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All Journal Jurnal Medika Cendikia (e-Journal) Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Ilmiah Farmako Bahari Jurnal Kolaboratif Sains Jurnal Pengabdian Masyarakat DEDIKASI Innovative: Journal Of Social Science Research Jurnal Kemitraan Responsif untuk Aksi Inovatif dan Pengabdian Masyarakat Jurnal Medika Farmaka
Yogi Rahman Nugraha
STIKes Karsa Husada Garut
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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FORMULASI KRIM EKSTRAK ETANOL DAUN REUNDEU (Staurogyne elongata (Blume) O.Kuntze) DENGAN VARIASI KONSENTRASI PARAFIN CAIR DAN SETIL ALKOHOL Diah Wardani; Nurul Nurul; Dani Sujana; Yogi Rahman Nugraha; Resta Nurseha
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 6 No 2 (2021): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v6i2.1940

Abstract

Tujuan dari penelitian ini yaitu untuk mengetahui stabilitas krim ekstrak etanol daun reundeu (Staurogyne elongata (Blume) O.Kuntze) dengan variasi konsentrasi paraffin cair dan setil alkohol. Perbandingan konsentrasi paraffin cair dan setil alkohol yang ditambahkan pada sediaan yaitu F1 (5% dan 2%), F2 (10% dan 4%), F3 (15% dan 8%). Krim dibuat dengan cara peleburan. Metode uji stabilitas dilakukan dengan cara sediaan disimpan pada suhu kamar dan suhu 40C selama 4 minggu. Parameter pengujian fisik krim yang dilakukan meliputi uji tipe emulsi, organoleptik, daya sebar, homogenitas, viskositas, pH dan daya lekat. Penelitian yang dilakukan menunjukkan bahwa sediaan krim yang memiliki stabilitas paling baik serta memenuhi standar uji yaitu formula F1 dengan konsentrasi paraffin cair 5% dan setil alkohol 2%, dengan hasil pengujian sifat fisik (siklus 0) sediaan yaitu memiliki tipe emulsi minyak dalam air (m/a), organoleptik (bau: khas lemah etanol daun reundeu; warna: hijau; tekstur: kental), memiliki tekstur yang homogen, pH 7,3, daya lekat 7,3 detik, daya sebar 5,3 cm, dan viskositas 4.783 cP.
EVALUASI AKTIVITAS ANTIHIPERURISEMIA EKSTRAK ETANOL HERBA SURUHAN (PEPEROMIA PELLUCIDA L.), HERBA SELEDRI (APIUM GRAVEOLENS L.) DAN KOMBINASI EKSTRAK: STUDI IN VIVO BERBASIS BUKTI ILMIAH Yogi Rahman Nugraha; Dani Sujana; Yunahara Farida; Faizatun Faizatun
Jurnal Ilmiah Farmako Bahari Vol 13, No 1 (2022): Jurnal Ilmiah Farmako Bahari
Publisher : Fakultas MIPA Universitas Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jfb.v13i1.1312

Abstract

Hiperurisemia adalah suatu kondisi dimana kadar asam urat meningkat. Hiperurisemia disebabkan oleh kelainan genetik pada sistem metabolisme tubuh yang mencegah tubuh mengeluarkan asam urat dari tubuh. Flavonoid dan alkaloid merupakan senyawa yang dipercaya mampu menurunkan kadar asam urat dalam darah dengan cara menghambat kerja xantin oksidase dan superoksidase. Herba suruhan dan seledri telah lama dipakai sebagai obat tradisional untuk mengatasi keluhan asam urat. Pada penelitian ini dilaporkan bahwa ekstrak etanol seledri dan herba seledri serta ekstrak gabungan menunjukkan aktivitas antihiperurisemia yang signifikan terhadap kontrol negatif selama pengamatan (p<0,05). Dosis 250 mg/kgBB menunjukkan aktivitas paling baik (kombinasi ekstrak etanol herba suruhan (Peperomia pellucida 75%) ekstrak etanol herba seledri (Apium graveolens 25%) dengan penurunan asam urat sebesar 58,4%.
ANALGESIC EFFECT OF INFUSA MIXTURE OF RED GINGER, TEMUKUNCI, KENCUR, LEMONGRASS AND TAMARIND ON FEMALE MICE BY WRITHING TEST METHOD. Dani Sujana; Nurul; Dadang Muhammad Hasyim; Yogi Rahman Nugraha; Diah Wardani; Mina Pertiwi; Hesti Renggana
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 8 No 2 (2023): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v8i2.5929

