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Arman Harahap
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armanhrahap82@gmail.com
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+6285370005518
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armanhrahap82@gmail.com
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Jl. SM. Raja, No 27, Kab. Labuhanbatu, Provinsi Sumatera Utara, 21419
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INDONESIA
International Journal of Health and Pharmaceutical (IJHP)
Published by CV. Inara
ISSN : -     EISSN : 2808845X     DOI : https://doi.org/10.51601/ijhp
Core Subject : Health,
International Journal of Health and Pharmaceutical (IJHP) e- ISSN : 2808-845X is a communication media and scientific publication in the health and pharmaceutical fields published by Inara Publisher. International Journal of Health and Pharmaceutical (IJHP) contains articles from research focusing on basic medicine, clinical medicine, epidemiology, preventive medicine (social medicine), pharmacy, and other medical fields. International Journal of Health and Pharmaceutical (IJHP) is published periodically four times a year (February, May, August and November).
Articles 426 Documents
Comparative Study of Methods for Producing Nanoemulsions Using Vegetable Oil as an Excipient: Narrative Review Dwi Cahyani, Ervita; Syukri, Yandi; Zubair, Sulaiman
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.451

Abstract

Nanoemulsions using vegetable oils as excipients have gained attention for their ability to improve the delivery and stability of bioactive compounds in pharmaceutical and food applications. This study aims to systematically compare various methods for preparing nanoemulsions with vegetable oil excipients. A narrative literature review was conducted, focusing on articles published between 2021 and 2025 from Google Scholar, PubMed, and ScienceDirect. The population comprised all relevant scientific articles, with purposive sampling based on inclusion criteria such as active DOI and accessibility. Data were analyzed qualitatively using content analysis to identify, group, and compare preparation methods, physicochemical characteristics, and product stability. Results indicate that high-energy methods like ultrasonication and high-pressure homogenization produce nanoemulsions with smaller, more uniform droplets and greater stability, while low-energy methods such as spontaneous emulsification are simpler but may yield less stable products. The choice of vegetable oil and surfactant significantly affects droplet size and stability. In conclusion, optimizing both the oil type and preparation method is essential for developing effective nanoemulsion-based products.
Comparison of the Effectiveness of Antihypertensive Drugs Captopril 25 mg and Amlodipine 5 mg in Lowering Blood Pressure in Hypertensive Patients Amal, Ichlasul; Marfuati, Sri; Istisakinah, Rini
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.455

Abstract

Hypertension is a major global health problem with increasing prevalence and significant risks of complications. This study aims to compare the effectiveness of Captopril 25 mg and Amlodipine 5 mg in lowering blood pressure among hypertensive patients. An analytical observational study with a cross-sectional design was conducted at Waruroyom Community Health Center, involving 70 patients divided equally into two groups. Data were collected using structured questionnaires, medication adherence sheets, and calibrated digital blood pressure monitors. Univariate and bivariate analyses were performed, including paired T-tests and Mann-Whitney tests. The results showed that both Captopril and Amlodipine effectively reduced systolic and diastolic blood pressure. However, Amlodipine 5 mg demonstrated a significantly greater reduction in diastolic blood pressure compared to Captopril 25 mg, while both drugs had similar effects on systolic blood pressure. The conclusion is that Amlodipine may be preferred for patients requiring greater diastolic blood pressure control, although both drugs are effective for systolic reduction.
Overview of Post-Operative Clinical Functional Results of Patients Undergoing Total Knee Replacement Procedures at Royal Prima Hospital Febriani Simanjuntak, Lorena; Alexander, Rico; Chiuman, Linda
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.456

Abstract

Total Knee Replacement (TKR) is a surgical procedure aimed at replacing damaged knee joints due to osteoarthritis or other conditions causing pain and dysfunction. This study aims to describe the clinical functional outcomes after TKR based on age and gender among patients at Royal Prima General Hospital, Medan. A descriptive cross-sectional design was used, involving 30 patients who underwent TKR between May and April 2025. Data were collected from medical records and assessed using the Oxford Knee Score (OKS). Statistical analysis was performed to evaluate the distribution of functional outcomes. The results showed that most patients were aged 71–82 years (53.5%) and female (76.7%). Younger patients (56–60 years) achieved better clinical function (Excellent category), while older patients (71–82 years) tended to have Moderate scores. Females demonstrated better clinical outcomes than males. The study concludes that age and gender influence post-TKR clinical function, with younger and female patients showing superior outcomes
The Relationship Between Preoperative Alvarado Score and Postoperative Anatomical Pathology Results In Acute Appendicitis at Royal Prima Marelan General Hospital In 2024 Anjayani, Imelda; Arafat Muchtar, Muhammad
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.458

