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Jurnal Medika Farmaka
Published by Sekolah Tinggi Ilmu Kesehatan Karsa Husada Garut
ISSN : -     EISSN : 2987372X     DOI : https://doi.org/10.33482/jmedfarm.v1i3
Core Subject : Science, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology
Jurnal Medika Farmaka (JMF) adalah jurnal ilmiah di bidang kefarmasian yang dikelola oleh program studi D-3 Farmasi STIKes Karsa Husada Garut di bawah naungan LP4M STIKes Karsa Husada Garut. JMF telah memiliki e-ISSN 2987-372X dengan Nomor SK: 2987372X/II.7.4/SK.ISSN/06/2023) sejak 07 Juni 2023 dan berlaku mulai dari Volume 1 No. 1, April 2023. Jurnal ini diinisiasi oleh "Ikatan Apoteker Indonesia" (IAI) Kabupaten Garut sejak tahun 2023. JMF menerima naskah artikel dalam dua area utama di bidang farmasi diantaranya: Sains Farmasi Biologi Farmasi & Farmakognosi Kimia Farmasi Analisis & Kimia Medisinal Teknologi Farmasi & Farmasetika Farmakologi & Toksikologi Bioteknologi Farmasi Klinis & Komunitas. Farmasi Rumah Sakit Farmasi Klinis Manajemen Farmasi Farmasi Sosial
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 39 Documents
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PENGARUH PEMBERIAN SEDUHAN HERBA SELEDRI (Apium graveolens L.) TERHADAP PENURUNAN KADAR ASAM URAT DALAM DARAH PADA PASIEN LANSIA Nency Wahyuni Nency Wahyuni; Aceng Ali Awaludin Aceng
Jurnal Medika Farmaka Vol 1 No 01 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i01.1

Abstract

Uric acid is the end product of purine metabolism, uric acid produced by the body is called endogenous uric acid while that which comes from food is called exogenous uric acid. Uric acid is produced by the body around 80-85%, while the rest comes from food consumed. Stewed celery contains apiin and apigenin which can be used as a treatment for gout. It is considered safer because it produces fewer side effects and does not require too much money. This study aims to examine the effect of steeping celery herb on reducing uric acid levels in the elderly. Research at the Cisandaan Clinic This research used an experimental design with a pretest-posttest with a control group. Sampling technique with simple random sampling technique. The number of samples is 34 elderly, 17 elderly in the intervention group and 17 elderly in the control group. Respondents in the intervention group were checked for uric acid levels before and after being given the infusion. Before giving the steeping of celery herb, the average uric acid level of the respondents was 7.3 mg/dl, after being given the average uric acid level of the respondents was 6.0 mg/dl. Statistical analysis using the Paired T-Test with test results on 17 elderly in the intervention group showed a decrease in uric acid levels with a p-value of 0.000 (p <0.05). This shows that there is an effect of giving celery herb infusion on reducing uric acid levels in the elderly. In conclusion, based on the results of the study, there was an effect of steeping celery herb on reducing uric acid levels in the elderly. Giving this infusion can be used as a therapy for reducing uric acid levels in the elderly by doing it regularly with 200cc every morning.
AKTIVITAS ANALGETIK EKSTRAK ETANOL DAUN CIPLUKAN (Physalis angulata L.) PADA MENCIT SWISS WEBSTER JANTAN DENGAN METODE SIEGMUND Nurul, Nurul; Risrina Nur Ekawati, Risrina Nur Ekawati
Jurnal Medika Farmaka Vol 1 No 1 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i1.2

Abstract

Pain is an unpleasant sensory and emotional experience resulting from tissue damage. Pain is a multidimensional sensory experience. These phenomena can differ in intensity (mild, moderate, severe), quality (blunt, burning, sharp), duration (transient, intermittent, persistent), and spread (superficial or deep, localized or diffuse). The use of analgesics as pain medication has been widely used by the community. the use of NSAID class analgesics is more often used. However, long-term use has side effects such as cardiovascular and gastrointestinal complications. People prefer traditional medicine as an alternative. Traditional medicine has been used by the people of Indonesia since the time of the kingdom, the struggle for independence, until the development and progress to date, one of the traditional medicines is ciplukan. The ciplukan plant is known as a plant that has many uses. One of them is ciplukan leaves which contain alkaloids and flavonoids. In this study, the analgetic activity test of Ciplukan Leaf Ethanol Extract was carried out in mice using the Siegmund method, considering that part of the ciplukan leaf is a waste that is rarely used, it is hoped that the utilization of cilukan leaf can contribute to environmental sustainability in addition to its potential in analgesic treatment. Ciplukan leaves were studied in Swiss Webster mice at doses of 10, 25, 50 mg/KgBW using the Siegmund method to determine their analgesic activity. The comparison drug used was Ibuprofen 50/70 kgBB, mice were induced intraperitoneally with 1% acetic acid. After 30 minutes of drug administration according to treatment, then observed every 5 minutes every 60 minutes. The observation results showed that all doses had analgesic activity with the most effective dose being 50 mg/KgBB.
DIFFERENCES IN HEMOGLOBIN LEVELS OF CONVENTIONAL SMOKERS AND MIXED SMOKERS (CONVENTIONAL AND ELECTRIC) Dadang Muhammad Hasyim, Dadang Muhammad Hasyim; Dina Nirwana Suwinda, Dina Nirwana Suwinda; Gina Nafsa Mutmainna, Gina Nafsa Mutmainna
Jurnal Medika Farmaka Vol 1 No 1 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i1.3

