cover
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
Synthesis, Characterization, Thermal Study, Biological Activity and Corrosion Inhibition of New Ligand Derived from Butanedioyl Dichloride and Some Selective Transition Metal Complexes Enass J. Waheed
Journal of Global Pharma Technology Volume 11 Issue 2: 2019
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The new ligand [N1,N4-bis((1H-benzo[d]Glyoxalin-2-yl)carbamothioyl)Butanedi amide] (NCB) derived from Butanedioyl diisothiocyanate with 2-aminobenz imidazole was used to prepare a chain of new metal complexes of Cr(III), Mn(II), Co(II), Ni(II), Cu(II), Pd(II), Ag(I), Cd(II) by general formula [M(NCB)]Xn ,Where  M= Cr(III), n=3, X=Cl; Mn(II), Co(II), Ni(II), Cu(II), Pd(II), Cd(II) ,n=2 , X=Cl; Ag(I), n=1, X=NO3. Characterized compounds on the basis of 1H, 13CNMR (for (NCB), FT-IR and U.V spectrum, melting point, molar conduct, %C, %H, %N and %S, the percentage of the metal in complexes %M, Magnetic susceptibility, thermal studies (TGA),while its corrosion inhibition for mild steel in Ca(OH)2 solution is studied by weight loss. These measurements indicate that (NCB) coordinates with the metal ion in a hexadentate manner through the sulfur and nitrogen atoms and the octahedral structure of these complexes is suggested. The anti-bacterial activity of the complexes against two types of bacterial Staphylococcus Aureus (+) and Escherichia Coli (_) for the metal complexes was higher than for free ligand (NCB).Keywords: Butanedioyl dichloride, Corrosion inhibition, Biological activity.
Secondary Prevention of Cardiovascular Disease in Patients after Myocardial Infarction: Pharmacoepidemiological Study Oxana Bogaevskaya
Journal of Global Pharma Technology Volume 12 Issue 01
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diseases of the cardiovascular system are among the main factors of premature death in the 21st century. However, the effectiveness of secondary prevention of coronary heart disease in developed Western countries and CIS countries can vary greatly. The purpose of this study is to evaluate the effectiveness of the application of international recommendations for secondary prevention in Russia in patients after myocardial infarction. The time of the study covers a 9-year period (2010-2019) in Cardiological Dispensary No. 3 of Moscow (Russia). A total of 9000 medical records were processed, of which 900 met the selection criteria. The average age of the patients was 61.5±9.7 years in an age range of 30-89 years. A survey of 606 doctors from private (1 group, 303 doctors) and state (2 groups, 303 doctors) dental clinics was conducted. Results the sample recorded a large scatter of data - from the moment the patient suffered a first heart attack - from a period of less than one year at a minimum to 43 years at a maximum. The average value of the interval was 4.6±5.3 years. Doctors on medical records most often paid attention to measuring blood pressure. 2-10 times less often (p≤0.001) met anthropometric indicators and analyzes for the lipid profile, and an order of magnitude less - control of the level of physical activity (p≤0.001). Differences were found between the therapy of patients depending on the type of medical institution - patients in cardiological dispensaries, on average, are 2-4 times more likely to receive prescription drugs (p≤0.001) compared with patients in polyclinics. It is noted that doctors, as a rule, do not note at the first visit to the patient in the cardiologic dispensary what kind of therapy he underwent in the clinic.  It is necessary to promote a healthy lifestyle, with a complete cessation of smoking and the use of alcoholic beverages. This will minimize the cost of expensive drugs for the population. On the patient’s medical records: the minimum occurrence rates of the following risk factors were recorded: smoking (3%), as well as physical activity (less than 1%) and overweight (25%). Medications are rarely prescribed: anticoagulants in 1% of medical records, as well as statins (10%). The use of an articain-containing anesthetic with a vasoconstrictor concentration of 1:200000 or without a vasoconstrictor during dental surgery helps to prevent the risk of complications of the cardiovascular system, especially with prolonged dental surgery, and especially in patients at risk.Keywords: Myocardial infarction, Risk factors, Secondary prevention, Invasive therapy, Cardiovascular disease.
