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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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Educational Obstacles Facing Primary School Teachers in Iraq from their Point of View Diaa Saleh Mahdi Al-Attar
Journal of Global Pharma Technology Volume 10 Issue 06: (2018) June 2018
Publisher : Journal of Global Pharma Technology

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Abstract

The aim of this study is to identify the real obstacles related to primary school teachers in Iraq, which impede the development of the educational process, especially with regard to the student, curriculum, school administration and school buildings. To achieve this, a questionnaire was designed as a main tool in this study, the study sample consisted of (120) teachers and teachers in the schools of Karbala governorate. To collect the data from the members of this sample, a questionnaire was used consisting of five main fields. The validity and consistency of this questionnaire were verified. The results of the study showed that the teachers' awareness of the importance of the teacher and overcoming the obstacles to the performance of the tasks of his profession. The results of the study also revealed the impact of these axes on the role of the teacher is uneven, and the study presented a number of suggestions and recommendations.Keywords: Educational obstacles, Facing primary and school teachers.
Genotyping of Interleukin-1B SNPs in Correlation with Coronary Heart Disease associated Gingivitis Fatima Malik Abood
Journal of Global Pharma Technology Volume 9 Issue 10
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Abstract

Objective: Designed to detect most important bacteria implicated gingivitis associated coronary heart disease and investigate interleukin-1 beta gene polymorphism (SNPs) and their possible role with CHD cases with and without chronic gingivitis at positions IL-1????-13 and IL-1????-511.Background:  Coronary heart disease is impaired blood flow in the arteries that supply blood to the heart. Methods: Study subjects consisted of 40 (22 males and 18 females with 45-76 year old, mean 63±6.18) and 30 control (18 males and 12 females) who were gingivitis free, from each subject 2 specimens (swab for bacterial isolation and 5mm of venous blood were taken in EDTA tubes for DNA extraction.IL-1B-31 and IL-1B-511SNPs were amplified by PCR and DNA products sequenced in Gen Bank (Gen Bank accession number NC-000009.11) and scanned for detecting IL-1B-31 and IL-1B-511SNPs. Results: bacteriological study was showed the dominant bacteria in patients were viridians streptococcus, staphylococcus aureus, black pigmented bacteria and candida. The numbers of theses bacteria in patients were higher than control. Genetic study showed three genotypes for -13IL-1B SNP among patients; CC, CT and TT were 29 (72%), 8 (20%) and 3 (7.5%) respectively, However, only two genotypes among control; CC: (27(90) and TT: (3(10), with no significance differences between patients and control (OR= 0.9 (0.87–1.07). While only two genotypes for -115IL-1B SNP among patients; CC: 31 (77.5%) and CT: 9 (22.5%). However, in both SNPs C allele frequency was (dominant) among patients and control. With significance differences p≤ 0.05) (OR=2.829, 95%CI), (OR=1.0(0.85–1.17) respectively, Conclusion: the presence of theses bacteria and SNPs at position -511and -13 of IL1B gene are associated with the severity of CHD with gingivitis and may affect the secretion of IL1B cytokine.
The Effect of Special Visual Exercises in the Development of Visual Tracking and the Accuracy of Spike in the Volleyball for Young Players Bassem Hassan Ghazi
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

The Aims of Research toPreparation of visual exercises, especially in the development of visual tracking and the accuracy of the spike of the volleyball young players.To identify the impact of exercise visual especially in the development of visual tracking and the accuracy of the spike of the volleyball of young players.The Hypothesis wasSpecial visual exercises have a positive effect on the development of visual tracking and the accuracy of the volleyball spiking of young players.As for the research method, the researchers chose the experimental approach as the appropriate method to solve the research problem by designing the experimental and control groups with the tribal and remote tests as it fits the nature of the research problem.The sample of the research was chosen from the research community represented by the young players in the volleyball of the middle region (3 clubs) in Iraq at the age of 17-19 years and the number of (36) player has been selected two clubs, including the number of (20) player after the expulsion of the player prepared randomly by lot to represent the two groups Experimental and control of the sample of the search and the reality of (10) player for each group.The Researchers ConcludedAn evolution in visual tracking and accuracy of the volleyball team's spikein volleyball skill.There is a preference for the experimental group in the tests of the dimension of visual tracking and the accuracy of spiking in the volleyball.The various special exercises developed by the researchers contributed to the development of visual tracking and the accuracy of the spiking skill.The recommendations wereThe need to use special visual exercises to develop the visual tracking of players, especially young people.The need to use special visual exercises to increase the accuracy of the skill of spiking.The need to use special visual exercises to increase the excitement and excitement of young people and increase their motivation for training.Keywords: Visual exercises, Accuracy, Spike and volleyball.
Fabrication of PS/PMMA/MgO Nano Composites: Structural and Optical Properties as Coating Materials for Antibacterial Applications Ahmed A. Auda
Journal of Global Pharma Technology Volume 11 Issue 04.
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Abstract

