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Rizky Akbar
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INDONESIA
IJRETINA - International Journal of Retina
Published by Indonesian Vitreoretinal Society
ISSN : 26148684     EISSN : 26148536     DOI : https://doi.org/10.35479/ijretina.2023.vol006.iss0
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
International Journal of Retina is an open access journal, accepting article in English language from all over the worlds. The aims is to provide international researchers, doctors, and clinicians in the basic and clinical fields of ophthalmology, especially retina to publish the original article, case reports, or systematic review.
Arjuna Subject : Kedokteran - Ophthalmology
Articles 148 Documents
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Clinical Characteristics and Management of Wet Age-Related Macular Degeneration at Cipto Mangunkusumo Hospital Kirana, Jakarta, Indonesia Leonedine, Tengku Viona Zohra; Victor, Andi Arus; Djatikusumo, Ari; Adriono, Gitalisa Andayani; Yudanta, Anggun Rama; Hutapea, Mario Marbungaran; Suryoadji, Kemal Akbar
International Journal of Retina Vol 7 No 2 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss002.291

Abstract

Introduction: Age-related macular degeneration (AMD) is a leading cause of blindness globally, with wet AMD being particularly debilitating. The prevalence of AMD is increasing, necessitating a deeper understanding of its clinical characteristics and management. This study aims to investigate the demographic and clinical features, management, and treatment outcomes of wet AMD at Cipto Mangunkusumo Hospital during January-December 2022. Methods: A retrospective descriptive study was conducted, analyzing medical records of wet AMD patients treated during the specified period. Data analysis included patient demographics, clinical characteristics, treatment modalities, and outcomes. Results: Of 129 eyes from 122 patients, 115 eyes met the inclusion criteria. The majority were female (55.7%) with an average age of 67 years. Most patients presented with blurry vision (93.9%) and received Patizra anti-VEGF injections (60.9%). Hypertension was the most common risk factor (28.7%). Anti-VEGF treatment significantly reduced central macular thickness (p < 0.05) but had no significant impact on visual acuity. Avastin and Patizra injections similarly influenced macular thickness but not visual acuity. There were no significant differences between loading and non-loading dose groups in terms of outcomes. Conclusion: Anti-VEGF treatment effectively reduces central macular thickness in wet AMD patients, regardless of the specific agent used. However, it does not significantly improve visual acuity. Further research is needed to explore differences between loading and non-loading dose protocols, compare treatment strategies, and investigate demographic risk factors. Consistency in visual acuity documentation using the ETDRS format is recommended for future studies.
Resolution of Traumatic Retinal Detachment with Intravitreal Bevacizumab: a case report Paris, Jai; Macri, Carmelo; Chan, Weng Onn
International Journal of Retina Vol 7 No 1 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss001.274

Abstract

Introduction: Traumatic retinal detachment (RD) without an observable break following ocular trauma is rare. Case Report: A 14-year-old male who suffered from traumatic RD following an explosive injury. Initial examination revealed iridodialysis, vitreous haemorrhage, and impaired visual acuity in the right eye. One week later, the patient developed a macula-off retinal detachment secondary to subretinal exudation without an identifiable retinal break, and a decision was made to trial intravitreal injection (IVI) of bevacizumab before considering surgical intervention. Two days after IVI, significant improvements in subretinal fluid (SRF) were observed, and the retina remained attached during follow-up. The patient's visual acuity and anatomical outcomes improved, and no choroidal neovascularization (CNV) was detected at the 7-month follow-up. Discussion: A rare instance of traumatic RD associated with choroidal rupture, and without an observable retinal break. While the majority of post-traumatic RD is due to pathological breaks, our case highlights the possibility of detachment secondary to exudation resulting from extensive haemorrhage and choroidal ruptura. Conclusion: This case demonstrates the potential efficacy of anti-VEGF therapy in traumatic RD secondary to significant subretinal exudation and offers a less invasive treatment option for select cases, warranting further investigation and long-term studies for a larger patient cohort.
Clinical Characteristics of Patients with Retinal Vein Occlusion and Macular Edema at Cipto Mangunkusumo Hospital Kirana in Indonesia Isfyanto, Isfyanto; Djatikusumo, Ari; Andayani, Gitalisa; Yudantha, Anggun Rama; Hutapea, Mario Marbungaran; Suryoadji, Kemal Akbar; Victor, Andi Arus
International Journal of Retina Vol 7 No 1 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss001.271

