cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Rivan Danuaji
Contact Email
magnaneurologica@mail.uns.ac.id
Phone
+6282138018361
Journal Mail Official
magnaneurologica@mail.uns.ac.id
Editorial Address
Departement of Neurology, Faculty of Medicine Universitas Sebelas Maret, Surakarta, Indonesia Jl. Kol. Sutarto No. 132 Surakarta, Indonesia
Location
Kota surakarta,
Jawa tengah
INDONESIA
Magna Neurologica
Published by Universitas Sebelas Maret
ISSN : 29636027     EISSN : 29853729     DOI : https://doi.org/10.20961/magnaneurologica.v1i2.647
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health
Magna Neurologica is a peer-reviewed and open access journal that focuses on promoting neurological sciences generated from basic neurosciences and clinical neurology. This journal publishes original articles, reviews, and also interesting case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures of neurology disease, treatment, or other health issues related to neurology that is important also acceptable. Letters and commentaries of our published articles are welcomed.
Arjuna Subject : Kedokteran - Neurologi Klinis
Articles 52 Documents
 1   2   3   4   5 
The Effectiveness of Transcranial Magnetic Stimulation in Post Stroke Dysphagia: A Case Report Ginting, Suska Lara; Hambarsari, Yetty; Danuaji, Rivan; Hamidi, Baarid Luqman
Magna Neurologica Vol. 2 No. 1 (2024): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v2i1.942

Abstract

Background: A 72-year-old male, experiencing dysphagia and left-sided weakness for six months post-stroke, encountered challenges such as coughing and choking during the consumption of liquids and soft foods, along with a prolonged meal-swallowing process. Magnetic Resonance Imaging (MRI) revealed bilateral thrombotic infarction and left lateralization. Case: The Gugging Swallowing Screening Scale (GUSS) assessment demonstrated severe impairment with a total score of 7, persisting despite conventional physiotherapy attempts to improve swallowing function. Subsequently, repetitive transcranial magnetic stimulation (rTMS) was implemented, involving high-intensity stimulation in the ipsilesional hemisphere and low-intensity stimulation in the contralesional hemisphere. Remarkably, one-month post-rTMS, the patient displayed significant progress, evidenced by an improved GUSS score of 15, indicating enhanced swallowing function. Discussion: This case emphasizes the positive impact of bilateral rTMS hemispheric stimulation on post-stroke dysphagia. The strategic application of high-intensity ipsilesional and low-intensity contralesional stimulation emerged as an effective intervention for alleviating swallowing difficulties. Conclusion: These findings highlight the potential of rTMS as an innovative therapeutic approach for persistent dysphagia following a stroke. Repetitive transcranial magnetic stimulation (rTMS) has shown significant potential as an innovative and effective therapeutic approach for managing persistent post-stroke dysphagia. This case highlights the role of tailored rTMS protocols in improving swallowing function, with recovery influenced by factors such as stroke severity, dysphagia severity, age, nutritional status, timing of intervention, and lesion location.
The Features of Comorbidity of Stroke in The Indonesian Population: Findings from The Indonesian Family Life Survey (IFLS-5) Muvida; Amar, Filzah
Magna Neurologica Vol. 2 No. 2 (2024): July
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v2i2.948

Abstract

Background: Comorbidities are associated with a worse stroke prognosis and more challenging clinical management. However, population-based research related to stroke comorbidities in Indonesia is still limited. Objective: This study aims to evaluate the features of important comorbidities among stroke patients in the Indonesian population. Methods: The data was taken from the 2014–2015 Indonesian Family Life Survey (IFLS-5), which represents 83% of the Indonesian population. Data were analyzed by means of logistic regression models using statistical software for data science (STATA) 13. Results: There was a statistically significant relationship between stroke history and several comorbidities risk factors. The risk of stroke increases in individuals with hypertension (odds ratio (OR): 7.97, 95% confidence interval (CI): 5.19-12.26), diabetes (OR: 1.90, 95% CI: 1.14-3.15), heart disease (OR: 2.67, 95% CI: 1.47-4.85), and hyperlipidemia (OR: 3.68, 95% CI: 2.40-5.64). Of the 309 stroke patients, 41.9% had one comorbid condition; 24.1% had two; and 10.5% had three. Comorbidities increase with age, and 80.50% of stroke patients with comorbidities are aged 50 years or more. Conclusion: This study showed that the most common comorbidities in stroke patients in Indonesia are hypertension, hyperlipidemia, and diabetes.
The Relationship between Level of D-Dimer Serum with Mortality in Acute Stroke Patiens with COVID-19 Tarmidi, Moch Syahrial Pramudia; Bahrudin, Mochamad
Magna Neurologica Vol. 2 No. 2 (2024): July
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v2i2.955

