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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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The Impact of it Strategic Planning on Human Resource Management Information System Hakimeh Shahriyari
Journal of Global Pharma Technology Volume 08 Issue 02
Publisher : Journal of Global Pharma Technology

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Abstract

The objective of this study is to investigate the impact of IT strategic planning on Human Resource Management Information System. This is a descriptive-analytical research and in terms of objective, this is an applied study. The statistical population of this study consists of all managers, supervisors and experts in Zabol University of Medical Sciences. Data collection tool is questionnaire with content validity and the overall reliability of 0.81 that is calculated using Cronbach’s alpha. The results of this study showed that there is a positive and significant relationship between IT strategy and factors of “coordination of tasks in the Human Resource Information System”, “Interaction between beneficiaries of information”, “Maturity of information systems” and “Focus on organizational structure” with respectively Pearson’s correlation coefficients of 0.43, 0.45, 0.33, and 0.45.
Production of Dried Roasted Watermelon (Citrullus Lanatus) Seed Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 11 Issue 01.
Publisher : Journal of Global Pharma Technology

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Abstract

Watermelon seeds are a source of protein, B vitamins, and minerals. The watermelon seeds are often discarded while the fruit is eaten. Watermelon seeds are considered as a good source of food for human nutrition and health. Drying and roasting are the most important processes giving necessary alterations to the product.  Roasting can enhance flavour through caramelization on the surface of the food. There was no any research mentioned to varify the change of antioxidant (tocopherol) during infrared drying as well as storage. So the objective of the present study was to identify the effect of temperature in infrared drying, roasting condition, packaging and storage to tocopherol, total phenolic and antioxidant activity in the dried roasted watermelon (Citrullus lanatus) seed. Results demonstrated that drying temperature (45 oC), roasting (165 oC in 3 min), vaccum packing in polyethylene (PA) bag and keeping in 4 oC were recommended to maintain the tocopherol, total phenolic and antioxidant activity in the final products for 16 weeks. The effect of drying, roasting temperature and time were clearly demonstrated to produced dried roasted watermelon seed.Keywords: Watermelon seed, Drying, Roasting, Antioxidant, tocopherol, Phenolics, vaccum.
Clinical Study of Vitamin D3 Deficiency and some Trace Elements in Autism Husam M. Kredy
Journal of Global Pharma Technology Volume 11 Issue 07
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Abstract

Autism is a disorder of nerve growth characterized by weak social interaction and verbal and nonverbal communication, as well as restricted behavior and stereotypes. The subjects of the study were 90 autistic children with varying degrees of severity (mild, moderate and severe) who were diagnosed with DSM-IV, thirty children in each group and 30 healthy children (age and sex were identical). The boys and girl ratio involved in this study was 4:1, and they were 4-12 years of age. The study showed a significant elevation in the levels of Cu and Pb in the blood sample of autistic children when compared to a healthy control group. The elevation was much pronounced in severe group subjects when compared among autistic groups mild and moderate. The levels of Zn and Vitamin D3 were significantly decreased in autistic children when compared to control. The Zn and Vitamin D3 showed significant variation in blood of severe group children when compared to control group and other study groups. The correlation between Zn and Vitamin D3 in these patient groups were positive. Whereas the correlation between Zn and each of (Cu and Pb) in these patient groups were negative.Keywords: Autism, Children, Blood, Trace Elements, Vitamin D3.
Evaluation of Lipid Profile and Cytogenetic Disturbance in Hypertensive Patients Tayseer Shamran Al-Deresawi
Journal of Global Pharma Technology Volume 10 Issue 07: (2018) July 2018
Publisher : Journal of Global Pharma Technology

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Abstract

In the purpose of studying the differences between normal and hypertensive people, this study was focused on estimating these differences using lipid profile and cytogenetic effects. To initiate this process, sampling of blood from 33 patients and 25 healthy individuals of 3 different age categories was performed in Al-Zahra Teaching Hospital and Al-Karama Hospital in Wasit province, Iraq. These blood samples were subjected to measuring cholesterol, triglycerides (TG), HDL, and LDL. Moreover, blood lymphocytes were employed to visualizing certain cytogenetic disturbance indicators such as mitotic index (MI), nuclear division index (NDI), and Micronucleus (MN). When looked at patient group, the results identified significant (p˂0.05) differences between groups revealing increases in all the tested lipids except decreases in HDL. In case of cytogenetic effects, significant increases (p˂0.05) were seen in the MI, NDI, and MN in all patients at all ages. Here, the results indicate important role of blood hypertension in having specific lipid profile and most importantly the changes in the activity of the cells to increase unwanted proliferation.Keywords: Blood Hypertension, Lipid Profile, Cytogenetic.
Promoting Awareness of Mental Retardation to Prevent Epidemiological Binge Mainul Haque
Journal of Global Pharma Technology Volume 09 Issue 11
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Abstract

Promoting Awareness of Mental Retardation to Prevent EpidemiologicalBinge
Fermented Juice Production from Persimmon (Diospyros kaki) Fruit Minh Phuoc Nguyen
Journal of Global Pharma Technology Volume 12 Issue 01
Publisher : Journal of Global Pharma Technology

