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INDONESIA
Jurnal Penyakit Dalam Indonesia
Published by Universitas Indonesia
ISSN : 24068969     EISSN : 25490621     DOI : https://doi.org/10.7454/
Core Subject : Health,
Medicine & Pharmacology
Jurnal Penyakit Dalam Indonesia contains the publication of scientific papers that can fulfill the purpose of publishing this journal, which is to disseminate original articles, case reports, evidence-based case reports, and literature reviews in the field of internal medicine for internal medicine and general practitioners throughout Indonesia. Articles should provide new information, attract interest and be able to broaden practitioners insights in the field of internal medicine, as well as provide alternative solutions to problems, diagnosis, therapy, and prevention.
Arjuna Subject : Kedokteran - Kedokteran Internal
Articles 414 Documents
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Factors Associated with Late Referral in End Stage Renal Disease Patients at Dr. Cipto Mangunkusumo Hospital Lydia, Aida; Rachmaningrum, Grecia; Shatri, Hamzah; Nugroho, Pringgodigdo
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Relationship between Total Session of Hyperbaric Oxygen Therapy as Adjuvant Therapy with Diabetic Foot Ulcers Improvement in Dr. Mintohardjo Naval Hospital in The Year 2016−2018 Andrisha, Naufal Hilmi; Savitri, Pritha Maya; Bustamam, Nurfitri
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Introduction. Diabetic foot ulcers (DFU) are a common complication of diabetes mellitus (DM). High rates of amputation risk and mortality in DM patients with DFU as well as the use of conventional therapies that often fail to improve the DFU condition cause an adjuvant therapy such as hyperbaric oxygen therapy (HBOT) to be used. HBOT is known can facilitate wound bed closure and reduce the amputation rates in diabetic gangrene foot. This study aimed to determine the relationship between total sessions of HBOT as adjuvant therapy with an improvement of DFU patients. Method. A cross-sectional study was conducted among DFU patients who were given HBOT as adjuvant therapy in Dr. Mintohardjo Naval Hospital in the year 2016–2018. Data were collected from the medical record. The statistical analysis used in this study was the Friedman test to assess whether there was a relationship between the total session of HBOT with the DFU improvement. Wilcoxon post-hoc test was performed to provide the treatment group with the best DFU improvement. Results. There were 20 subjects in this study. To assess the best treatment group in DFU improvement, a comparison between the treatment groups under 10 sessions and above 10 sessions with other treatment groups was made. Friedman test with p-value = 0,001 indicates that there was a relationship between total session of HBOT as adjuvant therapy with an improvement of DFU. Based on Wilcoxon post-hoc test, the treatment groups that were statistically significant in DFU improvement was a treatment group above 10 sessions with p-value = 0,001. Conclusion. The total session of HBOT as adjuvant therapy above 10 shows that it is the most significant improvement for DFU with a decrease in the ulcer degree and reduced wound size.
Advanced Directives in Palliative Care Shatri, Hamzah; Faisal, Edward; Putranto, Rudi; Sampurna, Budi
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Initially palliative care is emphasized at the end of life, but the right thing is to begin identifying palliative care needs when the disease is diagnosed. Palliative care is the treatment needed to improve the quality of life of patients and their families that suffering from life threatening and progressive disease such as cancer, non-cancer diseases, and HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndrome). Palliative care decision must be in place from the beginning of treatment, so the patient’s preferences are met. The goals of this care are to reduce physical, social, psychological, and spiritual suffers. Further treatment plan is based on discussion between patient, family, and health care worker. The final result is identification and decision that can be written in advanced directives.
Change of Coagulation Status in Solid Cancer Patients Undergoing Chemotherapy in Indonesia: A Prospective Cohort Study Sutandyo, Noorwati; Setyawan, Lyana
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 1
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The Relationship between Serum Calcidiol Deficiency and The Degree of Sarcopenia in Elderly Communities in Surabaya Indirayani, Hemma Wahyuda; Widajanti, Novira; Firdausi, Hadiq
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 1
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Prediksi Respons Terapi Leukemia Granulositik Kronis: Skor Mana yang Lebih Baik? Mulansari, Nadia Ayu
Jurnal Penyakit Dalam Indonesia Vol. 6, No. 4
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Leukemia granulositik kronik (LGK) merupakan suatu keganasan myeloproliferatif dengan karakteristik ditemukannya kromosom Philadelphia (Ph). Kromosom Ph ini disebabkan oleh translokasi resiprokal antara kromosom 9 dan 22 [t(9;22)] dan terbentuknya fusi gen BCR-ABL1. Fusi gen tersebut akan menghasilkan suatu protein yang menderegulasi aktivitas dari tirosin kinase (p210) yang berperan pada patogenesis LGK.
