Garuda - Garba Rujukan Digital

All

Journal of Pharmaceutical and Sciences.

jps
Website

Published by Universitas Tjut Nyak Dhien

ISSN : - EISSN : 26563088 DOI : https://doi.org/10.36490/journal-jps.com

Core Subject : Health, Science, Agriculture, Engineering,

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 68 Documents

1 2 3 4 5

Search results for , issue "JPS Volume 6 Nomor 2 (2023)" : 68 Documents clear

Molecular Docking Senyawa Yang Berpotensi Sebagai Antikanker Payudara: Literature Review Anisa Fauziah; Adelia Fatharani; Cindhy Maulida Nurawaliah; Faizal Auladi Rivianto; Irene Virda Sakina; Marsah Rahmawati; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Cancer is a degenerative disease that has claimed many victims. Currently breast cancer is the second most common cancer that causes death after lung cancer and is the most common cancer suffered by women. Treatment of breast cancer is generally done with chemotherapy, radiotherapy, hormone therapy and surgery. Several synthetic drugs have been used to inhibit the growth of cancer cells. However, these drugs have dangerous side effects for the body so other alternatives are needed, including developing drugs derived from plants. To predict the activity of compounds from plants that have potential as anti-breast cancer, the molecular docking method was used. This review aims to inform compounds that have the potential as anti-breast cancer based on the results of molecular docking. The research method used was a literature study of 15 journals searched on the Google Scholar and Google databases related to molecular docking of breast anticancer compounds. The results of the review show that several compounds have the potential to inhibit breast cancer receptors including mangiferin compounds which are the best at inhibiting HER-2 receptors, quercetin glycoside compounds which are the best at inhibiting Bcl-2 receptors, quinine compounds which are the best at inhibiting ER-α receptors, compounds 6,7 -dihydro-17-hydroxyerisotrin is the best at inhibiting EGFR receptors, curcumin compounds are the best at inhibiting COX-2 receptors and eugenol compounds are the best at inhibiting ER-β receptors.

Kajian Interaksi Obat Pada Peresepan Pasien Diabetes Melitus Di Salah Satu Rumah Sakit Di Kota Bandung Ameilia Ameilia; Sri Adi Sumiwi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Introduction: Drug interactions are events that occur if the use of drugs in a shared time. The drug interactions that occur can produce adverse or beneficial effects. Purpose: to determine the potential interaction of drugs given to outpatients with diabetes mellitus diagnosis in one of the hospitals. Method: the study was conducted using a descriptive analysis design, by collecting retrospective data using prescription documents for diabetic patients in outpatient pharmacy installations in hospitals in the city of Bandung. Results: the study showed that the Biguanida group was often used as much as 82.4% and the interaction of the use of Glimepirid with metformin as many as 25 cases (21.2%) with a moderate level of interaction. Conclusion: The antidiabetic drug that is often used is the Biguanida group with a frequent interaction is Glimepirid with metformin.

Pengaruh Pemberian Obat Antidepresan terhadap Risiko Bunuh Diri: Literatur Review Febi Febriani Hasanah; Indah Laily Hilmi; Salman Salman
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Depression is a mental health disorder that often occurs to anyone regardless of age. Treatment of depression can be done with psychotherapy, administration of antidepressants, or a combination of both. However, the use of antidepressants is believed to increase the risk of suicidal behavior and ideation, especially in adolescent patients. The purpose of this study was to determine the effect of antidepressant therapy on the risk of suicide in adolescents. This research was conducted using the Literature Review method using the Google Scholar database. Articles obtained from the search process were then re-selected based on inclusion and exclusion criteria, so that 5 articles that match the criteria were obtained. The results of the study show that giving antidepressant drugs to patients can increase or decrease the risk of suicide in patients. Patients aged <18 years (children and adolescents) are considered to have a greater risk of suicide compared to adult and geriatric patients. Based on these results, it can be concluded that the use of antidepressant drugs must be done wisely. Patients need to receive supervision and support from the closest people in using antidepressant drugs to avoid the risk of suicide in patients.

