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Inovasi Kesehatan Global
Published by Lembaga Pengembangan Kinerja Dosen
ISSN : 30464706     EISSN : 30464625     DOI : 10.62383
Core Subject : Health,
Medicine & Pharmacology Nursing Public Health
Inovasi Kesehatan Global, dengan e-ISSN : 3046-4625, p-ISSN : 3046-4706. Inovasi Kesehatan Global ini menyajikan hasil penelitian dan tinjauan pustaka sehingga jurnal ini bermanfaat bagi tenaga ahli kesehatan, apoteker, dokter dan perawat, pengambil kebijakan, tenaga kesehatan, dosen serta mahasiswa yang tertarik dengan publikasi ilmiah terkait Ilmu ilmu Farmasi dan Kesehatan. Jurnal ini terbit 1 tahun 4 kali (Februari, Mei, Agustus, dan November).
Arjuna Subject : Profesi Kesehatan - Menejmen Informasi Kesehatan
Articles 211 Documents
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Pengaruh Pemberian Obat Psikotropika terhadap Perilaku Swimming dan Floating pada Mencit (mus musculus) dalam Forced Swimming Test Haryanto Haryanto; Febriyanti Aswinda; Safira Nur Amalia; Rizka Salzabila J; Fitri Fitri; Muh. Rifkyansyah; Musdalifa Musdalifa
Inovasi Kesehatan Global Vol. 2 No. 3 (2025): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i3.2186

Abstract

This study explores the use of psychotropic substances, which affect the central nervous system and can alter mental functions, behavior, and individual perception. In the medical context, psychotropics have been widely utilized for treating mental disorders such as depression, anxiety, and schizophrenia. The research emphasizes the importance of understanding the mechanisms of psychotropics to optimize their therapeutic benefits while minimizing the risk of adverse effects. The study employed animal models, specifically rats, using the forced swimming test (FST) to assess the antidepressant and sedative effects of various substances, including Esilgan, Xanax, Zolmia, Syzygium malaccense leaf extract, and lelap (herbal), with NaCMC as a negative control. The results demonstrated varying sedative and antidepressant effects among the substances, with Xanax exhibiting the most significant antidepressant effect, while Syzygium malaccense leaf extract showed potential as a natural sedative agent. The study also underscores the importance of applying the 3R ethical principles (Replacement, Reduction, Refinement) in animal research and highlights the need for alternative methods to reduce reliance on animal testing. These findings are expected to serve as a foundation for developing safer, more effective, and ethical psychotropic therapies for mental disorders in the future.
Penatalaksanaan Fisioterapi Pada Kasus Fraktur Radius Dan Supracondyeler Stifness Joint: Case Report Sabrina Tristiana Abkhoir; Arif Pristianto; Warih Sri Widodo
Inovasi Kesehatan Global Vol. 2 No. 3 (2025): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i3.2196

Abstract

Radius fracture and supracondylar joint stiffness are common post-traumatic complications that can reduce upper extremity function and limit daily activities. These problems are generally accompanied by pain, decreased range of motion (LGS), and muscle strength, thus disrupting the patient's functional independence. This study aims to evaluate the effectiveness of multimodal physiotherapy interventions in improving the clinical condition of patients with post-ORIF radius fractures and supracondylar joint stiffness. This study is a case study of a 47-year-old male patient treated at Panembahan Senopati Bantul Regional Hospital. Physiotherapy interventions were carried out twice, with modalities consisting of infrared therapy, muscle release techniques, assisted active exercises, strengthening exercises, and hold-relax techniques. Clinical evaluation was carried out using the Numerical Rating Scale (NRS) for pain, Manual Muscle Testing (MMT) for muscle strength, goniometer for LGS, and Mayo Elbow Score for joint function. The results of the study showed a decrease in pain levels, an increase in LGS and muscle strength, and an improvement in daily activity function. The synthesis of these findings indicates that multimodal physiotherapy interventions have a positive clinical impact on postoperative joint stiffness and musculoskeletal disorders. In conclusion, a combination of various physiotherapy techniques is effective in addressing pain, mobility limitations, and functional impairment in patients with post-ORIF radius fractures and supracondylar joint stiffness, and underscores the importance of a comprehensive and individualized rehabilitation approach.
Penerapan Head Up 30̊ terhadap Penurunan Kapasitas Adaptif Intrakranial pada Pasien dengan Hidrosefalus Post VP Shunting di RSUD Dr. Moewardi Surakarta Erlena Nur Intan; Sri Puguh Kristiyawati
Inovasi Kesehatan Global Vol. 2 No. 3 (2025): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i3.2204

