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Evy Yunihastuti
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redaksi.jurnalpenyakitdalam@ui.ac.id
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Departemen Ilmu Penyakit Dalam, FKUI/RSCM Jln Diponegoro No.71, Jakarta. 10430
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Kota depok,
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INDONESIA
Jurnal Penyakit Dalam Indonesia
Published by Universitas Indonesia
ISSN : 24068969     EISSN : 25490621     DOI : https://doi.org/10.7454/
Core Subject : Health,
Jurnal Penyakit Dalam Indonesia contains the publication of scientific papers that can fulfill the purpose of publishing this journal, which is to disseminate original articles, case reports, evidence-based case reports, and literature reviews in the field of internal medicine for internal medicine and general practitioners throughout Indonesia. Articles should provide new information, attract interest and be able to broaden practitioners insights in the field of internal medicine, as well as provide alternative solutions to problems, diagnosis, therapy, and prevention.
Articles 414 Documents
Relationship between Symptoms of Depression and Anxiety with Major Adverse Cardiac Event in 7 days in Patients with Acute Coronary Syndrome in Cipto Mangunkusumo Hospital Sari, Diah Pravita; Mudjaddid, E; Ginanjar, Eka; Muhadi, Muhadi
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 4
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Introduction. One of the causes of death in acute coronary syndrome is the occurrence of complication known as major adverse cardiac events (MACE). There are several predictors of the occurance of MACE in patients with ACS, including depression and anxiety. Thi study aimed to determine the association between depression and anxiety with major adverse cardiac events within 7 days in patients with acute coronary syndrome. Methods. Study with prospective cohort design to examine the association between depression and anxiety with MACE within 7 days of ACS patients, using HADS questionnaires on ACS patients undergoing treatment at ICCU, Hospitalization RSCM in January - May 2018. Bivariate analysis was performed to calculate the risk ratio (RR) of MACE occurrence within 7 days in the depression and anxiety group using SPSS. Results. Obtained number of subjects who meet the inclusion criteria of 114 people. Depression was obtained in 7% of subjects, Anxiety was obtained in 28,95% of subjects, and MACE was obtained in 9.6% of subjects. In the Depression group, MACE 7 days occurred in 12.5% of subjects. In the Anxiety group, MACE 7 days occurred in 21,2% of subjects. In bivariate analysis, Anxiety increased the risk of MACE within 7 days in patients with ACS, with relative risk (RR) of 4,2 (IK 1,34 – 13,70). Conclusions. Anxiety in patients with ACS is an independent predictor of MACE within 7 days and increases the risk of a 7 day MACE. There was no correlation between depression and MACE within 7 days in patients with ACS.
Correlation between History of Fall and Timed Up and Go Test in Geriatric Nurmalasari, Mifta; Widajanti, Novira; Dharmanta, Rwahita Satyawati
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 4
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Introduction. Fall is the global major problem in geriatrics as it causes physical and physicological impairment, even leads to mortality. Timed up and go test (TUG) is the screening method which commonly used in medical practice as standard examination to assess mobility, balance, and fall risk.This study aimed to determine the correlation between TUG and history of falls in geriatric patients at General Hospital Dr. Soetomo Surabaya, Indonesia. Methods. A cross-sectional study was conducted among geriatric patients in Dr. Soetomo hospital with criteria ≥ 60 years old, mini mental state examination (MMSE) score ≥ 17, did not suffer from hemiplegic stroke, and did not use walking aids. Subjects with these criteria were interviewed to know the fall history from the past 12 months, level of education, and comorbidity. Then the subjects carried out MMSE assessment, BMI (body mass index) measurement, and TUG assessment. Statistical analysis was done with Fisher exact test.. Results. A total of 73 subjects participated in this study of which 56.16% were women. Among 73 subjects, 18 subjects had a history of falls and 72.22% of them were women. The Fisher test results showed a significant relationship between history of falls and TUG with p value= 0.048 and a contingency coefficient= 0.305. Conclusion. There was weak correlation between history of falls and TUG. Subsequent studies need to add and select samples with uniform distribution of characteristics, so that the results could represent the entire elderly population at General Hospital Dr. Soetomo Surabaya, Indonesia.
Cause of The Low Positivity of Blood Culture in Septic Patients Yana, Krishna; Alisjahbana, Bachti; Hartantri, Yovita
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 4
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Introduction. Sepsis due to bacterial infection is one of the main causes of high disease morbidity and mortality. Management of sepsis, the detection of bacteriemia by examination of blood cultures has an important role, but until now the positivity of blood culture results at Hasan Sadikin Hospital (RSHS) is still low (13.45%). The purpose of this study was to determine profile the causes of low positivity of blood culture results in sepsis patients in RSHS. Methods. A cross sectional study was conducted on sepsis patient treated in Emergency Un it (ER) and inpatient of Hasan Sadikin hospital Internal Medicine from December 2016 until April 2017. This study collects patient clinical information, laboratory, history Administration of antibiotics, and techniques of examination of bacterial blood cultures in sepsis patients. Results. During the study period 179 subjects were obtained. The subject mainly uses the Health Guarantee Agency (BPJS) for financing. The positivity of blood cultures was found to be 24%. The mean leukocyte count on positive blood culture results was 18,100 / mm3 and there were 79.07% cultures with Neutrofil Limfosit Count Ratio (NLCR) >10. The time for taking blood cultures is mainly done at> 6 hours after admission. The number of blood cultures is taken at least once. The amount of blood volume in each culture tube is mostly 5 cc. Taking blood cultures is mainly carried out by competent nurses who have not received blood culture taking training. Conclusions. The positive results of blood culture in septic patients in RSHS are still low. Taking blood cultures should be carried out in accordance with the guidelines, which consist of not giving antibiotics before taking blood culture, taking blood time at admission, the number of blood taken for culture >1 time, the amount of blood volume in a culture tube is at least 10 cc, use 2 types of antiseptics, the use of antiseptics on culture bottle caps, the time lag between antiseptic action and blood collection for culture. It is necessary to monitor the factors that influence the positivity of blood cultures in septic patients. Researchers also recommend training and policy improvements to improve blood culture positivity.
