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Hang Tuah Medical Journal
Published by Universitas Hang Tuah
ISSN : 16931238     EISSN : 25984861     DOI : https://doi.org/10.30649/htmj.v19i2
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Hang Tuah Medical Journal: is published by Faculty of medicine, Universitas Hang Tuah with p-ISSN: 1693-1238 e-ISSN: 2598-4861. Its disciplinary focus is medical science and speciality in bio marine science. Hang Tuah Medical Journal is published in English and Indonesia for May and November. Each 90-100 page edition contains between nine and eleven scientific articles on research, case reports and study literature. Contributors of Hang Tuah Medical Journal included: medical researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries. Hang Tuah Medical Journal as the open-access journal has been indexed by SINTA-Science and Technology Index, Garuda, Google scholar Hang Tuah Medical journal has been certificated as a Scientific Journal by Sinta (Science and Technology Index) S5 . valid until Volume 17 No.1, 2017.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 172 Documents
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Pengaruh Pandemi COVID-19 Terhadap Nilai Biologi Mahasiswa Semester Satu Fakultas Kedokteran Universitas Hang Tuah LILIAWANTI, LILIAWANTI; GUNAWAN TANDEAN, PETER; ARUNDNI, PRIMA
Hang Tuah Medical Journal Vol 22 No 2 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v22i2.813

Abstract

The COVID-19 pandemic has also had a significant impact on the education sector. The policy requires all activities carried out outside the home, including teaching and learning activities, to be stopped until the COVID-19 pandemic subsides. The change from face-to-face to online learning systems brings a number of problems that are challenges for the world of education. To determine the effect of the COVID-19 pandemic on the biology grades of first semester students of the UHT Faculty of Medicine in the 2017/2018, 2018/2019 and 2020/2021, 2021/2022 academic years. This study will use the cross-sectional group design method. This study used all first semester students of the Faculty of Medicine, Hang Tuah University, batch 2017/2018, 2018/2019 and 2020/2021, 2021/2022. RESULTS: In CBT, the results of the T test were obtained with insignificant results for the Biology scores of first semester students of the UHT Medical Faculty during the non-pandemic period of 2017/2018 with the pandemic period of 2020/2021 with p = 0.0085 (p ˂ 0.05). In SOOCA with the T test, the results were obtained with insignificant results for the Biology scores of first semester students of the UHT Medical Faculty during the non-pandemic period of 2017/2018 with the pandemic period of 2020/2021 with p = 0.078 (p ˂ 0.05). and Final Value with T-test obtained insignificant results of the Biology value of first semester FK UHT students during the non-pandemic period 2017/2018 with the pandemic period 2020/2021 with p = 0.054 (p ˂ 0.05). In CBT, the results of the T-test were obtained with significant results of the Biology value of first semester FK UHT students during the non-pandemic period 2017/2018 with the pandemic period 2021/2022 and 2021/2022 with p = 0.000 (p ˂ 0.05). ). In SOOCA and Final Value with T-test, significant results were obtained of the Biology value of first semester FK UHT students during the non-pandemic period 2018/2019 with the pandemic period 2021/2022 with p = 0.000 (p ˂ 0.05). In CBT, the results of the one-way ANOVA test were obtained with significant results for the Biology scores of first-semester FK UHT students during the 2018/2019 non-pandemic period with the 2020/2021 and 2021/2022 pandemic periods with p = 0.000 (p ˂ 0.05). In SOOCA and Final Scores with the T-test, significant results were obtained for the Biology scores of first-semester FK UHT students during the 2018/2019 non-pandemic period with the 2020/2021 and 2021/2022 pandemic periods with p = 0.000 (p ˂ 0.05). In the pre-pandemic academic year 2017/2018 and the pandemic academic year 2020/2021, there was a difference in the average CBT, SOOCA, and Final Scores for biology of first-semester FK UHT students. In the academic year before the pandemic 2017/2018 and the academic year during the pandemic 2021/2022, there was a difference in the average CBT, SOOCA, and Final Biology Scores of first-semester FK UHT students. In the academic year before the pandemic 2018/2019 and the academic years during the pandemic 2020/2021 and 2021/2022, there was a difference in the average CBT, SOOCA, and Final Biology Scores of first-semester FK UHT students. Keywords:
Metaplasia Myelofibrosis WIJAYANINGRUM, LENA; I DEWA MADE WIDI HERSANA; I KETUT TIRKA NANDAKA
Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v23i1.662