Abstract

Smoking is one of the biggest concerns in the world of health today because until now cigarettes are still the main cause of death and disease. Conventional cigarettes are processed tobacco products that are wrapped in paper to form cylinders. Vape is an alternative to conventional cigarettes allegedly safer than conventional cigarettes. Research This study aims to determine the difference in hemoglobin levels of conventional smokers and mixed smokers (conventional and electric). Qualitative method with comparative survey technique. The samples in this study were conventional smokers and mixed smokers. Consisting of 30 samples, 15 samples of conventional smokers and 15 samples of mixed and used smokers. The results of independent t test. The value of Sig. (2 tailed) of 0.018 more than 0.05, then there is a significant (significant) difference between the hemoglobin (hb) of conventional smokers and mixed smokers. Further research can continue research in analytical form with different, specific and more developed parameters. Comparison of hemoglobin levels in conventional smokers and mixed smokers, and pay attention to the brand in e-cigarettes (vapor).
ANTIBACTERIAL ACTIVITY TEST OF ETHYL ACETATE EXTRACT OF BANANA KEPOK (MUSA PARADISIACA L) AGAINST STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI BACTERIA BY AGAR DIFFUSION METHOD Yogi Rahman Nugraha, Yogi Rahman Nugraha; N. Ai Erlinawati, N. Ai Erlinawati; Eri Susanti Dewi, Eri Susanti Dewi
Jurnal Medika Farmaka Vol 1 No 1 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i1.4

Abstract

Bacterial infection is a health disorder that can be transmitted from one person to another. Bacteria that cause infectious diseases include Staphylococcus aureus and Escherichia coli. In the kepok banana hump, there are secondary metabolites such as saponins, glycosides and tannins that act as antibacterial. The purpose of this study was to determine the antibacterial activity of ethyl acetate extract of kepok banana weevil (Musa paradisiaca L.) against Staphylococcus aureus and Escherichia coli. The stages of the research began with the collection of materials, determination, processing of materials, making of ethyl acetate extraction, concentration of extracts, testing of antibacterial activity. The research method used a laboratory experiment using the disc diffusion method. Kepok banana weevil extraction was carried out using the maceration method with ethyl acetate, the antibacterial activity was tested using the agar diffusion method. The results of the antibacterial test against S. aureus bacteria in the ethyl acetate extract of kepok banana boggol (Musa paradisiaca L.) with concentrations of 0.3µg, 0.5µg, 0.6µg resulted in an average inhibition diameter of 7.1 mm, 7.7 mm, and 10.2 mm these three concentrations had an antibacterial effect in the category of resistant less than14 mm. In the positive control using the antibiotic chloramphenicol, an average inhibition zone of 21.3 mm was produced, including the Susceptible 19 mm category, while the negative control using ethyl acetate did not form an inhibition zone. In Escherichia coli bacteria At concentrations of 0.3 g, 0.5 g, 0.6 g of ethyl acetate extract of kepok banana boggol (Musa paradisiaca L.) the diameter of the inhibition zones averaged 6.9 mm, 7.6 mm, and 8.3. mm, these three concentrations had an antibacterial effect in the category of resistant less than 14 mm. In the positive control, chloramphenicol produced an average inhibition zone of 20.8 mm, including the Susceptible 19 mm category, while in the negative control using ethyl acetate, no inhibition zone was formed.
DRUG PRESCRIBING IN PATIENTS WITH ACUTE RESPIRATORY INFECTIONS AT THE TAROGONG HEALTH CENTER, GARUT DISTRICT Diah Wardani, Diah Wardani; Andra Arista Setiani, Andra Arista Setiani
Jurnal Medika Farmaka Vol 1 No 1 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i01.5

