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All Journal Journal of Environmental Engineering and Sustainable Technology Jurnal Kedokteran MNJ (Malang Neurology Journal) Journal of Information Technology and Computer Science Jurnal Pengembangan Teknologi Informasi dan Ilmu Komputer Journal of Islamic Medicine Journal of Pain, Vertigo and Headache Jurnal Kesehatan Masyarakat

Eko Arisetijono

Universitas Brawijaya

Author-ID : 549201

Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Mechanical Engineering Medicine & Pharmacology Neuroscience Public Health

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CORRELATION OF C-REACTIVE PROTEIN LEVELS WITH CLINICAL OUTCOME INTRACEREBRAL HEMORRHAGE STROKE PATIENTS Setianto, Catur Ari; Purnomo, Hari; Marhaendraputro, Eko Arisetijono; Santoso, Widodo Mardi
Malang Neurology Journal Vol 1, No 1 (2015): January
Publisher : Malang Neurology Journal

Background. Increased levels of markers of inflammatory factors after hemorrhage stroke was able to predict poor clinical outcome. Until now, the role of C Reactive Protein (CRP) in the local inflammatory response and clinical determinants output remains unclear.Objective. To investigate the correlation of CRP level with poor clinical outcome as measured by Barthel Index. Methods. This study was an observasional cohort porspective study performed on haemorrhage stroke patients in Saiful Anwar General Hospital in Februari 2014 until April 2014.Results. There was significant correlation (p=0,01, r=0,613) between CRP levels to poor clinical outcome measured by Barthel Index.Conclusion. C Reactive Protein levels could predict poor clinical outcome as measured by Barthel Index in intracerebral hemorrhage patients.

BETA AMYLOID POLYCLONAL ANTIBODY IMMUNOGENICITY AS EARLY DEVELOPMENT STUDY OF EARLY DIAGNOSIS FOR ALZHEIMERâ€™S DISEASE Indra, Muhamad Rasjad; Marhaendraputro, Eko Arisetijono; Hidayat, Rudi Rakhmad
Malang Neurology Journal Vol 3, No 1 (2017): January
Publisher : Malang Neurology Journal

Background. Alzheimer's disease is a progressive neurologic disease of the brain that triggers irreversibleÂ neuronal cell loss, which can interfere with social and occupational functioning. The theory of ACHÂ (Amyloid Cascade Hypothesis) states there are deposits and misfolding of beta amyloid protein thus leadÂ to the formation of plaques and tangles in neurons cells.Objective. To identify the immunogenicity of beta amyloid polyclonal antibodies that can be developed as a first step early diagnosis of Alzheimer's disease.Methods. Rrandomized group post test only design conducted on rabbits. Blood samples were taken from rabbits that had been injected antigen once a week for 5 weeks. Variables were found in this study is the formation of beta amyloid polyclonal antibody with detection levels using dot blot and ELISA methods.Results. It has been reproduced specific polyclonal antibody beta amyloid which has been evidenced by the bond between the antigen with the antibody in a dot blot.Conclusion. The beta amyloid antibodies can be produced through production techniques with a polyclonal antibody against beta amyloid antigen induced rabbit.

EXTRACRANIAL METASTASIS OF GLIOBLASTOMA: A RARE CASE Rahmawati, Dessika; Marhaendraputro, Eko Arisetijono; Kurniawan, Shahdevi Nandar; Wirathmawati, Andina
Malang Neurology Journal Vol 5, No 1 (2019): January
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.01.10

Glioblastoma is the most common primary malignant tumor in the neural tissue and a highly aggressive primary tumor in human. It involves glial cells in 52% of functional brain tissue cases and 20% of all intracranial tumors. Extra cranial metastasis of Glioblastoma is very rare. Metastasis outside CNS was uncommon in GBM but it could occur with frequency 0.2% and can spread in head and neck sites. The mechanism of this spread is not understood yet. The extracranial spread routes were speculated on the direct lymphatic connections, the venous system and the adjacent structure like dura and bone. We present a case of female patient with a known glioblastoma who had an extracranial metastasis on her left neck with complete Radiotherapy n Chemotherapy and survive more than 2 years.

