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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
Ethnopharmacology of The Tengger Tribe Society: Inventory Study of The Use of Medicinal Plants Hadi Prayitno; . Ari P; Erwin Nur Rif’ah; Dewi Rokhmah
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
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Abstract

The Tenggerese community is a community that inhabits the area commonly called "Tengger village". The community trust of the Tengger Tribe towards Mount Bromo and Mount Semeru is very large, so that it has created a close relationship between the people of Tengger Tribe and nature. The ethnobotany study is expected to not only be a documentation of traditional knowledge in the use of plants for subsequent generations, but also as one of the capital in the development and preservation of biological natural resources, especially for the use of traditional medicines in the Tengger tribe. This research is qualitative research. The results of the study indicate the occurrence of the Tengger Tribe Knowledge, Beliefs and Local Wisdom Inventory in Probolinggo Regency, with the decline in Tengger tribe knowledge and belief in the nature and benefits of medicinal plants. This was caused by the success of the health program by the government so that many residents took advantage of modern medicine when they were sick, Tengger Tribe who lived in Lumajang Regency showed the use of plants in every religious or cultural ritual or treatment, based on the teachings of their ancestors which is often done in the community around the informants from generation to generation. The Tengger tribe who lives in Pasuruan Regency shows that the rituals have been carried out from generation to generation and there are no special rituals when using the medicinal plants. The perceptions, attitudes and behavior of the community regarding the Tengger tribe medicinal plants in Probolinggo Regency showed a mediocre attitude because they had rarely used it as well as other forms of behavior, namely informants had not used the medicinal plants anymore, except for a few the older ones in the remote Tengger Mountain.In Lumajang, the type of traditional medicine in the Tengger tribe is actually still perceived and responded to quite positively by informants doing treatment in the traditional way within certain limits. However, they are more open to the patterns of modern medicine, especially among the younger generation. in Pasuruan Regency, residents perceive medicinal plants as plants that can treat a disease that they know from their ancestors before. Inventory of medicinal plants in the Tengger tribe domiciled in Probolinggo Regency there are at least 3 types of plants that are still used for medicinal purposes in the face of health problems such as red ferns, fennel and saffron plants. Whereas in Lumajang Regency uses include sugar cane plants, dlingu plants and banana plants for cases of health problems. The use of medicinal plants in Pasuruan Regency includes: dringu plants, black mustard greens, fennel, besides that there are also castor plants, muscle flour, ciplukan fruit, amethyst plants and ganjan plants. Keywords: Ethnopharmacology, Tengger Tribe, Society , Inventory Study, Medicinal Plants
Conventional Culture Media for the Growth of Microbes Using of Date Palm (Phoenixdactylifera) Pollen Grains (DPPG) Zahraa Abd-Alrzaq
Journal of Global Pharma Technology Volume 10 Issue 06: (2018) June 2018
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Abstract

Background: Culture media used in the laboratory for the cultivation of microorganism supply the nutrients required for the growth and maintenance. Objectives: The study was conducted to developing alternative media namely DPPG1, DPPG2and DPPG3 by using a cheap locally available materials such as date palm pollen grains (DPPG) instead of high cost artificial media such as NA, NB,SDA and SDB For culturing some bacteria and yeast, for bacteria the test organisms used were Methicillin resistant Staphylococcus aureus (MRSA), Streptococcus fecalis, Listeria monocytogenes, Bacillus subtilis, Escherichia coli, Enterobacterae rogense, Proteus mirabilis, pseudomonas fluorescence, Acinetobacter baumanni, Klebssiella pneumonia and Salmonella sp.For yeast the test organisms used were Candida tropical is, Candida albicans, and Candida Kruzi. Materials and methods: The growth rate of microbe’s strains in liquid media was investigated by measure the optical density at 600nm but the growth on solid media was indicated by the presence of microbial colonies. The viability of the bacteria and yeast was investigated by culturing every day after the preliminary period of incubation (24 hrs.) Results: The results showed that all bacteria grew in liquid media. Listeria monocytogenes, Escherichia coli, grew equal in both DPPG1 (0.83, 0.82) and NB (0.86, 0.82). Enterobacterae rogense and Pseudomonas fluorescence grew in DPPG1 (0.88, 1.12) and DPPG2 (0.81, 0.94) higher than in NB (0.59, 1.08), Klebssiella pneumonia showed good growth in both DPPG1andNB (0.91, 0.96).Candida albicans, and Candida Kruzi showed high growth in DPPG3 (1.16, 1.10).  The most tested organisms showed good growth on the solid alternative media, and still alive in 15 selected days in liquid media and showed noticeable growth on the solid media for selected 10 daysexcept the yeast C. tropical is that stops their growth on the seventh day on SDA. Discussion: The good growth indicates that DPPG extract possess sufficient amounts of nutrients for support the growth of microorganisms. Conclusion: The DPPG extract can be use efficaciously and economically for the cultivation of the bacteria and yeasts in place of high cost artificial media which used in the laboratories.Keywords: Culture media, Date palm pollen grains, Alternative nutrient sources, NA, NB, SDA, SDB, yeast, bacteria.
The Relationship between Emotional Intelligence and Patients’ Demographic Characteristics referred to Iranshahr University of Medical Sciences hospitals in 2014 Masoomeh Shahnavazi
Journal of Global Pharma Technology .
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Abstract