Abstract

Background: COVID-19 has significantly increased morbidity and mortality in Indonesia, particularly at Gambiran General Hospital in Kediri, East Java, following the WHO's pandemic declaration. The global incidence of acute stroke with COVID-19 is 1.4%, presenting varying clinical features from mild to severe outcomes, and even death. The identification of specific biomarkers, such as elevated D-dimer serum levels, is crucial for predicting severe complications in acute stroke patients with COVID-19. Objective: This study aimed to explore the correlation between elevated levels of mild, moderate, and severe D-dimer serum and mortality in acute stroke patients with COVID-19. Methods: Conducted as an observational analytical study using a cross-sectional approach, this research utilized secondary data from medical records at Kediri Gambiran General Hospital (March 2020 to June 2023). Inclusion and exclusion criteria were applied to hospitalized patients, categorized based on D-dimer levels: normal, mild, moderate, and severe. Statistical analyses, including the Spearman correlation test and Chi-square correlation test, were employed to assess the relationship between D-dimer levels and total mortality. Results: Among the 101 enrolled patients, 53 were male (52.48%), with 90 exhibiting elevated D-dimer levels. Out of these, 44 patients died. The Spearman correlation test showed a non-significant value of 0.069 (p>0.005). The Chi-square correlation test for mild, moderate, and severe D-dimer levels on total mortality also yielded a non-significant value of 0.878. Conclusion: This study found no significant relationship between elevated levels of mild, moderate, and severe D-dimer serum and mortality in acute stroke patients with COVID-19 at Gambiran General Hospital.
Pain Detect as A Tool for The Screening of Neuropathic Pain in Patients with Diabetes Mellitus Maulidia, Agnes Annurul; Kurniawati, Media Yuni; Then, Andreas Adiwinata
Magna Neurologica Vol. 2 No. 2 (2024): July
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v2i2.957

Abstract

Background: Diabetic neuropathy (DN) is a prevalent long-term complication of diabetes mellitus (DM), affecting more than 50% of patients. In addition, several studies also showed that distal symmetric polyneuropathy (DSPN) accounts for 75% of all DN cases. To facilitate the treatment of DN, painDETECT questionnaire, a self-reported tool with 85% sensitivity and 80% specificity, has been recommended for detecting neuropathic component in pain. Objective: This study aimed to promptly diagnose DN using painDETECT questionnaire in DM patients. Methods: The study procedures were carried out using a descriptive, cross-sectional design with 67 DM patients from Cibabat Regional Hospital Department of Internal Medicine outpatient clinic through consecutive sampling in October–November 2022. Primary data were obtained using the adapted and validated Indonesian painDETECT questionnaire. Results: Among the 67 patients, 32.9% experienced neuropathic pain with a score of 19–38, indicating the involvement of >90% of neuropathic pain components. Sensory deficits, such as numbness, burning sensation, pins-and-needles, and allodynia, were observed in 86.3%, 90.1%, and 72.7% of patients with neuropathic pain, respectively. In addition, a total of 59.7% of participants (n=40) reported the presence of mild pain (NRS 3). Conclusion: Based on the results, the majority of patients had complaints of neuropathic or mild pain (40 subjects; 59.7%). Among the 22 patients experiencing neuropathic pain, 54.5% reported mild intensity.
Profile of HIV/AIDS Patients with Neurological Manifestations in The Tertiary Referral Hospital in Bali Suryapraba, Anak Agung Ayu; Vania, Aurelia; Sudewi, Anak Agung Raka; Sukmawati, Ni Made Dewi Dian; Susilawathi, Ni Made
Magna Neurologica Vol. 2 No. 2 (2024): July
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v2i2.1097

Abstract

Background: Neurological manifestations in approximately half of Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) patients are related to high morbidity and mortality worldwide. Therefore, there is a need for epidemiological data on HIV/AIDS patients with neurological manifestations in Bali, as an international tourism destination.  Objective: This study aimed to describe the clinical profile of neurological manifestations among patients with HIV/AIDS in the tertiary referral hospital for Bali and Nusa Tenggara region. Methods: A descriptive-retrospective study was conducted on HIV/AIDS patients presenting with neurological manifestations hospitalized in the Neurology Department of Prof. Dr. I.G.N.G Ngoerah Hospital Denpasar from January 2018 to December 2021. Results: Among the 227 subjects included in this study, the majority were male (69.9%) and HIV positive newly diagnosed (69.2%). Furthermore, out of 126 subjects who had CD4 data, the majority were with CD4 <200 cells/mm3 (85.7%) and 53.1% were <50 cells/mm3, with ages ranging from 18 to 67 years old, at a median of 36 years old. The most common neurological signs and symptoms found were paresis/paralysis (61.7%), headache (54.6%), decreased consciousness (52.9%), and cranial nerve palsy (52%). Cerebral toxoplasmosis (67.4%) and tuberculous meningoencephalitis (20.3%) were the prevalent opportunistic infections, while the mortality rate was 39.6% with sepsis as the major cause. Conclusions: Neurological manifestations are common initial symptoms in diagnosing HIV infection. Therefore, better awareness and earlier detection are required among people with risk factors of HIV transmission, particularly in groups of young and productive age with signs of immunocompromised condition as well as neurological manifestations.
Case Report: COVID-19 and Ischemic Stroke in A 16-Years-Old Patient Cynthia; Kumalawati, July
Magna Neurologica Vol. 2 No. 2 (2024): July
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v2i2.1140