Abstract

Pain is an unpleasant sensory and emotional experience caused by actual or potential tissue damage. Based on systematic review studies it has been proven that red ginger, temukunci, kencur, lemongrass and tamarind have been shown to have analgesic effects both in vitro and in vivo. The purpose of this study was to determine the analgesic effect of IJTKSA. The method used in this study is a laboratory experiment with an analytical descriptive approach. The results showed that IJTKSA both concentrations of 0.02%, 0.04% and 0.08% were able to reduce the number of writhing mice. Overall, IJTKSA concentration of 0.02% has the most effective analgesic effect as evidenced by the low average total number of writhing mice during 60 minutes of observation.
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL JAHE MERAH (Zingiber officinale var. Rubrum) TERHADAP BAKTERI Streptococcus mutans SECARA IN VITRO Nugraha, Yogi Rahman; Sujana, Dani; Dewi, Risma Anugrah
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 9 No 2 (2024): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v9i2.8019

Abstract

Infections remain a major public health challenge in Indonesia, including infections of the oral cavity caused by microorganisms such as Streptococcus mutans. Red ginger is known to contain flavonoids, phenols, essential oils, and tannins that have the potential to inhibit bacterial growth. This study aims to test the antimicrobial activity of red ginger ethanol extract against Streptococcus mutans using the agar diffusion method. The results showed that at concentrations of 10 and 20%, there was a slight increase in the zone of inhibition. However, starting from 40% concentration, the increase in concentration resulted in a larger zone of inhibition. At 60% concentration, the results were close to the positive control, and at the highest concentration of 80%, the inhibition zone reached 28.04 mm with an inhibition rate of 62.24%. Overall, the inhibitory activity showed a positive relationship as the concentration of red ginger extract increased.
Pemberdayaan Santri di Pondok Pesantren Manbaul Huda Seureuh Jawa Cibiuk Kabupaten Garut Dalam Pemanfaatan Limbah Organik Menjadi Ekoenzim Dadang Muhammad Hasyim; STIKES Karsa Husada Garut; Yogi Rahman Nugraha; Nurul; Elang Mohamad Atoilah; Dede Suharta; Firman Muharam
Jurnal Kemitraan Responsif untuk Aksi Inovatif dan Pengabdian Masyarakat Volume 2 Issue No. 2: January 2025
Publisher : Lontara Digitech Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61220/kreativa.v2i2.20252

