation sector, road transport is the largest contributor to global warming. To cope with global warming, environmental regulations in developed countries are trying to reduce the individual vehicle's emissions. However, this has been counterbalanced by an increase in the number of vehicles and increased use of each vehicle. Therefore, micro-mobility may alleviate several challenges facing big cities today and offer more sustainable urban transportation. In the next ten years, e-scooter sharing is predicted to become an international business as its potential to become a multi-billion dollar industry (Purnomo Yusgiantoro, 2019). E-scooter sharing has seen a massive leap in popularity within the last few years because, on the surface, it appears to be a business model that is here to stay and, most importantly, has become a solution in creating a greener environment and economy. This research utilizes the framework of the UTAUT2 to identify and build a quantitative approach to identify factors related to the purchase intention factors of e-scooter sharing. The 200 respondents' field data were collected in Jakarta Metropolitan Area (Jabodetabek) as a rapid increase in pollution level and a considerable number of essentials of the central business district and many high-rises stores and universities. The linear regression study revealed that the consumers' purchase intention of e-scooter sharing is shaped by seven main factors: performance expectancy, effort expectancy, social influence, facilitating condition, hedonic motivation, price value, and habit. Those factors can explain 83 percent of the field data. Moreover, a brief recommendation for related stakeholders based on the Research results are proposed to increase the adoption of e-scooter sharing. The practical implications resulting from this analysis are suggested policy measures, e-scooter sharing, environmentally impact potency and strengthening green economy achievement in the communities. Keywords : E-Scooter Sharing, Green Economy, Linear Regression, Purchase Intention
INNOVATION OF BIODEGRADABLE MEMBRANE NANOFILTER MASK BASED ON CELLULOSE EMPTY PALM OIL BUNCHES AS A FUTURE MASK Thabed Tholib Baladraf
Khazanah: Jurnal Mahasiswa Vol. 13 No. 4 (2021): Abstract Proceeding Book: 2st International Conference-Labma Scientific Fair
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol13.iss4.art18

Abstract

Background: Covid-19 has become a public health emergency of international concern that is transmitted through respiratory droplets. Prevention is a very important things to maintain public health, one of which is by using masks. This raises new problems related to mask waste which is non-biodegradable. There needs to be a solution in the form of environmentally friendly masks that are easily biodegradable, one of which is by utilizing the cellulose content in empty palm oil bunches. The purpose of this study was to determine the process of making environmentally friendly masks from empty oil palm fruit bunches, to determine the thickness and biodegradation results of masks. Method: The method used in this research is experimental. In this study, the manufacture of nanofilters, thickness testing, and biodegradation tests were carried out. The process of making environmentally friendly masks from oil palm empty fruit bunches goes through four main stages, namely extraction of cellulose from the waste of oil palm empty fruit bunches, synthesis of cellulose acetate, manufacture of biodegradable nanofilter membranes, and finishing. Result: The results showed that the masks had a thickness of 0.79-0.97 mm and the results of biodegradation tests showed 2.7-7.03% results. These results show a very good indication that it has the potential to be used as an air mask that is feasible to use and environmentally friendly because it is easily biodegradable. Conclusion: The process of making environmentally friendly masks from oil palm empty fruit bunches goes through four main stages, namely extraction of cellulose from the waste of oil palm empty fruit bunches, synthesis of cellulose acetate, manufacture of biodegradable nanofilter membranes, and finishing. Thickness test results yield 0.79-0.97 mm and biodegradation test results show 2.7-7.03% results. Keywords: Biodegradation, Mask, Palm Oil Bunches
SEA AND COVID-19 VIRUS: (ANALYSIS EFFECT OF THE COVID-19 PANDEMIC ON MARINE ECOSYSTEM IN INDONESIA IN 2020-2021) Fadila Aulia
Khazanah: Jurnal Mahasiswa Vol. 13 No. 4 (2021): Abstract Proceeding Book: 2st International Conference-Labma Scientific Fair
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol13.iss4.art19

Abstract

Marine ecosystems are one of the most extensive and diverse biological natural resources. Unfortunately, at this time the marine ecosystem is starting to be threatened. According to preliminary calculations from the Coordinating Team for the National Secretariat for Handling Marine Debris, the total waste entering the sea in 2020 is estimated to reach 521,540 tons, of which around 12,785 tons originate from activities at sea. The purpose of this research is to see how the impact of the Covid-19 pandemic on marine ecosystems. Researchers want to see if the Covid-19 pandemic has a positive impact that can be used as a reference for improving a sustainable marine ecosystem. The method that the researcher uses in this research is the literature study method using previous research journals as a reference for data collection. Based on the literature study that has been carried out, the researchers obtained the results that the Covid-19 pandemic had positive and negative impacts on marine ecosystems. The positive impact caused is the reduction in human activities during the Covid 19 pandemic, making marine ecosystems have a high probability of recovering. While the negative impact is the increase in waste production. Because when the Covid-19 pandemic occurred, many people shopped through online applications. However, seeing that the restriction of human activity during the Covid-19 pandemic has a positive impact on marine ecosystems, this policy can be continued. By limiting visitors who come to marine tourism areas. For example, marine tourism is only opened 3 times a week and visitors who are allowed to come cannot be more than 30 people. This is expected to reduce marine pollution caused by human hands. Keywords : Covid-19 pandemic, marine ecosystem, pollution.
Utilization of Whey Dangke into High Quality Edible Film as a Solution for Environmental Pollution in Indonesia Putri Izzatul Aulia
Khazanah: Jurnal Mahasiswa Vol. 13 No. 4 (2021): Abstract Proceeding Book: 2st International Conference-Labma Scientific Fair
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol13.iss4.art16

