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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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Furnace Redesign to Reduce Levels of Dust in the Air, Fatigue, Workload, and Increasing Blacksmith Productivity in Batu Sangiang Village, Tabanan, Bali-Indonesia Ida Ayu Made Sri Arjani
Journal of Global Pharma Technology Volume 11 Issue 08 (2019) Aug. 2019
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Abstract

Introduction: Exposed to a hot environment for work is a situation that can potentially pose a danger to the safety and health of workers. Besides resulting in pain and injury, it can also cause occupational diseases. Blacksmithing was carried out with furnace and open flame, where the iron that will be heated with a sharp object repeatedly were sharpened again. The working process is quite heavy with exposure to heat radiation from the furnace and dust increasing fatigue and workload of a blacksmith. Therefore, to avoid the occurrence of health problems caused by exposure to high heat furnaces, a need for an ergonomic and good chimney that can provide comfort for its workforce. The purpose of this research is to reduce levels of dust in the air, fatigue, workload, and increasing blacksmith productivity in Batu Sangiang Village, Tabanan with furnace redesign. Methods this is an experimental research study. This research was conducted in the Batu Sangiang Village, Tabanan with a sample of 15 workers. Data collected include: levels of dust in the air, fatigue, workload, and work productivity. Before setting up a different test, the data normality was tested using Shapiro-Wilk test with a confidence level α = 0.05. In normal distributed data, Paired Sample t-test with α = 0.05 was used and abnormal distributed data were analysed using the Wilcoxon different test, α = 0.05, Results After working furnace was redesigned, decreased levels of dust in the air 89.20%, 24.03% reduction in fatigue, reduced workload of 14.48% and 83.26% increase in productivity. Results analysis using Paired Sample t-test, the amount of dust in the air, fatigue and workload in Period I and Period II, there is a significant difference (p <0.05), as well as analysis data using Wilcoxon test, labor productivity in Period I and period II, there is a significant difference (p <0.05). Conclusion: From this study we can conclude, after the furnace redesign was done, there was a significant decrease in the levels of dust in the air, fatigue and workload, and there was a significant increase in labour productivity. Suggested artisan blacksmith always applies and pay attention to the principle of ergonomics for improvements such as the redesign of the furnace shown to reduce levels of dust in the air, fatigue, and the workload and increase productivity.Keywords: Furnaces redesign, Levels of dust in the air, Fatigue, Workload and work productivity.
The Addition of Caffeine in EBSS Media by Sperm Swim-up Washing Method Increased the Human Sperm Motility and Acrosomal Reaction Bagus Komang Satriyasa; J. Alex Pangkahila
Journal of Global Pharma Technology Volume 10 Issue 08: (2018) August 2018
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Abstract

Background: Caffeine, a methylxanthine derivate, had a role as a phosphodiesterase inhibitor, thereby inhibiting the break down of cAMP and increasing its concentration inside the cell. Aim: This study aimed to assess the effect of caffeine in EBSS and evaluated the increase in motility and the acrosomal reaction of spermatozoa using the swim-up method. Method: This was an experimental study using a pre-post test control group design. This study was carried out at the Sexology and Andrology Clinic, Sanglah Hospital in Denpasar Bali. The samples were sperm specimens of eighteen infertile male or volunteers aged 20-40 years. They were divided into two groups: treatment group (caffeine + EBSS) and control group (EBSS). The data were analyzed statistically by normality test (Kolmogorov – Smirnov Goodness of Fit Test), homogeneity test and paired student’s t test. Result: The caffeine addition in EBSS medium increased the sperm motility significantly from 71.94% to 80.28% (p<0.05) and the acrosomal reaction from 83.33% to 88.89% (p<0.05). Conclusion: The addition of caffeine in EBSS medium increased the motility and the acrosomal reaction of the human sperm.Keywords: Caffeine, EBSS, Sperm motility, Acrosomal reaction, Spermatozoa.
Removal of Malachite Green from Aqueous Solution by Iraqi Porcelanite Rocks Muneer. A . AL-Da&#039;amy
Journal of Global Pharma Technology Volume 9 Issue 10
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Abstract

Removal of Malachite greendye has been carried out by using Iraqi Porcelanite rocks as an adsorbent. A series of experiments were undertaken in a batch adsorption technique to access the effect of the process variable i.e. namely initial dye concentration, contact time, adsorbent dose, initial pH, and temperature. Maximum adsorption of malachite green was achieved at the suggested optimum conditions: initial dye concentration (6mg.L-1), weight of adsorbent (0.05 g), pH solution (8.5) and contact time (30 min).Equilibrium data were well represented by the Freundlich model. Thermodynamic parameters were estimated. The negative values of the Gibbs energy indicated the spontaneous nature of the adsorption .The entropy was positive and the positive value of the enthalpy showed that the process is endothermic. The removal of Malachite green dye using Iraqi porcelanite rocks has been studied at different temperatures (298.15, 308.15, 318.15, and 328.15)K to determine the adsorption isotherms .The shapes of the isotherms obtained from the experimental data were found to be comparable in all cases to the (S- curve) type according to Giles classification.Keywords: Adsorption, Porcelanite rocks, Malachite green, Isotherms, Langmuir, Freundlich.
Assessment of Serum IL-2 and Immunohistochemistry Detection of IL-2 in Induced Hypothyroidism of Male Rats Abbas Abed Sharhan
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