Abstract

Pengelolaan limbah organik merupakan tantangan di lingkungan pesantren yang dapat menimbulkan permasalahan lingkungan jika tidak dikelola dengan baik. Program ini bertujuan untuk memberdayakan santri Pondok Pesantren Manbaul Huda di Seureuh Jawa, Cibiuk, Garut, dalam mengolah limbah organik menjadi ekoenzim, sebuah produk hasil fermentasi yang bermanfaat sebagai pupuk organik dan cairan pembersih alami. Program ini dilaksanakan melalui tahap-tahap persiapan, pelatihan, praktik produksi, pemanfaatan produk, dan evaluasi keberhasilan. Hasil pelaksanaan menunjukkan bahwa 90% santri aktif berpartisipasi dalam kegiatan dan memiliki pemahaman yang baik tentang pembuatan ekoenzim, sebagaimana dibuktikan dengan peningkatan skor post-test rata-rata sebesar 85%. Sebanyak 65 liter ekoenzim berhasil diproduksi, melampaui target awal sebesar 50 liter. Produk ekoenzim dimanfaatkan untuk kebutuhan internal pesantren dan mulai dijual ke masyarakat oleh beberapa santri, menunjukkan potensi kewirausahaan yang tumbuh. Kesadaran lingkungan di kalangan santri juga meningkat, dengan 75% santri mulai memilah limbah secara mandiri. Program ini diintegrasikan ke dalam kurikulum pesantren, menjadikannya sebagai kegiatan rutin yang berkelanjutan. Dengan pendekatan kolaboratif dan berbasis praktik, program ini berhasil menciptakan pesantren yang ramah lingkungan, mandiri secara ekonomi, dan berpotensi menjadi model pemberdayaan lingkungan yang dapat direplikasi di wilayah lain.
Efektivitas Hambatan Ekstrak Etanol Daun Muda, Tua dan Sangat Tua Bambu Surat (Gigantochloa pseudoarundinacea) terhadap Bakteri Streptococcus pyogenes Mamay; Nugraha, Yogi Rahman; Mulya Ulfah, Sri
Jurnal Medika Farmaka Vol 1 No 2 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i2.7

Abstract

Introduction: Streptococcus pyogenes is a pathogenic bacterial upper respiratory tract that cause various diseases, and the most common cause of bile pharyngitis. This bacteria has a sensitivity to penicillin G. This study aims to determine differences of inhibition effectiveness of ethanol extract of green leaves, ripe and very ripe greater giant bamboo (Gigantochloa pseudoarundinacea) to Streptococcus pyogenes bacteria Method: This type of research is experimental research with the Kirby Bauer method. The treatment group used paper discs that had been diffused from the ethanol extract of young, old and very old leaves of bamboo at a concentration of 100% on Mueller Hinton Agar media that had been planted with Streptococcus pyogenes Result: The inhibition zone obtained from extracts of young leaves was 0.28 mm, old leaves were 11.40 mm, very old leaves were 11.80 mm Conclusion The effectiveness inhibition of Streptococcus pyogenes bacterial growth for the ethanol extract of young bamboo leaves was classified as weak, the ethanol extract for old and very old leaves was classified as strong. Suggestions for further research, for selecting good leaves are very old leaves and using a different solvent for extraction solvents.
Uji Aktivitas Antibakteri Dari Ekstrak Etanol Bonggol Pisang Kepok (Musa paradisiaca L.) Terhadap Bakteri Staphylococus Aureus Dan Escherichia Coli Dengan Metode Difusi Agar Angrestian, Angga; Renggana, Hesti; nugraha, Yogi rahman
Jurnal Medika Farmaka Vol 2 No 1 (2024): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v2i1.34