Abstract

Hydrocephalus increases cerebrospinal fluid due to either excessive production or impaired absorption, often accompanied by increased intracranial pressure. In Indonesia, hydrocephalus affects 10 out of every 1,000 newborns annually. In adolescents and adults, toxoplasmosis is the most common cause. Among infant cases, 46% result from brain development abnormalities, 50% from subarachnoid hemorrhage and meningitis, and less than 4% from posterior fossa tumors. Central Java reports the highest rate of toxoplasmosis at 10%. Common signs and symptoms of hydrocephalus include increased cerebrospinal fluid, seizures, irritability, headaches, vision problems, and head enlargement. To improve reduced intracranial adaptive capacity caused by cerebrospinal fluid obstruction, nurses can apply a 30° head-up therapy. This intervention helps lower intracranial pressure and improve brain oxygenation. the effectiveness of 30° head-up positioning in addressing decreased intracranial adaptive capacity in post-VP shunting hydrocephalus patients. The nursing intervention was implemented on Mrs. S using the 30° head-up position. As a result, the patient reported reduced headache, and her blood pressure decreased to 135/90 mmHg.
Case Report : Eritema Nodosum Leprosum pada Pasien Pasca Terapi Kusta Tipe MB dengan Kecacatan Tingkat 2 Mohamad Mimbar Topik; Mumtaz Alvira
Inovasi Kesehatan Global Vol. 2 No. 3 (2025): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i3.2206

Abstract

Erythema nodosum leprosum (ENL) is a type 2 leprosy reaction caused by the humoral immune response of Mycobacterium leprae, which results in inflammatory nodules on the skin that can lead to nerve and organ damage. One of the immune-mediated complications of leprosy and severe multisystem lepromatous leprosy is known as type 2 leprosy reaction or erythema nodusum leprosum (ENL). Risk factors for ENL can be influenced by age, educational attainment, socioeconomic status, and gender. ENL causes high morbidity and mortality and usually requires immediate medical attention. We report a case of ENL with grade 2 disability in a clinically diagnosed Multibacillary (MB) leprosy patient who had had leprosy for 20 years.
Analisis Penerapan Rekam Medis Elektronik di Puskesmas X Kota Semarang dengan Metode Hot-Fit Titi Santika; Faizatu Fithriah; Sofy Fara Yoha; Lilya Oktaviana Dewi; Edy Susena
Inovasi Kesehatan Global Vol. 2 No. 3 (2025): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i3.2207

Abstract

X Health Center has implemented EMR on SIMPUS since 2009-2010. However, from the preliminary study, it was found that there were obstacles such as network trouble, long loading when many users were pulling data on the system, and there was no SOP for down time: The purpose of this study is to analyze the implementation of Electronic Medical Records at X Health Center, Semarang City in the aspects of Human, Organization, Technology, Net-benefit. Methods: This study used a descriptive qualitative approach with interviews, observations and documentation studies. Results: The results of research at X Health Center show that there are problems in implementing EMR at X Health Center, in the human aspect, namely system training is still given only to representative officers such as IT and SIK staff. In the organizational aspect, namely limited facilities and lack of manpower. On the technology aspect, namely internet network instability, inconsistent electricity supply and generator unpreparedness and hardware limitations. While in the net-benefit aspect, the implementation of EMR has an impact on increasing the efficiency and effectiveness of X Health Center services. Conclusion: The implementation of electronic medical records at X Health Center is not yet fully optimal, namely in the aspects of human, organization and technology.
Kajian Stabilitas Fisikokimia Antibiotik β-laktam: Implikasi terhadap Formulasi dan Penyimpanan Abu Dzar Alghifary; Nor Latifah
Inovasi Kesehatan Global Vol. 2 No. 3 (2025): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i3.2215