Abstract

Today, the problems related to waste and waste are still unsolved. The National Plastic Action Partnership (NPAP) recorded that around 4.8 million tons of plastic waste in Indonesia is not managed properly. In addition, industrial waste such as whey has not been widely used so that it has a high potential to cause environmental pollution. For this reason, this research was carried out to overcome this problem by making edible films from whey dangke with the addition of carrageenan, 35% sorbitol plasticizer and red galangal (Alpinia purpurata) essential oil as quality enhancers. This research is expected to reduce plastic waste and industrial waste by utilizing dangke whey processed into environmentally friendly edible films. This study uses qualitative methods as material content analysis and quantitative in determining the concentration of quality enhancing ingredients. Dangke whey waste was chosen as the main ingredient of edible film because 80-90% of the milk volume is whey and contains about 55% of the total nutrition of milk. The addition of carrageenan is intended to reduce cracks because the surface is flat and to balance the flexibility, 35% sorbitol is added. To inhibit the activity of bacteria (E. coli and S. aureus) 0.1% red galangal essential oil (A. purpurata) was added. From here, edible films can be produced by using whey dangke waste which is bacteria resistant, minimally cracked, but still flexible and friendly to health.
Conversion Of GeNose C-19 Plastic Waste And HDPE (High Density Poly Ethylene) Into Alternative Energy Bio-Oil Using The Co-Pyrolysis Method Guntur Martha Baya; Indah Ika Nurcahyani; Ilya Marsya Rohila
Khazanah: Jurnal Mahasiswa Vol. 13 No. 4 (2021): Abstract Proceeding Book: 2st International Conference-Labma Scientific Fair
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol13.iss4.art17

Abstract

Background: Covid-19 has spread to various countries in the world, one of which is Indonesia. The positive cases until March 29, 2021, have reached one and a half million cases and still increasing. GeNose is the latest Covid-19 testing tool that is able to detect the presence of Covid-19 with a sensitivity level of 89-92% and a specification of 95-96%. The ease of using GeNose C-19 has increased so that GeNose C-19 plastic waste also increases. If this is not considered, it will cause a new problem, such as the accumulation of plastic waste caused by the use of the GeNose C-19 tool. Method: As solution to handling that problem, we utilize GeNose plastic waste with addition of HDPE (High Density Poly Ethylene) plastic to produce alternative bio-oil energy products. The methods used in this research are quantitative and qualitative methods with literature studies and research, where we collect data from various scientific journal including Garuda Ristekdikti, SINTA, and Google Scholar using the keywords GeNose waste, Pyrolysis, Plastic waste. In addition, we use the research process using a pyrolysis reactor. Result: The resulting liquid from pyrolysis method is in the form of bio oil which can be used as an alternative energy material. However, the bio oil produced from the pyrolysis process does not produce high quantitative results. So, we combine with HDPE plastic with a ratio of 1:1 (Co-Pyrolysis) to get better results quantitative or qualitative and also have a better indication. Conclusion: GeNose plastic waste treatment with the pyrolysis method with the addition of HDPE raw materials produces bio-oil products in larger quantities. In addition, the pyrolysis of GeNose plastic waste with the addition of HDPE, has a better and longer fuel power than bio oil from the pyrolysis of pure GeNose plastic waste. Keywords: Covid, GeNose, HDPE, Pyrolysis.
GIRIREJO VILLAGE MICRO SMALL AND MEDIUM ENTERPRISES EMPOWERMENT MODEL THROUGH THE WIRADESA ROGRAM Ahmad Nur Rohim; Shaffira Ayuning Byzhura; Dewi Anggraeni Sekarwati
Khazanah: Jurnal Mahasiswa Vol. 13 No. 4 (2021): Abstract Proceeding Book: 2st International Conference-Labma Scientific Fair
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/khazanah.vol13.iss4.art5

Abstract

Background: The Village Sustainable Development Goals (SDGs) are an integrated effort that includes 18 development goals in solving village’s problems. The SDGs are a real effort to accelerate sustainable development at the village level to create villages without poverty, hunger, and equitable national economic growth. One way to achieve this is by building empowered rural micro small and medium enterprises. Therefore, it is necessary to analyze the micro small and medium enterprises empowerment program to train village entrepreneurs to develop their businesses in a sustainable manner. This study aims to determine the right empowerment program to be applied to micro small and medium enterprises and identify stakeholders who help implement the program. Method: Determination of the research area using a purposive method, namely village owned enterprises and meatball home industry in Girirejo Village, Imogiri, Bantul, D.I.Y. The sampling method was carried out by purposive sampling using certain criteria. The data used are primary and secondary data using data collection methods in the form of observation, interviews, and documentation. Result: The results show that the empowerment programs that needed by micro, small and medium enterprises include production and operations management training, supply chain management training, digital marketing training, production and product development training, and marketing management training. Conclusion: This empowerment program optimizes and develops existing MSMEs in Girirejo Village for the better, the scope of this program is to increase the capacity of human resources and business capacity. Keywords: SDGs, Empowerment, micro small and medium enterprises

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