Abstract

Medicinal plants that have more uses and value in traditional medicine against diseases. One of them is the kepok banana plant (Musa paradisiaca L.) as an herbal treatment the kepok banana plant is an annual shrub, this plant has a root system and rhizome Fruit only once (single fruit) then dies. Banana plants contain compounds such as flavonoids, saponins, tannins, and steroids. The method used in the research to be carried out is the experimental method. This study aims to determine the ethanol extract of kepok banana weevil (Musa paradisiaca L.) to test its antibacterial activity against Staphylococcus aureus and Escherichia coli using the agar diffusion method. In this study, the ethanol extract of kepok banana weevil (Musa paradisiaca L.) with concentrations of 2, 4, and 6 against Staphylococus aureus and Escherichia coli bacteria. In Staphylococus aureus bacteria with a concentration of 2 the average diameter of the inhibitor produced was 3.03 mm, the concentration of 4 of the diameter of the inhibitor produced was 6.4 mm, the concentration of 6 of the diameter of the inhibitor produced was 8.3 mm. In Escherichia coli bacteria with a concentration of 2 the average diameter of 6.7 mm was produced, the concentration of 4 was 7.7 mm in diameter, and the concentration of 6 was 8.2 mm in diameter. The three concentrations have antibacterial effect that is Resistant 14 mm. Ethanol extract of kepok banana weevil (Musa paradisiaca L.) can inhibit the growth of staphylococcus aureus and Escherichia coli bacteria. At concentrations of 2, 4, and 6 the ethanolic extract of the kepok banana weevil (Musa paradisiaca L.) with an average inhibitory diameter of 3.03 mm, 6.4 mm and 8.3 mm, these three concentrations had an antibacterial effect of 14 mm.
ANTIBACTERIAL ACTIVITY TEST OF ETHYL ACETATE EXTRACT OF BANANA KEPOK (MUSA PARADISIACA L) AGAINST STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI BACTERIA BY AGAR DIFFUSION METHOD Yogi Rahman Nugraha, Yogi Rahman Nugraha; N. Ai Erlinawati, N. Ai Erlinawati; Eri Susanti Dewi, Eri Susanti Dewi
Jurnal Medika Farmaka Vol 1 No 1 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i1.4

Abstract

Bacterial infection is a health disorder that can be transmitted from one person to another. Bacteria that cause infectious diseases include Staphylococcus aureus and Escherichia coli. In the kepok banana hump, there are secondary metabolites such as saponins, glycosides and tannins that act as antibacterial. The purpose of this study was to determine the antibacterial activity of ethyl acetate extract of kepok banana weevil (Musa paradisiaca L.) against Staphylococcus aureus and Escherichia coli. The stages of the research began with the collection of materials, determination, processing of materials, making of ethyl acetate extraction, concentration of extracts, testing of antibacterial activity. The research method used a laboratory experiment using the disc diffusion method. Kepok banana weevil extraction was carried out using the maceration method with ethyl acetate, the antibacterial activity was tested using the agar diffusion method. The results of the antibacterial test against S. aureus bacteria in the ethyl acetate extract of kepok banana boggol (Musa paradisiaca L.) with concentrations of 0.3µg, 0.5µg, 0.6µg resulted in an average inhibition diameter of 7.1 mm, 7.7 mm, and 10.2 mm these three concentrations had an antibacterial effect in the category of resistant less than14 mm. In the positive control using the antibiotic chloramphenicol, an average inhibition zone of 21.3 mm was produced, including the Susceptible 19 mm category, while the negative control using ethyl acetate did not form an inhibition zone. In Escherichia coli bacteria At concentrations of 0.3 g, 0.5 g, 0.6 g of ethyl acetate extract of kepok banana boggol (Musa paradisiaca L.) the diameter of the inhibition zones averaged 6.9 mm, 7.6 mm, and 8.3. mm, these three concentrations had an antibacterial effect in the category of resistant less than 14 mm. In the positive control, chloramphenicol produced an average inhibition zone of 20.8 mm, including the Susceptible 19 mm category, while in the negative control using ethyl acetate, no inhibition zone was formed.
Antibacterial Activity of Ecoenzyme from Garut Orange Peel (Citrus nobilis var.chrysocarpha) against Propionibacterium acne Nurani Ai Erlinawati, Nurani Ai Erlinawati; Mamay, Mamay; Yogi Rahman Nugraha, Yogi Rahman Nugraha
Jurnal Medika Cendikia Vol 12 No 01 (2025): Jurnal Medika Cendikia
Publisher : Karsa Husada Health Institute Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmc.v12i01.323