Metode Analisis Natrium Benzoat pada Makanan dan Minuman: Literatur Review Erlangga Muhamad Prayuda; Febi Febriani Hasanah; Rika Valensia; Nurma Dwi Rahmawati; Marsah Rahmawati Utami
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Preservatives are food additives that can inhibit the growth of microorganisms so that food does not get stale easily. Sodium benzoate is one of the preservatives that is allowed to be used in food but within a predetermined limit of <1 g / kg according to BPOM RI. The purpose of this review is to find out an overview and provide information about the method of analyzing sodium benzoate levels in food and comparing the results with the provisions. The method used is literature review from various journals with a span of 10 years. The results of this study, the method of analyzing sodium benzoate in food can be carried out qualitatively and quantitatively. Qualitative tests can use the addition of FeCl3, test kits, and KLT, while quantitative tests can use KCKT, spectrophotometry UV-Vis and titration. The samples studied from 11 journals obtained were syrup, sauce (tomato and chili), soy sauce, beverage and strawberry jam products produced industrially and/or home-produced. The conclusion of the various methods tested is that there are still many food producers who use sodium benzoate as a preservative, but not all samples studied are in accordance with the provisions

Tingkat Pengetahuan Penggunaan Antibiotik Terhadap Resistensi Antolin Lamsar Rogabe Samosir; Indah Laily Hilmi; Salman Salman
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Antibiotics are drugs used to treat bacterial acaic infections. Unreasonable use of antibiotics will cause resistance to a bacterium. I did a review of this journal aimed at analyzing the level of knowledge of antibiotic use in the community to prevent the occurrence or increase of cases of resistance to a bacterium. For the results obtained from the results of journal reviews, the level of knowledge of the average antibiotic use is still relatively up and down.

Review Artikel: Docking Molekuler Obat Anti Diabetes Melitus Issabella Elsiana; Kholifatul Ulum; Klaritya Anisya Kurnia; Shafa Qotrunnada Widyatamaka; Shipa Paujiah
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Diabetes mellitus is a disease caused by damage to the pancreas organ such as insulin secretion abnormalities, insulin resistance, and insufficient production of the hormone insulin which can cause an increase in blood glucose levels. To overcome this, people with diabetes mellitus need antidiabetic drugs. In general, these drugs work by controlling sugar levels in the body. Although there are various therapeutic options for treating diabetes mellitus, there are often side effects that can be detrimental. Therefore there is a need for effective treatment, and the use of natural products is recommended as an alternative treatment method. This study aims to find natural product compounds that have medicinal potential as an alternative treatment for diabetes mellitus. The method used in this review is by searching published scientific literature in the form of PubMed, Elsevier journals, NCBI, and Google Scholar by differentiating the exclusions that have been set. The results of this review show positive results where there are various natural compound compounds that have potential as antidiabetic drugs. However, this is still limited to molecular docking, so further studies are needed.

Review Artikel: Pemanfaatan Kimia Komputasi Dengan Berbagai Metode Dalam Menentukan Desain Senyawa Baru Lina Nurfadhila; Diah Muldianah; Diany Aprillia Nurdimayanthi; Dinda Shafira Rahmawati; Hajar Hartati; Hana Fadhilah
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Research in the pharmaceutical field is helped by the development of technology and science, one of which is in the field of medicinal chemistry related to drug discovery and treatment development design. Computation is one of the techniques in drug development with molecular docking and Quantitative Structure Activity (HKSA) methods which include synthesis, purification, design, identification and activity testing of a compound. The method used is to conduct studies from various sources with a total of 29 journals found on various official websites and which are used as the main journal as many as 10 journals with various computational techniques, namely molecular docking, PM3 semiempirical, AM1 semiempirical, in silico and HKSA. The potential of compounds from various literatures results in several medicinal purposes, namely as anticancer, antimalarial, antibacterial, anti-HIV and covid prevention. The potential of these compounds is obtained from different chemical compounds. The compounds used in this journal include compounds derived from 1,3-dibenzolythiourea, quinine compounds, fluoroquinolone parent compounds, chalcone-derived compounds, kuwanon compounds and their derivatives, leonurin compounds and their derivatives, compounds derived from N-(Benzoil)-N'-phenylthiourea, Beta asaron-derived compounds, meisiindigo-derived compounds and quercetin compounds.