Optical properties of P.S.P.M.M.A. polymer composite with doped MgO nanoparticles have been studied. The composite study was prepared by the solution of casting. Various concentrations were used for polymer material P.S- P.M.M.A/ (75 %-25 %). The weight ratios for Nano material (MgO) were 0 %, 2 %, 4% and 6 % of the total weight for the 1g sample. The optical spectrometers were measured at a wavelength of 220 nm-890 nm using a FTIR device optical properties of PS such  as  absorbance,  transmittance, absorption  coefficient, refractive  index,  extinction  coefficient,  real   and  imaginary  parts  of dielectric constant have been investigated. The results of the test on the refractive index, the attenuation coefficient and the insulation constant in its real and imaginary parts give good results with increasing the concentration of nanoparticles. The composite materials of polymer and nanoparticles were applied as antibacterial to Pseudomonas bacteria and they give the concentration (0.02 and 0.04 MgO) a good effectiveness to those bacteria.Keywords: Optical properties, Polystyrene, PMMA, Pseudomonas Bacteria.
Liver Regenerative and Hepatoprotective Effects OF Moringa Oleifera Extract in the Liver Fibrosis Animal Model Supriono Supriono
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
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Abstract

Objective: This study was conducted to know the liver regenerative and hepatoprotective effects of Moringa oleifera (MO) in the animal models of liver fibrosis. Methods: The study was a randomized post-test only controlled group design. Male Rattus novergicus of liver fibrosis caused by induction of CCl4 was treated with extract of (MO). Histological of the liver tissue with hematoxylin and eosin (H&E) staining were investigated by a light microscope. We calculate the number of hepatocytes expressing MDA and cytokeratin-7 (CK-7) in liver tissue using the immunohistochemical analysis. Results: Induction of CCL4 for 14 weeks results in liver fibrosis (METAVIR score F-3) and improves by the administration of MO. The number of hepatocytes expressing MDA in liver fibrosis models sevenfold higher than normal models and significantly lower after treated with MO. ALT and AST in the treated models significantly lower than in the liver fibrosis models. On the other hand, the number of hepatocytes expressing CK-7 in both normal and liver fibrosis models was lower. The CK-7 significantly higher after the administration of MO. Many ductular reactions develop in the treated animal models. Conclusions: in our knowledge, this is the first study reported a liver regenerative effect of MO in the liver fibrosis, beyond its hepatoprotective effect. The mechanism of liver regenerative probably through a hepatic progenitor cell proliferation. Keywords: Moringa oleifera, liver fibrosis, liver regenerative, CK7, MDA.
Synthesis and Characterization of Some New 1,3-Oxazepine and 1,3-Diazepine Derivatives Combined with Azetidine-2-one Ruaa Wisam Adam
Journal of Global Pharma Technology .
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Abstract

This work involved prepared of some new series of chemical compounds of 1, 3-oxazepineand 1, 3-Diazepine derivatives. First step reaction of sulfadiazine with 4-amino acetophenone product of Schiff base (A) 4-((1-(4-aminophenyl) ethylidene) amino)-N-(pyrimidin-2-yl)benzenesulfonamide. Then, Schiff base [A] enter reactions with chloro acetyl chloride to product four-membrane ring  (B) 4-(2-(4-aminophenyl)-2-methyl-3-oxoazetidin-1-yl)-N-(pyrimidin-2-yl)benzene sulfonamide (B) were condensed with different aromatic aldehydes such as (p-hydroxybenzeldehyde, N,N-dimethylaminobenzeldehyde] in ethanol absolute   to give new Schiff  bases derivatives [B1-B2] respectively, Then the  resulting  imines  derivatives [B1-B2] were reacted  with  malic  anhydride  in toluene  to give new 1,3-oxazepine-4,7-dione ring derivatives [B1a-B2a] ,reaction 1,3-oxazepine[B2a] with Naphthyl amine to give 1,3-diazepine-4,7-dione ring derivatives[C].All compounds were characterized by M.P and FT-IR spectroscopy, some of them were characterized by 1H-NMR and C13NMR spectroscopy analysis.Keywords: Sulfadiazine, 4-aminoacetophenone, Azetidine-2-one, 1, 3-Oxazepine, 1, 3-Diazepine.
Effects of Components of Servant Leadership on Social Responsibility in the Agricultural Bank of Sistan Mohammad Mostafa Dahmardeh
Journal of Global Pharma Technology Volume 08 Issue 06
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Abstract

