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Divisi Gastroenterologi, Departemen Ilmu Penyakit Dalam, FKUI/RSUPN Dr. Cipto Mangunkusumo, Jl. Diponegoro No. 71 Jakarta 10430 Indonesia
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INDONESIA
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Published by The Indonesian Society for Digestive Endoscopy
ISSN : 14114801     EISSN : 23028181     DOI : -
Core Subject : Health,
Medicine & Pharmacology
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy is an academic journal which has been published since 2000 and owned by 3 Societies: The Indonesian Society of Gastroenterology; Indonesian Association for the Study of the Liver; The Indonesian Society for Digestive Endoscopy. The aim of our journal is to advance knowledge in Gastroenterology, Hepatology, and Digestive Endoscopy fields. We welcome authors for original articles, review articles, and case reports in the fields of Gastroenterology, Hepatology, and Digestive Endoscopy.
Arjuna Subject : Kedokteran - Ilmu Pencernaan
Articles 771 Documents
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Post-Endoscopic Retrograde Cholangiopancreatography Complications at Dr. Cipto Mangunkusumo General Hospital Rolan Sitompul; Achmad Fauzi; Dadang Makmun; Murdani Abdulah; Ari Fahrial Syam; Marcellus Simadibrata
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 10, ISSUE 2, August 2009
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/102200941-45

Abstract

Background: This study retrospectively evaluated post-endoscopic retrograde cholangiopancreatography (ERCP) complications at Cipto Mangunkusumo hospital in order to improve management of a subsequent prospective study of post-ERCP complications.Method: The indications, findings, diagnostic or therapeutic procedure, cannulation, devices used during the procedure, and complications of patients treated consecutively with ERCP between January 2004 and November 2008 were evaluated retrospectively.Results: Of 176 ERCP patients who were initially evaluated, 38% had undergone diagnostic ERCP and 62% therapeutic ERCP. The median age of the patients was 49 years (range 18–80 years); 95 (53.9%) were male. Only 54 of these 176 procedures could be evaluated for post-ERCP complications. A computed tomographic abdominal scan or magnetic resonance cholangio-pancreatography was performed in 23 (42.6%) patients and a biliary sphincterotomy in 14 (25.9%) patients. The overall complication rate was 33.3%: 14.8% after diagnostic ERCP and 18.5% after therapeutic ERCP. The complications after diagnostic ERCP were pancreatitis in 3 (15%) patients, cholangitis in 3 (15%) patients, hemorrhage in 1 (5%) patient, pancreatitis and hemorrhage in 1 (5%) patient; the complications after therapeutic ERCP were pancreatitis in 6 (17.6%) patients, cholangitis in 3 (8.8%) patients, hemorrhage in none, and concomitant pancreatitis with hemorrhage in 1 (2.9%) patient. No significant difference was observed between the complication rates and the type of ERCP performed.Conclusion: There were no differences in the complications after diagnostic and therapeutic ERCP. As our study shows the post-ERCP complication rate to be higher than those of other large retrospective and prospective studies, we must evaluate it in a prospective study.Keywords: post-ERCP, complications, therapeutic ERCP, diagnostic ERCP
Demographic Characteristic of Fundic Gland Polyp and Its Association with Gastritis in Pathology Anatomy Department, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital Liza Handayani; Ening Krisnuhoni
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 18, No 1 (2017): VOLUME 18, NUMBER 1, April 2017
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1653.011 KB) | DOI: 10.24871/181201725-29

Abstract

Background: Fundic gland polyp (FGP) is the most common polyp found in the stomach with the incidence of 47% from all stomach polyps. FGP is more common to be found in female with the ratio of 5:1 and occurs in the average age of 53-year-old. Gastrin is a hormone produced by G cell, which function is to facilitate epithelial cell proliferation. Gastritis is a frequently found digestive tract disturbance. Torbenson et al showed the presence of chronic gastritis in FGP patients. The aim of this study is to observe the demographic characteristics of FGP and to identify the association between number of polyps with morphologic appearances of gastritis in Anatomical Pathology Department, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital in year 2012-2014.Method: This retrospective study was a descriptive analytical study. This study was performed by reviewing the slides of FGP cases and evaluating the severity of gastritis based on visual analog scale from Sydney System (SS).Results: Study of FGP demographic obtained 44 cases with predominantly female aged 30 (68.2%), patients’ average age was 55.4 year old with dominant age group in age group 51-60 year old which accounted for 16 (36.4%).  This study was performed in 38 cases. The frequency of single polyp was 18 and multiple polyp was 20. Most cases were chronic inflammation which accounted for 21 (55.3%) and mild atrophy 18 (47.4%). Mild intestinal metaplasia was found in 1 case. There was no case of neutrophil infiltration, H. pylori infection or dysplasia. Chi-square test revealed that there was no significant association between number of polyps with gastritis.Conclusion: Chi-square test which was performed in this study showed there is no significant association between number of polyps with gastritis.
Non-Surgical Biliary Drainage on Biliary Obstruction due to Malignancy Evy Yunihastuti; L A Lesmana; Ari Fahrial Syam; Irsan Hasan; Karmel Tambunan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 2, NUMBER 2, August 2001
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2220018-20

