Hang Tuah Medical Journal
Hang Tuah Medical Journal: is published by Faculty of medicine, Universitas Hang Tuah with p-ISSN: 1693-1238 e-ISSN: 2598-4861. Its disciplinary focus is medical science and speciality in bio marine science. Hang Tuah Medical Journal is published in English and Indonesia for May and November. Each 90-100 page edition contains between nine and eleven scientific articles on research, case reports and study literature. Contributors of Hang Tuah Medical Journal included: medical researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries. Hang Tuah Medical Journal as the open-access journal has been indexed by SINTA-Science and Technology Index, Garuda, Google scholar Hang Tuah Medical journal has been certificated as a Scientific Journal by Sinta (Science and Technology Index) S5 . valid until Volume 17 No.1, 2017.
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194 Documents
<![CDATA[Pola Penggunaan Bahan Alam sebagai Pengobatan Tambahan Antihipertensi di Puskesmas Pancasan pada Tahun 2024 ]]>
<![CDATA[KALIGIS, CLAUDIA]]>;
<![CDATA[YUNITA, FENNY]]>
<![CDATA[ Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal ]]>
Publisher : <![CDATA[Universitas Hang Tuah ]]>
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DOI: 10.30649/htmj.v23i1.872
<![CDATA[Hypertension is one of the main causes of death rates in Indonesia. This condition is characterized by systolic blood pressure ≥140 mmHg and diastolic ≥90 mmHg. According to WHO, recommended conventional drug therapy includes diuretics, angiotensin receptor blockers (ARB), angiotensin converting enzyme inhibitors (ACEI), and long-acting dihydropyridine calcium channel blockers. A number of studies have shown that several natural ingredients commonly consumed daily have potential as antihypertensives. These natural ingredients include garlic (Allium sativum), celery (Apium graveolens), and cucumber (Cucumis sativus). Based on the 2023 Indonesian Health Survey, the proportion of utilization of traditional health efforts in Indonesia was 32,5% and the proportion of utilization of family medicine gardens (TOGA) was 10%. This study aims to evaluate the pattern of use of natural antihypertensive ingredients in hypertensive patients seeking treatment at the Pancasan Community Health Center in December 2024. The research method was cross-sectional descriptive observation with a total of 110 hypertensive patients as respondents. Data was collected through interviews and filling out questionnaires and presented descriptively. The characteristics of the majority of respondents are women with an age range of 41-50 years and the duration of suffering from hypertension is classified as long term. The research results showed that as many as 106 out of 110 patients consumed natural antihypertensive ingredients. The most widely used natural ingredient is cucumber, namely 36.40%, with the most common method of use being direct consumption.]]>
<![CDATA[Latihan Submaksimal dalam Hiperbarik-Hiperoksia dan Perubahan Fraksi Ejeksi pada Subjek Sehat ]]>
<![CDATA[JOVIE, BENNY]]>;
<![CDATA[PRATIKNYA, DJATIWIDODO EDI]]>;
<![CDATA[KURNIAWAN, I MADE PRASETYA]]>
<![CDATA[ Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal ]]>
Publisher : <![CDATA[Universitas Hang Tuah ]]>
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DOI: 10.30649/htmj.v23i1.875