Profil Probabilitas Stroke Iskemik Di Kota Malang Dan Batu: Aplikasi Skor Risiko Stroke Framingham Harahap, Herpan Syafii; Arisetijono, Eko; Afif, Zamroni
Jurnal Kedokteran Vol 5 No 3 (2016)
Publisher : Faculty of Medicine Universitas Mataram

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Pendahuluan: Stroke saat ini merupakan salah satu penyebab kematian dan kecacatan utama di dunia, dimana 85% kasus merupakan stroke iskemik. Dengan mengetahui faktor-faktor risiko stroke iskemik, dapat dilakukan prediksi risiko untuk mengalami stroke iskemik dengan menggunakan skor risiko stroke Framingham. Tujuan: Untuk mengetahui profil probabilitas stroke iskemik di Kota Malang dan Batu menurut skor risiko stroke Framingham. Metode: Penelitian deskriptif cross-sectional ini menggunakan teknik consecutive random sampling untuk pengambilan sampel penelitian. Dilakukan pengukuran persentase dan stratifikasi skor risiko stroke Framingham terhadap 109 orang menurut jenis kelamin (n=109). Dalam penelitian ini juga dilakukan pengukuran parameter indeks massa tubuh (IMT), lingkar perut, rasio lingkar panggul-perut, dan kadar kolesterol total dan asam urat serum untuk dikorelasikan dengan persentase skor risiko stroke Framingham. Hasil: Sebanyak 72 orang (66,06%) memiliki risiko stroke iskemik yang rendah, 20 orang (18,34%) memiliki risiko sedang, dan 17 orang (15,60%) memiliki risiko tinggi. Hasil uji korelasi menunjukkan persentase risiko stroke memiliki korelasi negatif dengan IMT (p=0,030;r=-0,208) dan korelasi positif dengan kadar asam urat serum (p=0,018;r=0,244). Tidak didapatkan korelasi antara persentase skor risiko stroke Framingham dengan lingkar perut (p=0,120), rasio lingkar perut-panggul (p=0,070), dan kadar kolesterol total serum (p=0,208). Kesimpulan: Sepertiga sampel penelitian yang memiliki risiko stroke iskemik sedang-berat berdasarkan skor risiko stroke Framingham.

NEUROPATHIC PAIN IN PATIENT WITH POST OPERATIVE SCHWANNOMA: A CASE REPORT PRIMARY INTRADURAL EXTRAMEDULLAR SPINAL CORD TUMOUR Santoso, Widodo Mardi; Nurlela, Siti; Marhaendraputro, Eko Arisetijono; Rahmawati, Dessika
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.7

Majority of spinal cord tumour is a benign tumour with symptoms are due to spinal cord compression. One of the symptoms that are often difficult to treat is a sensory deficit. The authors report a case of primary intradural extramedullar spinal cord tumour in 57-year-old man. This tumour was presenting symptoms of chronic low back pain, gradual progressive inferior paraplegia, and sensory deficit on both legs. MRI thoracal showed intradural lesion at Th 4-5-6, with isointensity on T1-weighted images and hyperintensity-isohomogen on T2-weighted images. The tumour was completely resected, and histopathology examination revealed schwannoma types. Patient showed a clinical improvement in motoric function noticeable after surgery, but showed sensory deficits sequelae requiring therapy for neuropathic pain.

THE SIDE EFFECTS OF CHEMOTHERAPY IN GLIOMA Raisa, Neila; Marhaendraputro, Eko Arisetijono
Malang Neurology Journal Vol 5, No 2 (2019): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.02.9

The increasing number of people who survive in the long term because of the advanced of glioma therapy with chemotherapy causes more slowly emerging neurologic side effects. Currently, there were three medical treatments are approved by the FDA for the management of glioblastoma namely temozolomide, carmustine wafer, and bevacizumab. However, most of the traditional chemotherapy drugs have a target in cell proliferation and cause toxicity of healthy cells. The side effects of chemotherapy on central nervous systems are chemobrain, acute encephalopathy, leukoencephalopathy, cerebellar dysfunction, and spinal cord toxicity. In addition, severe chemotherapy side effects may also occur in the peripheral nervous system called Chemotherapyinduced peripheral neuropathic pain (CIPNP). The clinician should recognize the symptoms of those side effect in glioma patients who received chemotherapy.

