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Rina Priastini Susilowati
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Jurnal MedScientiae
Published by Universitas Kristen Krida Wacana
ISSN : -     EISSN : 28291166     DOI : https://doi.org/10.36452/jmedscientiae
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya. Tim editorial menerima naskah berupa artikel penelitian, literature dan systematic review, dan laporan kasus. Naskah yang dikirimkan hendaknya belum pernah diterbitkan sebelumnya di jurnal maupun media yang lain dan disiapkan sesuai dengan template atau format yang telah ditentukan. Setiap naskah yang memenuhi kriteria jurnal akan direview oleh pakar yang sesuai (peer reviewer). Jurnal MedScientiae tidak mengenakan biaya selama proses mulai dari penerimaan naskah hingga publikasi. Jurnal MedScientiae terbit 3 kali dalam satu tahun, yaitu pada bulan April, Agustus dan Desember dengan cakupan keilmuan yang telah disebutkan di atas. Edisi pertama jurnal akan diterbikan di bulan Mei tahun 2022 dengan nomor ISSN 2829-1166.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 18 Documents
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Search results for , issue "Vol. 3 No. 1 (2024): April" : 18 Documents clear
A Overview of the 2023 FKIK UKRIDA Study Program Students Breakfast Menu Variations Kurniawan, Inge; Winaktu, Gracia JMT; Susanto, Lucianana Budi; Hartanto, Hartanto
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3107

Abstract

The Balanced Nutrition Guidelines (PGS) presented by the Indonesian Ministry of Health in 2014 have a message, one of which is to get used to breakfast. Breakfast is an eating and drinking activity carried out between waking up and 9 am with the aim of meeting daily nutritional needs (15-30%). This research aims to get an overview of the variations in the breakfast menu of FKIK UKRIDA students. This research used a cross sectional descriptive design, taking subjects using purposive sampling. Data collection was carried out in October 2023. The research subjects consisted of 45 students who met the inclusion and exclusion criteria. The inclusion criteria are the 2020-2021 class who are aged 19-25 years and who eat breakfast. The results of this study showed that most of the subjects were female, namely 32 people (71.1%). Most of the subjects did not live with their parents/boarding house 27 (60%) with monthly pocket money mostly Rp. 1,000,000 – Rp. 2,500,000, namely 23 people (51.1%). Most of the subjects had normal weight nutritional status, namely 26 people (40%). The description of the subject's breakfast menu is quite varied, namely bread 14 (31.1%), fried chicken rice 11 (24.4%), and others 20 (42.1%), drinks namely water 22 (48.9%) , water and milk 5 (11.1%), and others 18 (37.8%).
E Efektivitas Albendazol Dosis Tunggal terhadap Infeksi Soil Transmitted Helminths (STH) Sari, Monica Puspa
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3110

Abstract

The problems of worm’s infection is still a problem for Indonesian people, especially children who live in endemic areas with a lack of sanitation and clean water. The two recommended treatment regiments are Albendazole 400 mg and Mebendazole 500 mg. Several studies report that the efficacy of albendazole varies. The aims of literature review is to assess the efficacy of albendazole against STH infections, and the factors that influence the efficacy of albendazole, factors that can increase efficacy and reduce efficacy. The research method used is a literature review with a descriptive approach based on literature from relevant research articles or journals. Library searches were searched via Google scholar, Pubmed, E-journal. The keywords and boolean operators used in the research are albendazole AND Soil transmitted helminths OR cure rate OR egg reduction rate. The CR of a single dose of albendazole against A. lumbricoides reaches 80-100%. 50-54% of hookworm infections occur due to frequent recurrent infections. There were differences in results regarding the CR of T. trichiura 12,8%-66,7% and 80-90%. This difference occurs due to differences in the degree of unfections. Single dose albendazole base on CR and ERR is less effective against T. trichiura infection. Albendazole should be given in combination with other drugs or in extra doses to eliminate STH infections.
Peran Vitamin D Dalam Menurunkan Risiko Penyakit Kardiovaskular Lim, Audi; Arsita, Elli
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3138

