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Andhika Lungguh Perceka
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Jurnal Medika Farmaka
Published by Sekolah Tinggi Ilmu Kesehatan Karsa Husada Garut
ISSN : -     EISSN : 2987372X     DOI : https://doi.org/10.33482/jmedfarm.v1i3
Core Subject : Science, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology
Jurnal Medika Farmaka (JMF) adalah jurnal ilmiah di bidang kefarmasian yang dikelola oleh program studi D-3 Farmasi STIKes Karsa Husada Garut di bawah naungan LP4M STIKes Karsa Husada Garut. JMF telah memiliki e-ISSN 2987-372X dengan Nomor SK: 2987372X/II.7.4/SK.ISSN/06/2023) sejak 07 Juni 2023 dan berlaku mulai dari Volume 1 No. 1, April 2023. Jurnal ini diinisiasi oleh "Ikatan Apoteker Indonesia" (IAI) Kabupaten Garut sejak tahun 2023. JMF menerima naskah artikel dalam dua area utama di bidang farmasi diantaranya: Sains Farmasi Biologi Farmasi & Farmakognosi Kimia Farmasi Analisis & Kimia Medisinal Teknologi Farmasi & Farmasetika Farmakologi & Toksikologi Bioteknologi Farmasi Klinis & Komunitas. Farmasi Rumah Sakit Farmasi Klinis Manajemen Farmasi Farmasi Sosial
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 51 Documents
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Profil Kajian Administratif dan Ketepatan Resep Obat Antihipertensi di Puskesmas Darma Kabupaten Kuningan Anugra Diputra, Angga; Febriliana, Gina
Jurnal Medika Farmaka Vol 1 No 2 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i2.11

Abstract

Introduction: There are still many problems with prescription completeness, such as incomplete patient information. Hypertension is one of the most common cardiovascular diseases and the cases most often occur in the community. The high number of cases of hypertension or its complications causes the use of antihypertensive drugs to increase, and the chances of inappropriate drug selection in hypertensive patients are higher. The purpose of this study was to determine the percentage of completeness of prescriptions and the accuracy of drug selection in outpatient hypertension patients at the Darma Health Center for the period July - December 2020 when viewed based on the right drug and the right dose. Methods: The type of research carried out is non-experimental observational research. Data collection was carried out retrospectively through outpatient medical records of hypertension patients for the period July - December 2020. The sampling method used in this study was purposive sampling. Results: From a total of 570 prescriptions for hypertension patients, a sample of 85 patients was used. The results of the administrative review of prescriptions obtained 100% patient data completeness, 100% doctor's name, 100% doctor's initials, 100% prescription writing date and 100% prescription room/unit. The results of the evaluation of the accuracy of antihypertensive drug prescriptions showed that the accuracy of prescribing based on the correct criteria for the drug was 71,8% and based on the criteria for the correct dose of 100%. Conclusion: This study revealed that the administrative compliance and accuracy based on the right dose criterion of antihypertensive drug prescriptions were all in compliance, but there were still discrepancies for the right drug criterion.
Mutu Fisik dan Daya Terima Body Scrub dengan Variasi Konsentrasi Sari Buah Nanas (Ananas comosus (L.) Merr) Ambarwati, Rini; Wulandari, Asri; Herlina, Eka
Jurnal Medika Farmaka Vol 1 No 2 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i2.12

Abstract

Introduction: Pineapple fruit contains vitamins such as vitamin C, vitamin A, vitamin B1, and vitamin B6, which are good for the skin and overall health. Body scrub is one of the skin care products that functions to remove dead skin cells and smoothen the skin so that the skin will be healthier. This study aims to find out that pineapple can also be used as an active ingredient in the formulation of body scrub preparations. Methods: In this study, pineapple juice was varied in the formulation of body scrub preparations. The evaluation of body scrub preparations includes viscosity testing, irritation, organoleptic testing with hedonic test method, pH, homogeneity, and emulsion type. Results: The results of the organoleptic testing of body scrub preparations with the hedonic test method showed that the most preferred formula was formula 1 with a pineapple juice concentration of 5%. Body scrub preparations without the addition of pineapple juice are white, while body scrub preparations with the addition of pineapple juice are ivory white and have good homogeneity. The pH and M/A type and viscosity of all formulas were obtained in accordance with the literature. Body scrub preparations do not cause irritation and are safe to use. Conclusion: The formulation of pineapple juice body scrub preparations at a concentration of 5%, 10%, and 15% have good physical quality. Body scrub preparations from pineapple juice have good physical quality and acceptability, namely in the 5% formula where the viscosity value is 5390 cp, no irritation occurs, the hedonic test results show significant differences in all formulas, homogeneous preparations, M/A type emulsion preparations, and have a pH of 6.63.
Review Artikel: Kajian Senyawa Fitokimia dan Aktivitas Farmakologi Antidiabetes dari Syzygium cumini Rustamsyah, Ardi; Perdana, Farid; Zulfakor, Dava; Kusmiyati, Mimin
Jurnal Medika Farmaka Vol 1 No 2 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i2.13