Abstract

β-lactam antibiotics are a very important group of drugs and are most frequently used in the treatment of bacterial infections, both in healthcare facilities and for self-medication. The advantages of β-lactams lie in their effectiveness and broad spectrum of action. However, the development of pharmaceutical preparations containing β-lactams still faces significant challenges, particularly related to the physicochemical stability of these compounds. The reactive ring structure of β-lactams makes them highly susceptible to degradation, particularly through hydrolysis. This degradation process can be accelerated by various environmental factors such as high temperature, changes in pH, humidity, and the presence of certain excipients and solvents in drug formulations. This article comprehensively reviews the various factors that influence the stability of β-lactams, both in solid and liquid pharmaceutical dosage forms, as well as in microbiological media. Furthermore, it also examines various innovative formulation approaches that have been developed to improve the stability of these compounds. These approaches include film coating technology, encapsulation, and crystal engineering, which have been shown to reduce the rate of degradation and extend product shelf life. Literature studies have shown that solid dosage forms are generally more stable than liquid dosage forms, primarily because exposure to water and solvents can accelerate hydrolysis. Distribution and storage of these preparations are also important aspects to consider in maintaining the quality and effectiveness of β-lactam antibiotic therapy. Therefore, β-lactam product development requires a holistic approach, encompassing not only formulation and production technology but also optimal distribution and storage strategies. The use of appropriate analytical methods is also necessary to monitor degradation products and ensure product safety and effectiveness throughout the shelf life.
Isolasi dan Identifikasi Senyawa Metabolit Sekunder Ekstrak Daun Kopi Arabika (Coffea arabica) Menggunakan Teknik Kromatografi Nurul Amaliya Hikma; A. Nur Afiah Rahman; Siti Aisyah Basir; A. Yeyen Maharani; Pingki Pingki; A. Putri Wulandari Syam; Mufidah Humairah S; Nur Andini; Fatma Fatma; Fityatun Usman
Inovasi Kesehatan Global Vol. 2 No. 3 (2025): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i3.2216

Abstract

This study aims to extract and purify secondary metabolite compounds from Coffea arabica leaves using various separation techniques, such as maceration, column chromatography, thin layer chromatography (KLT), and preparatory KLT, and followed by flavonoid content analysis using UV-Vis spectrophotometry. The process begins with drying the arabica coffee leaves, then extraction is carried out using 96% ethanol for three days. After that, the solvent is evaporated with a rotary evaporator at 60°C to obtain a viscous extract. The extracts were further separated using column chromatography with a mixed solvent of n-hexane: ethyl acetate (3:1), resulting in 12 fractions that showed color differences, which was an indication of the diversity of the compounds in the extract. Advanced identification was carried out with KLT using methanol solvents: chloroform (9:1) at UV wavelengths of 254 nm and 366 nm, indicating the presence of compounds with medium to high polarity. Furthermore, the isolated compounds were further separated using the preparative KLT (KLTP) method. To determine the flavonoid content, UV-Vis spectrophotometry was performed at a wavelength of 431 nm, using quercetin as standard. The results of the analysis showed that Arabica coffee leaf extract had a yield of 7.35% and a total flavonoid content of 19.0605 mgQE/g. These findings show that arabica coffee leaves are a source of flavonoid compounds that have the potential for the development of herbal or phytopharmaceutical products. The flavonoid content found may provide health benefits, particularly in increasing antioxidant activity, which can be used in the treatment of oxidative stress-related diseases. The results of this study also open up opportunities for the development of plant-based products, especially Arabica coffee, in the pharmaceutical and cosmetic industries as an efficacious natural active ingredient.
Upaya Penanganan Pasien Skabies Usia 23 Bulan Melalui Pendekatan Kedokteran Keluarga di Puskesmas Simpang Keuramat Danisa Indira Fatma; Noviana Zara
Inovasi Kesehatan Global Vol. 2 No. 3 (2025): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i3.2219