Abstract

Background: Recent reports show an increasing trend of ischemic stroke at a young age. Diseases associated with ischemic stroke at a young age, namely hereditary hypercoagulable conditions. Case: In this case a 16-year-old boy with clinical complaints of sudden weakness of the right hand and leg, numbness, loss of appetite, nausea and vomiting. Laboratory tests showed results of increased levels of hemoglobin, hematocrit, erythrocyte count, platelet count, leukocyte count and NLR. The neutrophil-to-lymphocyte ratio (NLR), calculated as a simple ratio between the neutrophil and lymphocyte counts measured in peripheral blood. CT scan examination showed acute infarction in the medial left temporal lobe and old infarction in the left frontal lobe (medial gyrus). Thoracic CT Scan examination showed the results of bilateral pneumonia suggestive of viral. The patient encountered COVID-19. The patient experienced cough and shortness of breath and showed abnormal ABG results, namely respiratory alkalosis, decreased oxygen saturation, fever, increased procalcitonin and increased cardiac markers. Discussion: This case report prompts discussions on various aspects of ischemic stroke in young patients, including the role of COVID-19, hypercoagulable states, hematological abnormalities, and diagnostic challenges, with implications for patient management and future research directions. Conclusion: SARS CoV-2 can affect the nervous system through several mechanisms that cause persistent infection, resulting in neurological diseases, including stroke. Young ischemic stroke is usually hypercoagulable and the most common cause is APS. In this patient, polycythemia was occured,that causes blood flow slows and oxygen supply to the brain is reduced. This can cause ischemic stroke.
Olfactory Neuroblastoma with Intracranial Extension Nurwahyu Putra Romadhani, Andry; Imanuddin, Iqbal; Tejomukti, Teddy; Watanabe, Yasuhiro; Murakami, Takenobu; Tajiri, Yuki
Magna Neurologica Vol. 2 No. 2 (2024): July
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v2i2.1164

Abstract

Background: Olfactory Neuroblastoma (ONB), so called esthesioneuroblastoma, is a rare malignant tumor of the sinonasal tract. ONB represents 6.3% of all sinonasal tract malignancies, with a prevalence of 0.4 cases per million population. These tumors are slow-growing and there may be intracranial extension of the tumor. Nasal obstruction, anosmia, recurrent epistaxis and pain are typical early manifestations. Imaging studies are essential in determining tumor extension and surgical planning of ONB. Endonasal biopsy is required to confirm the diagnosis of ONB. The case provides a basis for discussion of ONB and highlights the possibility of extension of this tumor. Case: A 45-year-old male presented with a generalized clonic seizure, conjugate eye deviation, and pre-seizure headache. Post-seizure, the patient was unconscious and incontinent, later appearing conscious but confused. The patient had a history of seizures at home and in the ER, along with occasional headaches over the past year. The patient described nasal congestion, decreased smell, and recurrent nosebleeds, having undergone ethmoidectomy in 2020 for papilloma. Discussion: The patient experienced symptoms of seizures, headache, and nasal disturbances. Olfactory neuroblastoma (ONB) tumor was detected after comprehensive examination. Treatment involves multimodal therapy, including surgery, chemotherapy, and radiotherapy, with prognosis depending on tumor stage and grade. Conclusion: Early diagnosis of ONB is necessary to prevent further tumor progression. Intracranial extension of the ONB should be carefully investigated. Imaging as well as histopathological and immunohistochemical examinations are very helpful in identifying the location, metastasis and degree of malignancy of the tumor.
Management of Preoperative Meningioma Embolisation: First Case Report at Dr Soeradji Tirtonegoro Hospital Klaten Fauzi Novia Isnaening Tyas; Huda Syahdan Al Hadad; Mianoki, Adika
Magna Neurologica Vol. 3 No. 1 (2025): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i1.909