Abstract

Acute respiratory infection is a major cause of infectious disease morbidity and mortality in the world. ARI is an acute inflammation of the upper and lower respiratory tract caused by microbial, bacterial or viral infection without or with lung parenchyma. ARI has a disease group with the highest absenteeism rate compared to other disease groups and is also suffered by many people. The purpose of this study was to determine the description of drug prescribing in patients with acute respiratory infections at the Tarogong Health Center, Garut Regency. This research using descriptive methods with retrospective data collection, data collection is done by simple random sampling technique. The results of this study were patients with ISPA, which were mostly female patients with a percentage of 52.98percent as many as 142 people and men with a percentage of 47.01percent as many as 126 people. The data sample regarding the age of late adolescence 17 untill 25 years is the most cases with a percentage of 22.38 percent as many as 60 people. Based on the classification of ARI drugs that are more widely used are antibiotics with a percentage of 29.77percent as many as 268 people, analgesics-antipyretics with a percentage of 27.44percent as many as 247 people, expectorants with a percentage of 20.33 percent as many as 183 people, antihistamines with a percentage of 13.22percent as many as 119 people, corticosteroids with a percentage of 8.22percent as many as 74 people, bronchodilators with a percentage of 1 percent as many as 9 people. Based on the type of ISPA the most widely used drugs were amoxicillin with a percentage of 71.26 percent as many as 191 people, paracetamol with a percentage of 70.89 percent as many as 190 people, chlorpheniramine maleate with a percentage of 36.94percent as many as 99 people. From these data, it can be concluded that female late adulthood suffers from ISPA, the most widely used drugs are amoxicillin, paracetamol, chlorpheniramine maleate, glyceryl guaiacolate, salbutamol and dexamethasone
ASSESSMENT OF PRESCRIPTIONS BASED ON ADMINISTRATIVE ASPECTS IN HYPERTENSIVE PATIENTS AT THE GARUT DEVELOPMENT HEALTH CENTER Dani Sujana, Dani Sujana; Yoga Trisyan, Yoga Trisyan
Jurnal Medika Farmaka Vol 1 No 1 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i1.6

Abstract

Prescription review is the process of checking prescriptions for the first time after the prescription is received. Prescriptions based on administrative aspects are the initial screening when prescriptions are served which aims to analyze any problems related to treatment so as to minimize the occurrence of medication errors in prescriptions. This study aims to examine the administrative completeness of prescriptions at the Garut City Development Health Center. The data was taken primary or the latest data as many as 223 recipes. The results showed that the administrative completeness of the prescription included prescription date 100, patient name 100 age 100percent, gender 100percent, address 100, weight 0%, doctor’s name 35.1percent prescription 55.1percent doctor’s initials 0. Based on the results of the study, then it can be concluded that the prescriptions studied at the Garut City Development Health Center have incomplete prescriptions based on the Minister of Health Regulation no.74 of 2016 concerning pharmaceutical Service Standards in Puskesmas.
Efektivitas Hambatan Ekstrak Etanol Daun Muda, Tua dan Sangat Tua Bambu Surat (Gigantochloa pseudoarundinacea) terhadap Bakteri Streptococcus pyogenes Mamay; Nugraha, Yogi Rahman; Mulya Ulfah, Sri
Jurnal Medika Farmaka Vol 1 No 2 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i2.7

Abstract

Introduction: Streptococcus pyogenes is a pathogenic bacterial upper respiratory tract that cause various diseases, and the most common cause of bile pharyngitis. This bacteria has a sensitivity to penicillin G. This study aims to determine differences of inhibition effectiveness of ethanol extract of green leaves, ripe and very ripe greater giant bamboo (Gigantochloa pseudoarundinacea) to Streptococcus pyogenes bacteria Method: This type of research is experimental research with the Kirby Bauer method. The treatment group used paper discs that had been diffused from the ethanol extract of young, old and very old leaves of bamboo at a concentration of 100% on Mueller Hinton Agar media that had been planted with Streptococcus pyogenes Result: The inhibition zone obtained from extracts of young leaves was 0.28 mm, old leaves were 11.40 mm, very old leaves were 11.80 mm Conclusion The effectiveness inhibition of Streptococcus pyogenes bacterial growth for the ethanol extract of young bamboo leaves was classified as weak, the ethanol extract for old and very old leaves was classified as strong. Suggestions for further research, for selecting good leaves are very old leaves and using a different solvent for extraction solvents.
Studi Literatur Pemanfaatan Tanaman Suku Zingiberceae sebagai Antidepresan Afifah, Aminia; Kurniadi, Dede; Nurul; Wardani, Diah
Jurnal Medika Farmaka Vol 1 No 2 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i2.8