Theory of servant leader is among theories that is developing and has influenced on form and style of leadership in present century. Greenleaf believes that servant leadership is based on philosophy of being servant first. Servant leaders are those mainly focus on serving other people’s highest priority needs and on the growth and well-being of people and the communities to which they belong. So the aim of this research, is reviewing Effects of components of servant leadership on social responsibility of employees of Agricultural Bank of Sistan. Methodology of present research is applicable regarding its aim, descriptive regarding its nature and qualitative in terms of execution method. In this research in order to gather theoretical principles, library study is used.  In order to gather statistical information for research assumption, field research and search in statistical society are used. To gather information, first servant leadership and social responsibility questionnaire is prepared by interviewing experts, elites and professors, then distributed among statistical population and analyzed by SPSS software. Statistical population of this research includes 96 people of all employees of Agricultural Bank of Sistan. To determine sample population, 96 people were selected.  Sampling method is simple random. To review and analyze data, descriptive and inferential statistics were used. At inferential level, linear regression test and step by step were used to show effects servant leadership and its components on social responsibility of employees. Results indicate that servant leadership and its components have meaningful effects on social responsibility of employees. Keywords: Leadership, Servant leadership, Social responsibility, Agricultural Bank.
Study and Analysis of Raw Water and Drinking Water in Garma District, Anbar Province, Iraq Bashar Abdulazeez Mahmood
Journal of Global Pharma Technology .
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Abstract

The study included physical, chemical and biological laboratory measurements of raw water and potable water in Garma district in Anbar province in several areas (Central Garma, New Garma, Sabihat, Sabihat 1, Sabihat 2, Al-Sager, Al-Habib, AlBukhlifa, Al Busheihan, Abautai, Karagul, Dwaya, Buakakul). A comparison was made between the values of the laboratory-measured variables and their measured values in the Directorate of the Central Garma Water Project as well as their comparison with the Iraqi and international standards for drinking water. The modeling process began in September 2017 until March 2018. The study includes physical measurements (temperature, electrical conductivity, turbidity, suspended solids and dissolved solids) and chemical measurements of (pH and positive ions calcium, magnesium, sodium, potassium and Negative ions sulphates, chlorides, and total hardened bases) and biological measurements (M\Plate count1). The study showed variation in values from the Iraqi and international standard limits where there was an increase in the values of electrical conductivity and concentration of magnesium and sulphate. The rest of the values did not exceed the standard values. Linear and back linking and correlations between chemical and physical measurements of different water models were also found for all study areas using SPSS.
Synthesis, Characterization, DFT Calculation, Photochromic, Antimicrobial and Antifungal Properties of Co(II), Ni(II), Zn(II), Ag(I) Complexes with Azo Dye of 2-Aminopyrimidine Yareeb Jwad Sahar
Journal of Global Pharma Technology Volume 11 Issue 07
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Abstract

A New azo dye 3-(2-pyrimidinylazo)-4-dimethylbenzaldehyde (PADB) consisting 2-aminopyrimidine was synthesized by coupling reaction of diazonium salt and 4-dimethylaminobenzaldehyde. The PADB was further utilized to synthesis of its complexes with Ni (II), Co (II), Zn (II) and Ag (I). All the synthesized complexes were characterized by different techniques (infrared, UV-VIS and mass spectroscopies and elemental analysis). The complexes of Co (II) and Ni (II) were found to be octahedral and nonelectrolytic with general formulas [M (PADB)2 Cl2]. The complexes of Zn (II) and Ag (I) were tetrahedral and electrolytic with general formulas [Zn (PADB) Cl2] and [Ag (PADB) (H2O)] NO3 which iselectrolytic. The PADB and its complexes exhibited potent antimicrobial activities against two types of bacterial strains, Staph-aureus (positive gram) and E-coli (negative gram) and two types of fungies: Aspergillus niger and Pinicillium-Sp. The PADB dye exhibited good phtochromic and solvachromic properties.Keywords: Pyrimidine, Photoisomerization, Pyrimidinylazo, Biological activity, Inorganic chemistry.
Prevention of Oral Health in Persons with Tobacco Smoking of Steam Cocktails Elena Emelina
Journal of Global Pharma Technology Volume 12 Issue 11 (2020) Nov. 2020
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Abstract

Recently, tobacco smoking has an epidemiological character. The largest number of smokers, according to many studies, was found between the ages of 30 and 35. Studies conducted by the World Health Organization (WHO) indicated that if a young man smoked at least two cigarettes, 70 out of 100 would continue to smoke for life. Due to the increasing prevalence of tobacco smoking, WHO began to consider smoking not only as a bad habit, but also included tobacco dependence in the International Statistical Classification of Diseases and Health Problems (10th revision); Class V: Mental and behavioural disorders; group: Mental and substance use behavioural disorders; heading: Mental and behavioural disorders caused by tobacco use (code F 17). Keywords: Oral hygiene, Tobacco smoking, Hookah smoking, Health, Safety, Smoker.

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