Background and objective the patients under hem dialysis treatment experience so much stress associated with care plans and limitations in social communication. Because of the significant role of emotional intelligence on improving mental health and the fact that there is no precise information of hem dialysis patients’ emotional quotient, the investigation of emotional intelligence in this context as well as designing and implementation of effective training programs can be regarded as a basis for enhancing this important variable. Method this is a descriptive-correlation study conducted in 2014 of the patients under hem dialysis treatment took part in the study according to the complete enumeration method and the required criteria. The data collection instruments included individual particulars and Cyberia-Shrink Emotional Intelligence questionnaire. The data were analyzed by using descriptive and analytical statistics (mean and standard deviation), analysis of variance (ANOVA), independent T-test, and Schaffer test through SPSS 16.  Findings the mean and standard deviation of emotional intelligence total score were43.99±10.50. The results indicated that there is a statistically significant relationship between emotional intelligence and gender (p = 0.03), marital status (p = 0.02), smoking status (p = 0.001), and economic condition (p = 0.04) in different age groups (p = 0.03). There was also a statistically inverse relationship between emotional intelligence mean score and systolic and diastolic blood pressure (P = 0.001and P = 0.03, respectively). Furthermore, there was not a statistically significant relationship between emotional intelligence and the variables ‘weight, educational level, occupational status, and place of residence’.  Conclusion with regard to the relationship between some demographic characteristics and emotional intelligence, designing and implementation of effective training programs can improve this crucial element in patients with chronic kidney disease and under hem dialysis treatment.Keywords: Emotional intelligence, Chronic kidney disease, Hem dialysis, Demographic characteristics.
Long Term Survival of Pseudomonas aeruginosa in Distilled Water and in Normal Saline Mohammed F. Al- Marjani
Journal of Global Pharma Technology Volume 11 Issue 09: (2019) September 2019
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Abstract

Pseudomonas aeruginosa is an important opportunistic pathogen primarily causing nosocomial infections in immunocompromised patients and is responsible for high mortality rates in burn centers, it can be isolated from hospitals, from the water in intensive care units, as well as sinks, basins, drains, showers, toilets and bathtubs, leading to transmission of P. aeruginosa infections. To determine the physiological adaptations which allow P.aeruginosa to survive in aqueous environments, we performed this experiment by transfer the bacterial cultures from Luria broth to distilled water and normal saline and incubate for 6 months and 12 months respectively. P. aeruginosa was able to survive in distilled water for at least 180 days( 6 months) and in normal saline for more than 360 days(12 months). We also examined the ability of this cells to pyocyanin production and antibiotic resistance, and the results showed that P. aeruginosa  cells were able to produce pyocyanin and resist to  cefotaxime , augmentin , ceftazidime cefepime and sensitive to imipenem , norfloxacin and gentamicin. The results of this study revealed that  P. aeruginosa bacteria can be preserved in distilled water or normal saline for several months, and able to pyocyanin production as well as antibiotic resistance. It is important to understand how this bacteria survives in water. Understanding the mechanisms of survival in water may contribute to novel solutions for the prevention of P. aeruginosa infection and transmission.Keywords: Persistance, Preservation, Saline, Water.
The Effect of Overlapping Motor Speed Response and Agility Exercises in Developing the Speed of Departure for Futsal Players Mohsen Mohammed Hassan
Journal of Global Pharma Technology Volume 10 Issue 05: (2018) May2018
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Abstract