Impact of Internet Banking Services on Customer Satisfaction: A Case Study of Bank Refah’s Customers, Northern Branches of Tehran Majid Taghavipour
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This research has been conducted with the aim of investigating the effect of internet banking services on customer satisfaction, a case study of the northern branches of Tehran using the research model presented by Heba Khalil Asfour and Shafiq Haddad (2014), a model for admitting factors affecting mobile banking acceptance and its impact on increasing customer satisfaction. Based on this model, mobile bank components such as reliability, efficiency, accessibility, privacy, flexibility, ease of use and trust lead to customer satisfaction with mobile banking services. Therefore, given the same platform for mobile banking and internet bank as well as the same variables affecting both cases, and finally the optimal model used in this paper, this model was selected to measure the impact of the above mentioned variables on the satisfaction of internet bank customers. In this research, a sample of 384 clients of the Northern Branches of Tehran, Refah bank who used Internet Banking services was investigated using a descriptive-survey research method. Most samples were selected from the statistical population using a two-stage cluster method and according to the information obtained from the researcher-made questionnaire. Research findings indicated that all of the Internet banking components mentioned above has a significant impact on satisfaction of service users, but according to the results of the regression test, privacy has been identified as the most important factor.Keywords: E-banking, Customer satisfaction, Internet banking, E-commerce, Customer satisfaction.
Health Promotion and Community Cadres’ Knowledge about the Medicine (DAGUSIBU) in the Community District of Yogyakarta, Indonesia Dyah Aryani Perwitasari
Journal of Global Pharma Technology Volume 10 Issue 12.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

DAGUSIBU is an acronym of to get, to use, to keep and to throw the medicine away appropriately in Indonesia. The Indonesia Pharmacist Association already launched this acronym to support the appropriate use of medicine. However, some efforts are needed to be conducted to understand about the dissemination of DAGUSIBU in community. This study is aimed to define the effectiveness of the health promotion in the increase of knowledge of the community cadres in one of community district in Yogyakarta, IndonesiaThis study used quasi experimental, one group pre-posttest design. The respondents were all community cadres in Muja Muju, Yogyakarta Indonesia. The health promotion with DAGUSIBU topic by the pharmacist was conducted as the health promotion media. The questionnaire was given to the respondents before and after the health promotion.We recruited 39 community cadres from Muja Muju Yogyakarta. Most of the respondents are female (94.9%), with the average of age is 54.5 years old. The community cadres’ knowledge increased significantly from 38.4 to 80.1 (p<0.001). Respondents’ characteristics, such as age, sex and education did not predict the increase of community cadres’ knowledge about DAGUSIBUThe health promotion of DAGUSIBU   conducted by pharmacist can improve the community cadres’ knowledge. This model can be used to disseminate DAGUSIBU effectively in community level.
Analysis of Fatty Acids of Liver in the Embryo and Adult of Domesticated Chicken Gallus Gallus Domesticus Nahla A. Al-Bakri
Journal of Global Pharma Technology Volume 11 Issue 05.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The fatty acids in the embryo's liver at ages (7, 11, 14 and 19) days incubation, small chicken aged (14) days after hatching and adult were analyzed, and found (5) fatty acids, the highest concentration of fatty acid in the adult of domesticated chicken and lowest concentration in small chicken age (14) days after hatching. Statistically, there were high significant differences at the probability level (P≤0.001) between all ages together, and the highest concentrations of Oleic acid (C18:1) and Linoleic acid (C18:2) were in embryo age (7) days incubation, while in embryo age (11) days incubation Stearic acid (C18:0) and α-Linolenic acid (C18:3) were higher concentration and Palmitic acid (C16:0) was the highest concentration in the adult. Stearic, Palmitic, Linoleic and α-Linolenic acids were recorded as the lowest concentration as well as in a small chicken age (14) days after hatching. Oleic acid had the lowest concentration in the embryo (19) days incubation, as well as α-Linolenic acid in the embryos age (7, 19) days incubation and the adult chicken did not record any concentration.Key words: Fatty acid, Chicken, Embryo, Liver.