Abstract

Introduction: Depression is a mental disorder characterized by persistent depressed feelings that can affect mood, behavior and physical health. Based on basic health research data in 2018, the total number of cases affected by depression in Indonesia at the age of more than 15 years reached 6.1%. Depression therapy generally uses antidepressant drugs. The side effects of antidepressant drugs are not light, therefore it is necessary to explore plant-based medicine to treat mental disorders. Therefore, to avoid the side effects caused by these antidepressant drugs, alternative medicine from plants can be used. One of the plants that have the potential as an antidepressant is from the Zingiberaceae family. Method: The method used in writing is by conducting a literature study related to plants of the Zingiberaceae family which have the potential to have antidepressant activity contained in national and international journals published in the last 10 years. Result: Based on the results of literature research, there are several plants that have potential as antidepressants, there are 5 plants from the Zingiberaceae family, including Turmeric (Curcuma longa L), Temulawak (Curcuma xanthoriza), Temugiring (Curcuma heyneana), Black turmeric (Curcuma caseia) and the last namely Ginger (Zingiber officinale Rosc). Plants that have the greatest antidepressant activity are Curcuma heyneana plants with doses of 100 and 200 mg/kg. Conclusion. With the preparation of this paper, it is hoped that it can provide scientific information about plants that have the potential as antidepressants derived from plants of the Zingiberaceae family which can be used as an alternative treatment for depression mental illness.
Formulasi Dan Evaluasi Sediaan Gel Tabir Surya Dari Serbuk Cangkang Telur Ayam Ras (Gallus Gallus) Dengan Variasi Basis Gel Carbopol 940 Dan HPMC Sukmawati; Yuliani, Elsa
Jurnal Medika Farmaka Vol 1 No 2 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i2.9

Abstract

Introduction: Egg shells of purebred chickens (Gallus gallus) are one of the wastes that contain active calcium compounds, especially calcium carbonate compounds which have a physical blocker mechanism of action in sunscreens by reflecting UV radiation to form an opaque layer on the surface of the skin. Method: Method: This research method was experimental in the laboratory by making 4 sunscreen gel formulas from purebred chicken eggshell powder with a concentration of 15% consisting of F0 without base, F1 Carbopol 940 0.5% and 1% HPMC, F2 Carbopol 940 0.75% and HPMC 0.75%, F3 Carbopol 940 1% and HPMC 0.5%. Evaluation of sunscreen gel preparations included the stability of the preparation in the organoleptic test, homogeneity test, pH test, viscosity test, spreadability test, adhesion test and microbial contamination test. Result: All sunscreen gel preparation formulas show a brownish-white color, thick texture, characteristic odor, and are homogeneous. The pH value is 7. The adhesion value is > 1 second. Spread power value 5-7 cm. Viscosity values ​​in the range of 2000-50,000 cps. The results of the stability test at room temperature, cold temperature and hot temperature remained stable during 28 days of storage, there were no changes from organoleptic observations, homogeneity and pH, but there was a decrease in the viscosity value at room temperature and hot temperature storage and a change in the color of the preparation at hot temperatures. And the results of the microbial contamination test with the Total Plate Count test of the 4 formulas met the requirements of <102 colonies/mL. Conclusion. Based on this, it can be concluded that purebred chicken egg shell powder (Gallus gallus) can be formulated into a facial serum cosmetic preparation and meets the quality requirements according to SNI.
Gambaran Pengetahuan Masyarakat tentang Vaksin Covid-19 di Dusun Manis Desa Padarek Kabupaten Kuningan Marlinda Sari, Liska; Puspa Dynesha, Bella
Jurnal Medika Farmaka Vol 1 No 2 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i2.10

Abstract

Introduction: Covid-19 vaccine is one of the government's breakthrough to fight and handle Covid-19 in the world, especially in Indonesia. In Kuningan Regency, especially in Padarek Village, the vaccination rate has not reached 100%. As of July 25, 2022, the first dose has reached 80%, the second dose has reached 73.9%, and the third dose has reached 12.6%. Methods: The purpose of this study is to describe the knowledge of the community about the Covid-19 vaccine in Padarek Village, Kuningan Regency in 2022. Results: Based on the results of the study, it was concluded that the majority of respondents were in the vulnerable age group (46-55 years). Of the 100 respondents, 54% of the people in Padarek Village have good knowledge about Covid-19 vaccines, 39% have sufficient knowledge, and 7% have less knowledge. This is due to the lack of information about Covid-19 vaccines. 68% of respondents are willing to get vaccinated against Covid-19, while 32% are not willing to get vaccinated for several reasons. Conclusion: The results of this study reported that more than half of the people in Padarek Village have good knowledge, while less than half have sufficient knowledge, and a small portion have less knowledge about Covid-19 vaccines.

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