This study was conducted to demonstrate the role of methanolic extract from Ficuscarica leaves in the treatment of   hypothyroidism disease which induced in male rats by carbimazole drug. Forty male rats were divided into five groups, eight for each. group I selected as a negative control  which primed orally with normal saline alone, group II served as a positive control and treated by carbimazole anti-thyroid  drug for six weeks ,while  group  III  was treated by plant extract ( 500 mg /kg, bw) for six weeks ,whereas the  fourth group IV was treated by carbimazole drug (5 mg) for six weeks to induce hypothyroidism   and then  treated by plant extract ( 500 mg /kg , bw)  for six weeks too. Finally the fifth V group was  treated by thyroxin drug (100 mg) for six week instead of plant extract.The results showed that a non- significant difference (P< 0.05) in the level of  IL-2 of  the fourth  group when compared  with the first group  , while the results revealed a significant increase when compared with the  second  group  ,whereas a significance decrease when compared with the third and fifth groups. The immunohistochemical sections of  rats thyroid gland  in the first , second and third groups revealed that weak expression of IL-2 immunopositive cells (brown cytoplasmic deposits) in thyroid sections, while rats thyroid gland in the fourth group  and fifth groups revealed that a moderate expression of  IL-2 immunopositive cells. In conclusion it is possible to use methanolic extract of Ficuscarica leaves in the regulation of immune response in hypothyroidism disease may due to the presence of phytochemical components that enhance the cellular immune response by increase the IL-2 production.                                                                                     Keywords: Hypothyroidism, Carbimazole IL-2, Immunohistochemistry, Ficuscarica, phytochemical components.  
The Effects of Methane Storage Capacity Using Telmisartan Organotin (IV) Complex Emad Yousif
Journal of Global Pharma Technology Volume 11 Issue 04.
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Abstract

The fabrication of porous dibutylorganotin (IV) complex as methane storage was successful. Interesting physiochemical properties for diorganotin (IV) complex were observed using a combination of several techniques such as scanning electron microscopy, Brunauer–Emmett–Teller and nitrogen adsorption–desorption isotherm, Barrett–Joyner–Halenda and H-sorb 2600 analyzer. The mesoporous complex exhibit tunable porosity with Brunauer–Emmett–Teller surface area (SABET = 130.357 m2.g-1), pore volume (0.162 cm3.g–1) and narrow pore size distribution; the complex was found to has high physico-chemical stability. At 323 K and 50 bars, the complex has methane uptake (up to 1.116 cm3·g–1). The field emission scanning electron microscopy images, at different 100 and 50 µm magnification powers were confirmed, the morphological images of the polymeric film showed a rough surface.  Keywords: Gas storage; Methane capture; Diorganotin (IV) complex; Field emission scanning electronic microscope.
Epidemiological Characteristics of Acute Leukemia in Child Welfare Hospital in Baghdad Samahir A. Fadel
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Background: Acute leukemia, the most common form of cancer in children, comprises approximately 30% of all children malignancies, with acute lymphocytic leukemia (ALL) being more common than Acute Myeloid Leukemia (AML) by five times. Objectives: To determine different epidemiological variables associated with acute leukemia& to determine the patterns according to socio demographic data. Patients and Methods: A cross- sectional study and the data collection was carried out for a period of four months, from the 2nd /May/2019 to 2nd /September /2019. Result: The study shows that the majority of patients were ALL & the highest percentage of ALL patients was in the age group (5-9) years, males showed higher percentage than females in both type of leukemia, the highest percentage were from Urban.The majority of patient’s parents’ education level was primary; while the highest percentage of fathers’ occupation was Private sectors & the highest percentage of mothers’ occupation were Housewife.The highest percentage of ALL patients were 4th & more Order in family& AML were the 1st child, the highest percentage of patients with Birth space (2-4) years from there brothers.The highest percentage of patients was feed from their mothers (Breast feeding) during their first year & the highest percentage of patients was normal birth weight.Majority of patient’s Parent consanguinity were not related, while the lowest percentage of patient’s Parent consanguinity were far related.There was an important association between  patients’ blood group AB & ALL. Conclusions: The study shows that the majority of patients were ALL & the highest percentage of ALL patients was in the age group (5-9) years, males showed higher percentage than females in both type of leukemia, the highest percentage were from Urban. Recommendations: Ensure good MCH system to monitor and ensure the quality of health care practice & demonstrating cultural competency to promoting more effective child health services.Keywords: Leukemia, Blood, Cancer, Childhood, Iraq.
The Role of Government Health and Education Expenditure on Economic Growth in OPEC oil Exporting Countries Ebrahim Anvari
Journal of Global Pharma Technology Volume 09 Issue 05
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Abstract