Abstract

Acne is a skin disorder that often occurs in adolescents. Propionibacterium acnes is a bacteria that causes acne. The use of antibacterial substances is very important to prevent and control this bacterial infection. One of the advances in the use of antibacterials comes from the use of ecoenzyme. The process of managing organic waste with ecoenzyme can be an effective and environmentally friendly waste management strategy. Garut orange with the scientific name Citrus nobilis var. chrysocarpa is a local wisdom fruit. Orange peel which is a waste that increases in quantity when the harvest season arrives can be used in the manufacture of ecoenzyme. This study aims to evaluate the antibacterial ability of ecoenzyme from garut orange peel against Propionibacterium acnes bacteria. The fermentation time for ecoenzyme production varied from 30, 60 and 90 days.. The method for the eco enzyme antibacterial test uses the disc diffusion method. Three variations in eco enzyme concentration used to inhibit the growth of isolated bacteria are 33%, 66% and 100%. Ecoenzyme from Garut orange peel shows antibacterial activity against Propionibacterium acne. Antibacterial activity shows an increase with increasing fermentation time of ecoenzyme
IMPROVING COMMUNITY HEALTH THROUGH HEALTH SCREENING FOR POSYANDU CADRES AND THE COMMUNITY OF JAYARAGA VILLAGE Andhika Lungguh Perceka, Andhika Lungguh Perceka; Hasbi Taobah Ramdani, Hasbi Taobah Ramdani; N. Ai Erlinawati, N. Ai Erlinawati; Herlin Rusyan, Herlin Rusyani; Sugiah, Sugiah; Gina Mutmainna, Gina Mutmainna; Wieda Widyatry Qarragita, Wieda Widyatry Qarragita; Dani Sujana, Dani Sujana; Yogi Rahman Nugraha, Yogi Rahman Nugraha
Jurnal Pengabdian Masyarakat DEDIKASI Vol 6 No 01 (2025): Jurnal Pengabdian Masyarakat DEDIKASI
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jdk.v6i01.161

Abstract

This Community Service Activity (PkM) aims to identify risk factors for diabetes mellitus (DM) as one of the comorbidities that exacerbate the condition of the elderly. The expected outcome of this activity is for residents to be aware of the risk factors for the disease and their own health conditions, particularly regarding DM. It is hoped that this activity will increase community awareness about DM management. The activity was attended by 50 residents of Jayaraga Village, Tarogong Kidul District, Garut Regency. The results of the activity revealed that 7 individuals (14%) confirmed having diabetes mellitus, 31 individuals (62%) had hypertension, and 12 individuals (24%) had gout. Therefore, through this community service initiative, we conducted a health screening program that included free blood pressure checks, uric acid tests, and blood sugar level measurements, as well as weight checks and health education, particularly on diabetes and its prevention methods. With the implementation of this community service initiative, we hope that the health-related issues in Jayaraga Village, Tarogong Kidul Sub-district, Garut Regency, can be addressed to some extent.
Co-Authors Angrestian, Angga Anita Kahirunnisa Ardi Rustamsyah Asep Darda darul hikam Dadang Muhammad Hasyim Dani Sujana Dani Sujana, Dani Sujana Dede Suharta Dewi, Risma Anugrah Diah Wardani Elang Mohamad Atoilah Eri Susanti Dewi, Eri Susanti Dewi Faizatun Farid Permana Firman Muharam Gina Mutmainna, Gina Mutmainna Hasbi Taobah Ramdani, Hasbi Taobah Ramdani Herlin Rusyan, Herlin Rusyani Hesti Renggana La Ode Maksar Muhuruna Mamay Mamay, Mamay Mina Pertiwi Mulya Ulfah, Sri N. Ai Erlinawati, N. Ai Erlinawati Nuralfin Anripa Nurani Ai Erlinawati, Nurani Ai Erlinawati Nurul Nurul Nurul Nurul Nurul Perceka, Andhika Lungguh Puspitasari, Siva Renggana, Hesti Resta Nurseha Rohdiana, Aulia STIKES Karsa Husada Garut Sugiah, Sugiah Susatyo Adhi Pramono, Susatyo Adhi Syswianti, Desy Wardani, Diah Wieda Widyatry Qarragita, Wieda Widyatry Qarragita Yunahara Farida