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Abstract

Persimmon (Diospyros kaki) reveals beneficial health effects owing to nutritional components and antioxidant capacity. It is a good source of fiber, phenolics, minerals, vitamins and other bioactive compounds. However it’s sensitive to deterioration in a short harvest season. In this study, fermentation of persimmon juice with probiotic bacteria Lactobacillus acidophilus as well as effectiveness of several technical variables in pretreatment and fermentation were investigated.  Our results revealed that thermal treatment 650C in 4 minutes and then cooling at 40C in 20 minutes were appropriate for tannin reduction to mild astringent taste. The initial inoculations (108 cfu/ml) of Lactobacillus acidophilus, 8% sugar, pH 4.4, temperature 37oC were suitable for persimmon extract fermentation within 24 hours. Persimmon juice fermented probiotic Lactobacillus acidophilus was highly value for human health.Keywords: Persimmon, Lactobacillus acidophilus, Fermentation, Probiotic, Tannin, Thermal.
Synthesis, Characterization and Study Biological Activity of Some New Compounds Derived From Phthalic Anhydride Nebras M. Jamel
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

In this research ,  phthallic anhydride ring  is opened with 4-methyl aniline and acetone as a solvent  to results the compound [I] that reacted with dimethyl sulphate and anhydrous sodium carbonate formation to phathalate ester [II], while the acid hydrazide compound  [III], was obtained  from mixed the compound [II]with  hydrazine hydrate, Synthesis four type of shiff bases[IV]a-d   was synthesized  from the reaction  of acid hydrazide [III] with aromatic aldehyde or ketone , when reacted Shiff bases with   phthalic anhydride or naphthalicanhydride,I get eight derivatives  of oxazepine [V]a-d , [VI]a-d. The bacterial activity of the new compounds studied by four species of bacteria: Esherichia Coli, Enterobactecloacae (Gram negative) and staphylococcusaureus, Bacillus subtilis (Gram positive). These compounds were identified by FTIR,1HNMR and Mass (of some of them).Keywords: Schiff bass, 1, 3-oxazepine and antibacterial activity.
Synthesis of New Reagents and Studying of (Spectral, Chromatography, Thermal, Solubility) Behavior Nagham Mahmood Aljamali
Journal of Global Pharma Technology Volume 09 Issue 11
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Abstract

New reagents were prepared from cephalexine drug as macro reagents via several steps like ( esterification , substitution , condensation, insertion ) reactions to produce new analytical reagents . The first reagent involved two imine group , while the second reagent included two amide groups ,and third reagent involved two amide as a cycle by insertion reaction. Our reagents investigated by chemical techniques like ( FT.IR , H.NMR , Mass )- Spectra and studied through ( chromatographic curves , thermo curves ) ., which indicated our results and gave evidences for formatted reagents. Keywords: Reagent, Ester, Amide, Insertion, Cephalexine.
An Analysis of the Quality of Patient Development Integrated Records as System Information Among Healthcare Professionals Muhammad Hadi
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
Publisher : Journal of Global Pharma Technology

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Abstract

Patient Development Integrated Records (CPPT) is the documentation for health personnel in conducting the assessment of hospitalized patients according to the Hospital Accreditation Committee Standard (KARS). The CPPT is a tool for all health professions to convert the data and treatment plan for the patient. This would lead to a collaboration and communication between healthcare professionals at the hospital. This study aims to analyze CPPT as the information system between healthcare professionals at the hospital. This design study used a mixed-method with quantitative research as a source of primary data and qualitative research as secondary data. This research used cross-sectional approach as the quantitative tool, involving 76 health workers, most of whom were nurses. The sample was done by systematic sampling. Data collecting was done using questionnaires chi-square bivariate analysis and multivariate logistic regression. Qualitative research was done through interviews, focus group discussions and documentation with the status of 140 documents. The results of this quantitative study showed that the quality of study documentation in hospitals is still 80,3%, good category, and based on documentation study shows 52.9%. Meanwhile, as an information system between professionals was influenced by education, length of work, understanding of the Standard Operating Procedure (SOP) and concern of health professionals who write Patient Development Integrated Records, with the most dominant factor is the knowledge of SOP with (p=0.003). These factors should be a concern for the hospital management as the evaluation in order to improve care to patients, patient safety and protect health care workers from lawsuits.Keywords: Influential factor, Inter-professional information system, Patient development integrated records.
Application of Electronic Medical Record at Intensive Care Unit in Maternity and Children Hospital Moustafa Ali Ghazi Al-Shammari
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

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Abstract

Background: Electronic medical record implementation within the PICU to measure the system effectiveness with analysis the user's attitude toward the system use based on TAM3. Methods: A controlled before and after study, started from 29th Sep 2016 to 11th May 2017, were conducted in the PICU of Children Hospital. A convenience (probability) sample of pediatric patients was selected before and after EMR use. And a purposive (non-probability) sample of PICU staff was selected after 3 months of EMR application. The data were gathered from sheets in the before and after period by stopwatch and an excel spreadsheet tool. In addition to, the electronic questionnaire developed based on TAM3 by using (google forms) used to collect data from the respondent survey, for the period from (14th March - 30th April 2017). Data were analyzed using SPSS®, through applying descriptive and inferential analysis as; frequency, percentage, mean, Cronbach's alpha test, and paired-samples T test. Results: The results were the documentation time was faster using electronic recording, (10.25 min 0.38sc vs 23.9 min 0.43 sc; p < 0.001). And documentation completeness was enhanced significantly after application. All PICU users enrolling in the afterward time accomplished analyses were having highly scored of attitude toward EMR system use.  Conclusion: The EMR system implemented in the PICU overall succeed, electronic charting was faster, as well as the documentation completion recording was significantly improved. The healthcare members were having a positive attitude toward adoption of the system.Keywords: Documentation completeness, EMR, Implementation process, PICU, Technology acceptance model 3, Time.

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