Economic growth is one of the goals of development in economic plans of every country. Achieving self- development in OPEC member Oil - exporting countries takes precise awareness of the amount of economic variables. Among these variables, oil revenues, total government expenditure, government expenditure for education and  government expenditure for health could be mentioned.In this research using panel data studies of relationship between health expenditure and education expenditure and economic growth in OPEC oil-exporting countries for 2004 to 2014. Hence, panel data method has been applied in order to estimate  models and panel var method has been applied in order to examine the causality relationships between variables. The results shows a positive meaningful relationship between oil revenues, total government expenditure, government expenditure for education, government expenditure in health, and economic growth of OPEC oil-exporting countries in the studied period. Furthermere, the result of Granger Causality test suggest that there was one –side relationship of economic growth with government expenditure for health in OPEC member countries in the studied period.Keywords: Economic growth, Government expenditure, Oil revenue JEL: H51, H40, C13.
A Survey on Peroxide Content and Acidity level of Persian Doughnuts (Zoolbia and Bamieh) in Lorestan Province, West of Iran Abdolrahim Kazemi Vardanjani
Journal of Global Pharma Technology Volume 08 Issue 10: (2016) October 2016
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Introduction: There are different chemical food contamination that causes detrimental effects on human health. For example, presence of peroxide in fried foods causes free radical formation. Free radicals are not only responsible for food spoilage, but also cause damage to body tissues and cancer, inflammatory diseases, atherosclerosis, aging and so on. The aim of this study was to evaluate the peroxide content and acidity level in Zoolbia and Bamiehin Lorestan province, West of Iran.Materials and Methods: 120 samples of Zoolbia and Bamieh doughnuts were purchased of Lorestan province distribution centers, during March 2014 to March 2015 and handled to Laboratory for chemical analysis and determination of their peroxide value and acidity.Results: present descriptive study results showed 56.92 and 43.07 % of the samples were out of standard limit and not suitable for consumption due to high levels of peroxides and acidity, respectively. The lowest and highest peroxide value were 1.1 and 2.9 mEq/kg, respectively.  The minimum and maximum acidity of the samples were 0.7 and 2.9 wt%, respectively.Conclusion: Obtained results showed high peroxide contents in Persian doughnuts in Lorestan province than standard limit.Therefore, it seems educational programs about nutrition and using proper method for cooking and frying of foods is necessary. Continuous planning and surveillance, providing practical solutions by health authorities and regulatory organs, training of food staffs, using oils a few times and especial for food frying are recommended to reduce the peroxide content in Persian doughnuts (Zoolbia and Bamieh). Keywords: Zombie and Balmier, Acidity, Peroxide, Lorestan province, Iran
The Prevalence of Infection with Scabies, Yellow Fever and Myiasis in Some Ruminants in Thi-Qar Governorate During 2017 Sadek J.T.
Journal of Global Pharma Technology .
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Abstract

The infection of external parasites is a common disease between humans and animals. Therefore, the current study aimed to investigate the prevalence of scabies disease as a disease caused by an external parasite is the mites as well as the study of other important diseases caused by viruses and Insecta such as yellow fever and myiasis. 40825 sheep, 940 cow and 2285 buffalo were examined and the infected animals were diagnosed in the laboratories of the veterinary hospital in Thi-qar governorate for the period from January to October 2017.  The incidence of scabies in sheep, cows and buffalo were 65.03%, 53.64% and 38.03% respectively. The incidence of yellow fever in sheep, cow and buffaloes was 50.81%, 55.25% and 44.67% respectively. There were also significant differences between infection percentage according months of year. The incidence of myiasis among sheep, cow and buffaloes was 94.30%, 70.43%, and 70.95% respectively with significant differences between infection according months of year for all animals examined.Keywords: Infectious animals, External parasite, Scabies, Yellow Fever, Myiasis.
Impact of Systemic Insecticides Neonicotinoids on Environment Zaid Raad Abbas
Journal of Global Pharma Technology Volume 11 Issue 07
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Abstract

Subsequently their detection in the overdue 1980s, nicotine repellers have developed the greatest extensively utilized, category of repellers universal, through significant requests fluctuating beginning plant defense (yields, greens, berries), veterinarian, harvests, and pesticides to weakly annoyance regulator in gudgeon cultivation. Nicotine presently counting for roughly single tertiary of the universe small arthropod animal repellent merchandise the yearly universe manufacture of the model nicotine, imidacloprid, was assessed selected fulness 20,000 tones vigorous material in 2010. Around stayed numerous explanations aimed at the primary achievement of nicotine: (1) there was no recognized repeller impedance in goal pests, chiefly because of their current growth, (2) their physicochemical possessions contained wthishin several recompenses concluded prior age group of small arthropod animal repellent (i.e., organic compound, compound carbamic acid, pyrethrin, etc.), and (3) they joint an supposed compact employee, then purchaser hazard. As a result of their complete landscape, there remain engaged above via the herthisages or greeneries and move from one place to another to entirely portions about the vegetable, that, in swthisch, manufacture those efficiently poisonous to eat vegetable pests. Keywords: Nicotine, Direction, Mode of action, Cultivation. Kernel handling, Transportation small arthropod animal repellent, Substance formed.

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