Abstract

Background: Meningioma is the most common primary central nervous system tumor among benign brain tumors. Clinical manifestations vary based on the tumor's location and size, with some patients being asymptomatic and others experiencing neurological deficits. Symptomatic meningioma patients often undergo surgical management. Preoperative embolization has been shown to reduce surgical complications by minimizing intraoperative bleeding and shortening the procedure's duration. Case: A 47-years-old woman presented with progressive right limb weakness, recurrent headaches, blurred vision, and vomiting over three months, worsening in the past week. Neurological examination revealed XII nerve paresis and limb weakness. Imaging studies identified a sizeable intracranial mass with perilesional edema, leading to a diagnosis of meningioma. The patient underwent preoperative endovascular embolization followed by craniotomy and tumor excision, resulting in a favorable postoperative outcome. Her postoperative course was uneventful, with significant improvement and regular follow-up at Dr. Soeradji Tirtonegoro General Hospital. Discussions: Preoperative embolization is beneficial for selected patients with intracranial meningiomas, especially those with highly vascular tumors. This technique effectively reduces intraoperative bleeding and surgical duration, decreasing the risk of complications. Advances in embolization techniques and materials have significantly improved outcomes and expanded their applicability. Ongoing research continues to refine and optimize meningioma management, enhancing surgical success and patient prognosis. Conclusion: This case demonstrates the effectiveness of preoperative embolization in managing intracranial meningiomas. The technique reduces intraoperative complications and improves postoperative recovery, emphasizing its critical role in optimizing surgical outcomes for meningioma patients.
The Correlation Between Cervical Provocation Tests and Compression Severity in EMG Findings of Cervical Root Syndrome Patients Zahra, Farah Shabri Alifia; Kurniawan, Shahdevi Nandar; Petrarizky, Alfred Julius
Magna Neurologica Vol. 3 No. 1 (2025): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i1.939

Abstract

Background: Medical professionals are often found using cervical provocation tests and Electromyography (EMG) examination to diagnose Cervical Root Syndrome (CRS). Although EMG examinations are unavailable in primary health care facilities due to the lack of equipment, the results of cervical provocation tests are expected to correlate with the findings of the EMG examination. Objective: This study aimed to investigate the correlation between cervical provocation tests (Lhermitte and Spurling) and compression severity of CRS. Methods: 85 medical records that met the inclusion and exclusion criteria were selected using a stratified random sampling method. Subsequently, cervical provocation tests were scaled ordinal, stratified into negative, positive 1, and positive 2, while compression severity was grouped into mild, moderate, and severe. The data obtained was analyzed using SPSS, and correlation analysis was conducted using the Spearman method. Results: The result showed that cervical provocation tests had a very weak negative correlation with the CRS compression severity, and the values obtained were not statistically significant (R = -0.105 and p = 0.341). Conclusion: The results showed that there was no significant correlation between cervical provocation tests and CRS compression severity. Therefore, cervical provocation tests cannot be depended on as a representation of CRS compression severity.
Rivaroxaban as A Therapy in Cerebral Venous Thrombosis (CVT): A Systematic Review Nafi', Maisan; Permatasari, Agnes Ardelia; Adhitama, Adrianus Setyawan
Magna Neurologica Vol. 3 No. 1 (2025): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i1.1070

Abstract

Background: Cerebral venous thrombosis (CVT) can be fatal if untreated. The European Stroke Organization recommends Low Molecular Weight Heparin in the acute phase and oral anticoagulants (VKA) for 3-12 months post-acute to prevent recurrence. Rivaroxaban, a Direct Oral Anticoagulant (DOAC) inhibiting factor Xa, is associated with reduced risks of fatal bleeding and intracranial hematoma. This systematic review aims to evaluate the efficacy and safety of Rivaroxaban therapy in CVT patients. Objective: To evaluate the efficacy and safety of Rivaroxaban therapy in patients with cerebral venous thrombosis (CVT), particularly post-acute phase, through a systematic review of relevant studies. Methods: Our review based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines with an electronic search using PubMed, Cochrane, Sage, Embase, and Ebsco published between 2012 and 2022. This study included patient with CVT above 18 years old, confirmed by radiographic examination. Results: From 339 studies we found, 6 studies were included with 113 participants who completed the research program. Major bleeding was 2.26% (n=3).Venous thromboembolism was 1.7% (n=2). Recurrent CVT was 1.7% (n=2). Score of mRS 0-1 was 76% (n=86), mRS score 2 was 2.6% (n=3) while 21 subject in a study were evaluated with NIHSS. Death was found 1.7% (n=2) which caused still unknown. Recanalization in 6-12 months both partial and complete was reported 66.3% (n=75), no recanalization was 1.7% (n=2), no recanalization evaluation was found 30.9% (n=35). Conclusion: Rivaroxaban appeared to be safe and has good efficacy as a therapy in patient with CVT after acute phase.

Page 3 of 6 | Total Record : 52

 1   2   3   4   5 

Filter by Year

2023 2025


Reset
Filter By Issues
All Issue Vol. 3 No. 2 (2025): July Vol. 3 No. 1 (2025): January Vol. 2 No. 2 (2024): July Vol. 2 No. 1 (2024): January Vol. 1 No. 2 (2023): July Vol. 1 No. 1 (2023): January