Abstract

Surgery is still the golden standard of curative therapy for malignant biliary obstruction, but only 10- 20% of cases considered resectable. Therefore, palliative therapy to relieve pain, cholestasis, and biliary obstruction, is the main treatment for most patients. The development of percutaneous transhepatic biliary drainage and endoscopic biliary drainage had brought about minimally invasive treatment for malignant biliary obstruction, which had lower morbidity and mortality than surgical drainage. The choice of drainage technique depends on type of tumor, site of obstruction, also the available expert and instrumentation.    Keywords: malignant  biliary  obstruction,  percutaneous  transhepatic  biliary  drainage, therapeutic endoscopic retrograde cholangiopancreatography
Cost Effectiveness and Efficiency of Reusing Single-use Medical Devices Aan Santi; Risa Ismadewi; TR Fitriyani; Murdani Abdullah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 15, No 1 (2014): VOLUME 15, NUMBER 1, April 2014
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5050.717 KB) | DOI: 10.24871/151201425-30

Abstract

Background: Reusing single-use medical devices is a very important and complicated process since theimplementation requires both operational and technical skills, even for professional users. The aim of our studywas to determine the cost effectiveness and efficiency of reusing single-use medical devices. Method: The study was a cross-sectional study conducted between July and December 2013. It compared twogroups of patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) examination at the Digestive Endoscopy Center, Cipto Mangunkusumo Hospital, Jakarta. Patients in the first group received new single-use medical devices; while patients in the other group received the re-used single-use medical devices.Reprocessing for reusing single-used medical devices was conducted according to standard procedures ofdecontamination and sterilization. Results: Reusing medical devices were more commonly found (50.9%) in ERCP procedures than usingnew medical devices (49.1%). There was no significant difference on operator satisfaction between using there-used and new medical devices (p = 0.062). There was lower average cost for reusing medical devices thanusing new medical devices (IDR 198,818,250.00 vs. IDR 594,354,000.00; p = 0.000); percentage of successrate for reusing was lower than new medical devices (80% vs. 90,6%; p = 0.203). There was also no significantdifference regarding the negative impacts such as fever or infection of reusing medical devices compared tousing new medical devices (p = 0.676). Conclusion: This study has shown good effectiveness in terms of operator satisfaction, success rate andimpacts on patients. The cost for reusing medical devices is more efficient than using new medical devices.Keywords: effectiveness, efficiency, reusing medical devices, new, endoscopy ABSTRAKLatar belakang: Penggunaan alat medis sekali pakai (single-use) yang dipakai kembali (re-use) menjadi sangat penting dan kompleks dalam menerapkan kemampuan operasional dan teknik pada profesional penggunaalat tersebut. Tujuan penelitian ini adalah untuk menilai efektifitas biaya dan efisiensi penggunaan perangkatmedis single-use yang dijadikan re-use. Metode: Penelitian ini merupakan penelitian potong lintang dilakukan pada Juli hingga Desember2013. Penelitian membandingkan dua kelompok pasien yang menjalani pemeriksaan endoscopic retrogradecholangiopancreatography (ERCP) di Pusat Endoskopi Saluran Cerna (PESC), Rumah Sakit CiptoMangunkusumo, Jakarta. Pasien pada kelompok pertama menerima tindakan dengan alat medis baru; sedangkanpasien di grup lainnya menerima tindakan dengan alat medis re-use. Proses penggunaan alat medis re-use dilakukan sesuai dengan prosedur dekontaminasi dan sterilisasi yang berlaku. Hasil: Penggunaan alat medis dalam tindakan ERCP lebih banyak menggunakan alat re-use (50,9%) dibandingkan alat baru (49,1%); kepuasan operator pada alat re-use maupun alat baru tidak berbeda secarasignifikan (p = 0,062); rata-rata biaya pada penggunaan alat re-use lebih rendah dibandingkan pada alat baru (Rp 198.818.250,00 vs. Rp 594.354.000,00; p = 0.000); persentase keberhasilan penggunaan alat re-use lebihrendah dibandingkan pada alat baru (80% vs. 90,6%; p = 0,203); dampak berupa terjadi demam atau infeksipada penggunaan alat re-use dan alat baru tidak menunjukkan perbedaan yang signifikan (p = 0,676). Simpulan: Penggunaan alat re-use menunjukkan efektifitas yang baik pada kepuasan operator, keberhasilanalat, dan dampak pada pasien. Biaya penggunaan alat re-use lebih efisien dibanding dengan penggunaan alatbaru.Kata kunci: efektifitas, efisiensi, perangkat medis re-use, baru, endoskopi
Upper Gastrointestinal Symptoms and Climate Exchange in Indonesian Hajj Pilgrims: Community Based Study Islamic Year 1427 Masdalina Pane; Chairul R Nasution; Murdani Abdullah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 8 ISSUE 2 August 2007
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/82200744-47