Review Article : Implikasi Suplemen Asam Folat Prenatal terhadap Risiko Autism Spectrum Disorder (ASD) pada Keturunannya Diah Muldianah; Indah Laily Hilmi; Salman Salman
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Folic acid plays an important role for the health of mothers and babies, especially in the growth and development of the fetus. Based on several previous studies, it was found that prenatal folic acid deficiency or excess can increase the risk of Autism Spectrum Disease (ASD) in infants. This raises concerns about the adverse effects of prenatal folic acid supplements including an increased risk of ASD. Therefore, this literature review article was created to further explore the implications or involvement of maternal folic acid supplementation on the risk of ASD in their offspring. The Google Scholar, Pubmed, and Connected Papers electronic databases were used to find literature that met the criteria. The results of this review found a potential beneficial effect of prenatal folic acid supplementation on the risk of developing ASD, although conflicting results have been reported. In summary, this literature review article demonstrates that prenatal folic acid supplementation can significantly reduce the risk of ASD in offspring compared to women without prenatal folic acid supplementation.

Metode Analisis Cemaran Mikroba pada Makanan : Review Artikel Aditia Putra Tama; Vina Luthfiana Hasna; Khamairah Azzahrawaani Hermawan; Marsah Rahmawati Utami; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Food is one of the important things in the sustainability of human life. The main function of food for humans is to meet the nutritional needs of the body, where these nutrients must be met according to gender, age, daily physical activity, and body weight. As the main and basic function of food itself, in order to be a good source of nutrients and energy, of course, the food must be ensured to be safe, clean, does not contain harmful food-enhancing ingredients, and is free from sources of disease. The source of this disease can arise from food that has been contaminated, one of which is food contaminated with microbial contamination. This article aims to inform the analysis of microbial contamination methods in various foods. The method used in writing this article review is to search for several references in the form of scientific journals or scientific articles from research with the keyword microbial contamination analysis.

Formulasi Sediaan Ekstrak Etanol Kulit Buah Alpukat (Persea Americana Mill.) Sebagai Krim Alas Bedak Hamdhani Hamdhani; Muharni Saputri; Sudewi Sudewi; Linda Margata
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Background; Avocado (Persea americana Mill.) is a plant that is widely grown in Indonesia. Peel avocado is known to contain secondary metabolites such as flavonoids which are useful as antioxidants. This study aims to determine the peel of avocado (Persea americana Mill.) in the form of ethanol extract can be formulated into a foundation cream preparation which at a certain concentration has antioxidant activity. Method; The study was conducted using an experimental method, using peel avocado test material (Persea americana Mill.) processed by maceration using 96% ethanol extract formulated into a foundation cream preparation in a concentration of 1.5%; 2%; 2.5%; and blank. Examination of the physical quality of the preparation includes homogeneity test, pH test, viscosity test, stability test, irritation test, moisture test and antioxidant activity test. Result; The results showed that the yield of peel avocado (Persea americana Mill.) was 12.99%. All formulations met the requirements of the gel evaluation test with a pH range of 6.0-6.5. After doing the cycling test, it was 5.9-6.2. The viscosity results are 15,250-20,050 mPa.S. All formulations are homogeneous and stable. Formulation 3 has an IC50 value of (54.74µg/mL) in the "strong" antioxidant category and has a % recovery value of 67.23%.

Page 1 of 7 | Total Record : 68

1 2 3 4 5

Filter by Year

2023 2023

Filter By Issues

All Issue JPS Volume 9 Nomor 1 (2026) JPS Volume 8 Nomor 4 (2025) JPS Volume 8 Nomor 3 (2025) JPS Volume 8 Nomor 2 (2025) JPS Volume 8 Nomor 1 (2025) JPS Volume 7 Nomor 4 (2024) JPS Volume 7 Nomor 3 (2024) JPS Volume 7 Nomor 2 (2024) JPS Volume 7 Nomor 1 (2024) JPS Volume 6 Nomor 4 (2023) JPS Volume 6 Nomor 3 (2023) JPS Volume 6 Nomor 2 (2023) JPS Volume 6 Nomor 1 (2023) Suppl. 1, No. 1 (2023) JPS Volume 1 Nomor 1 (2018) More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Salman

Contact Email
salman.kimia@gmail.com

Phone
+6285277011177

Journal Mail Official
admin@journal-jps.com

Editorial Address
Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location
Kota medan,

Sumatera utara

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Salman

Contact Email salman.kimia@gmail.com

Phone +6285277011177

Journal Mail Official admin@journal-jps.com

Editorial Address Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location Kota medan, Sumatera utara INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Salman

Contact Email
salman.kimia@gmail.com

Phone
+6285277011177

Journal Mail Official
admin@journal-jps.com

Editorial Address
Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location
Kota medan,

Sumatera utara

INDONESIA