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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
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The Impact of the Educational Program Using Teaching Aids in Teaching the Skills of Service Receiving and Court Defending for the Students the Volleyball Majid Hameed Merzah
Journal of Global Pharma Technology Volume 10 Issue 07: (2018) July 2018
Publisher : Journal of Global Pharma Technology

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Abstract

The coaches and experts interested in preparing the volleyball teams from the physical, skill, planning and psychological aspects of their teams, on a set of bases, the most important of which are the basic skills which vary in level of complexity and complexity from one game to another .Based on this sense of importance of these skills, which reduces efforts, shortens time and material possibilities, and makes early learning processes a little more erroneous because errors at these stages, if developed, are difficult to correct. And through the researcher's practice of this game found that these skills are still taught in traditional ways, and educational curricula in the general sphere of volleyball lacks the use of aids and devices that help to accelerate and stabilize the processes of education and consolidate the differences between these skills, the use of traditional methods of learning, which It is not possible to arrive at a precise description or measurement of learning, and non-objective evaluation is accompanied by many errors in accurate monitoring of the movement parts.The research objects:Find educational aids to teach students the skills of service receiving and paying volleyball students.Learning about the impact of the learning program using some educational aids in teaching the skills of service receiving and paying students with volleyball.The researchers used the experimental method in the style of equal groups to suit the problem. The research society determines the students of the second stage in the Faculty of Physical Education and Sports Sciences at the University of Karbala for the academic year 2016-2017 Division (A, B, C) and the number of (82) (24) students, divided into two groups of each group (12) students.The most important conclusions were:The proposed learning program using innovative teaching methods has a positive impact on teaching service receiving skills.The proposed learning program using innovative teaching aids has a positive impact on the teaching of court defending skill.Keywords: Educational program, Teaching aids, Receiver service and defending of pitch skills.
Effect of Different Temperature in DNA State of Teeth Samples Mona N. Al-Terehi
Journal of Global Pharma Technology .
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Abstract

There are many forensic  techniques used today that benefit to identify human remains from mass grave, explosion, fire, disasters, first step of DNA analysis was DAN extraction from biological evidence ,DNA retraction must be free from contamination as possible. The source of DNA is varying numerous as blood, saliva, nail, hair, bone, skin, urine and teeth. All source of DNA can be isolated from any living or dead organism even from ancient specimens. The aims of this study was evaluated DNA  states in teeth samples which exposure to heat at different time, Teeth sample were collected from 30 female from Q adisiyah province \ Iraq. Extraction of DNA were made by Gene MATREX UROX Bone DNA purification kit ,27teeth were burn at 100°C,500°C,1000°C  for(10,30,60) minutes,3 sample of teeth were extraction without exposure to heat as control. The results show that genomic DNA was obtained only in samples exposure to 100°Cand 500°C, no DNA was obtained from samples at 1000°C. The amplification of Exon -7 of gene CYP1A1 by PCR show that 20% of samples was amplified in the 100 C and 500 C grope and no amplification appeared in 1000 C samples. We concluded that DNA was more stable in teeth sample under different temperature, furthermore sample under 1000 C need more investigation like RT-PCR to detect DNA state in low concentrations and purity.Keywords: DNA states, Forensic evidence, Teeth samples PCR.
Ethanolic Extracts of Young Papaya Seed (Carica papaya, Linn) Decrease Spermatocytes, Leydig Cells, and Androgen Receptor of Leydig Cells of Adult Mice (Mus musculus) Christopher Ryalino
Journal of Global Pharma Technology Volume 12 Issue 01
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Abstract

Background: Uncontrolled population growth is one of the problems in Indonesia. Among the various types of wild plants that can be used as anti-fertility drugs are papaya plants. This study aims to determine the effect of extracts on the number of spermatozoa, Leydig cells and androgen receptor (AR) expression on Leydig cells as an anti-fertility mechanism.  Materials and Methods: This was an experimental, randomized posttest-only controlled group study. We used a total of 36 Wistar rats as the subjects of this study. The rats were classified equally into two groups by simple random sampling method. Group E rats received 0.5 mL ethanol extract of papaya seeds for 50 days (orally), and the rats in Group C (control) received 0.5 cc aquabidest for 50 days. Results: The treatment group showed a decrease in the number of spermatozoa (201.86 vs. 94.3, p <0.001), a decrease in the number of Leydig cells (7.61 vs. 3.32, p <0.001), and decreased AR expression of Leydig cells (46.19 vs. 18.48, p <0.001) compared to the control group. Conclusion: ethanol extracts of young papaya seeds significantly reduce the number of spermatocytes, Leydig cells, and the AR expression of the Leydig cells.Keywords: Young papaya seed, Male anti-fertility, Androgen receptor, Leydig cells.
The Effect of Muscular Endurance Exercises According to Superset Theory in some Physiological Abilities and Completion of Running 800 Meters Advanced Suhad Qasem Al-Moussawi
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