Abstract

Background: Upper gastrointestinal symptoms rank among the three most common diseases for Indonesian hajj pilgrims in last 4 years. The prevalence was 22-34% per hajj season. Most of the cases were dyspepsia syndrome and Gastro Esophageal Reflux Disease (GERD). The internal risk factor of Upper gastrointestinal symptoms is largely known, but not for external factor such as environment and climate. Aim: To examine the association between climate exchange and upper gastrointestinal symptoms Methods: Dynamic population of 204,941 Indonesian Hajj Pilgrims in Islamic year 1427 were included for this study. Multiphase screening in Indonesia found the prevalence of upper gastrointestinal symptoms was 3.32%. Prospective follow up for upper gastrointestinal symptom-based on community health services (flight group/kloter and maktab policlinic/polimaktab) and hospital base (Sub Balai Pengobatan Haji Indonesia, Balai Pengobatan Haji Indonesia [BPHI] and Saudi Arabia hospital) was conducted in Saudi Arabia. Results: The incidence rate of the upper gastrointestinal symptoms was 2.4 per mile (95% CI = 1.8 -3.1). There was no significant difference among male and female p = 0.279 (95% CI = 0.18- 5.3) and there was significant difference among work area (Daker) p = 0.001 (95% CI = 50.4-182.5). There was no significant correlation between upper gastrointestinal symptoms and temperature or humidity in 3 work area (p = 0.155) Mecca, Medina and Jeddah. Conclusion: There was no significant correlation between climate exchanges to the upper gastrointestinal symptoms. Keywords: upper gastrointestinal symptoms, Indonesian Hajj Pilgrims, dyspepsia, GERD
Barrett’s Esofagus Syifa Mustika; Bayu Eka Nugraha
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 20, No 2 (2019): VOLUME 20, NUMBER 2, August 2019
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (824.84 KB) | DOI: 10.24871/202201996-103

Abstract

Gastroesophageal reflux disease (GERD) is a condition commonly managed in the primary care setting. Patients with GERD may develop reflux esophagitis as the esophagus repeatedly is exposed to acidic gastric contents. Over time, untreated reflux esophagitis may lead to chronic complications such as esophageal stricture or the development of Barrett’s esophagus (BE). BE may progress to oesophageal adenocarcinoma. There is currently a rising incidence of BE. The pathogenesis of BE is not well-understood although genetic and environmental factors play significant roles. BE is characterized by the replacement of distal esophageal stratified squamous epithelium by columnar epithelium. It is rare in children and the risk factors may include mental retardation, cerebral palsy, esophageal atresia, etc. As patients with BE can be entirely asymptomatic, it is difficult to screen this population group. BE is present in 10%–20% of patients with GERD and has also been detected in patients who deny classic GERD symptoms and are undergoing endoscopy for other indications.
Effect of Intravenous Polyunsaturated Fatty Acids Administration on Gastric Mucosal Integrity in Pig-tailed Macaques with Obstructive Jaundice Dadang Makmun; Dondin Sajuthi; Daldiyono Daldiyono; Adi Winarto; Erni Sulistiawati
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 12, NUMBER 1, April 2011
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (908.415 KB) | DOI: 10.24871/12120118-14

Abstract

Background: Acute gastric mucosal injury commonly occurs in patients with obstructive jaundice. We studied the effect of intravenous polyunsaturated fatty acids (PUFA) administration on gastric mucosal integrity in pig-tailed macaques (Macaca nemestrina) with obstructive jaundice by ligating common bile duct (CBD). Method: The study was conducted between February 2009 and May 2010 at the Primate Research Center, Bogor Agricultural Institute. Eight selected male pig-tailed macaques with 6.625 ± 0.83 kg of body weight were used and divided into two groups. In both groups, laboratory examination, including liver function tests and upper gastrointestinal endoscopy were performed before CBD ligation and every two weeks after ligation. In the first group, intravenous PUFA with the dose of 2 g/day was administered every day since four weeks post-ligation up to four weeks later, and in the second group, intravenous PUFA was administered since before ligation up to eight weeks later. Results: In both groups, increased total bilirubin, direct bilirubin, indirect bilirubin, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and gamma glutamyl transpeptidase were obviously found, meanwhile decreased albumin level was detected and the cholinesterase level of both groups remained unchanged. Ulcer formation occurred among the first group during 4 weeks after CBD ligation, and these ulcers showed obvious healing within four weeks after intravenous PUFA administration. In the second group, there was no significant ulcer formation within eight weeks after CBD ligation. Conclusion: The potential appearance of acute gastric mucosal injury which reflected by ulcer formation in pig-tailed macaques with obstructive jaundice was significantly decreased by intravenous PUFA administration. We also have successfully developed animal model of obstructive jaundice by CBD ligation, based on the result of liver function tests. Keywords: acute gastric mucosal injury, intravenous PUFA administration, obstructive jaundice, pig- tailed macaques
Diarrhea as a Prognostic Factor for Severe COVID-19 Dinda Nisrina; Hasan Maulahela
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 23, No 2 (2022): VOLUME 23, NUMBER 2, August 2022
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (502.539 KB) | DOI: 10.24871/2322022266-271