Comparison of Socal Score and Hasford Score Against the Response of Imatinib Mesylate Therapy in Patients with Chronic Granulocytic Leukemia in dr. Saiful Anwar Hospital Malang Somarnam, Somarnam; Machsoos, Budi Darmawan; Hermanto, Djoko Heri
Jurnal Penyakit Dalam Indonesia Vol. 6, No. 4
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Introduction. The Socal and Hasford scores developed before the era of tirosine kinase inhibitor (TKI) therapy to provide predictions and prognosis for the results of therapy for chronic myeloid leukemia patients (CML). Until now the superiority of Socal and Hasford scores is still debated in predicting the results of therapy in the era of TKI. Imatinib mesylat is a first line TKI in the treatment of CML. This study aims to determine the superior predictive score in predicting hematological and molecular response of patients treated with imatinib mesylate. Methods. A survey study was conducted with data taken retrospectively from medical records. Subjects were chronic phase LGK patients who had at least been given imatinib mesylate therapy for 12 months. Calculation of Socal and Hasford scores was carried out based on patient data when first receiving Imatinib. To see the difference in distribution between the two scores, a marginal homogeneity statistic was used. To see the process of changing the response of patients treated with Imatinib, a suitability test using chi-square and Fischer was conducted with a significant p value, p 0,05. Conclusion. There was no significant difference between Hasford and Socal scores in predicting hematological responses and molecular responses of chronic CML patients. Socal scores and Hasford scores can be used to predict hematological and molecular responses in chronic CML patients treated with imatinib mesylate.
Comparison of Mortality between Intravenous Albumin and No Intravenous Albumin in Sepsis Patients with Hypoalbuminemia Conditions and Factors that Influence the Mortality of Sepsis Patients Marzuki, Mochammad Jalalul; Supriono, Supriono; Pratomo, Bogi; Mustika, Syifa
Jurnal Penyakit Dalam Indonesia Vol. 6, No. 4
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Introduction. Hypoalbuminemia is a strong predictor of mortality in nonoperative and operative patients. Albumin plays a role in maintaining oncotic pressure in critical conditions such as sepsis. The administration of exogenous Human Serum Albumin (HSA) in sepsis with hypoalbuminemia conditions is still controversial with varying outcomes.This study aimed to know the mortality ratio between intravenous albumin administration and no intravenous albumin administration in sepsis patients with hypoalbuminemia conditions and also to know the factors that influence the mortality of sepsis patients. Methods. An observational study with a prospective approach involving 75 research subjects aged >18 years with sepsis accompanied by hypoalbuminemia (<2.5 g/dL) treated in the high care unit of RSUD dr. Saiful Anwar Malang during the period 1 September 2018-31 August 2019. Subjects were divided into two groups namely albumin and nonalbumin groups. Both groups were followed during hospitalization until they discharged or died. Differences in mortality between the two groups were analyzed by chi square bivariate test. The most influential factors on mortality were analyzed by multivariate binary logistic regression tests. Results. There were 39 people (52%) from the albumin group and 36 people (48%) from the non-albumin group. Difference in mortality between albumin and nonalbumin groups {25 (64.1%) vs 16 (44.4%) with OR 2, p=0.138} means there was no statistically significant difference. Factors that influence mortality included: SOFA score (OR 34.27, p <0.001), MAP value (OR 8, p<0.001), septic shock (OR 4.31, p=0.03), diabetes mellitus (OR 0.28, p=0.009), respiratory failure (OR 8.02, p <0.001), decreased of consciousness (OR 64.75, p <0.001), cardiovascular failure (OR 6, p <0.001), hematological failure (OR 3.05, p=0.027). The most dominant factor affecting mortality in sepsis patients is decreased of consciousness (OR 2.67, p=0.001). Conclusion. The administration of albumin transfusion did not make a significant difference in the incidence of mortality in sepsis patients with hypoalbuminemia. The most influential factor on mortality of sepsis patients is decreased of consciousness.
Tenofovir dan Gangguan Fungsi Ginjal pada HIV Hustrini, Ni Made
Jurnal Penyakit Dalam Indonesia Vol. 6, No. 3
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Bile Reflux Gastritis Patient Profile in DR. Saiful Anwar Malang Hospital Nurisa, Fadhila; Supriono, Supriono
Jurnal Penyakit Dalam Indonesia Vol. 6, No. 3
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Introduction. Bile reflux gastritis is bile reflux to gaster with fullness sensation, uncomfort, nausea, and vomiting. Bile reflux gastritis usually happens after surgery, as partial gastrectomy, truncal vagotomy, pyloroplasty, cholecystectomy, or sphinchteroplasty. This study aimed to determine the description of endoscopic of patients with bile reflux gastritis and the location of abnormalities found in endoscopy patient at Saiful Anwar Hospital Malang. Methods. Data were taken from the medical record of endoscopy patient in Saiful Anwar Hospital Malang from 2012 January the 1st until 2016 December the 31st that fulfill bile reflux gastritis inclusion criteria. Abnormality location divided near and far from pyloric. The location that near from pyloric is antrum, pyloric, duodenum, and distal duodenum. The location that far from pyloric is esophagus, esophagogastric-junction, fundus, corpus, and angulus. Results. Among 3,491 endoscopic patients, there were 1,949 gastritis patients (55.83%). A total of 1,949 gastritis patient, 124 fulfill bile reflux gastritis criteria. Four exclusion criteria (incomplete data), 120 patients bile reflux gastritis, 62 men (51.67%) and 58 women (48.33%). Hyperemia mostly at antrum (96), erosion mostly at antrum (43), edema mostly at pyloric (18), ulcer mostly at antrum (14). Presentation of hyperemia, erosion and edema far from pyloric as many as near the pyloric. More ulcer found near the pyloric (75.68%). Conclusions. Hyperemia, erosion, and ulcer mostly found at antum, edema mostly found at pyloric. Hyperemia, erosion, and edema spread in all of the parts. More ulcer found near the pyloric.

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