<![CDATA[Coronary artery disease (CAD) is a leading cause of global morbidity and mortality. An important parameter in assessing left ventricular function is the ejection fraction (EF), which reflects the heart's ability to effectively pump blood into the systemic circulation. In recent decades, hyperbaric oxygen therapy (HBOT) has attracted attention as a non-pharmacological adjunct modality in the management of ischemic heart disease. The type of research is a true experimental research design with a randomized control group pretest - posttest with a sampling technique used is simple random sampling. The population in this study were 30 soldiers from the Surabaya Marine Corps Health Corps. In this experiment in both groups, the results obtained were p<0.05, which means that there is a difference in the pre and post results. When performing submaximal exercise in a hyperbaric-hyperoxic environment, cardiovascular adaptations occur, namely changes in afterload, preload, and myocardial oxygenation. Increased PaO₂ and dissolved oxygen can increase in stroke volume so that LVEF can appear to increase depending on the patient's baseline status. The conclusion of this study shows that submaximal exercise in hyperbaric-hyperoxy conditions provides better results and can even provide results that show normal results.]]>
<![CDATA[Dasar Genetik Kelainan Kromosom pada Kasus Keguguran Berulang ]]>
<![CDATA[AHRIYA DWI AFRIANA]]>;
<![CDATA[HARYA NAROTTAMA]]>;
<![CDATA[EVA DIAH SETIJOWATI]]>;
<![CDATA[HERNI SUPRAPTI]]>;
<![CDATA[RETNO DWI WULANDARI]]>
<![CDATA[ Hang Tuah Medical Journal Vol 23 No 2 (2026): Hang Tuah Medical Journal ]]>
Publisher : <![CDATA[Universitas Hang Tuah ]]>
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DOI: 10.30649/htmj.v23i2.654
<![CDATA[Abstract Recurrent miscarriage (RPL) is defined as the loss of two or more pregnancies before the 24th week of pregnancy. Various factors contribute to RPL, including genetic abnormalities such as chromosomal abnormality. This study aims to ascertain the genetic basis of RPL. This study was an observational descriptive study. Data were collected retrospectively from medical records of patients with RPL at the Medical Genetics Laboratory, Faculty of Medicine, Wijaya Kusuma University Surabaya, from 2014 to 2023. The study population consisted of patients with a history of two to three recurrent miscarriages, with the exception of patients with TORCH infection. The results showed that of the 41 patients who met the inclusion and exclusion criteria, comprise of 17 (89.4%) men and 20 (90.9%) women had normal karyotypes, while 2 (10.4%) men and 2 (9.09%) women showed abnormal karyotypes. The chromosomal abnormalities identified were reciprocal translocation between chromosome (6;13) and heteromorphism on chromosome 9. The results showed the importance of knowing the genetic basis of RPL as a basis for providing genetic counseling.]]>
<![CDATA[The Pengaruh Penyuluhan Kesehatan Penanganan Scabies (Sarcoptes Scabiei) Terhadap Tingkat Pengetahuan Swamedikasi Santri Pondok Pesantren Darussalam : Pengaruh Penyuluhan Kesehatan Penanganan Scabies (Sarcoptes Scabiei) Terhadap Tingkat Pengetahuan Swamedikasi Santri Pondok Pesantren Darussalam ]]>
<![CDATA[NABILA RADIAHAYYA]]>;
<![CDATA[FAUZIAH]]>;
<![CDATA[SILMA KAAFFAH]]>
<![CDATA[ Hang Tuah Medical Journal Vol 23 No 2 (2026): Hang Tuah Medical Journal ]]>
Publisher : <![CDATA[Universitas Hang Tuah ]]>
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DOI: 10.30649/htmj.v23i2.822
<![CDATA[Scabies is a skin disease caused by the Sarcoptes scabiei mite, and is often suffered by individuals who live in groups such as dormitories, Islamic boarding schools, densely populated housing. Knowledge plays an important role in handling the transmission of scabies by practicing personal hygiene or by self-medication. This study aims to determine the level of knowledge of sel-medication in handling scabies in student at Islamic Boarding School in Purwokerto. The study was conduxted using a uestionnaire that had been tasted for validity and reliability through a one group pre-post design approach, which was conducted in march 2024 using a systematic random sampling technique and a sample of 55 students was obtained. Based on the results of the Cronbach alpha reliability test were reliable. The results of the univariate analysis showed that the majority of respondents were aged 15-20 years and female. The results of the bivariate anaysis of the Wilcoxon test showed that the level of khowledge of students before and after the intervention increased significantly (p-value < 0.05), namely from the good category of 61.8% to 89.1% and the sufficient category from 38.2% to 10.9%. in conclusion, periodic education is needed to provide information to student so that students’ knowledge increases further. Keywords : level of khowledge, scabies, pre-post, questionnaire, systematic random sampling]]>
