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INDONESIA
Journal of Pain, Vertigo and Headache
Published by Universitas Brawijaya
ISSN : 27233979     EISSN : 27233960     DOI : https://doi.org/10.21776/ub.jphv
Core Subject : Science,
Neuroscience
JPHV - Journal of Pain, Headache and Vertigo is a peer-reviewed and open access journal that focuses on promoting pain, headache and vertigo. This journal publishes original articles, reviews, and also interesting case reports. JPHV - Journal of Pain, Headache and Vertigo is an international scientific journal, published twice a year by PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia.
Arjuna Subject : Ilmu Syaraf - Neorologi
Articles 7 Documents
 1 
Search results for , issue "Vol. 6 No. 2 (2025): September" : 7 Documents clear
PREVALENCE OF NEUROPATHIC PAIN IN LOW BACK PAIN PATIENTS AT COMMUNITY HEALTH CENTER M, Muna; Pambudi, Pagan
Journal of Pain, Headache and Vertigo Vol. 6 No. 2 (2025): September
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2025.006.02.01

Abstract

Low back pain (LBP) is a musculoskeletal disorder that is widely found in the community starting at the age of 25 years and increasing at 50 years. Patients who experience LBP mostly experience neuropathic pain as much as 37% which complicates management. The neuropathic pain component is rarely considered in First Level Health Facilities (FKTP) due to lack of knowledge about simple clinical instruments that can identify pain characteristics and lack of data or research on neuropathic pain in LBP in FKTP so that the management of neuropathic pain in LBP in FKTP is less comprehensive. Therefore, research on neuropathic pain in LBP patients in primary care facilities needs to be done. This research aim to determine the prevalence of neuropathic pain among LBP patients at Puskesmas Simpang Empat 2 Banjar Regency. The study approach used was descriptive, using variables such as Low Back Pain (LBP), age, and gender. This research included LBP patients from Puskesmas Simpang Empat. 2.The research employed Pain Detection Questionnaire (PD-Q). The sample method used was incidental sampling. The results shows that During the study period, 95 samples were collected, with LBP patients with neuropathic pain accounting for 42 (44.2%), nociceptive 32 (33.7%), and ambiguous 21 (22.1%). According to gender, 58.9% were women and 41.1% were men. The greatest age group (40-49 years) had a frequency of 27.4%, while the lowest frequency (<20 years) was only 1.1%. Neuropathic pain is a prevalent issue in clinical practice.
CHARACTERISTICS OF LOW BACK PAIN IN NEUROLOGY OUTPATIENT Arnetha, Tiffani Shavira; Devy, Monica Sari; Payangan, Natan
Journal of Pain, Headache and Vertigo Vol. 6 No. 2 (2025): September
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2025.006.02.4

Abstract

Introduction: Low back pain is a significant global health issue. This condition not only causes physical discomfort but can also reduce the quality of life and productivity of individuals. This study aims to determine the characteristics of patients with low back pain at  Mampang Prapatan General Hospital. Methods: This study was a descriptive cross-sectional study using secondary medical record data from Mampang Prapatan General Hospital  in 2024. The sampling technique used in this study was simple random sampling. Results: There were 40 samples in this study, 31 samples were female (77.5%) and 9 samples were male (22.5%). The average age was 55.6 years old, with the largest age group being those over 60 years old (42.5%). The most common nutritional status was grade 1 obesity (47.5%). Radiating pain was most frequently reported pain (67.5%). Radiological examination using lumbosacral x-ray showed that the most common finding was lumbar spondylosis (57.5%). The most commonly used treatment was a combination of pharmacological and non-pharmacological therapy, specifically physiotherapy combined with analgesics and anti-spasmodic drugs. Conclusion: It can be concluded that the distribution of low back pain patients at Mampang Prapatan General Hospital were most prevalent among females, elderly individuals (>60 years), had obese nutritional status, and experienced radiating pain symptom. A combination of pharmacological and non-pharmacological management can be used to improve the quality of life for patients with low back pain.
A RARE CASE OF ISCHEMIC STROKE IN A YOUNG WOMAN WITH AUTOIMMUNE DISEASE: DIAGNOSIS AND THERAPY CHALLENGES Bulain, Stanley; Atalia, Arila; Lestari, Hotma; Pamarta, Trisna Belani; Rakhmatiar, Rodhiyan
Journal of Pain, Headache and Vertigo Vol. 6 No. 2 (2025): September
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2025.006.02.02

