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Zahratul Aini
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JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Published by Universitas Islam Indonesia
ISSN : 20854145     EISSN : 25272950     DOI : 10.208885/JKKI.Vol10.Iss3.art5
Core Subject : Health,
Medicine & Pharmacology Public Health
JKKI: Jurnal Kedokteran dan Kesehatan Indonesia is a peer-reviewed journal in the field of medical and health sciences. This journal is designed as a place of dissemination of information and scientific knowledge, which publishes three times a year. It publishes original article, article review, and case report. These comprise of biomedical sciences, clinical medicine, public health sciences, and medical science education.
Arjuna Subject : Kedokteran - Kedokteran Keluarga
Articles 468 Documents
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Risk factors of stroke survivors' quality of life Oktania Candrawati; Ronny Tri Wirasto
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 8, No 3, (2017)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol8.Iss3.art6

Abstract

Background : Stroke can lead into long-term disabilities which may affect stroke survivors' quality of life (QOL). The importance of stroke survivors' QOL is still getting little attention.Objective : To know stroke survivors' QOL and the risk factors associate with, i.e.:sociodemographic, activity daily living, cognitive, and depression.Methodology : This cross-sectional study was conducted in April-October 2014 at neurology clinic Dr.Sardjito Hospital, Yogyakarta. Subjects' criteria were minimal four weeks after the first stroke incident and came with their primary caregiver. Subjects were interviewed about their sociodemographic condition and were given WHOQOL-BREF, Mini Mental State Examination (MMSE), and Beck Depression Inventory (BDI) questionnaires. Meanwhile, their caregiver was interviewed with Barthel Index (BI) questionnaire. Bivariate chi-square and logistic regression analysis was done.Results : There were 64 subjects analyzed. QOL domain affected the most is physical, while the least is environment. Bivariate analysis found not working after stroke and higher BDI score associate with lower WHOQOL-BREF physical (r=9.286, p<0.01 and r=5.361, p<0.05) and psychological (r=3.935, p<0.05 and r=14.527, p<0.001) domain. No risk factor associates with WHOQOL-BREF social relationship domain. Higher BDI score associates with lower WHOQOL-BREF environment domain (r=5.861, p<0.05). Regression analysis shows older age (p<0,05) and not working after stroke (p<0,01) are risk factors for lower WHOQOL-BREF physical domain, while higher BDI score is risk factor for lower WHOQOL-BREF psychological (p<0,01) and environment (p<0,05) domain.Conclusions : Older age and not working after stroke incident are risk factors for physical domain of QOL. Depression is risk factor for psychological and environment domain of QOL.
Oral N-Acetyl cysteine lowered IL 6 level among stage V chronic kidney disease patients on Continuous Ambulatory Peritoneal Dialysis (CAPD) Evi Nurhayatun
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 8, No 3, (2017)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol8.Iss3.art7

Abstract

Background. IL 6  level is increased in stage V CKD patients on CAPD. N-Acetyl Cysteine is a compound containing thiol with antioxidant and anti-inflammatory effects.Objective. To examine the effect of oral NAC on IL 6 level in stage V CKD patients on CAPD.Method. An experimental research with Randomized Double Blind Control Trial,  involving 30 CKD patients on CAPD in Dr Moewardi Hospital. They were divided into control group/placebo (15 patients) and oral NAS treatment group (15 patients). IL 6 level was measured before and after 8 weeks of treatment.Result. Level of IL 6  before and after treatment in control group were (8.13 +7.62  vs 11.16 + 8.32 , p= 0,001), significantly (p<0,001). Level of IL 6 before and after treatment in treatment group were (9.72 + 7.29 vs 6.09 + 3.82, p = 0,002); lowered significantly (p<0,05).Conclusion. Oral NAC lowered the level of IL 6 in stage V CKD patients on CAPD.
In Vitro Anti-Inflammatory Activities of Ethanolic Extract Elephantopus Scaber Leaves Tomy Nurtamin; I Putu Sudayasa; Tien Tien
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 1, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss1.art9

