cover
Contact Name
Muhammad Iqhrammullah
Contact Email
m.iqhram@narraj.org
Phone
+62895600103052
Journal Mail Official
m.iqhram@narraj.org
Editorial Address
Jl. T. Tanoeh Abee, Durussalam, 23111, Banda Aceh
Location
Kota banda aceh,
Aceh
INDONESIA
Narra X
ISSN : -     EISSN : 29882990     DOI : DOI: https://doi.org/10.52225/narrax
Core Subject : Health, Science,
Narra X is a multidisciplinary journal, published three times in a year (April, August, and December). The journal aims to act as a platform for rapid scientific communication while upholding the highest integrity. Articles are published in a form of Original articles, Short Report, Case Reports, Methods articles, Review articles, and Letters to the Editor. All submitted articles are subjected to peer-review prior to their publication. As a multidisciplinary journal, Narra X welcomes articles from any subject field, depending on the editorial capacity. At the moment, Narra X is handled by section editors in the following fields: Health and medicine Chemistry Biology Mathematics Physics Narra X is online only journal and all articles do not have page numbers; instead, they are given a unique article number.
Arjuna Subject : -
Articles 7 Documents
Search results for , issue "Vol. 3 No. 2 (2025): August 2025" : 7 Documents clear
Factors associated with clinical outcomes among children with delayed diagnosis of critical congenital heart disease: A cross-sectional study Fachrozi, Muhammad R.; Adriansyah, Rizky; Pratita, Winra; Wahyuni, Arlinda S.; Tobing, Tina CL.; Trisnawati, Yunnie
Narra X Vol. 3 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v3i2.191

Abstract

Delayed detection of critical congenital heart disease (CHD) is associated with increased morbidity and mortality. Currently, there is a paucity of data on children with critical CHD in Indonesia. The aim of this study was to investigate the factors contributing to delayed diagnosis of critical CHD and its association with clinical outcomes such as mortality, heart failure, intensive care unit (ICU) admission, and ventilator use. A cross-sectional study was conducted using medical records from Haji Adam Malik Medan General Hospital. The study included all children aged 0 to 18 years diagnosed with critical CHD. The statistical analysis was performed by utilizing SPSS version 25.0. A total of 59 subjects were analyzed. The findings revealed a significant relationship between factors such as age, sex, respiratory tract infections, type of CHD, surgical interventions, and underlying syndromic abnormalities with various clinical outcomes. Delayed diagnosis of critical CHD was associated with increased mortality, heart failure, ICU admission, and ventilator use, with these outcomes influenced by the aforementioned factors.
Gender disparities in HIV infections: A narrative review of the persistent vulnerability of adolescent girls in Sub-Saharan Africa Musa, Shuaibu S.; Othman, Zhinya K.; Fadele, Kehinde P.; Ahmed, Mohamed M.; Okesanya, Olalekan J.; Ibrahim, Adamu M.; Ishak, Abubakar S.; Alhassan, Muhammad Y.; Oyinloye, Emmanuel A.; Ogunleke, Praise O.; Alaka, Hassan O.; Jibo, Abdulrahman G.; Paz, Pearl IVD.; Lucero-Prisno III, Don E.
Narra X Vol. 3 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v3i2.211

Abstract

The human immunodeficiency virus (HIV) epidemic in Sub-Saharan Africa (SSA) disproportionately affects adolescent girls and young women (AGYW), who face a risk of infection up to three times higher than their male peers. SSA accounts for 65% of the global HIV burden, with Eastern and Southern Africa showing particularly high rates. The aim of this study was to examine the persistent gender disparities in HIV infections, focusing on the biological, social, and structural drivers of AGYW’s heightened vulnerability. Biological factors such as immature cervical development and hormonal influences intersect with social determinants, including gender inequality, cultural norms, and economic pressures. These factors reduce young women’s ability to negotiate safer sexual practices and increase reliance on transactional relationships with older partners. Despite initiatives such as determined, resilient, empowered, AIDS-free, mentored, and safe (DREAMS) and Education Plus, barriers such as stigma, gender-based violence, and limited access to youth-friendly sexual and reproductive health services persist. Addressing these disparities requires multi-level, gender-responsive interventions that strengthen healthcare access, expand female-controlled prevention options, and promote education and economic empowerment. Closing the gender gap in HIV outcomes will demand sustained policy commitment and community engagement tailored to the needs of adolescent girls in SSA.
A scoping review of potential biomaterials as optimal platforms for triboelectric nanogenerators Saputra, Kormil; Khuzaima, Nabila D.; Melani, Melani; Wahyudin, Wahyudin; Madani, Awanda OP.
Narra X Vol. 3 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v3i2.214