The Effects of Stress on the Levels of Some Biochemical Parameters in Patients Intended to Surgery Hayder Abbas Alwan
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Stress is actually an appreciation that’s most emanating during sole reacts ending with unusual doings. it’s tense body’s tone going from rising in order to a confront including formation as far as tournament a hard position for a focal point, energy, moxie, along with intensive attentiveness. Trauma has to want to be been displayed ending by allowing significant property resting on the metabolic action (for case remains value, entire chunky, as a consequence of insulin also leptin levels). Stress stimulates the discharge of assorted hormone, which may end up in uprising glucose levels. Keyword: Stress, Surgery, Serum Insulin, Glucose, Bilirubin, Uric acid.
Potential Effectiveness of Essential Oil as Natural Food Preservatives Compared with Chemical Noor M. Witwit
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In this study, investigations were carried out to assess the efficiency of two plant essential oils; rosemary and thyme as natural food preservatives. The effect of the plant essential oils at concentrations of 1% and 2% was studied in the soft cheese against staphylococcus aureus and Escherichia coli at fridge temperature over a 5 day period. The essential oils performed well in the inhibition of Staphylococcus aureus  and E. coli  it is concluded that selected plant essential oils can act as potent inhibitors of  both microorganisms in a food product, Thyme was found to be very active against  E.coli in 2% and 1% (2.00, 2.66) respectively and S. aureus in 2% and 1% ( 7.66, 14.66) respectively followed by Rosemary in E.coli at 1% and 2% (4.33, 7.00) respectively also in S. aureus it effect in 2% more than 1% (5.00, 47.66) respectively.  At the same time we compared their effect with weak acid as chemical preservatives in citric acid was found to be more effective than thyme and rosemary in 1% and 2% in E.coli and S. aureus  (2.33, 1.00), (2.33, 1.33) respectively both essential oil and weak organic acid decreased growth of bacteria  significantly when compared with control.  Therefore, essential oils could be regarded as a source of food preservatives instead of chemical compounds.
Estimating the Amount of Methane Gas Generated from the Solid Waste using the Land GEM Software, Sistan and Baluchistan Mohammad Reza Narooie
Journal of Global Pharma Technology Volume 09 Issue 03
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The biodegradation of organic compounds in the waste produces different gases such as methane gas. Despite the adverse greenhouse effects of the methane, this gas has many fuel values. Since estimating the amount of methane gas produced from the waste can be an economic and useful way for more accurate control and management of waste disposal in the Sistan and Baluchistan Province, conducting this study is essential. In this research, after collecting required information such as population, growth rate, the results obtained from the physical and chemical analysis of the waste, geographic data and the desired disposal system using LandGEM software, the methane generation potential obtained from the waste disposal in the Sistan and Baluchistan Province was investigated. The results of this study showed that the methane production potential in the Sistan and Baluchistan Province is 147 m3/ton, and if the waste disposal process was started in 2006, the methane generation would be 567 m3/h in 2011 and by considering a 20-years period, this amount will be 3596 m3/h in 2026. Therefore, according to the presence of adequate landfill sites in the Sistan and Baluchistan Province, it can be concluded that the controlled burial along with the gas extraction equipment in this province is a useful way for the waste management.Keywords: Estimating, LandGEM, Methane, Solid Waste, Sistan and Baluchistan
Isolation and Diagnosis of Fungi Which Producing Aflatoxin B1in Chips in Local and Imported Markets Najaf Province R. A. Sahib
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study included isolating and diagnosing contaminated fungi from some local and imported chipsin Najaf Province,and to detect their ability to produce aflatoxin B1. The results showed that highest percentageof visible fungi namely are Aspergillusflavus, A. niger, A. glaucus, Alterneria sp., Fusarium sp. and A. terreusith ratio are (100, 95, 92,80, 75, 5.7) % respectively in Wejoh chips and these fungi appeared in all types of chips under study. The results of the frequency of the same fungi in the wejoh chips are (80,70, 68, 52, 50,2) % respectively.A.flavus is more visible and frequently in thesame types of chips,and preferable sabouraud dextrose (agar,broth) medium to growth. Primary result proved that  A. flavus producing aflatoxin B1in Thinlayerchromatography (TLC) which appear blue spot of aflatoxin B1 with rate of flow (RF) is 56 % under UV light expose with wavelength of (365 nm).High performance liquid chromatography (HPLC) results show that retention time or major peak of standard aflatoxin B1 located at 10.54 minutes, while a filter extract of A. flavusis10.75 which  identifies with aflatoxin B1 standardwhich located  in the same area.Keywords: Chips, A. flavus, Aflatoxin B1, SEM, TLC, HPLC.