Abstract

Introduction: Jamblang is a plant from the Myrtaceae family. It can be used as a traditional medicine, one of which can treat diabetes. The purpose of this review is to determine the phytochemical compounds of Syzygium cumini that have antidiabetic activity. Methods: The methods used in the preparation of this review article are to search for various sources that discuss antidiabetic activity and phytochemical studies of Syzygium cumini. Results: The results of the review that have been carried out explain the in vitro and in vivo testing of antidiabetic activity on the inhibition method and the induction method, resulting in jamblang potentially as an antidiabetic. Conclusion:The results of the review that have been carried out explain the phytochemical study using HPLC method there are groups of flavonoid, phenolic, and phenylpropanoid compounds, and on the TLC method there are groups of terpenoids. Oleic acid and ursolic acid compounds have antidiabetic activity.
Formulasi dan Evaluasi Sediaan Patch Ekstrak Getah Batang Pisang Ambon Sebagai Penyembuh Luka Sayat Sukma; Nuralim, Bili
Jurnal Medika Farmaka Vol 1 No 3 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i3.14

Abstract

Introduction: Bananas are fruit that is easily obtained and high nutritional value. Ambon banana stem sap contains flavonoid compounds that are used to accelerate wound healing. The purpose of this study was to make a patch preparation from Ambon banana stem latex extract. Method: The type of research uses an experimental method by making several patch formulas containing Ambon banana stem latex extract with a concentration of 0%, 30%, 35%and 40%. And physical evaluation of the patch preparation includes organoleptic tests at temperatures (1º-4ºC), (25º-28ºC) and (40ºC), uniformity of weight, pH, thickness and fold resistance Result: The physical evaluation results show storage at temperatures (25º-28ºC) better and more stable, especially in organoleptic tests because they do not experience changes in shape, odor and color. The weighing uniformity test of all concentrations has an average uniformity of 0.07 and 0.08 grams. All stable formulas have a pH of 6 and in accordance with the requirements of the skin pH of 4.5-6.5. Patch thickness test concentration 0% 0.06 µm, concentration of 30%; 35 % 0.07 µm, and concentration of 40 % 0.07 µm. All concentrations meet the fold requirements ≥ 200 times the fold Conclusion Based on all physical evaluation tests conducted concentrations of 35 % and 40 % are the best and most stable preparations.
Artikel Review: Analisis Kadar Klorin pada Pembalut dengan Metode Volumetri Sahara, Khalipatun; Nurohmah, Alivia; Maelaningsih, Firdha Senja; Cahyani, Lufitha Evelyne
Jurnal Medika Farmaka Vol 1 No 3 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i3.16

Abstract

Introduction: Sanitary napkins are a hygiene product that women very commonly use during menstruation. The safety and quality of sanitary napkins are essential to prevent adverse impacts on health. One crucial aspect that needs to be considered is the level of chemical pollution, such as chlorine, which has the potential to endanger health. The volumetric method is one of the most commonly used methods to measure the chlorine content in various products. In this article, the volumetric method for analyzing chlorine content in sanitary napkins consists of three methods: iodometric titration, iodometric titration, and argentometric titration. This article aims to summarize a literature review that discusses various studies regarding the analysis of chlorine levels in sanitary napkins using the volumetric method. Method: The method used in the article review is a literature review by taking journal articles containing analysis of chlorine levels in sanitary napkins using the volumetric method. Results: A review of various studies showed variations in chlorine levels in the sanitary napkin samples tested. Conclusion: Chlorine levels in sanitary napkins can be analyzed using the volumetric method, with the chlorine results that can be analyzed being in the range of 0.0022% w/v-0.0022% w/v.
Gambaran Protein Urine pada Penderita Diabetes Melitus Tipe 2 di Puskesmas Cikajang Nafsa Mutmaina, Gina; Sugiah; Puspita, Tantri; Lestari, Nabila Ajeng Wiji
Jurnal Medika Farmaka Vol 1 No 3 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i3.17