Abstract

The increasing human reliance on electricity, driven by rapid technological advancement, continues to depend largely on non-renewable fossil fuels, raising critical concerns about energy sustainability and environmental degradation. This study aims to explore the potential of biomaterials as alternative platforms for enhancing the performance of Triboelectric Nanogenerators (TENGs), using a scoping review approach. A systematic literature review was conducted utilizing the Scopus, Crossref, and Google Scholar databases, guided by the PRISMA Extension for Scoping Reviews (PRISMA-ScR) framework. Relevant studies were analyzed based on publication trends, types of biomaterials employed, synthesis methods, operational mechanisms, and key electrical output parameters. The findings indicate that biomaterials such as cellulose, chitosan, and natural proteins exhibit promising triboelectric properties, contributing to improvements in energy conversion efficiency, biocompatibility, and operational stability of TENGs. Further research is recommended to optimize material structures and surface modifications to enhance charge transfer mechanisms. Additionally, the incorporation of carbon-based materials such as graphene and MXene with biomaterials has demonstrated significant potential to amplify device performance. This review also underscores the wide-ranging applications of biomaterial-based TENGs in wearable electronics, biomedical sensing, and eco-friendly energy systems. Overall, this study provides a comprehensive overview and valuable insights into the strategic role of biomaterials in advancing next-generation green energy technologies.
Effects of vitamin D supplementation on salivary cortisol and psychological health among postmenopausal women: A pilot quasi-experimental study Syahdema, Muhammad F.; Siregar, Muhammad FG.; Nasution, Hiro HD.; Prabudi, Muhammad O.; Marpaung, Johny; Sukatendel, Khairani
Narra X Vol. 3 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v3i2.224

Abstract

Menopause is a significant life transition often accompanied by mood disturbances, many of which are linked to cortisol levels and hypothalamic–pituitary–adrenal (HPA) axis dysregulation. Vitamin D deficiency is highly prevalent in postmenopausal women and shares overlapping adverse outcomes with menopausal symptoms. This study aimed to investigate the effect of vitamin D supplementation on salivary cortisol levels and psychological symptoms in postmenopausal women. This pilot study employed a quasi-experimental design, recruiting 32 postmenopausal women via consecutive sampling from the study population in Kwala Bekala Village, Medan Johor District. Participants were consecutively added into two groups, receiving either 1000 IU or 2000 IU of vitamin D daily for one month. Salivary cortisol levels and Depression, Anxiety, and Stress Scale (DASS) scores were measured before and after the intervention.  The findings revealed that serum 25(OH)D levels increased significantly in both groups, with higher post-supplementation levels in the 2000 IU group than in the 1000 IU group (28.94±5.86 ng/mL vs 24.13±5.28 ng/mL, p=0.021). Salivary cortisol decreased in both groups, with a greater reduction observed in the 2000 IU group (median Δ=9.55 ng/mL vs mean Δ=4.92±4.29 ng/mL, p=0.032). Psychological symptoms measured by DASS scores also improved significantly, with the 2000 IU group showing a larger reduction (mean Δ=11.31±6.65 vs median Δ=3.5, p=0.022). Vitamin D supplementation at both 1000 IU and 2000 IU effectively reduced salivary cortisol and improved psychological symptoms in postmenopausal women. Due to differences in baseline characteristics, caution is warranted when inferring clear dose superiority.
Leveraging technology and partnerships to strengthen post-market surveillance of substandard medicines in Nigeria Umar, Abbas B.; Okunola, Olayinka F.; Sani , Saifuddeen K.; Yahaya , Hafsat; Awotimiro , Oluwafemi; Sokunbi, Taiwo O.
Narra X Vol. 3 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v3i2.226