NEUROLOGICAL MANIFESTATION ON HOSPITALIZED PATIENT WITH PROBABLE COVID-19 IN SAIFUL ANWAR HOSPITAL INDONESIA (SERIAL CASES) Munir, Badrul; Rianawati, Sri Budhi; Kurniawan, Shahdevi Nandar; Santoso, Widodo Mardi; Arisetijono, Eko; Candradikusuma, Didi; Heri, Sutanto; Chozin, Iin Noor; Dwi, Pratiwi Suryanti; Astuti, Tri Wahju; Asmiragani, Syaifullah
MNJ (Malang Neurology Journal) Vol. 6 No. 2 (2020): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

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Background: Coronavirus disease 2019 (Covid-19) caused by SARS-Cov-2 had been spreading worldwide including Indonesia, but In Indonesia, it was difficult to diagnose confirmation Covid-19 by Polymerase Change Reaction (PCR). and in clinical practice to treat covid-19,Â Indonesia Health Ministry use term probable covid-19 for patients under observation Covid-19, but study for neurological manifestation on Â probable Covid-19 is very lacking.Objective: Knowing the neurological manifestation of patient probable Covid-19.Methods: Observational study from Covid-19 medical record and neuro-Covid-19 medical record of all probable Covid-19 hospitalized in the isolation ward of Saiful Anwar Hospital (RSSA) Malang since March-May, 2020 (3 months). Probable Covid-19 criteria were given by Covid-19 task force team based on Health Minister Indonesia criteria. This criterion was based on clinical manifestation (severe upper respiratory symptoms, or mild-severe pneumonia), radiologic examination (lung infiltrate and or chest CT scan), and laboratory examination. Neurological manifestation is based on clinical symptom appeared while patient hospitalized, supported with radiologic and laboratory data which was supervised by neurologist or neurologist resident. All data was inputted to neuro-Covid-19 e-registry on the smartphone application, sent periodically to the data center in Neurology Department RSSA Malang.Results: A hundred and fourteen probable Covid-19 was registered with mean age 34,5 year old and mostly at the young age of 20-50 years (38%). The neurological manifestation was observed in 4 patients (3,4% from all possible Covid-19 patients) with thrombotic stroke as the most common manifestation (50%), followed by myelum tumor (25%) and hypoxia encephalopathy (25%). Stroke patients in probable Covid-19 had old age (72 and 82 years) accompanied by several comorbid such as hypertension, DM and CVA history and Covid symptoms of cough, shortness of breath and fever. Hemiparesis was found improved with aspirin and neurotropic therapy. Patient with myelum tumor had a covid symptom of shortness of breath, cough, and fever with UMN tetraparesis. Previous MRI examination results suspected meningioma. The patient died while hospitalized. Patients with hypoxia encephalopathy admitted with decreased consciousness due to shortness of breath with acidosis respiratory symptoms (pH 7,22 ). This condition improved after oxygenation without focal neurologic deficit.Conclusion: Neurological manifestation in probable Covid-19 was 3,4% of all patients. The most common diagnosis was a thrombotic stroke, followed by myelum tumor, hypoxia encephalopathy, and mortality rate is 25%.

SISTEM PENDUKUNG KEPUTUSAN DETEKSI DINI PENYAKIT STROKE MENGGUNAKAN METODE DEMPSTER-SHAFER Deby Putri Indraswari; Arief Andy Soebroto; Eko Arisetijono Marhaendraputro
Journal of Environmental Engineering and Sustainable Technology Vol 2, No 2 (2015)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Brawijaya

Stroke is a neurological function disorders caused by impaired blood flow in the brain. Stroke is the third most common cause of death in developed countries, after heart disease and cancer. This causes a stroke to watch. Early prevention through medical examination needs to be done to reduce the high rate of risk of stroke. The detection of the risk of stroke is determined when knowing the criteria of risk factors is complete and structured. But sometimes the detection of the risk of stroke is difficult to determine if there are risk factors that have forgotten or not structured so that doctors can experience problems or ambiguous to make diagnosis. To overcome the problem of semi-structured pattern, it can be solved using decision support systems (DSS) with intelligent computing. SPK early detection of stroke constructed using methods Dempster Shafer. In the study can detect the level of risk of stroke is high risk, medium, and low with 8 input risk factors. Based on the data used in this system is obtained accuracy of 90%. So that it can be concluded that SPK is constructed with Dempster Shafer method to function well for detecting stroke.