<![CDATA[PENGARUH EKSTRAK KULIT BATANG Rhizophora apiculata TERHADAP KADAR GLUKOSA DARAH Rattus norvegicus YANG DIINDUKSI DEKSAMETASON ]]>
<![CDATA[ARLISA NABILA LARASATI]]>;
<![CDATA[FITRI HANDAJANI]]>;
<![CDATA[SAPTONO PUTRO]]>;
<![CDATA[INTAN KOMALASARI]]>
<![CDATA[ Hang Tuah Medical Journal Vol 23 No 2 (2026): Hang Tuah Medical Journal ]]>
Publisher : <![CDATA[Universitas Hang Tuah ]]>
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DOI: 10.30649/htmj.v23i2.874
<![CDATA[Background: Dexamethasone is a glucocorticoid, if used long term it can cause increased oxidative stress and hyperglycemia. In diabetes patients, large amounts of antioxidants are needed as an antidote to free radicals in the body. Ethanol extract of Rhizophora apiculata stem bark has antioxidant and antidiabetic activity. Objective: This study aims to evaluate the effect of ethanol extract of Rhizophora apiculata bark on the blood glucose levels of white rats induced by dexamethasone. Methods: This research use 32 rats grouped into 4 groups. G (-), standard feed, G (+) induced by dexamethasone, GP 1 bark extraxt and induced by dexamethasone at the same time as giving mangrove bark extract, and DT 2, dexamethasone and mangrove bark extract, then on the 22nd day a blood sample was taken to measure blood glucose levels. Results: the average blood glucose level G- = 146.5; G+= 213.375; GP = 185.875; GT = 244.375. In the One Way Anova parametric test, significant results were obtained, 0.015 (p<0.05). Then in the Post Hoc LSD test; G- and G+ had a significance of 0.028 (p<0.05), while the G+ and GP and GT groups did not show significant differences. Conclusion: Subcutaneous dexamethasone induction treatment was proven to increase blood glucose levels in male Rattus norvegicus. Administration of ethanol extract of Rhizophora apiculata stem bark as prophylaxis or therapy was unable to reduce blood glucose levels of male Rattus norvegicus induced by dexamethasone.]]>
<![CDATA[Hubungan Hipertensi dengan Kejadian Sindrom Koroner Akut: Studi Kasus–Kontrol ]]>
<![CDATA[MADE BAGUS MANIK SATRIA MAHOTTAMA]]>;
<![CDATA[KADEK SURYA ATMAJA]]>;
<![CDATA[SRI MASYENI]]>;
<![CDATA[SAKTIVI HARKITASARI]]>;
<![CDATA[ADITYA YUDISTIRA]]>
<![CDATA[ Hang Tuah Medical Journal Vol 23 No 2 (2026): Hang Tuah Medical Journal ]]>
Publisher : <![CDATA[Universitas Hang Tuah ]]>
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DOI: 10.30649/htmj.v23i2.896
<![CDATA[Abstract Background: Acute Coronary Syndrome (ACS) is a major cardiovascular emergency associated with substantial morbidity and mortality. Hypertension is considered an important risk factor, yet local evidence remains essential. Objective: evaluate the relationship between hypertension and ACS occurrence in two referral hospitals in Bali, Indonesia. Methods: A hospital-based case–control study using medical record data was conducted at Karangasem and Tabanan District Hospitals. A total of 176 subjects were included: 88 ACS cases and 88 non-ACS controls. Purposive sampling with age- and sex-matching was applied. Bivariate analysis employed Chi-square test, reporting OR with 95% CI. Results: Most participants were aged >45 years (96.6%) and male (65.9%). Among cases, the most frequent ACS subtype was unstable angina (43.2%), followed by NSTEMI (34.1%) and STEMI (22.7%). The most common presenting symptoms were dyspnea (84.1%) and typical chest pain (79.5%). Hypertension was present in 39.8% of cases and 18.2% of controls. Hypertension was significantly related to ACS (p=0.002 OR of 2.97; 95% CI: 1.491–5.923).Conclusion: Hypertension is significantly related to ACS occurrence and increases the odds of ACS by nearly threefold.]]>