Abstract

Background: Myelofibrosis with myeloid metaplasia is a rare myeloproliferative disorder. Epidemiological data on the incidence of Myelofibrosis with myeloid metaplasia are still lacking. In Goteborg, Sweden, from 1983 to 1992, the incidence of the disease was retrospectively calculated at 0.4 per 100,000 population. In population- based leukemia data in the UK, the incidence of Myelofibrosis with myeloid metaplasia is estimated to be 0.73 per 100,000 person-years in men and 0.40 per 100,000 person-years in women. It is estimated that there are 230 new cases each year in England and Wales, 330 in Italy, and 1,600 in the United States. No medical therapies have been shown to be effective against the overall survival of patients. The prognosis of myelofibrosis with myeloid metaplasia varies widely. For this reason, it is necessary to report cases of Myelofibrosis Myeloid Metaplasia Methode: Descriptive research, in the form of case reports of patients with myelofibrosis metaplasia, with data obtained from primary data anamnesa and direct physical examination of patients and secondary data from medical records, the results of examinations of doctors at RSPAL Dr Ramelan Surabaya 2022-2024. Results: Since 13 December 2022 until this date 3 May 2024 (17 months).Patient with a diagnosis of Primary Myelofibrosis and high Uric Acid after undergoing therapy with jakavi 15 mg 1x1. Allopurinol 300mg 1x1 and Nabic 3x1. Experienced improvement in complaints of increased appetite. Resting at night there are no complaints. Activity such as walking is not easily tired, mass in the abdomen that does not cause pain. On physical examination, there was an increase in body weight from 50 kg to 55 kg and still found S IV splenomegaly, from the haematological examination there was a decrease in platelets 136.00 (10^3µL) which was previously 203.00 (10^3µL). Uric acid improved from 10.8 mg/dl to 7.7 mg/dl. Conclusion: Jakavi is a drug containing ruxolitinib that can treat splenomegaly or disease-related symptoms in adult patients with myelofibrosis. Keywords: Myelofibrosis Metaplasia.Splenomegaly.Jakavi
Karakteristik dan Faktor Risiko Pasien Kanker Kulit Di Rspal Dr. Ramelan Surabaya Periode Januari 2021-Desember 2023 HIBATULLAH, HISYAM; OCTAVIANDA, YOHANA; RAHAYU, INDRI NGESTI; MUTIADESI, WAHYU PRASASTI
Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v23i1.771

Abstract

Skin cancer is one of the most common types of cancer diagnosed worldwide. The incidence and mortality rates of skin cancer have also continued to increase in recent decades. In Indonesia, skin cancer is the cancer with the third highest incidence after uterine cancer and breast cancer. The purpose of this study was to determine the characteristics and risk factors of skin cancer patients at RSPAL dr. Ramelan Surabaya for the period January 2021-December 2023. Using a qualitative descriptive approach with variables in the form of secondary data that has been recorded in the medical records of skin cancer patients at RSPAL dr. Ramelan Surabaya for the period January 2021-December 2023. The data examined were the type of skin cancer, symptoms of skin cancer, location of skin cancer, patient age, and patient gender. The most characteristic type of skin cancer is Basal Cell Carcinoma in 51 cases. The most characteristic symptom of skin cancer was the formation of new moles/bumps in 67 cases. The characteristic of the location of skin cancer is mostly on the head in 69 cases. The age characteristics of cancer patients were most common in elderly patients at 56 cases. The sex characteristics of skin cancer patients were mostly female at 51 cases. The occupational characteristics of skin cancer patients were mostly indoor workers at 86 cases. Most cases were of the BCC type, with the most common symptom being the formation of new moles.
Hubungan antara Tingkat Pengetahuan tentang Kanker Serviks dan Hasil Pap Smear pada Wanita Dewasa DIGAMBIRO, REZA ADITYA; ILONA, FLORINDA; CHENDRASARI, JULIAN; SETYANINGRUM, DYAH AYU WORO; LESTARI, INDAH WIDYA
Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v23i1.809