The problem of research is that there is a problem in the weakness of possessing the ability of speed and agility in the players of the University of Kufa football stadiums, which indicates a state of weakness in the performance of skills, especially in the formation of a tactical group in the event of a rebound and rapid, because the game needs to speed in the acquisition of the ball and move To the stadium of competitors and this causes a lack of investment of these attacks and thus wasting the opportunity to achieve a goal for the benefit of the team, the objectives of the research preparation of exercises speed response motor interaction with agility to develop the speed of departure for the players of the University of Kufa futsal and to identify the impact The research community of the Kufa University football team identified 24 players as a football player. The sample of the research was chosen in the simple random way and in the drawing style of the original search community. (83.88%).The researchers conducted the pretest after all the conditions were met on 15/11/2017 corresponding to Wednesday and included the application of the tests of the speed of the motor response and agility to the members of the research sample as explained Previously. In order to determine the level reached by the players and after the completion of the exercise speed and motor response and agility on the experimental sample, the researchers carried out the post-test of all members of the research sample in the control and experimental groups, at 9 am on Saturday 20/1/2018 showed the exercises overlapping between The motor response speed and agility used by the experimental group improved the level of motor response speed and agility at a better level than the control group, indicating the effectiveness of these exercises. The experimental group achieved progress in comparison with the control group (motor speed response and agility) by achieving the specified distance within less time. The need for the attention of the operators of education and training to identify the principles and foundations that will develop physical and motor potential to achieve the goals. The need to prepare and design the exercises in the training curricula in accordance with a system that ensures upgrading the aspects of speed and agility in general because of its great impact in building a base on which a football player in the halls of possession of various other skills.Keywords: Overlapping motor, Speed response, Agility exercises and futsal.
Study Relation of the Fibrinogen and Homocysteine with Coronary Heart Disease Nasir Kareem Dhahir
Journal of Global Pharma Technology Volume 11 Issue 03
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Abstract

Because of wide spread chronic infections, especially in patients who have  the coronary heart diseases (CHD), and by measuring the inflammatory factors as a biomarker related to this disease including, fibrinogen, homocystein, and the relation of the disease with some risk factors such as the age, blood pressure, body mass index and blood sugar. The study was carried out in the Baqubah teaching hospital in a period from (September/ 2017) to (September/ 2018) in patients who are admitted to coronary care unit (CCU), including ( 35 patients with myocardial infarction, 24 males , 11 females), and( 35 patients with angina pectoris, 19 males, 16 females). The both groups are compared with other healthy group consisting of 20 persons (12 males, 8 females). The range of age was (40-70 years).  The principles of method used is by (7 ml) of blood from each patient to estimate the level of serum fibrinogen by using coagulation homeostasis analysis device, and the homocystein is measured by using ELISA technique, and the measuring of the other biochemistry factors by using Cobas Integra 400 plus device. The results of the study showed that, there is a significant value difference  p < 0.05 of fibrinogen, homocystein, body mass index, systolic blood pressure, fasting blood sugar of patients with myocardial infarction and angina pectoris compared to control (healthy), the levels of the fibrinogen and homocystein will elevated with extreme of the age and increase body mass index (BMI), also there is a positive correlation (r=0.04) and in significant value (p=0.70) for homocystein and systolic blood pressure, and the correlation (r=0.08) in significant value (p=0.46) for homocystein and diastolic blood pressure, while the levels of the fibrinogen to systolic blood pressure is(r= - 0.19) in significant value (p=0.07)but the diastolic blood pressure (r= - 0.09) in significant value (p=0.35). Also there is less positive correlation of fibrinogen to blood sugar (r=0.039) in significant value (p=0.71) while there is a negative correlation (r= - 0.04) in significant value (p=0.72) between homocystein and blood sugar. Aim of the study: to investigate the effect of levels of the inflammatory factors involving the fibrinogen and homocystein with relation to coronary heart diseases and study the correlation with other risk factors such as age, blood pressure, body mass index and blood sugar.Keywords: Fibrinogen, Homocystein, Coronary heart diseases (CHD), Body mass index (BMI), Myocardial infarction, Angina pectoris, Blood sugar,  Cardio vascular diseases(CVD).
Synthesis, Characterization, Antibacterial and Antifungal Activity of Some Bis (1, 3, 4-oxadiazole) Polymer Nawar Jamal Abdul Rada
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Abstract