This study aimed to identify the effect of muscular endurance in the development of some physiological abilities to achieve an 800-meter run. The researchers hypothesized that there was a positive effect of the Super Set muscular endurance exercises in advanced race runners. The researchers used the experimental approach to suitability and the nature of the research. The study sample consisted of (10) players divided equally into experimental and control groups. The experimental group used muscle training exercises in Superset to develop physiological variables such as anaerobic and aerobic abilities and the concentration of lactic acid in blood. The control group In addition to the physiological variables such as the measurement of the levels of lactic acid in the blood (before and after) the brown effort, the experiment lasted (10) weeks and (3) units The results of the study showed that there were significant differences in some variables, such as the arithmetic mean, the standard deviation, the torsion coefficient, and the t-test of the interrelated samples. Physiology and the concentration of lactic acid in blood between the experimental and control groups. The results of the study showed the existence of random differences between the two groups in the post-test of the concentration of lactic acid before the effort.Keywords: Athletics, Running 800 meters, Superset exercises, Anaerobic and aerobic abilities and lactic acid concentration.
Synthesis, Characterization and Biological Evaluation of Esters Derived from Sulfamethoxazole Drug Inas S. Mahdi
Journal of Global Pharma Technology Volume 11 Issue 03
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Abstract

A series of novel esters compounds have been prepared from the reaction of sulfamethoxazole drug with α-chloro acetyl chloride then reaction of the resulting compound with various carboxylic acids and carboxylic drugs. The modern ester has been diagnosed by 1HNMR, FTIR spectral data and their physical properties and some of them were screened for their antibacterial activity.Keywords: Sulfamethoxazole, Esters, Antibacterial activity.
Implementing Lifestyle Management Using Health Promotion Model Approach Khamida Khamida
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Abstract

Introduction: There are problem-related to student’s health behavior in Islamic boarding schools, they do not washing their hand before they have their meals, hanging wet clothes in their room,  and they do not really care about toilet hygiene.  The aim of this research was to know the effect of peer group support to student's lifestyle management using health promotion model approach. Method: The design was quasi-experimental, pre-post-test control group the population were students who stayed in Islamic boarding school in Surabaya and Sidoarjo, and the total sample was 100 students, 50 in control group, 50 in the intervention group, the sample taken by simple random sampling.  In the intervention group, they’ve got health education and peer group support while the control only got health education by giving a student lifestyle management module. The independent variable was peer group support and the dependent variable Student's lifestyle management. The data were taken by the questionnaire and were analyzed by the Mann Whitney test. Result: The result showed that after the treatment, students in the intervention group have Mean 23.28 SD 4.83 meanwhile the control group has SD 4.27 and Mean 4.38. Conclusion: It means that peer group support could change lifestyle management based on the health promotion model. The leaders or caretakers of Islamic boarding schools are expected to continue to monitor the behavior of students in implementing the management of the student's lifestyle and activate the boarding school health center.Keywords Student, Lifestyle management, Islamic Boarding School Peer Support Group.
Adsorption of 1- (2--Hydroxy - 4--Nitrophenyl azo)-2- Napthol Dye onto the Cement Kiln Dust (CKD) Nemah Sahib Mohammed Hussian
Journal of Global Pharma Technology Volume 10 Issue 01: (2018) Jan. 2018
Publisher : Journal of Global Pharma Technology