Abstract

Cervical cancer can arise from a persistent infection with Human Papillomavirus (HPV), which can be avoided through early detection by pap smear screening. Having adequate knowledge about cervical cancer is crucial for encouraging participation in pap smear tests, which can detect non-cancerous or precancerous changes before they progress. This cross-sectional descriptive-analytic study aimed to assess knowledge levels about cervical cancer and their correlation with pap smear results among women of reproductive age in Jakarta, Bogor, and Bekasi (23–50 years). A total of 133 participants underwent a structured questionnaire for assessing knowledge and a pap smear test for evaluating cervical health. The pap smear results showed that 80% were normal, 6% had atypical cells without malignancy, and 14% showed inflammatory lesions. A Chi-square test revealed a significant association between knowledge levels and pap smear outcomes. These findings provide valuable insights for healthcare stakeholders to develop effective health promotion strategies that increase pap smear coverage and encourage early detection of cervical cancer.
Korelasi Perilaku Personal Hygiene Remaja Putri Di Sma Budi Mulia Jakarta Pusat Pada Kejadian Keputihan TAY, JOCELYN; RUSLIM, WELLY HARTONO
Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v23i1.832

Abstract

The issue of vaginal discharge among adolescent girls is a significant concern in tropical dan humid countries like Indonesia. Approximately 45% of women in Indonesia experience reccurent vaginal discharge yet, several adolescents still perceive it as a normal condition. This research intends to investigate the connection between hygiene practices and occurrences of vaginal discharge among female students at Budi Mulia Senior High School in Central Jakarta. This analysis adopted a cross-sectional design use an observational approach, involving 146 female respondents, and was conducted from January to February 2025. Data collection utilized a questionnaire and chi-square analysis, revealing that 58,2% maintained excellent personal hygiene, while 50% experienced pathological vaginal discharge. The research indicated a strong link between hygiene practices and vaginal discharge incidence, with a p-value of 0,016.
Studi Retrospektif Karakteristik Pasien Kista Ovarium di RSUD Kota Bogor Periode 2020-2024 ANDRIANSYAH, NADIA FAZILA; RUSLIM, WELLY HARTONO
Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v23i1.836

Abstract

An ovarian cyst is a fluid-filled sac that develops in the ovary. There are two types of lesions which are neoplastic and non neoplastic. The formation of ovarian cysts is affected by hormonal imbalances during puberty and menopause. The purpose of this study is to know the characteristics of ovarian cyst patients at RSUD Kota Bogor for the 2020-2024 period. This study used a total sampling method. The subjects of the study were patients with the diagnosis of ovarian cysts based on biopsy and resection and histopathological examinations listed in the medical records of Bogor City Hospital. In this study, 122 medical records of patients with the majority of patients were between the ages of 40-49 (30,3%) and dominated by married women (82,8%). The characteristics of ovarian cysts are found to be benign histopathological criteria (86,9%). The most common non neoplastic (53,3%) ovarian cyst found is endometriosis (50,8%). The most common neoplastic (46,7%) ovarian cyst found is benign teratoma (28,1%). The most common characteristics were found in 40–49 years of age, with marital status, benign histopathological criteria where endometriosis cyst and mature teratoma as the dominant non-neoplastic and neoplastic cyst.
Faktor-Faktor yang Berpengaruh Terhadap Keparahan Infeksi Dengue pada Anak: English PUTU AYUNDA TRISNIA; SARASWATI LAKSMI DEWI; SRI MASYENI
Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v23i1.844

Abstract

Dengue infection is one of the significant global health problems, especially in children. This paper aims to identify factors that affect the severity of dengue infection in the child population. The factors analysed included age, infection status, obesity, viral genome and Ns1 protein titers of dengue. Children who are younger and have an obese nutritional status tend to experience more severe symptoms. In addition, high NS1 titers, viral genomes, and secondary infections also contribute to a higher risk of infection. Detecting warning signs is important because it can be used as a predictor of more severe dengue infection.
Manajemen Komplikasi Nontrombotik Intradialitik pada Pasien Penyakit Ginjal Kronis DEWI, SARASWATI LAKSMI
Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v23i1.852