Abstract

Introduction: Type 2 diabetes mellitus is the most common type. In patients with type 2 diabetes mellitus the pancreas can still make insulin, but the quality of insulin is poor and cannot function properly so that blood glucose increases. The presence of protein in the urine is caused by leakage of plasma proteins from the glomerulus. Clinically detected proteinuria is abnormal and is usually an early marker of kidney disease. The purpose of this study was to determine the results of urine protein examination in patients with Type 2 Diabetes Mellitus at Cikajang Health Center. The purpose of this study was to determine the results of the description of urine protein levels in patients with type 2 diabetes mellitus at the Cikajang Health Center Method: the research used was descriptive research. The population in this study was 7,338 people. The sample size in this study was 30 respondents. The sampling technique used was purposive sampling technique. The variable in this study was urine protein levels in patients with type 2 DM examined using the dipstick method. Results: The results of this study obtained negative results (-) 19 people (64%), trace (±) 8 people (26%), positive 1 (+) 2 people (7%), positive 2 (++) 1 person (3%). The results of the study can be concluded that in this study there were more negative urine protein results compared to positive urine protein results. Conclusion. It can be concluded that in this study more results were negative urine protein compared to positive urine protein.
Formulasi dan Uji Aktivitas Sediaan Emulgel Ekstrak Daun Talas (Colocasia esculenta (L). Schott) terhadap Bakteri Staphylococcus aureus, Proteus mirabilis, Escherichia coli dan Pseudomonas aeruginosa Ameliya, Helvi; Rustiani, Erni; Sulistiyono, Fitria Dewi
Jurnal Medika Farmaka Vol 1 No 3 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i3.18

Abstract

Introduction: Taro leaf (Colocasia esculenta (L). Schott) are known to contain flavonoid compounds that have antibacterial activity that causes wound infections. One of the topical dosage forms for the treatment of bacterial infections in wounds is emulgel which can convey the active substance of the drug with hydrophobic properties. Appropriate and effective topical administration is expected to reduce and prevent wound infection. This study aims to determine the antibacterial activity of taro leaf extract emulgel preparations against Staphylococcus aureus, Proteus mirabilis, Escherichia coli and Pseudomonas aeruginosa bacteria based on the width of inhibition (LDH) value. Methods: Taro leaf extract emulgel preparations were made as many as 4 formulas with different extract concentrations namely (F1) 5%, (F2) 7.5% and (F3) 10% and (F0) as a negative control containing only emulgel base. Testing of emulgel preparations includes organoleptic, homogeneity, pH, spreadability, and viscosity. Antibacterial testing using disc paper diffusion method with positive control sulfadiazine silver and negative control emulgel base. Results: The results showed that the emulgel preparation was viscous, brownish green in color, and had a distinctive smell of taro leaf extract. The mean pH values were 5.657-5.912, spreadability 5.845-6.258 cm, and viscosity 7830-9780 cps. Statistical test results of antibacterial activity of taro leaf extract emulgel with sig 0.000 <0.05 showed that all concentrations of taro leaf extract emulgel provide inhibition against bacteria. Conclusion: The best antibacterial activity was shown by 10% concentration of taro leaf extract emulgel against Staphylococcus aureus (10.69mm), Pseudomonas aeruginosa (10.50mm), Escherichia coli (10.34mm) and Proteus mirabilis (10.14mm) all with strong inhibition zone category (10-20mm).
Review Jurnal: Aktivitas Deodorant Spray Ekstrak Herbal Pada Bakteri Staphylococcus sp dengan Metode Difusi Agar Sahira Madliya, Juliettania; Rahmawati, Adelia; Ihsani, Salfia; Maelaningsih, Firdha Senja
Jurnal Medika Farmaka Vol 1 No 3 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i3.19