Abstract

Background: Acute appendicitis is a common surgical emergency characterized by inflammation of the appendix, requiring timely diagnosis to prevent complications. The Alvarado score is a simple, inexpensive clinical tool designed to aid early diagnosis, while histopathological examination remains the diagnostic gold standard. This study explores the relationship between preoperative Alvarado scores and postoperative anatomical pathology results at Royal Prima Marelan Hospital in 2024. Methods: This cross-sectional analytic study analyzed medical records of 89 patients diagnosed with acute appendicitis who underwent appendectomy from January to December 2024. Data on demographic characteristics, Alvarado scores, and histopathological outcomes were extracted. Chi-square tests assessed correlation, while sensitivity and specificity analyzes evaluated the diagnostic performance of the Alvarado score. Results: Most patients were aged 15–24 years (55.1%) and female (56.2%). Alvarado scores ≥7 were observed in 85.4% of cases. Histopathology confirmed acute appendicitis in 95.5% of patients and chronic inflammation in 4.5%. A significant association was found between Alvarado scores and pathology results (p=0.000; OR=24.485). The Alvarado score demonstrated high predictive value for acute appendicitis. Conclusion: There is a strong correlation between preoperative Alvarado scores and postoperative pathological findings in acute appendicitis. The Alvarado score is a practical tool to improve diagnostic accuracy and reduce unnecessary surgeries. Future research should validate these findings with larger, prospective studies.
Ash, Protein And Salinity Analysis Of Integrated Formulation Of Herbs And Spices In Typical Simalungun “Tinuktuk” North Sumatera-Indonesia Damanik, Marini; Rosmiati, Risti; Permatasari, Tyas; Aulia Surbakti, Tia; Ayuni, Syarifah
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 3 (2023): August 2023
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i3.177

Abstract

Tinuknuk is a special sauce from Simalungun Regency, North Sumatra Province, tinuktuk warms the body and is believed to be able to cure various internal diseases, especially to help post-natal recovery. This study aims to determine the optimal nutritional value of the main components, namely red ginger with black pepper in the ratio composition: 70:30%, 60:40%, 50:50%, 40:60%, and 30:70% using the method oven at a temperature of 105℃. Then the ash content, protein content, and salt content were tested. The results showed that the ash content was 6.98%, respectively; 6.91%; 6.90%; 6.84%, and 6.73%. The salt content is 0.57%, respectively; 0.57%; 0.57%; 0.57%, and 0.57%. The protein content was 10.43%, respectively; 10.93%; 12.43%; 11.81%, and 10.62%.
Prioritizing Health Problems In Dukuh Demangan, Bantul, Yogyakarta Using Community Diagnosis And Hanlon Method Ruliyandari, Rochana; Indah Purwanti, Dwi; Nur Djanah, Sitti; Solikhah, Solikhah; Nuraisyah, Fatma
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 3 (2023): August 2023
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i3.189

Abstract

Community diagnosis is an activity to determine the existence of a problem by collecting data on the community. Community diagnosis is an activity to explore the main issues faced by the community based on existing facts and take strategies and follow-up plans to resolve these problems. The study aimed to determine the description of health problems through community diagnosis in Dukuh Demangan, Sewon District, Bantul Regency. The method used in this research is quantitative andqualitative. The study design used in implementing the Field Learning Experience is adescriptive study. After determining the priority of the problem using the Hanlon method. The result shows that hypertension is the priority of health problems in Dukuh Demangan.
The Effectiveness Of Giving Beet Juice On Hb Levels In Third Trimester Pregnant Women At Budhi Asih Hospital In 2022 Khairiah, Rahayu; Butar-Butar, Dessi
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 3 (2023): August 2023
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i3.196

Abstract

Anemia in pregnancy is a condition of the mother with a hemoglobin level of less than 11.0 gram/dl. Anemia can be prevented by consuming a balanced nutritious diet with sufficient iron intake to meet the body's needs. Heme iron is found in green vegetables, red meat, egg yolks, raisins, prunes, liver, oysters and some fortified cereals. Knowing the effectiveness of giving beetroot juice on Hb levels in third trimester pregnant women at Budh Asih Hospital. The research design is Quasi Experimental, with the Pretest and Posttest Control Group design. The population in this study were third trimester pregnant women with a gestational age of 28-36 weeks in the working area of Budhi Asih Hospital. The sampling technique used purposive sampling with the number of respondents being 30 third trimester pregnant women. The statistical tests used are the Mann-Whitney and Wilcoxon tests. The mean level of anemia before being given beetroot juice therapy in the intervention group was 6.33 and 6.93 in the control group. The mean level of anemia after being given beetroot juice therapy in the intervention group was 11.20 and in the control group was 4.80. beetroot juice therapy is effective for reducing the level of anemia in third trimester pregnant women with p value = 0.000 ≤ 0.05. Giving beetroot juice is effective for increasing hemoglobin levels in third trimester pregnant women at Budhi Asih Hospital. It is hoped that midwives can provide regular education to mothers who experience anemia about the benefits of beetroot juice to increase hemoglobin levels in third trimester pregnant women. Reading List : 16 (Year 2013-2022).
The Difference In The Effect Between Abdominal Breathing Techniques And Deep Back Massage On Reducing Labor Pain During The Active Phase I At Cengkareng Hospital In 2022 Farlikhatun, Lili; Hanurawati, Ira
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 3 (2023): August 2023
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i3.197