Abstract

Cardiovascular disease is the main cause of death in the world. Vitamin D is known to have an influence on the cardiovascular system through the role of the vitamin D receptor (VDR) expressed by vascular endothelial smooth muscle cells and cardiomyocytes. This literature review analyze the role of vitamin D in relation to the risk of cardiovascular disease through a study of scientific articles from Google Scholar and Pubmed. The results showed that patients with severe vitamin D deficiency (serum 25(OH) levels <10 ng/ml) had an increased risk of myocardial infarction with OR 4.5 (95% CI 2.2–9.2), and increased risk of PAD with OR 3.872 (95% CI: 1.168–12.841), while vitamin D deficiency (serum 25(OH) levels <20 ng/ml) caused an increased risk of acute ischemic stroke with OR 16.64 (95% CI: 5 .66–42.92; p < 0.001). Administration of 1x 600,000IU or 2x300,000IU intramuscular vitamin D in coronary heart disease patients with deficiency showed significant reduction in the inflammatory marker hsCRP and improved endothelial function. However, in clinical trials, significant but inconsistent results were obtained due to differences in the cut off value for Vit D deficiency, diversity in age, gender, variations in polymorphisms, smoking habits, physical activity, body weight, and various comorbidities suffered by patients.
Perbandingan Efektivitas Injeksi Agen-Agen Anti-Vegf pada Pengobatan Age-Related Macular Degeneration Nahak, Petronela Bhoko; Arsita, Elli; Wastitiamurti, Ritsia Anindita
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3143

Abstract

Age-related macular degeneration (AMD) is one of the leading causes of blindness in people >60 years of age in developed countries. The pathogenesis of neovascular AMD involves increased choroidal vascular permeability, leading to hypoxia and the production of pro-inflammatory and pro-angiogenic factors, particularly vascular endothelial growth factor (VEGF). Treatment of neovascular AMD involves anti-VEGF therapy, which inhibits abnormal blood vessel growth. Numerous studies have demonstrated the effectivity and side effects of each Anti-VEGF agent. Based on this background, the author is interested in conducting a literature review that summarizes the effectivity and side effects of each Anti-VEGF agent. The method used was Literature Review. Journals were collected using GoogleScholar or Google Scholar, PubMed and Proquest within the last 10 years. A total of 10 journals that met the inclusion-exclusion criteria were reviewed and tested for eligibility with the Ottawa score. The results of this literature review showed that anti-VEGF agents including bevacizumab, ranibizumab, aflibercept, pegaptanib sodium, brolucizumab and abicipar pegol have been shown to be equally effective in improving vision and maintaining stable vision in neovascular AMD patients. However, these anti-VEGF treatments can also cause side effects such as intraocular inflammation, increased intraocular pressure and vascular problems.
Pengaruh Pemberian Steroid Topikal Terhadap Tekanan Intra Okular : Sebuah Tinjauan Pustaka Lauw, Jessica Amelia; Muthia, Annisa Sri Rachma; Pangaribuan, Beatric Ruth Fransiska; Anugrahsari, Santi
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3162

Abstract

The use of topical corticosteroids, especially in the periocular area, has been associated with increased intraocular pressure (IOP), potentially leading to glaucoma and other eye complications. This study evaluated the risk of IOP elevation due to topical corticosteroid use and its influencing factors. This study is a literature review investigating the relationship between topical corticosteroid use and IOP elevation. Data were collected from studies reporting the effect of topical corticosteroids on IOP, including the type of steroid, duration of use, frequency of administration, and patient age. The findings suggest that the use of topical corticosteroids can lead to a significant increase in IOP, with the risk varying depending on the type of steroid, duration, and frequency of use, as well as individual patient characteristics such as age. Although some studies showed a significant increase in risk, other results showed minimal risk, suggesting the need for close monitoring of IOP in patients using topical corticosteroids. The use of topical corticosteroids in the periocular area requires careful consideration of the potential risk of increased IOP. It is important to choose steroids with low anti-inflammatory potential and monitor IOP regularly to reduce the risk of IOP-related side effects. Further studies are needed to fully understand the risks associated with using periocular topical corticosteroids and develop guidelines for safe use.
Tinjauan Pustaka Penggunaan Gawai dengan Kejadian Miopia Anugrahsari, Santi; Nugraha, Abraham William; Septrilla, Gladys; Veronica Agrippina
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3164