<![CDATA[Perbandingan Tingkat Terendah Trombosit antara Pasien Demam Dengue dan Demam Berdarah Dengue ]]>
<![CDATA[WISNU TRANAYA PUTRA]]>;
<![CDATA[SRI MASYENI]]>;
<![CDATA[KOMANG TRISNA SUMADEWI]]>;
<![CDATA[SARASWATI LAKSMI DEWI]]>
<![CDATA[ Hang Tuah Medical Journal Vol 23 No 2 (2026): Hang Tuah Medical Journal ]]>
Publisher : <![CDATA[Universitas Hang Tuah ]]>
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DOI: 10.30649/htmj.v23i2.963
<![CDATA[Background: Dengue infection remains a major public health problem and is frequently accompanied by thrombocytopenia. The lowest platelet level during illness (thrombocyte nadir) may reflect clinical severity and assist in early risk stratification. Objective: To compare the mean thrombocyte nadir between patients with dengue fever (DF) and dengue hemorrhagic fever (DHF). Methods: A cross-sectional study was conducted using medical record data of 150 hospitalized dengue patients at Sanjiwani Hospital (2022–2024). Dengue was confirmed by IgM anti-dengue testing or NS1 antigen detection. DHF was defined as a ≥20% increase in hematocrit at admission. Patients with a history of idiopathic thrombocytopenic purpura were excluded. Demographic and clinical data were summarized descriptively, and differences in thrombocyte nadir between DF and DHF were analyzed statistically. Results: Of 150 patients, 119 (79.3%) had DF and 31 (20.7%) had DHF. The thrombocyte nadir differed significantly between groups, with DHF demonstrating a lower nadir than DF (p = 0.001). Conclusion: Thrombocyte nadir is significantly lower in DHF compared with DF, supporting the usefulness of serial platelet monitoring to aid severity assessment and clinical surveillance in hospitalized dengue patients.]]>
<![CDATA[Therapeutic Plasma Exchange pada Pasien dengan Sindrom Guillain–Barré ]]>
<![CDATA[EVANS P. BIASA]]>;
<![CDATA[MORDEKHAI L. LAIHAD]]>;
<![CDATA[BARRY I. KAMBEY]]>
<![CDATA[ Hang Tuah Medical Journal Vol 23 No 2 (2026): Hang Tuah Medical Journal ]]>
Publisher : <![CDATA[Universitas Hang Tuah ]]>
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DOI: 10.30649/htmj.v23i2.967
<![CDATA[Abstract Guillain–Barré Syndrome (GBS) is an acute autoimmune neuropathy that may rapidly progress to severe weakness and respiratory failure. Therapeutic plasma exchange (TPE) is a recommended immunomodulatory therapy, particularly in patients with severe clinical manifestations. Case Report: We report a 64-year-old female presenting with rapidly progressive quadriparesis requiring intensive care and mechanical ventilation. Nerve conduction studies confirmed Guillain–Barré Syndrome, Acute Motor and Sensory Axonal Neuropathy (AMSAN) subtype. The patient underwent four cycles of therapeutic plasma exchange. Although standard protocols generally recommend five cycles, treatment was discontinued earlier due to significant clinical improvement. Discussion: Following TPE, the patient demonstrated gradual clinical improvement, including hemodynamic stabilization, reduced ventilatory support, and successful extubation. This rapid clinical response supports an individualized approach to determining the number of TPE cycles based on continuous clinical evaluation, particularly in critically ill patients in the intensive care unit. Therapeutic plasma exchange may serve as an important immunomodulatory therapy in patients with severe Guillain–Barré Syndrome. Individualizing the number of TPE cycles based on clinical response can be considered in clinical practice without strict adherence to standard protocols. This case highlights that serial clinical evaluations may serve as a basis for considering individualized TPE cycle numbers in severely ill GBS patients in the intensive care unit.]]>