MYOFASCIAL PAIN SYNDROME Shahdevi Nandar Kurniawan; Nidia Suriani; Eko Arisetijono Marhaendraputro; Dessika Rahmawati
Journal of Pain, Headache and Vertigo Vol. 1 No. 1 (2020): March
Publisher : Journal of Pain, Headache and Vertigo

Pain is a sensory experience that is responded to as an unpleasant stimulus that is often caused by tissue damage. Perdossi defines pain as an unpleasant sensory and emotional experience due to tissue damage, both actual and potential, or which is described in the form of such damage. Pain can affect everyone regardless of sex, age, race, social status, and occupation. Myofascial pain syndrome (MPS) is a term used to describe the condition of acute or chronic pain in musculoskeletal soft tissue. This is indicated by the findings of sensory, motoric, and autonomic symptoms related to myofascial trigger points (MTRP). The symptoms can be local or far from MTRP. In MPS that are far from MTRP, the pain patterns that appear are usually pain is pervasive The most common location for MPS is the neck and back. The purpose of writing this literature review is to explain epidemiology, clinical manifestations, pathogenesis mechanisms, pathophysiology mechanisms, and management in patients with myofascial pain syndrome. Myofascial pain syndrome is a pain syndrome in muscles that includes musculoskeletal abnormalities and MPS management shows that most interventions, both medical therapy and non-medical therapy, still need studies to prove its effectiveness.

STROKE AFTER ELECTRICAL INJURY : CASE REPORT Eko Arisetijono; Catur Ari Setianto; Sri Budi Rianawati; Masruroh Rahayu; Rodhiyan Rakhmatiar
Journal of Pain, Headache and Vertigo Vol. 1 No. 2 (2020): September
Publisher : Journal of Pain, Headache and Vertigo

Electrical injury ranging widely reported caused variety of clinical manifestations including brain. Cerebral infarction is one of the manifestation either after low or high voltage electrical injury. We report the case of 49 â€“ year old male who suffered a household electrical injury (110 â€“ 220 Volt) while he was installing the light bulb. He found unconsciousness with left hemiparesis and also central paresis of the left facial nerve (Cranial Nerve VII). The Head Computed Tomography Scan (CT scan) showed wide infarction at right hemisphere which the territory of right cerebral media artery which can be caused by electrical injury.Â Â Â

Co-Authors Agustin, Aisyiyah Alviana Arief Andy Soebroto Asmiragani, Syaifullah Badrul Munir, Badrul Catur Ari Setianto Catur Ari Setianto, Catur Ari Chozin, Iin Noor Deby Putri Indraswari Dessika Rahmawati Didi Candradikusuma Dwi, Pratiwi Suryanti Ernanda, Shelby Amrus Haq, Nabiila Ala Qoonita Najma HARI PURNOMO Heri, Sutanto Herman Tolle Herpan Syafii Harahap Hidayat, Rudi Rakhmad Indriyana, Yanna Ismiarta Aknuranda Karmia Larissa Br Pandia Masruroh Rahayu Muhamad Rasjad Indra Nanik Setijowati Nidia Suriani Pradhana, Satwika Priana, Aan Jelli Rahmawati, Dessika Rahmawati, Dessika Raisa, Neila Rivarti, Arina Windri Rodhiyan Rakhmatiar Shahdevi Nandar Kurniawan, Shahdevi Nandar siti nurlela Sitompul, Boyke Sri Budhi Rianawati, Sri Budhi Sri Budi Rianawati Tri Wahju Astuti, Tri Wahju Widodo Mardi Santoso Widodo Mardi Santoso, Widodo Mardi Wirathmawati, Andina Yulia Damayanti Yuyun Yueniwati Zamroni Afif

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