Cedera Hati Hipoksik pada Infark Miokard Akut Jasirwan, Chyntia Olivia Maurine
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 3
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Hypoxic Liver Injury as Predictor of Major Adverse Cardiac Events in Acute Myocardial Infarction patients admitted to Intensive Coroner Care Unit of Cipto Mangunkusumo National General Hospital Muhadi, Muhadi; Prihartono, Nurhayati Adnan
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 3
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Introduction. Major adverse cardiac events (MACE) is a complicating myocard infarct which consist of acute heart failure, cardiogenic shock, and fatal arrhytmia. An accurate, easy and cost-effective biomarker is needed to predict MACE and mortality in patients with myocard infarct. Hypoxic liver injury (HLI) is a potential biomarker using serum glutamic-oxaloacetic transaminase (SGOT) level as the parameter. This study is aimed to discover HLI’s role in predicting MACE in non ST elevation myocard infarct (NSTEMI). Methods. This study was designed as cross sectional to predict MACE and prospective cohort for survival analysis. Study population was all NSTEMI patients admitted to ICCU of Cipto Mangunkusumo Hospital and study sample were NSTEMI patients admitted to ICCU of Cipto Mangunkusumo Hospital that meets all criteria during 2006-2016. Cut-off level of SGOT for HLI to predict MACE and mortality was analyzed using ROC curve and AUC. Survival analysis was done using Kaplan Meier curve and the difference was tested with log-rank. Results. A total of 277 subjects were included in this study. Incidence of MACE in this study was 51.3% (acute heart failure 48.4%, fatal arrhytmia 6.5%, and cardiogenic shock 7.2%). The mortality rate was 6.13%. The median of SGOT level on all subject was 35 U/L, 40 (range 8-2062) U/L in subjects with MACE and 31 (range 6-1642) U/L in subjects without MACE (p = 0.003). Cut-off level for SGOT used to predict MACE was 101 U/L (sensitivity 21.8%; specificity 89.6%; POR 2.727 (CI 95% 1.306- 5.696), p = 0.006). In multivariate analysis, HLI was insignificantly related to MACE. Cut-off level for SGOT used to predict survival was 99 U/L (sensitivity 23.5%; specificity 83.8%; likelihood ratio +1.46). There were no significant difference of survival between groups with HLI level below and above the cut-off SGOT level. Conclusion. Hypoxic liver injury (HLI) cannot be used to predict MACE in NSTEMI patients unless combined with other variables. There is no significant difference of survival between subjects with or without HLI.
Composite Lymphoma: Hodgkin and Non-Hodgkin Lymphoma A Case Report Soetandyo, Noorwati; Rebecca, Ruth Vonky; Yunti, Maria; Reksodiputro, Arry Harryanto
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 3
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Composite lymphoma (CL) is a rare disease. Composite lymphoma is two or more different type of lymphoma that sequentially or simultaneously occur in one anatomical site. Making a diagnosis of CL is a challenge and there is still no guidelines about the treatment. This case report is about a 36 y.o female with CL, sequentially consisted of Hodgkin and non-Hodgkin lymphoma.
The Role of Clinical Sign and The Added Value of Procalcitonin in Determining The Existance of Infection in The Treated Diabetic Foot Ulcer Aswar, Andra; Yunir, Em; Karuniawati, Anis; Harimurti, Kuntjoro
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 2
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Determinant Factors and Added Value of Osteoprotegerin (OPG) to Detect Carotid Intima-Media Thickness (CIMT) in Type 2 Diabetes Mellitus Patient Tedjasaputra, Shirly Elisa; Yunir, Em; Wijaya, Ika Prasetya; Setiati, Siti
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 2
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Relationship between Serum Interferon Gamma Level with Sputum Positivity of Acid-Fast Bacillus in New Case Pulmonary Tuberculosis Takdir, Andi Khomeini; Arief, Erwin; Tabri, Nur Ahmad; Seweng, Arifin
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 2
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The Distinction in Level of Stress, Anxiety, and Depression between Efavirenz with Nevirapine Therapies (Study on HIV/AIDS-infected patients at VCT-CST clinic Dr.Kariadi Hospital Semarang) Muflihatunnaimah, Muflihatunnaimah; Fitrikasari, Alifiati; Sofro, Muchlis Achsan Udji
Jurnal Penyakit Dalam Indonesia Vol. 5, No. 2
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