Pyridine-2, 6-dicarbohydrazide comp (2) was synthesized from ethanolic solution of diethyl pyridine-2, 6-dicarboxylate comp (1) with excess of hydrazine hydrate. Newly five polymers (P1-P5) were synthesized from reaction of pyridine-2, 6-dicarbohydrazide comp (2) with five different di carboxylic acid in the presence of poly phosphoric acid (PPA). The antibacterial activity of the synthesized polymers was screened against some gram positive and gram negative bacteria.  Antifungal activity of these polymers was evaluated in vitro against some yeast like fungi such as albicans (candida albicans). Polymers P3, P4 and P5exhibited highest antibacterial and antifungal against all microorganisms under test.Keywords: Bis 1, 3, 4-oxadiazole, Polymer, Antibacterial, Antifungal.
Evaluation of Antimicrobial Activity of the Aquatic Extract against Bacterial isolates from URTI in Babylon Province, Iraq Ayad F. Alkaim
Journal of Global Pharma Technology Volume 09 Issue 12
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Abstract

Background, The other infections of patient in the hospitals may be occur resulting   from high drug résistance bacteria and causes mortality. The study have been aimed to investigate the antibacterial activity of aqueous extract Borago officinalis L., Cydonia oblonga., Matricaria chamomilla against most prevalence pathogenic bacteria. Methods; the aqueous extract  Borago officinalis L., Cydonia oblonga., Matricaria chamomilla were used to investigate the antibacterial activity pathogenic bacteria by Agar well diffusion method. Result; the Result showed that the crude of all plants extract have potential antibacterial activity. Conclusion; Based on the results it can be concluded that plants extract can inhibit bacterial colonization and adherence to upper respiratory tract infection, and provide production against different human pathogens and this may have clinical relevance.Keyword: Borago officinalis L, Cydonia oblonga, Matricaria chamomilla, Pathogenic bacteria.
Training Complexity in Accordance with the Change in the Radius of the Jogging Curve in the Development of Some Physical Abilities and Mechanical Variables to Accomplish 200 Meter for Youth Mazin Anhair Lami
Journal of Global Pharma Technology .
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Abstract

The objective of the research was to identify the effect of the special exercises to increase the training complexity according to the change in the radius of the jogging curve in the development of some physical abilities and biomechanical indicators and the achievement of running 200 m for youth. The sample of the research was short distance sprinters for the youth group within the clubs of Wasit province for the sports season 2017-2018. (12) Runner, the researcher used the experimental method of the two equal groups. And a set of standardized tests to measure physical capacity. The biomechanical variables were measured using cameras with a speed of 240 r / s and then analysis of the films by Kenova. The exercise was implemented by three training units per week with a total of (24) units, The tests were carried out by the pretest and post conditions and procedures and method of work, the researcher used the statistical bag (SPSS) to reach the test hypothesis of the search, a set of results to compare the experimental group and control were all significant results for the benefit of the experimental group in the brother except for the variable speed, the results were not significant.Keywords: Training complexity, Jogging curve physical abilities and mechanical variables.
The Effect of the Use of Semicircular Device to Learn the Performance of the Two Stages of Planting in the Box and Raise the Jump Pole for Female Students Mohammed Naji Shaker Abugneam
Journal of Global Pharma Technology Volume 11 Issue 6.
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Abstract

The study included the design, manufacture and use of a semi-circular circular mechanical device. Mechanisms were used to learn the technical stages of performance by jumping the pole for female students. It was installed on the ground. And thus helped the students to perform easily as the effectiveness of bowel jump needs physical and motor abilities in addition to the correct technical performance as well as the general neuromuscular consensus according to the paths of movement, especially for students .The exercise was applied to the device from the group of experimentation Of term (6 weeks) by two units learning at a rate of 12 educational units then it was compared with the control group in reserving the technical performance of the digital level as statistical results showed experimental superiority over the control.Keywords: Design, Educational device, Jumping and learning.

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