Abstract

Introduction: Retinal vein occlusion (RVO) is a significant retinal vascular disease, often resulting in macular edema and vision impairment. This study aims to investigate the clinical characteristics, management, and outcomes of RVO patients with macular edema at Cipto Mangunkusumo Hospital Kirana from January 2020 to December 2021. Methods: This retrospective descriptive study analyzed medical records of 85 RVO patients with macular edema. Demographic data, clinical characteristics, management approaches, and treatment outcomes were examined. Data were analyzed using SPSS. Results: Most patients were over 50 years old, predominantly male, and affected in one eye. Hypertension and diabetes mellitus were common comorbidities. Central RVO cases had worse initial visual acuity and macular thickness than branch RVO cases. Anti-VEGF injections were the primary therapy, and patients received an average of two injections in the first year. Macular thickness reduced after anti-VEGF injections, but visual acuity improvement was minimal. Conclusion: Patients with RVO and macular edema are often older males with systemic risk factors. Anti-VEGF injections are the primary treatment, with improvements in macular thickness but limited visual acuity gain. Patient education, comprehensive management, and public awareness are recommended to enhance RVO care. Further research to analyze parameter relationships is needed.
GUIDELINES FOR THE DIAGNOSIS AND MANAGEMENT OF DIABETIC RETINOPATHY AND DIABETIC MACULAR EDEMA IN INDONESIA Harley, Ohisa; Hertanto, Martin; Sembiring, Sindy Boru; Yustiarini, Ima; Susilo, Teguh; Dharma, Andhika Guna; Sjahreza, Emil; Firmansyah, M; Iskandar, Erwin; Agustiawan, Referano; Andayani, Ari; Dewi, Nadia Artha; Andayani, Gitalisa; Djatikusumo, Ari; Elvioza, Elvioza; Ichsan, Andi M; Kartasasmita, Arief S
International Journal of Retina Vol 7 No 2 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss002.300

Abstract

Diabetic retinopathy (DR) and diabetic macular edema (DME) are among the microvascular complications in individuals with diabetes mellitus (DM) that can lead to blindness if not diagnosed early and managed appropriately. Both disorders can be diagnosed and treated using a variety of techniques. Treatment modalities include laser photocoagulation therapy, vitrectomy surgery, intraocular steroid injections, and anti-vascular endothelial growth factor (anti-VEGF) injections. These methods can help avoid blindness when used in conjunction with metabolic control. These recommendations were created with the use of evidence-based medicine principles to help medical professionals—particularly ophthalmologists—identify and treat cases of DR and DME.The primary objective is to provide consensus recommendations and hopefully reduce the incidence of blindness caused by DR and DME in Indonesia.
PHOTOFUNDUS CHARACTERISTIC OF DIABETES MELITUS PATIENT IN PRIMARY AND SECONDARY HEALTH CARE CENTERS Winly, Winly; Ari Suryathi, Ni Made; Suryanadi, Ni Made; Andayani, Ari; Manuaba, Ida Bagus Putra
International Journal of Retina Vol 7 No 2 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss002.292