Formulation, Evaluation and Release Mechanism of Ketoconazole Microsponge by Liquid-Liquid Suspension Polymerization Method S. Parimalakrishnan
Journal of Global Pharma Technology Volume 11 Issue 11 (2019) November 2019
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The aim of the present study is to formulate a microsponge based release system contains ketoconazole for controlled release of drugs for an effective fungal treatment. Compatibility study involving drug and polymer mixture done by FTIR and was initiate to be compatible. Ketoconazole loaded microsponges were prepared by liquid-liquid suspension polymerization method using ethyl cellulose and hydroxypropyl methylcellulose as polymers with different drug polymer ratios. Later, formulated microsponges were characterized. The particle size was measured by SEM, entrapment efficiency by assay and in vitro drug release profile by dissolution. The effect of preparation variables such as a drug to polymer ratio and stirring speed on the physical characteristics of microsponges is examined. The formulated microsponges were spherical and porous, with a mean particle size of 100μm at 400 magnifications. 87.6% of drug was entrapped in the system and 89.40% of drug was released at 12th hour from FII. From the above findings, we conclude that microsponges were prepared successfully and evaluated. The evaluation report shows that the sizes of the particle are within the range and controlled release of drug was achieved. This indicates that polymer choosen for the study is appropriate. The mathematical kinetic modeling shows that FII formulation undergoes zero order kinetic and follows Higuchi model, which follows diffusion mechanism in the release of drugs.Keywords: Ketoconazole, Microsponges, Ethyl cellulose, Hydroxypropyl methylcellulose, Liquid-Liquid suspension polymerization.