Abstract

The circulation of substandard and falsified (SF) medical products remains a persistent global health crisis, with a disproportionately severe impact on low- and middle-income countries (LMICs). Nigeria, as a major pharmaceutical market in Africa, is especially vulnerable due to a complex interplay of systemic challenges that weaken its regulatory framework. This review explores Nigeria's Post-Market Surveillance (PMS) landscape, highlighting key obstacles and leveraging recent advancements in technology and policy to propose an innovative, future-oriented strategy. Despite significant hurdles, the country has important opportunities to improve its PMS system through the strategic adoption of mobile authentication services, blockchain traceability, and artificial intelligence, along with targeted reforms. The paper concludes with specific, actionable policy recommendations, offering a roadmap for policymakers to develop a resilient, technology-driven PMS framework that safeguards public health and rebuilds trust in the nation's pharmaceutical supply chain.
Prevalence of cardiac arrhythmias in a hospital-based cohort of police officers in Guayaquil Silva-Rojas, Glen A.; Farfán-Cano, Galo G.; Silva-Rojas, Kevin J.; Zea, Ariana
Narra X Vol. 3 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v3i2.227

Abstract

Cardiac arrhythmias are a relevant cause of morbidity worldwide and are influenced by modifiable cardiovascular risk factors and occupational stress. Police officers face unique psychological and physical stressors, yet data on arrhythmias in this group remain scarce in Latin America. The aim of this study was to review medical records of police officers treated at the National Police Hospital of Guayaquil from January 2017 to December 2022. From 3,334 cardiology consultations, 100 officers with confirmed arrhythmias were identified. Demographic, clinical, and diagnostic data were analyzed using descriptive statistics, non-parametric correlations, and multivariate logistic regression. The proportion of arrhythmias among police officers attending cardiology care was 29.9% (95% confidence interval (CI): 24.8–35.0%), corresponding to 3.0% of all cardiology consultations. Supraventricular tachycardia was the most frequent subtype (27%), followed by atrial fibrillation/flutter (11%). No significant associations were found between arrhythmia type and age, sex, or service status (all p>0.36). Logistic regression identified hypertension (OR: 2.3; 95%CI: 1.7–3.1), obesity (OR: 1.8; 95%CI: 1.3–2.5), and occupational stress documented in medical records (OR: 1.6; 95%CI: 1.2–2.1) as independent predictors. This exploratory hospital-based study describes the frequency and distribution of cardiac arrhythmias in Ecuadorian police officers and highlights their association with modifiable risk factors and occupational stress. Given the retrospective single-center design and selective sample, the results should not be generalized to the broader police population. Larger multicenter studies are required to better quantify arrhythmic burden in law enforcement personnel.
Phytochemical screening of bioactive compounds and antioxidant activity of methanol extract from Melia Azedarach L. fruit: Exploring for antidiabetic potential Aini, Qurratu; Nurdin, Nurdin; Mustanir, Mustanir; Safrida, Safrida; Fauzi, Tio R.
Narra X Vol. 3 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v3i2.229

Abstract

Melia azedarach L. (neem fruit) is a traditional plant with diverse bioactive constituents, yet its phytochemical profile and pharmacological potential remain underexplored. This study aimed to screen bioactive compounds and evaluate the antioxidant activity of methanol extract from M. azedarach fruit, while further performing computational exploration on its antidiabetic potential. M. azedarach fruits were macerated in methanol and analyzed through phytochemical screening, total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity (DPPH assay). GC-MS was used to identify chemical constituents. Molecular docking was performed using a blind docking approach in CBDock2 against five protein targets, which included DPP-4, PTPN1, α-amylase, NrfA, and AKR1B1. Protocol validation was ensured by successful re-docking of co-crystallized ligands (RMSD < 2.0 Å). The extract was observed to contain terpenoids, steroids, flavonoids, and phenolics, with high TPC (479.8 mg GAE/g) and TFC (52.7 mg QE/g). Antioxidant activity was moderate (IC50 = 102.27 µg/mL). GC-MS identified 14 compounds, including cucurbitacins, ursolic acid derivatives, α-amyrin, taraxasterol, and ergostane-type sterols. Docking revealed moderate affinities (–5.0 to –6.5 kcal·mol-1) for most compounds. The cucurbitacin bound α-amylase (–13.6 kcal·mol-1) and NrfA (–8.5 kcal·mol-1), and taraxasterol exhibited broad-spectrum activity across all targets (–7.1 to –9.2 kcal·mol-1). M. azedarach fruit demonstrates moderate antioxidant activity and contains diverse phytochemicals with multitarget interactions relevant to glucose regulation. Strong binding to DPP-4, PTPN1, α-amylase, and AKR1B1 suggests potential antidiabetic properties through inhibition of carbohydrate digestion, enhancement of insulin signaling, and prevention of diabetic complications.

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