Abstract

Introduction: The prevalence of diabetes mellitus increases over time in line with the prevalence of diabetic retinopathy is also expected to increase. It is not possible to determine which diabetic patients will have retinopathy, so therefore screening is needed. This study aims to have a better understanding in managing DM patients in the future, especially in cases of diabetic retinopathy in primary, secondary & community health care centers. Methods: A descriptive analytical study. Data collected cross sectional study based of characteristic and portable photo fundus from DM patients while doing social service at a health service center. Results: Portable photo fundus in this study, screening 138 DM patients, with majority of subjects is in the range 44-64 year age group (68.1%). There was the same number of patient between gender or type. History of DM in the family (63.0%) with a duration of DM ≤ 5 years (56.5%), mostly the quality of photo fundus that can be assessed (97.1%), patients who needed further treatment were referred to the ophthalmologist 59 cases (42.8%). Conclusion: People who live far from cities and have limited access to health facilities can be reached using this portable photo fundus, so that blindness in peripheral areas will be more easily detected and this can be used as a screening modality and blindness due to diabetic retinopathy can be prevented.
DIAGNOSTIC AND THERAPEUTIC CHALLENGES OF POSTERIOR SCLERITIS MIMICKING CHOROIDAL MELANOMA yuniasih, kristina; Dewi, Nadia Artha; Sofia, Ovi
International Journal of Retina Vol 7 No 1 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss001.256

Abstract

EVALUATION OF ENDOTHELIN-1 AND GLYCATED HAEMOGLOBIN IN TYPE 2 DIABETIC PATIENTS WITH AND WITHOUT RETINOPATHY DOMNGANG, Christelle; DEFFO, Alex; EYOMBO, Stephanie; YOUTE, O’Neal; TEDONG, Leonard; KAGMENI, Giles; SOBNGWI, Eugene
International Journal of Retina Vol 7 No 1 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss001.255

Abstract

Introduction: Diabetic retinopathy (DR) can lead to blindness and therefore requires early diagnosis and careful monitoring. Method: The present cross-sectional analytical survey assessed endothelin-1 (ET-1) and glycated haemoglobin (HbA1C) levels, two DR markers, in type 2 diabetic patients with and without DR in the National Obesity Centre of the Yaoundé Central Hospital in Cameroon, from February 1 to July 31, 2021. It was carried out on DR and non-DR patients, and non-diabetic patients. Various clinical parameters related to diabetes were collected, and a comprehensive ophthalmological examination as well as an analysis of HbA1C and ET-1 in participants’ blood samples were performed. Results: A total of 12 DR participants, 32 non-diabetic participants, and 45 diabetic participants without DR were enrolled. The majority of diabetic patients did not have a good HbA1C level, without a statistical difference (p-value = 0.702) between DR (75%) and non-DR (80%) patients. For ET-1, it was recorded high serum levels in diabetic patients (10.9 pg/mL [10.00 – 19.50]) compared (p-value = 0.04) to non-diabetic patients (10.6 pg/mL [6.3 – 13.5]). Moreover, DR patients recorded serum levels of ET-1 greater than (p=0.03) non-DR patients (13.1 pg/mL [10.89-21.42] vs 10.8 pg/mL [10.00-18.9]). Conclusion: These biomarker levels are a warning in DR evolution of diabetic patients. ET-1 could be a better control biomarker than HbA1c in the clinician management of DR according to this study. Thus, it is necessary to improve the description of these biomarkers in order to reinforce their use.
Retinal vasculature by optical coherence tomography angiography after YAG laser capsulotomy in non diabetic patients Abokahla, Osama Abdelgalil; Ghoneim, Ehab Mahmoud; Mohamed, Mohamed Mounir
International Journal of Retina Vol 7 No 2 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss002.296

Abstract

Introduction: This study aimed to evaluate the effect of Neodymium-doped Yttrium Aluminum-Garnet (Nd: YAG) laser capsulotomy on retinal vessel perfusion densities and macular thickness using optical coherence tomography angiography (OCT-A). Methods: The study included 35 eyes of 35 participants with an average age of 70 years old. The participants having posterior capsule opacification were non-diabetic. The preoperative evaluation included history taking, ophthalmological examination and OCT-A was done. All patients underwent YAG laser posterior capsulotomy and then macular thickness and retinal microvascular changes were assessed at one month using OCT-A. Results: There was significant improvement of Best Corrected Visual Acuity (BCVA) (Decimal) post laser capsulotomy (P< 0.001), No significant change was determined before and after capsulotomy in macular thickness measurements, and Perfusion density in parafovea and perifovea layers. (All p > 0.05). Conclusion: Nd-YAG laser capsulotomy for posterior capsule opacification is considered to be a safe procedure and has no visible effect on macular thickness measurements, flow areas, and vessel perfusion densities.
The Association Between Vitreous Vascular Endothelial Growth Factor Levels with Visual Acuity Before and After Pars Plana Vitrectomy in Proliferative Diabetic Retinopathy Noviantari, I Gusti Agung Ratna; Suryathi, Ni Made Ari; Triningrat, A.A. Mas Putrawati; Widiana, I Gde Raka; Andayani, Ari; Jayanegara, I Wayan Gede; Pantjawati, Ni Luh Diah
International Journal of Retina Vol 7 No 2 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss002.257