Filter by Year

2010 2026


Filter By Issues
All Issue Volume 18 Issue 01 (2026) Jan. 2026 Volume 17 Issue 12 (2025) Dec. 2025 Volume 17 Issue 11 (2025) Nov.2025 Volume 17 Issue 10 (2025) Oct. 2025 Volume 17 Issue 04 (2025) April 2025 Volume 17 Issue 03 (2025) March 2025 Volume 17 Issue 02 (2025) Feb. 2025 Volume 17 Issue 01 (2025) Jan 2025 Volume 16 Issue 12 (2024) Dec. 2024 Volume 16 Issue 11 (2024) November 2024 Volume 16 Issue 10 (2024) October 2024 Volume 16 Issue 09 (2024) September 2024 Volume 16 Issue 08 (2024) August 2024 Volume 16 Issue 07 (2024) July 2024 Volume 16 Issue 06 (2024) June 2024 Volume 16 Issue 05 (2024) May 2024 Volume 16 Issue 04 (2024) April 2024 Volume 16 Issue 03 (2024) March 2024 Volume 16 Issue 02 (2024) February 2024 Volume 16 Issue 01 (2024) January 2024 Volume 14 Issue 05 (2022) May 2022 Volume 13 Issue 05 (2021) May 2021 Volume 13 Issue 04 (2021) April 2021 Volume 13 Issue 03 (2021) March 2021 Volume 13 Issue 02 (2021) Feb. 2021 Volume 13 Issue 01 (2021) Jan. 2021 Volume 12 Issue 12 (2020) Dec. 2020 Volume 12 Issue 11 (2020) Nov. 2020 Volume 12 Issue 10 (2020) Oct. 2020 Volume 12 Issue 09 (2020) Sept. 2020 Volume 12 Issue 08 (2020) Aug. 2020 Volume 12 Issue 07 (2020) July 2020 Volume 12 Issue 06 (2020) June 2020 Volume 12 Issue 05 (2020) May 2020 Volume 12 Issue 04 (2020) April 2020 Volume 12 Issue 03 (2020) March 2020 Volume 12 Issue 02 (2020) Feb. 2020 Volume 12 Issue 01 (2020) Jan. 2020 Volume 12 Issue 08 Volume 11 Issue 12 (2019) December 2019 Volume 11 Issue 11 (2019) November 2019 Volume 11 Issue 10 (2019) October 2019 Volume 11 Issue 09 (2019) September 2019 Volume 11 Issue 09: (2019) September 2019 Volume 11 Issue 08 (2019) Aug. 2019 Volume 11 Issue 07 (2019) July 2019 Volume 11 Issue 06 (2019) June 2019 Volume 11 Issue 05 (2019) May 2019 Volume 11 Issue 04 (2019) April 2019 Volume 11 Issue 03 (2019) March. 2019 Volume 11 Issue 02 (2019) Feb. 2019 Volume 11 Issue 01 (2019) Jan. 2019 Volume 11 Issue 2: 2019 Volume 10 Issue 12. Volume 11 Issue 6. Volume 10 Issue 12 (2018) December 2018 Volume 10 Issue 11 (2018) November 2018 Volume 10 Issue 10 (2018) October 2018 Volume 10 Issue 09: (2018) September 2018 Volume 10 Issue 08: (2018) August 2018 Volume 10 Issue 07: (2018) July 2018 Volume 10 Issue 06: (2018) June 2018 Volume 10 Issue 05: (2018) May2018 Volume 10 Issue 04: (2018) April 2018 Volume 10 Issue 02: (2018) Feb 2018 Volume 10 Issue 01: (2018) Jan. 2018 Volume 10 Issue 10: 2018 Volume 10 Issue 01 Volume 09 Issue 12 Volume 09 Issue 11 Volume 9 Issue 11 . Vol. 9 Issue 7 : 2017 Volume 9 Issue 10 Volume 09 Issue 09 Volume 09 Issue 08 Volume 9 Issue 07 Volume 09 Issue 05 Volume 09 Issue 04 Volume 09 Issue 03 Volume 09 Issue 02 Volume 08 Issue 11 Volume 08 Issue 07 Volume 08 Issue 06 Volume 08 Issue 05 Volume 08 Issue 04 Volume 08 Issue 03 Volume 08 Issue 02 Volume 08 Issue 01 Volume. 9 Issue 6 Volume 08 Issue 10: (2016) October 2016 Volume 08 Issue 09: (2016) September 2016 Volume 12 Issue 01 Volume 11 Issue 07 Volume 11 Issue 05. Volume 11 Issue 04. Volume 11 Issue 03 Volume 11 Issue 01. Volume 08 Issue 08 Volume 04 Issue 02: (2012) February 2012 Volume 03 Issue 06: (2011) June 2011 Volume 03 Issue 04: (2011) April 2011 Volume 02 Issue 10: (2010) Oct.2010 Volume 02 Issue 07: (2010) July 2010 Volume 02 Issue 05: (2010) May 2010 Volume 02 Issue 03: (2010) March 2010 More Issue