Abstract

Introduction: Body odor is induced by the secretion of sweat glands and bacterial activity. One way to overcome body odor is by maintaining proper body hygiene and using topical preparations such as antiperspirants and deodorants. This study aims to review several journal articles regarding herbal deodorant spray formulations against Staphylococcus bacteria based on the active compound concentration. The literature review was conducted by searching scientific articles published in the last 10 years from 2013 to 2023 using scientific databases. Methods: Several formulation methods have been identified in the reviewed articles including disc diffusion, paper disc diffusion, and agar diffusion methods. The active compounds tested were “kemangi” leaf extract, orange peel extract, and red ginger extract. Results: Showed that increasing the concentration of the active compounds was generally proportional to the increase in antibacterial activity. The optimal concentrations giving good antibacterial activity were 15% for orange peel extract, 8% for “kemangi” leaf extract, and 80% for red ginger extract. Conslusion: This review concludes that herbal extracts have the potential to develop as natural deodorant ingredients and the concentration of active compounds strongly influences the antibacterial activity. Keywords: Herbal extract, Concentration, Antibacterial activity, Test method, Positive and negative controls.
Sifat Fisik Gel Masker Peel off Sari Cucumis Sativus dengan Basis Polivinil Alkohol dan Variasi Konsentrasi Hidroksipropil Metilselulosa Fitriyani, Neng Yasmi Bella; Nurul
Jurnal Medika Farmaka Vol 1 No 3 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i3.21

Abstract

Introduction: Cucumber is a type of fruit from the gourd family (Cucurbitaceae). Cucumber has a high water content, provides a sensation of freshness, and has cooling and soothing properties on irritated skin. Peel off masks are vinyl-based formulations with advantages such as ease of use, easy rinsing and cleaning. In this study, cucumber juice can to add to the peel off mask formulation. This study evaluated the physical properties of peel off masks with polyvinyl alcohol base and varying concentrations of hydroxypropyl methylcellulose Method: The design of this study was descriptive quantitative to assess the physical properties of peel off masks. Results: The results showed that variations in PVA and HPMC bases did not affect color, odor, or taste, but only affected texture. Each formulation has a thick to thin texture. The homogeneity of the mask was not affected by the variation of PVA and HPMC bases, the pH of the preparation remained unchanged. Spreadability and dry time were affected by HPMC concentration, with smaller concentrations resulting in shorter spreadability and longer dry time. Viscosity values decreased with different stirring speeds. Conclusion: The peel off masks have relatively similar organoleptical physical properties and pH in each formula, except for diverse textures, while the concentration of PVA and HPMC is directly proportional to the dry time, spreadability and viscosity of cucumber juice peel off masks.
Review : Formulasi dan Evaluasi Tablet Hisap dan Tablet Effervescent dari Ekstrak Bahan Alam dengan Berbagai Metode Formulasi Adila Abadi, Shada; Reihan Ridha, Muhammad; Savitri, Aida; Nisa, Jannatun; Saputra, Nicky; Latifah, Nor
Jurnal Medika Farmaka Vol 2 No 3 (2024): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v2i3.37

Abstract

Introduction: Indonesians have long recognized and used medicinal plants to treat health problems. The use of natural products, especially from plants, increased by 380%. The use of natural ingredients from plants is generally still done traditionally, such as brewing, mashing, or taking the juice, which makes it difficult to determine a uniform dose, so there is a high possibility of non-uniformity in the composition of the compounds in the final product. Therefore, this is an impetus for traditional medicine manufacturers to create practical preparations, one of which is by making tablet preparations such as lozenges and effervescent tablets from natural ingredient extracts. Method: This article review is based on references from several nationally published database articles and online search instruments. Result: Based on the results of the review of several articles, 8 journals were selected that met the predetermined criteria. Conclusion. From the results of the review, it is known that natural ingredient extracts can be formulated into several types of tablet preparations such as lozenges and effervescent tablets using wet granulation, dry granulation, and direct felting methods and evaluation of tablet preparation is carried out to ensure the quality of tablet preparations. Keywords: Formulation, tablet, extract, evaluation

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