Abstract

Introduction: Vascular endothelial growth factor (VEGF) plays a crucial role in the development of proliferative diabetic retinopathy. Elevated levels of VEGF in the vitreous have been found to be associated with the severity of ischemia and neovascularization, which can lead to a decline in visual acuity. This study aims to determine the association between vitreous VEGF levels and improvement in visual acuity before and after PPV in PDR patients. Methods: This research is an analytic observational study with a pre-post single group design. The subjects of this study were all PDR patients who received PPV therapy at three hospital in Bali Province, Indonesia. Consecutive sampling method were conducted. The independent variable is vitreous VEGF, whilst pre and post-PPV visual acuity is the outcomes. We performed mean comparison and multivariable statistical test using IBM SPSS version 25. Result: 45 people were included in this study. Improvement in visual acuity after PPV compared to before PPV with an average improvement of 0.54 logMAR (p=0.001). Based on the ANCOVA multivariate analysis, factors affecting visual acuity improvement after PPV were preoperative vision (p<0.001), postoperative vision (p<0.001), HbA1c level (p=0.036), and DM duration (p=0.024). There was no association between high vitreous VEGF levels and visual acuity improvement (PR=0.95; 95% CI=0.55-1.63;p=0.841). Conclusion: This study concluded that there is an association between PPV and visual acuity improvement. However, clinicians should be aware of several confounding factors that affect visual acuity improvement, including pre-PPV visual acuity, post-PPV visual acuity, duration of DM, and HbA1c level. There is no relationship between vitreous VEGF and visual acuity before and after PPV in PDR, but it is necessary to keep good records of lens status and intraocular pressure status. Further research is needed and the research time is extended to evaluate a better visual outcome.
COMBINED IMMEDIATE PARS PLANA VITRECTOMY AND PHACOEMULSIFICATION AS AN EFFECTIVE TREATMENT ON MACULA-OFF RHEGMATOGENOUS RETINAL DETACHMENT Hendrawan, Kevin Anggakusuma; Andayani, Ari; Siska, Siska; Umbu Lapu, Ervan Suryanti; Yudistira, Yudistira
International Journal of Retina Vol 8 No 1 (2025): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2025.vol008.iss001.295

Abstract

Introduction: Macula-off rhegmatogenous retinal detachment (RRD) is a complicated condition which can caused poor visual prognosis if not treated properly. Recent studies have been proposed an early surgical treatment on this condition to get better anatomical and functional outcomes. Case Report: A 55-year-old male patient presented with history of blurred vision in left eye of 18 hours duration. Patient had history of seeing flashing light and black dots prior to the symptoms. On evaluation there was a macula-off RRD with immature senile cataract. Immediate phacoemulsification followed by pars plana vitrectomy was done. Good visual recovery with best corrected visual acuity 0.00 logMAR was obtained 3 months after the initial surgery. Discussion: In patient with macula-off RRD, delaying the surgical treatment could possibly worsen the visual prognosis. Accurate diagnosis with timely surgical intervention give a good visual outcome by allowing faster rearrangement of macula anatomy. Conclusion: Early surgical intervention is required to provide better visual outcome on macula-off RRD. In the presents of cataract, combined phacoemulsification with PPV as the main intervention may be considered an appropriate approach. The development of ERM is one of the difficulties that RRD patients face, and it needs to be carefully evaluated to avoid the need for additional surgery.

Page 13 of 15 | Total Record : 148

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