<![CDATA[Profil Tajam Penglihatan Pengendara Ojek Online di Kelurahan Keputih Surabaya ]]>
<![CDATA[VEYSHA IZDIHAR]]>;
<![CDATA[WILLIAM SAYOGO]]>;
<![CDATA[VICTOR SETIAWAN TANDEAN]]>
<![CDATA[ Hang Tuah Medical Journal Vol 23 No 2 (2026): Hang Tuah Medical Journal ]]>
Publisher : <![CDATA[Universitas Hang Tuah ]]>
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DOI: 10.30649/htmj.v23i2.971
<![CDATA[Visual acuity is an important factor influencing driving safety, particularly among online motorcycle taxi drivers who work with high visual exposure and varying road conditions. Visual acuity plays a critical role in driver’s ability to detect road hazards, interpret traffic signs, and respond to dynamic traffic situations. Because online motorcycle taxi drivers frequently operate for extended hours which they are exposed to sunlight, glare, dust, wind, and prolonged screen use when interacting with customers and navigation applications which can affect eye comfort and performance. These occupational stressors may contribute to reduced visual efficiency, emphasizing the importance of regular monitoring. This study aims to determine the visual acuity profile of online motorcycle taxi drivers in Keputih Surabaya subdistrict. A descriptive observational design with a cross-sectional approach was used, involving 70 respondents. Visual acuity was examined using a Snellen chart and pinhole test and classified according to the World Health Organization standards. The results showed that 34 respondents (48.57%) had refractive errors, 27 respondents (38.57%) had normal visual acuity, and 9 respondents (12.86%) had non-refractive visual impairments. The majority of respondents with refractive errors remained within the normal visual acuity category (85.29%).]]>
<![CDATA[Pengaruh Pemberian Makanan Tambahan Kacang Hijau dan Ikan Lele terhadap Berat Badan Balita Underweight ]]>
<![CDATA[DANIA SAFA'ATIN AINI]]>;
<![CDATA[WIDIA SHOFA ILMIAH]]>;
<![CDATA[ANIK SRI PURWANTI]]>
<![CDATA[ Hang Tuah Medical Journal Vol 23 No 2 (2026): Hang Tuah Medical Journal ]]>
Publisher : <![CDATA[Universitas Hang Tuah ]]>
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DOI: 10.30649/htmj.v23i2.973
<![CDATA[Underweight in children aged 1–5 years can hinder growth and development. Children with a weight-for-age Z-score (WAZ) < -2 SD are classified as underweight by WHO and require nutritional intervention. Supplementary feeding (PMT) based on local food with high protein and energy content can improve nutritional status. This quasi-experimental study employed a pretest–posttest control group design involving 32 children at Posyandu Balai Desa Sumberagung, divided into 16 intervention and 16 control participants. The intervention group received PMT made from mung bean and catfish for 30 days, while the control group received routine Posyandu services. Researchers did not directly observe children consuming PMT but relied on parental reports. Body weight was measured before and after the intervention and analyzed using Paired Sample T-Test and Independent Sample T-Test (α=0.05). Results showed the mean WAZ of the intervention group increased from -2.47 to -1.85 (p=0.000), whereas the control group increased from -2.46 to -2.33 (p=0.006). The difference between groups was significant (p=0.003). PMT made from mung beans and catfish significantly improved children’s weight. Study limitations include small sample size, short intervention duration, and reliance on parental reporting. Future studies are recommended to include larger samples, longer interventions, direct observation of consumption, and consider dietary patterns, health status, and variations of local food preparations.]]>