Abstract

Introduction: Stroke is a leading cause of death and disability worldwide and is considered a disease of the elderly. However, recent trends indicate an increase in stroke cases in young adults due to autoimmune causes. Stroke in young adults directly impacts health, productivity, society, the economy, and the health system. Case: A 30-year-old woman presented with sudden, intermittent weakness of one half of her body for 2 days. Physical examination revealed mild paralysis of the right 7th and 9th nerves, hemiparesis, hemihypesthesia, hemiparesthesia, increased physiological reflexes, and positive Hoffman and Tromner reflexes in the right extremity. A CT scan was normal, and the ANA test was positive. The patient was hospitalized for 7 days and given citicoline 500 mg once, azathioprine 50 mg twice, hydroxychloroquine 1200 mg once, acetylsalicylic acid 200 mg once, and pulse methylprednisolone 125 mg four times. She gradually improved. The patient was referred to the RSSA for MRI and MRA, which revealed a chronic infarction extending from the corona radiata to the left lentiform nucleus and no visible ACA segment A1 structure. The patient experienced a generalized tonic-clonic seizure lasting 2 minutes during the DSA. Diazepam 7.5 mg, Metamizole 1 g, and Nicardipine 3 mg/hour were administered, and the patient subsequently regained consciousness. The DSA results showed total occlusion of the ACA segment A1. The patient was diagnosed with CVA infarction with total occlusion of the ACA segment A1, with suspected autoimmune disorder. The patient was discharged three days later and planned for observation. Conclusion: Ischemic stroke in young adults with autoimmune disorders is a serious condition that requires special attention. Antiphospholipid antibody-related hypercoagulability and vascular complications such as vasculitis are the main mechanisms of stroke in this population. Further evaluation for underlying autoimmune disease is necessary for further treatment decisions.
EFFICACY OF ROBOT-ASSISTED THERAPY FOR ANKLE REHABILITATION IN STROKE PATIENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS Michelle Taruna, Dea; Athifah Nur Azizah Arif; Izzati, Nisrina Khansa; Salsabila, Pricillia Laurenza; Adams, Fayyaza Faiz
Journal of Pain, Headache and Vertigo Vol. 6 No. 2 (2025): September
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2025.006.02.03

Abstract

Introduction: Stroke is characterized by an obstruction or reduction in blood supply, leading to decreased oxygen supply to the brain. This disease is the second leading cause of death worldwide and a leading cause of disability, including ankle disorders. Robot-Assisted Therapy (RAT) presents as a potentially effective ankle rehabilitation approach to improve walking and balance in stroke survivors. Unlike conventional ankle rehabilitation, RAT provides more repetitive and precise training. To address the gap in stroke rehabilitation, particularly in ankle function, this study was conducted to investigate the efficacy of various RATs in ankle rehabilitation in stroke patients. Methods: We conducted a literature search through PubMed, Scopus, Proquest, Sage, and EBSCOhost to assess RAT until August 12, 2024. The keywords used were (“Stroke” OR “Post-stroke” OR “Stroke rehabilitation”) AND “Robots” AND “Ankle” and their synonyms. Results: Five studies, with a total of 156 samples, were included in the qualitative and quantitative analyses. Meta-analysis showed that RAT ankle significantly improved walking speed with a Standardized Mean Difference (SMD) of 1.13 (95% CI: 0.32, 1.94; P = 0.006) and Active Range of Motion (AROM) with a SMD of 2.08 (95% CI: 1.5, 2.66; P < 0.00001). However, other parameters assessed in this study, namely the Berg Balance Scale (BBS) and Fugl-Meyer Assessment for Lower Extremities (FMA-LE), did not show significant effects in the intervention group compared to the control group. Conclusion: Robot-Assisted Therapy (RAT) shows promising potential to improve ankle rehabilitation in stroke patients. In addition, this study proves that RAT significantly improves walking speed and active ankle range of motion.
ANALYSIS OF INDONESIAN NATIONAL DATA FOR RELATIONSHIP BETWEEN PREVALENCE OF HYPERTENSION, PHYSICAL ACTIVITY, AND HIGH-RISK FOOD CONSUMPTION WITH STROKE PREVALENCE Haq, Nabiila Ala Qoonita Najma; Ernanda, Shelby Amrus; Marhaendraputro, Eko Arisetijono
Journal of Pain, Headache and Vertigo Vol. 6 No. 2 (2025): September
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