Abstract

Labor pain is the main problem experienced by maternity mothers (Rahayu, 2018). In Brazil, labor pain reaches more than 50% of the birth rate in a hospital which is the highest percentage worldwide (Alam, 2020). A preliminary study conducted by the authors, in May 2022, of 10 maternity mothers, 7 (70%) mothers felt severe pain, 2 (20%) mothers felt moderate pain, and 1 (10%) mothers felt mild pain. Therefore, the author is interested in conducting research on pain management with non-pharmacological methods in the form of relaxation and massage, on this occasion the author will conduct research on the difference between abdominal breathing techniques and deep back massage on reducing labor pain during the active phase I in physiological childbirth at Cengkareng Hospital in 2022. Knowing the difference in the influence between abdominal breathing techniques and deep back massage on reducing labor pain during the active phase at cengkareng hospital in 2022. This type of research is quantitative research, research design using quasi-experiments with one group pretest and posttest design. The sampling technique is a consecutive sampling technique, with a total sample of 44 respondents. Data processing using the T-test. Based on the results of independent analysis-test, a p value of 0.000 (p value < α 0.05) was obtained with a deep back massage standard deviation of 0.512 < 0.528 so that the results were obtained that H0 was rejected and Ha was accepted. From these results, it is concluded that there is a difference between abdominal breathing techniques and deep back massage in overcoming labor pain during the I active phase. Thus from both techniques more effective against pain adaptation response is deep back massage. The conclusion of this study is that deep back massage is more effective than abdominal breathing techniques with a standard deviation of 0.512 < 0.528 and a p value of 0.000 (p value < 0.05).
The Effect Of Avocado Fruit On The Nutritional Needs Of Pregnant Women Trimeter I At Pmb Tati Hidayat Jati Rahayu Bekasi In 2022 Nursila, Nursila; Sutarno, Maryati
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 3 (2023): August 2023
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i3.198

Abstract

Pregnant women most commonly experience anemia during the first trimester of pregnancy as a result of poor diet, which causes nausea and a lack of appetite. Chronic energy deficiency (CED) in pregnant women is caused by a long-lasting lack of energy intake in the mother, causing health problems. Pregnant women's nutritional intake has a significant impact on fetal growth during pregnancy, the incidence of low birth weight during delivery, and the baby's growth and development. Avocado (Persea americana) is a fruit that is very well known and popular with the public. Apart from having a delicious taste and soft texture, avocados also have several health benefits. The main components of avocados are carotenoids, fatty acids, minerals, phenolics, phytosterols, proteins, and many vitamins. Avocado is a fruit that is rich in vitamin A. Vitamin A has a role in erythropoiesis related to its function of synthesizing protein so that it will affect the growth of bone cells. Bone marrow is the site of the formation of erythrocytes. Vitamin A is needed in several essential processes in the body, such as metabolism, hematopoiesis, and erythropoiesis; it also regulates cell differentiation and plays a role in the immune system.The approach used in this research is experimental research. Experimental research is research that is carried out by manipulating, and it aims to determine the effect of manipulation on the observed individual's behavior. Manipulation carried out can be in the form of certain situations or actions given to individuals or groups, and after that, the effect can be seen. This experiment was conducted to determine the effects of a treatment given intentionally by the researcher. Giving this treatment is a peculiarity of experimental research compared to other studies. The results showed that there was a significant relationship between giving avocado fruit and improving the nutrition of first-trimester pregnant women, as indicated by the p value of 0.000. This is supported by research data showing that giving avocado fruit increases nutrition more, namely by as much as 70%, while not regularly consuming a lot of avocado fruit does not increase nutrition by 30%.
Effectiveness Of Young Papaya Book Consumption To Increasing Breast Milk Production In Breastfeeding Mothers Hutahayan, Masniar; Herawati, Ita
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 3 (2023): August 2023
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i3.204

Abstract

In 2020 UNICEF reported that the average coverage of exclusive breastfeeding in the world for infants aged 0-6 months only reached 38%. In Indonesia in 2018, the coverage rate for exclusive breastfeeding was 52%, in West Java Province in 2020 the coverage for exclusive breastfeeding for infants was 72.6%. The low coverage of exclusive breastfeeding can be caused by various factors, one of which is the production of breast milk which is not optimal, so that many babies have less nutritional needs because mothers cannot provide maximum breast milk according to the nutritional needs of babies. Breast milk production can be increased by doing complementary therapies, one of which is consuming young papaya stew. To determine the effectiveness of consuming young papaya stew to increase the smooth production of breast milk in nursing mothers. Quasy experiment with one group pretest-posttest design. The sample in this study were all postpartum mothers at PMB Midwife Masniar in November 2022 as many as 30, the sampling technique was total sampling. The smooth distribution of milk production before consuming young papaya stew was mostly substandard 60.0% and after consuming unripe papaya stew most of it was smooth 63.3%. There is an effectiveness of consuming young papaya stew to increase the smooth production of breast milk in nursing mothers (p value 0.000). There is the effectiveness of consuming young papaya stew in increasing the smooth production of breast milk in nursing mothers. It is hoped that midwives can provide midwifery care for postpartum mothers who experience breast milk difficulties by consuming young papaya stew.