Abstract

A 23-month-old female patient presented with red, itchy bumps, accompanied by intense itching, which caused the skin to peel from scratching. These symptoms began less than a month before the visit and worsened one week before seeking treatment. The fluid-filled bumps burst due to scratching, causing sores and peeling skin. The itching was constant and tended to worsen at night. The use of moisturizer by the patient's mother provided little relief. The onset of these symptoms coincided with a visit from the patient's mother's younger brother, a student at the Islamic boarding school (Santri), who was staying at the patient's home during the holidays. Less than a month later, similar symptoms began to be felt by the patient, her siblings, and both parents. The diagnosis was based on primary data obtained through a history taking with the patient's mother, a direct physical examination during a home visit, and completion of the family file and the patient's medical records. The patient, suspected of having scabies, was treated with 5% permethrin cream, applied as directed, and cetirizine to reduce the itching. Case assessments are conducted holistically, assessing the initial condition, process, and final outcome of each visit both quantitatively and qualitatively. Interventions include not only treatment but also comprehensive family education. This education includes an explanation of the etiology and transmission of scabies, the importance of maintaining personal and environmental hygiene, and potential complications such as secondary skin infections due to scratching. The goal of this education is to improve patient and family compliance with therapy, prevent reinfection, and break the chain of disease transmission in the home environment. This approach is expected to not only reassure the patient but also raise family awareness of the importance of clean and healthy living practices as a long-term preventative measure.
Analisis Faktor-Faktor yang Mempengaruhi Tingkat Kesadaran Masyarakat tentang Kesehatan Lingkungan di Kota Medan Syahrul'an Syahrul'an; Nur Laily Harfita
Inovasi Kesehatan Global Vol. 2 No. 3 (2025): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i3.2221

Abstract

Awareness of environmental health is an important factor in maintaining community welfare, especially in developing urban areas. The city of Medan, as one of the major cities in Indonesia, still faces various environmental problems such as poor sanitation, garbage accumulation, and water pollution, which have an impact on public health. This study aims to analyze the factors that affect the level of public awareness of environmental health in the city of Medan. This study uses a quantitative design with a cross-sectional approach. Data were collected from 100 randomly selected respondents using a structured questionnaire, which measures people's level of awareness of environmental health and various factors that influence it, such as education level, media exposure, and economic status. Data analysis was carried out univariately, bivariately with Chi-square test, and multivariate using logistic regression to determine the relationship between independent variables and the level of public awareness. The results of the study show that factors such as education level, media exposure, and economic status have a significant influence on the level of public awareness. People with higher levels of education, better media exposure, and better economic status tend to have higher awareness of environmental health issues. The implications of these findings suggest that improving environmental education and more effective dissemination of information can be an important effort in raising public awareness. Community-based programs that focus on education and strengthening environmental information can be a strategic step in overcoming environmental problems in urban areas. The results of this research are expected to be a reference for the formulation of more effective policies and programs in increasing environmental awareness in urban communities.
Silikotuberkulosis : Kombinasi Penyakit Paru Akibat Paparan Silika yang Meningkatkan Risiko Tuberkulosis pada Pekerja Berisiko Muthia Verza Mardhiyah; Ikhsan Ikhsan
Inovasi Kesehatan Global Vol. 2 No. 3 (2025): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i3.2226

Abstract

Silicotuberculosis is a complex lung disease, a combination of silicosis and tuberculosis (TB). Silicosis is a disease caused by the inhalation of silica particles, which can lead to pulmonary fibrosis, while TB is an infectious disease caused by Mycobacterium tuberculosis. Long-term exposure to silica dust can cause silicosis and also increase the risk of TB infection, especially in countries with a high TB burden. Workers exposed to silica dust in the mining, construction, and manufacturing industries are among the groups most at risk. The diagnosis of silicotuberculosis is often difficult because the clinical and radiological symptoms of the two diseases often overlap. Symptoms, such as chronic cough, shortness of breath, and chest pain, can be very similar in silicosis and TB, often delaying a correct diagnosis. The pathophysiology of silicotuberculosis involves impaired function of macrophages, immune cells that play a role in fighting infection, and a compromised immune response due to silica exposure. These disruptions facilitate the progression of TB infection, further worsening the patient's health. Primary management of silicotuberculosis includes controlling TB infection with standard anti-tuberculosis drug therapy (OTT) and preventing silica exposure. Preventing occupational exposure to silica dust is crucial to reducing the risk of developing the disease. The prognosis of the disease is greatly influenced by the severity of pulmonary fibrosis and delay in diagnosis. The more severe the fibrosis, the worse the prognosis. Therefore, preventing silica dust exposure, along with routine TB screening for high-risk workers, is crucial to reducing the incidence of silicotuberculosis. Furthermore, education about the risks of the disease is crucial to raise awareness among workers and the general public.

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