Abstract

Management of intradialytic nonthrombotic complications in patients with chronic kidney disease is an essential aspect of hemodialysis care. These complications, such as hypotension, hypertension, DDS, muscle cramps, nausea and itching, can have a significant effect on the patient's well-being. Effective treatment requires a multidisciplinary approach that involves the medical team, patient education, and close monitoring during dialysis sessions. Effective protocols, including fluid volume regulation and the proper use of medications, play a crucial role in reducing the frequency and severity of complications. With the right management strategy, it is hoped that the quality of life of patients can be improved, and the morbidity rate associated with intradialytic nonthrombotic complications can be minimised. Further research is needed to optimise clinical practice and enhance the understanding of these complications.
Profil Nilai Laju Endap Darah (Led) Pada Pasien Tuberkulosis Dewasa Di Rsud Waled Periode 2022-2023 APRILIANINGTYAS, NUR ADILLA; NOVIANI, ISTI; SEDAYU
Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v23i1.864

Abstract

Background: Tuberculosis (TB) is an infectious illness directly caused by Mycobacterium tuberculosis. Primarily, they impact the lungs (pulmonary tuberculosis), but they can also include other bodily organs (extrapulmonary tuberculosis). The erythrocyte sedimentation rate (ESR) test is a standard blood examination. The erythrocyte sedimentation rate measures the sedimentation velocity of erythrocytes in unclotted blood, expressed in mm/hour. During acute inflammation and infections, both acute and chronic, the erythrocyte sedimentation rate (ESR) may rise over its usual range. Objective: To acquire a comprehensive understanding of the erythrocyte sedimentation rate (ESR) in adult tuberculosis patients throughout Cirebon Regency. Methods: This study is a descriptive observational analysis carried out at Waled Hospital in Cirebon Regency. A research sample of 148 patients was acquired by complete sampling methodology utilizing secondary data from medical records. The data underwent univariate analysis. Results: Univariate analysis revealed that among 145 tuberculosis patients aged ≥18 years, 85 (58.6%) were male, whereas 60 (41.4%) were female. Out of 145 TB patients, 137 (94.5%) had pulmonary TB, while 8 (5.5%) had extrapulmonary TB. Additionally, 133 patients (91.7%) exhibited an elevation in erythrocyte sedimentation rate (ESR), with a minimum value of 4 mm/hour and a maximum of 140 mm/hour. Conclusion: Tuberculosis cases in individuals aged 18 years and older are predominantly male, with the highest incidence being pulmonary tuberculosis and an elevation in erythrocyte sedimentation rate (ESR).
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Rhizophora mucronata terhadap Shigella dysenteriae NUGRAHA, MUHAMMAD FIKRY; ARDIANA, DIAN; ASAMI RIETTA KUMALA; NITA PRANITASARI
Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v23i1.870

Abstract

Shigella dysenteriae is the most common cause of diarrhea in cases of shigellosis. This bacterium can invade the epithelium of the large intestine, ileum, and rectum, causing diarrhea accompanied by blood and mucus. Effective antibiotic therapy for this disease has shown resistance. The mangrove Rhizophora mucronata contains various secondary metabolites that have the potential to be new antibacterial alternatives. This study is an in vitro laboratory study to determine the inhibitory effect of Rhizophora mucronata leaf extract on the growth of Shigella dysenteriae bacteria. The study used the Kirby-Bauer drop diffusion method with Mueller-Hinton Agar medium and a digital caliper to measure the diameter of the inhibition zone. Twenty-four samples were divided into six groups: negative control (bacterial culture treated with distilled water); treatment groups (Kp) (treated with extract concentrations of 25%, 50%, 75%, and 100%); and positive control (treated with ciprofloxacin 5 mcg). Results: The negative control group and all treatment groups had an average inhibition zone of 6.00 mm or no inhibition zone, while the positive control group had an average of 25.845 mm. The Kruskal-Wallis test (p=0.0001) showed significant differences among the tested groups, and the post hoc test (p=0.014) indicated significant differences between the positive control group and all other groups. The leaf extract of Rhizophora mucronata was not found to have inhibitory activity against the growth of Shigella dysenteriae.-

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