Abstract

Background: Inflammation is a protective physiological response to tissue injury that can be caused by harmful stimuli. If the inflammatory process is prolonged and cannot restore to homeostatic conditions, this may lead to pathological effects that can damage cells and cause various diseases. Elephantopus scaber is a plant that can easily be found in Indonesia. Elephantopus scaber is a type of plant that is often used as a traditional medicines. Several studies have shown that the compound bioactive content contained in plants has enormous potential as alternative medicine.Objective: This present study was to investigate the anti-inflammatory activity of ethanolic extract of Elephantopus scabe leaves.Methods: The Elephantopus scaber leaves were extracted using ethanol solvent into different concentration (50 mg/mL, 100 mg/mL, and 120 mg/mL). Diclofenac sodium was used as the standard. Anti-inflammatory assays were performed by the human red blood cell (HRBC) membrane stabilization method and heat-induced hemolysis method. Phytochemical screening that used in the present study was a conventional method.Results: Phytochemical screening showed the presence of flavonoids, tannins, and saponins. In the present study, ethanolic extract of Elephantopus scaber leaves has anti inflammatory activity by protecting the stability of red blood cell membrane. The highest protection capability possessed by the ethanolic extract of Elephantopus scaber leaves in both human red blood cell (HRBC) membrane stabilization method and heatinduced hemolysis method was at a concentration of 100 mg/mL.Conclusion: The ethanolic extract of Elephantophus scaber has antiinflammatory activities by in vitro assays.
Cardenolides source and therapeutic effects Zahia Kabouche
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 8, No 3, (2017)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol8.Iss3.art1

Abstract

No Abstract
Clinical symptoms and risk factors comparison of ischemic and hemorrhagic stroke Rosa De Lima Renita Sanyasi; Rizaldy Taslim Pinzon
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 1, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss1.art3

Abstract

Backround: It is very important to know and detect various stroke symptoms because stroke is an emergency condition. Lack of knowledge about stroke symptoms leads to delay on stroke treatment.Objective: The aim of this study is to compare clinical symptoms and risk  factors between ischemic and hemorrhagic stroke.Methods: This study was a case control study. The subjects in this study were ischemic and hemorrhagic stroke patients. Subject data were recorded in electronic stroke registry at Bethesda Hospital, Yogyakarta.Results: The most common clinical symptoms in both groups were limb weakness (76.4% vs 71.4%), whereas the rarest was face drooping (2% vs 3.6%). Hypertension was the most common risk factor in both group (48% vs 71.4%), whereas atrial fibrillation was the rarest. This study did not find the specific correlation between any clinical symptoms to ischemic stroke incidence, however, decrease a level of consciousness was significant to hemorrhagic stroke incidence (OR: 2.738, 95% CI: 1.503-4.990, p: 0.001). Previous stroke (OR: 2.413, 95% CI: 1.314-4.433, p: 0.005) and dyslipidemia (OR: 4.862, 95% CI: 2.613-9.045, p: 0.000) were significant increasing risk of ischemic stroke. Hypertension was only the significant increasing risk of hemorrhagic stroke (OR: 3.680, 95% CI: 2.086-6.492, p: 0.000).Conclusion: Decrease level of consciousness has a significant correlation to hemorrhagic stroke incidence, but there is no specific symptom correlate to ischemic stroke incidence. Previous stroke and dyslipidemia are significant risk factors for ischemic stroke, whereas hypertension is the only significant risk factor for hemorrhagic stroke.
Multiple Intracranial Tuberculomas: A Rare Case of CNS TB Agus Nur Salim Winarno
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 1, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss1.art10

Abstract

Tuberculosis (TB) is still to be worlds major health concern. About 8,6 million cases occur in 2012 worldwide. TB doesnt mainly affect the lungs but it can affect extra pulmonary system. Central nervous system (CNS) is one complication of TB that should be considered as it is associated with high morbidity and mortality. Tuberculoma is one form of CNS TB that is rare and challenging in diagnostic. It will be presented a case of adult female with history of on-going TB treatment that presents with altered mental status, focal neurological signs, and increased ICP signs and symptoms. The head CT with contrast shows multiple ring enhancement with perilesional edema that consistent with brain tuberculoma. She was admitted to ICU and she got anti-TB drugs, and systemic steroid.
Peripartum Cardiomyopathy (PPCM) : Case Report and Review of Literatures Befrie Mahaztra Sudarman
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 1, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss1.art11