Abstract

Lifestyle changes during the pandemic has impacted the lives of almost every human being in the world. This lifestyle changes, especially the increase in the duration and frequency of gadget use for everyday routine can cause various unwanted side effects such as refractive disorders, especially myopia. This study aims to evaluate the correlation between gadget use and myopia and other relevant ocular biometric parameters such as axial length (AL) and spherical equivalent (SE). The literatures used in this study is taken from an electronic database using NCBI, ProQuest and Google Scholar with English keywords “Gadget”, “Myopia”, and “Vision Impairment” and in Indonesian “Gawai”, “Miopi”, dan “Kelainan Refraksi ”. The articles found was published between January 2012 and Juni 2022, which was then sorted according to the objective of this study and we found fifteen journals that we include in this study. The distance in which gadgets were used was found to have a correlation with myopia. Laying down while using gadgets was also found to be correlated with myopia. Meanwhile, the duration of gadget use has not been found to be correlated with myopia. Gadget use can be one of the risk factors for refractive disorders. Based on the literature we collected, it was found that gadget use distance less than 30 cm and laying down while using gadgets has a correlation with refractive disorders meanwhile the duration of gadget use was found to not be correlated with refractive disorders.
Prevalensi Kista Ovarium Di RS Swasta di Jakarta Barat pada tahun 2017-2021 Lauw, Jessica Amelia; Christina, Shintia; Pasaribu, Donna Mesina
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3189

Abstract

Ovarian cysts are generally divided into functional cysts, endometriosis, and neoplasm cysts with benign, borderline and malignant properties. Ovarian cysts occur in 82% of women of productive age. In general, ovarian cysts found are benign and the rest are a journey to malignancy. Detailed prevalence rates regarding ovarian cysts for each type of ovarian cyst have not been found in Indonesia, especially at Hermina Daan Mogot Hospital This type of research is descriptive, using a cross sectional design. This research was carried out at Hermina Daan Mogot Hospital from 2017 – 2021.From the results obtained, the most histopathological diagnosis was endometriosis with a total of 117 subjects (45.5%). The largest age group is 36.7 – 45.6 years old with 96 subjects and the least age category is ≥ 65.7 years old with 8 subjects. The most common type of ovarian cyst is endometriosis. The highest age range is 36.7 – 45.6 years.
Literature Review Exposure To Electric Cigarette Smoke (Vape) On Cerebrum And Rat Behavior Woen, Aurelia Wirasdita; Sumbayak, Erma Mexcorry
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3209

Abstract

E-cigarettes are a modern form of conventional cigarettes, many have used them because they contain nicotine and various flavors so that young people like them. This literature aims to determine the effects of exposure to e-cigarettes containing nicotine or not on the cerebrum and behavior of experimental animals. The method of making literature in the form of literature review with a comprehensive approach. By searching for articles or journals in research journal databases, internet, articles. The database search used was Google Scholar, Pubmed, Proquest. Exposure to e-cigarette smoke can cause damage to the cerebrum, such as inflammation to necrosis, besides it can cause decreased cognitive abilities, behavior to emotional. E-cigarettes contain various components that are dangerous if consumed for a long time can cause dependence, decreased cognitive memory function and emotional changes. Exposure to secondhand smoke also causes inflammation, damage or necrosis. Nicotine also plays a role in this.

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