Abstract

In March of 2020, the WHO has declared the state pandemic of COVID-19 that started in the city of Wuhan, China. The widespread of cases resulted in 2,877,476 cases and 73,582 death reported in Indonesia. It is commonly known that the respiratory system was the main problem in COVID-19, but it is recently reported that gastrointestinal involevment has a higher likelihood to develop into severe cases. Moreover, it is found that diarrhea is the most highly prevalent of the gastrointestinal signs and symptoms in COVID-19 patients. The aim of this evidence-based case report is to understand the association between diarrhea and severe cases of COVID-19. A search on Pubmed, Scopus and Cochrane result in five articles to be appraised using Centre for Evidence-Based Medicine (CEBM) critical appraisal tool. The most recent systematic review by Ghimere S et al (2020), found COVID-19 patients with diarrhea has higher likelihood of developin ginto a severe case (OR = 1.63, 95% CI: 1.11 – 2.38). While the cohort studies showed several prognostic factors that may potentially effect the outcome of severe COVID-19 cases. It is concluded that severe COVID-19 cases were more likely to be found in patients presenting with diarrhea. Thus, Confirmed COVID-19 patients with diarrhea should be carefully evaluated to anticipate worsening of symptoms.
Impact of Low Fiber Diet on Gastrointestinal Disorders Ari Fahrial Syam; Daldiyono Daldiyono
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 4, NUMBER 1, April 2003
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/41200311-13

Abstract

Fiber is not digested or absorbed in the small intestine. The main site of action of fiber is in the colon. In the colon, fiber will increase stool output and frequency, increase stool water, dilute the colonic content, reduce the toxins, bile acid, increase colonic fermentation and also stimulate probiotic growth. Some meta-analysis of observational epidemiologic and case control studies have found a protective effect of dietary fiber against colon cancer that increase with intake. Therefore, the high fiber diet is healthy recommendation to prevent various gastrointestinal disorders.   Keywords: dietary fiber - colon cancer - constipation
The Difference of Gastric pH in Dyspepsia Patients With or Without Type 2 Diabetes Mellitus Ilum Anam; Ari Fahrial Syam; Dante Saksono Harbuwono
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 16, No 1 (2015): VOLUME 16, NUMBER 1, April 2015
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (167.929 KB) | DOI: 10.24871/16120157-12

Abstract

Background: Dyspepsia syndrome often experienced by patients with diabetes mellitus (DM). Gastric acid is one of the aggressive factors of syndrome dyspepsia and peptic ulcers. This study aims to find the difference of gastric pH in dyspepsia patients with DM and without DM, and also to determine whether there is any correlation between gastric pH with proteinuria and hemoglobin A1c (HbA1c).Method: Two groups of patients consisted of 30 patients with DM and 30 patients without DM. Basal gastric pH of each group counted. Basal gastric pH was measured by inserting electrode catheter into the stomach for 30 minutes and then recorded on PH Metri brand Digitrapper pH-Z. Complication of DM was measured by microalbuminuria, while blood sugar control was measured by HbA1c. Chi-square test was done to look for difference of gastric pH between the diabetic patients group and non-diabetic patients group, by first determining the point of intersection with receiver operating characteristic (ROC) analysis. Correlation test between basal gastric pH with microalbuminuria and HbA1c were done.Results: Basal gastric pH in dyspepsia patients with DM vs. dyspepsia patients without DM was 2.30 ± 0.83 vs. 2.19 ± 0.52. With the Chi-square test, there is a significant difference between the diabetic patients group and non-diabetic patients group. With the correlation test between gastric pH and microalbuminuria was found r = 0.47 and p 0.05, whereas the correlation test between gastric pH and HbA1c was found r = 0.59 and p 0.05.Conclusion: There is a significant difference between basal gastric pH in diabetic dyspepsia patients and non-diabetic dyspepsia patients. There is a correlation between basal gastric pH and microalbuminuria, whereas there is no correlation between basal gastric pH and HbA1c.

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