physical activity, and high-risk food consumption. This study aimed to analyze the relationship between these risk factors and stroke prevalence across Indonesia, using data from the Indonesian Health Survey covering 514 districts/cities in 38 provinces. The analysis focused on hypertension prevalence, physical activity levels, and dietary habits (particularly high salt intake). Spearman correlation results showed a significant association between hypertension and stroke prevalence (P < 0.001, r² = 0.451). In contrast, no significant association was found between low physical activity and stroke (P = 0.161, r² = 0.05), nor between high salt intake and stroke (P = 0.110, r² = 0.06). In conclusion, the study confirms that hypertension is significantly associated with an increased risk of stroke in Indonesia, emphasizing the need for interventions targeting hypertension to reduce stroke cases nationwide. While low physical activity and risky dietary habits did not show strong associations with stroke prevalence, these factors still warrant attention.
RIVASTIGMINE TRANSDERMAL PATCH FOR ALZHEIMER’S DISEASE: A SYSTEMATIC REVIEW Baskoro, Firza Yoga; Hassa, Nazwan; Hajar, Nabil; Balqis, Indira Aura
Journal of Pain, Headache and Vertigo Vol. 6 No. 2 (2025): September
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Alzheimer's disease (AD) is the most common type of dementia disease. Acetylcholinesterase inhibitors (AChE-I) plays a pivotal role by increasing acetylcholine levels in the brain to improve cognitive function of Alzheimer's patients. Several agents including cholinesterase inhibitors such as donepezil and galantamine, as well as the NMDA receptor antagonist memantine are known for its benefit in increasing acetylcoline . However, Rivastigmin is the only AChE-I agent available in patch preparation. Objective : This study aims to evaluate the efficacy of Rivastigmin patch in improving cognitive function using the Alzheimer's Disease Assessment Scale Cognitive Subscale (ADAS-Cog) in Alzheimer's disease patients. Methods: This research was conducted in accordance with the Systematic Review without Meta-Analysis (SWiM) guideline. A systematic database search was conducted in Medline, Google Scholar, and Cochrane Central Libraries using a pre-determined search query. Articles were screened by independent reviewers for eligibility to be included in the study. After risk of bias was conducted, seven studies were included for this research. Results: The included studies reported varied outcomes regarding cognitive improvement in Alzheimer's disease (AD) patients, depending on the dosage of Rivastigmine used. Overall, Rivastigmine was found to slow the progression of cognitive decline, as measured by the ADAS-Cog, and in some cases, even reduced ADAS-Cog scores by up to 3 points . Rivastigmine patch is known to inhibit the action of acetylcholinesterase enzyme which causes degradation of acetylcholine in the synapse gap, ultimately improving the cognitive of AD patients. Studies also mention that Rivasitgmine patch preparation has better tolerance to side effects compared to capsules or placebo. Conclusion: Rivastigmine patch shows improvement of cognitive status in Alzheimer's patients and has good tolerability compared to placebo or capsule preparations. the long-term efficacy and safety of the rivastigmine patch remain underexplored, and the generalizability of the findings to diverse patient populations is uncertain.
PATHOPHYSIOLOGY, DIAGNOSIS, AND MANAGEMENT OF NEUROPATHIC PAIN Puteri, Lintang Firdhani Nabila; Rahmawati, Dessika
Journal of Pain, Headache and Vertigo Vol. 6 No. 2 (2025): September
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Neuropathic pain is a type of chronic pain resulting from lesions or disorders of the somatosensory nervous system. This condition is often difficult to recognize and manage due to the complexity of its mechanisms and the variation in clinical symptoms. Objective: This article aims to review the pathophysiological mechanisms, diagnostic approaches, and management strategies for neuropathic pain based on current scientific literature. Result: The main mechanisms of neuropathic pain include ectopic activity, central sensitization, dysfunction of descending inhibitory pathways, and glial cell activation. Diagnosis is established through a combination of detailed history taking, neurological examination, screening tools such as DN4, and supporting investigations such as EMG-NCV, QST, skin biopsy, ultrasonography, and MRI. Pharmacological therapy includes the use of tricyclic antidepressants, SNRIs, anticonvulsants, and topical agents, with an individualized and stepwise approach. Advanced imaging techniques such as MRI and CT play a critical role in detecting structural lesions. Conclusion: The diagnostic and therapeutic approaches to neuropathic pain should be multimodal and mem-based. Integration of clinical and supporting examinations is key to improving diagnostic accuracy and therapeutic effectiveness.

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