Abstract

Introduction: Peripartum cardiomyopathy (PPCM) is a disease characterized by an enlargement of the heart muscle wall. The disease occurs in the last month of pregnancy up to 5 months postpartum, with no previous history of heart disease. The etiology of the disease is unclear. Early recognition of this case can lead to decrease in morbidiy and mortality.Case: A 20-year-old woman came to the Emergency Unit with a shortness of breath. There is a history of give birth about 4 months ago. Physical examination shows a regular heart rhythm accompanied by rhonchi sound in the basal aspect of lung. In the M-mode analysis of ECG showed left ventricular systolic ejection function is decrease (56.5%) while the right ventricle is normal. In the Hospital, patient get treated with diuretics, aldosterone antagonist, angiotensin II receptor blocker and fluid management. Patient gave good responsed to the therapy regiment.Discussion: The early clinical manifestations of PPCM are difficult to recognize. In the majority of patients, 78% of symptoms are found at 4 months after delivery, only 9% of patients show symptoms in the last month of pregnancy. Clinical symptoms include atypical chest pain, abdominal discomfort, signs of pulmonary edema, orthopnea and paroxysmal nocturnal dyspnea. In the management of patients with PPCM is almost similar to management in other congestive heart disease.
Corpus alienum in rectosigmoid: a Case report Agung Widianto; Wahyu Kartiko Tomo; Fuad Dheni Musthofa; Ghana Hendra
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art11

Abstract

A 48-year old man, a referred patient from Wonosobo Hospital, presented to our hospital with severe lower abdomen to anal discomfort since seven days before admission. It is a sudden pain without apparent causes or triggers and accompanied by blood. The patient is uncooperative when asked about the history of inserting objects into the anus and his sexual behaviour. On plain x-rays, a picture of a tubular object in the rectosigmoid region was discovered. After the operation, a foreign body in the form of a Polyvinyl Chloride (PVC) pipe was extracted.
Comparison the level of Standard Deviation of N-N interval (SDNN) among Adolescent in Non Smokers and Smokers in Yogyakarta Nurfazrin H. Akuba; Nurvita Risdiana
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 1, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss1.art6

Abstract

Background: Smoking has a negative impact on health. It makes an imbalance of the autonomic nervous system (ANS). It influenced the standard deviation of N-N interval (SDNN). SDNN has a duty as indicator for ANS controlled, consequently, SDNN in smokers is lower than non smokers because of ANS imbalance. Therefore, smokers have high risk for non communicable disease (NCD) in the future.Objective: This research’s purpose was to know the comparison of SDNN level among smokers and non smokers adolescent.Methods: This research was non-experimental study with descriptive comparative design and cross sectional approach. The samples divided into 2 groups with each of group consists of 20 students. They were chose by purposive sampling techniques. SDNN level was measured by electrocardiogram (ECG) for 5 minutes with the provision that they should no tea, caffeine, alcohol consumption and no heavy exercise within 2 hours before data collected, feel free from desire to go to bathroom, feeling relax when data collection were performed. The data was analyzed by Mann Whithey test.Results: There was a significant difference of between smokers’ SDNN and non smokers’ with p= 0.038 (p<0.05). Smokers’ SDNN was lower than non smokers’.Conclussion: Smokers’ SDNN level was lower than non smokers’. 
Preliminary study of a-mangosteen nanoparticles in the sunscreen cosmeceutical product Hanny Setyowati; Wahyuning Setyani
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art10

Abstract

The growing interest in the cosmeceuticals by natural products has fostered research on the screening of plant-derived raw materials for identifying new antioxidants. Fruit peels as sources of powerful natural antioxidants are often the waste parts of various fruits from daily consumption or food industry. Among the fruit peels, mangosteen peel is an essential source of natural phenolic antioxidants. The a-mangosteen, known as the first compound of Garcinia mangostana L, has the most potent antioxidant activity among the other substances. The new application into sunscreen product will be potentially based on their activity to inhibit the photo-damaged caused by free radical elements from ultraviolet A and B (UVA and UVB). Thus, this formulation into a nanoparticle product may achieve a better effect and efficacy both as cosmetics and pharmaceutics.

Page 15 of 47 | Total Record : 468

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