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Abstract

The adsorption of 1-(2¯- Hydroxy-4¯-nitrophenyl azo) -2-naphthol dye onto the Cement Kiln Dust (CKD) was studied in the temperature range 298-328K. The sorption process was examined in terms of its equilibria and kinetics. Batch adsorption experiments were conducted to evaluate the percentage removal of 1-(2--Hydroxy -4- - nitrophenyl azo)-2-napthol onto CKD waste at operation conditions of sorbate concentration, pH, contact time, sorbent dose. Time-dependent experiments for the removal efficiency required a shortest contact time, i.e , binding to the CKD was rapid and occurred within 25 min. Adsorption isotherms equations were tested for all of Langmuir, Freundlich, Temkin,3 Dobinin-Radushvich, and Elovich. The equilibrium adsorption data were fitted to Freundlich and Temkin isotherms at 298K. Adsorption followed Intra – partical - diffusion rate kinetics.   Thermodynamic parameters ΔG*, ΔH*, ΔS* and Ea were computed, and showed that the adsorption process onto CKD was exothermic and non-spontaneous. Also adsorption studies suggest that physisorption might be the major mode of adsorption and CKD expressed as low affinity for removal of 1-(2¯- Hydroxy-4¯-nitrophenyl azo) -2-naphthol Dye onto the Cement Kiln Dust  that the high percentage removal was found ≈50%  at 298K , pH=6.Keywords: Cement Kiln Dust; Azo dyes; Adsorption isotherms; Kinetic study; Thermodynamic study.
The Employment of Standard Addition Method for the UV Spectrophotometric Assay of Diclofenac Alkaline Salts in Variant Pharmaceutical Dosage Forms Zaid Mahdi Jaber Al-Obaidi
Journal of Global Pharma Technology .
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Abstract

Objective: The standard addition method is widely utilised in the drug analysis protocols. The objective of this study is to perform a fast, easy, economy, and reliable method for the quantitation of diclofenac in different pharmaceutical dosage forms utilizing standard addition method with the employment of UV-Vis spectrophotometric technique. Methods: Four different dosage forms of diclofenac were selected to be analysed. These include: tablets, ampules, Emulgel, and powders for oral use. After preparing the samples with well-conducted procedures, the prepared samples were inoculated with predetermined spikes of the standards. Consequently, these prepared samples were analysed employing UV-Vis techniques. Results: As a result, the plotted standard curves for Cataflam, Voltaren Emulgel, Voltafast sachets, and Voltaren ampule showed good linearity with regression coefficients of 0.9984, 0.9988, 0.9981, 0.9992, and 0.9996 for respectively. The Limit of detection (LOD = 3SD) and Limit of quantification (LOQ = 10SD) were calculated for each dosage form. With the aid of the straight line equations, sample concentration was estimated for both techniques. The percent amount was found to be 99.04%, 105.5%, 98.64%, and 99.32% in respective order to the mentioned four diclofenac salts. Conclusion: The authors conclude that the standard addition method utilised in UV-Vis was as accurate, precise, fast, and economy, thus, can be used in routine laboratory drug-analyses.Keywords: Standard addition, Diclofenac sodium, Diclofenac potassium, Diclofenac diethylamine, Voltaren, Emulgel, Voltafast, Cataflam, UV-Vis, Diclofenac quantification.
Evaluation PAHs Contamination Level in the Breast Milk of Women in Al-Diwaniyah city, Iraq- a Case Study Faiq F. Karam
Journal of Global Pharma Technology Volume 11 Issue 07
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Abstract

Human milk is an important bio indicator for the exposure with some pollutants like polycyclic aromatic hydrocarbons. Breast milk samples from 68 women were live in Al-Diwaniyah city were collected in this study. Thirteen of poly cyclic aromatic hydrocarbons were investigated in all samples using gas chromatography coupled with mass spectroscopy. The samples were divided into three groups according to the age range (less than 20 years, 20-30 years and 31-40 years). Eight samples were the control for this study from the rural mothers. The mothers were all them non-smokers. The samples were collected during 2017 from different regions located in Al-Diwaniyah City.Keywords: Breast milk, Polycyclic aromatic hydrocarbons, Pollution in Al-Diwaniyah City, Gas Chromatography, Exposure to pollutants.
Professional Self-Concept Model on Working Productivity of Clinical Nurses Kusnanto Kusnanto; I Gede Juanamasta; Slamet Riyadi Yuwono; Yulastri Arif; Kadek Ayu Erika; Hidayat Arifin
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
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Abstract

Introduction: The nurses' professional self-concept is concerned with how individuals perceive themselves as professionals and in nursing is about what nurses feel about themselves as nurses. The purpose of this study is to develop a professional self-concept model on the productivity of the nurse's work. Methods: An explanatory design with cross-sectional approach. Samples were 311 nurses in inpatient room with simple random sampling. Data analysis using Partial Least. Organizational aspects (0.4397). Results: Characteristics of the work (0.1978) and the organizational environment (0.5391) were affects the nurses' professional self-concept. The self-concept of professional nurses affects work productivity (0.4953). Conclusion: Organizational characteristics, work characteristics, and organizational environment have a relationship with professional self-concept of nurses. Furthermore, the self-concept of professional nurses has a relationship and can enhance nurse work productivity. Professional self-concept nurses form a professional identity in nurses who increase nurse productivity at work.

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