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Mohammad Rizki Fadhil Pratama
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Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya Building B 1st Floor, RTA Milono St. Km.1,5. Palangka Raya 73111, INDONESIA
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Borneo Journal of Pharmacy
Published by Universitas Muhammadiyah Palangkaraya
ISSN : -     EISSN : 26214814     DOI : https://doi.org/10.33084/bjop
Core Subject : Health,
Medicine & Pharmacology
Borneo Journal of Pharmacy publishes various scientific articles covering Pharmacy and Pharmaceutical Sciences in the field but not limited to: Pharmacology-Toxicology, including pharmacokinetics, pharmacodynamics, pharmacotherapy, and toxicology. Pharmacognosy-Phytochemistry, including pharmacognosy, phytochemistry, ethnobotany, and ethnopharmacology. Pharmaceuticals, including biopharmaceuticals, pharmaceutical technology, formulations, and biotechnology. Analytical Pharmacy-Medicinal Chemistry, including pharmaceutical chemistry, chemical analysis, medicinal chemistry, bioinformatics, pharmacy physics, pharmaceutical analysis, and method validation. Microbiology Pharmacy, including the antibacterial, antifungal, and antiviral activity test. Natural Product Development, including testing the pharmacological activity of extracts, fractions, and plant isolates. Clinical-Community Pharmacy, including monitoring usage, side effects, counseling, and drug use evaluation. Management Pharmacy, including drug management, drug use profiles, pharmaceutical administration, and marketing.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 300 Documents
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In the Footsteps of Scribonius Largus, a Pioneer of Clinical Pharmacy in Ancient Rome Christos Tsagkaris; Anna Loudovikou; Dimitrios V. Moysidis; Andreas S. Papazoglou; Konstantinos Kalachanis
Borneo Journal of Pharmacy Vol. 4 No. 3 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i3.2360

Abstract

Clinical pharmacy involves pharmacists in direct patient care concerning optimizing medicines and promoting health awareness and disease prevention. The whereabouts of the field can be traced to Scribonius Largus, a renowned physician and pharmacist in ancient Rome. Although Largus served as an imperial physician, he has also been an exemplary pharmacist authoring a comprehensive pharmacognosy textbook and dedicated a big part of his life to improving pharmacotherapy and advancing ethics in the field. Revisiting his contributions provides valuable lessons for contemporary clinical pharmacists.
Pharmacological screening of Eryngium foetidum Linn – A Review Galamula Hewage Tharuka Kanchana Hemachandra; Sinnadurai Thuvaragan; Vinotha Sanmugarajah
Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i4.2377

Abstract

Eryngium foetidum L. (Family Apiaceae) is a biennial herb, and it is used as a culinary herb and spice across the different countries of the world, including Sri Lanka, India, Bangladesh, Malaysia, Singapore, etc. due to its high aroma quality. Also, it is used to treat several ailments, such as respiratory diseases, gastrointestinal ailments, and skin diseases among different indigenous populations for its medicinal properties. Based on ethnomedical evidence, many studies have been conducted to identify the phytoconstituents, underlying mechanisms, and related pharmacological effects of different parts of this plant. This study reviewed the current state of findings related to the Pharmacological activities of E. foetidum. Based on this review, this plant is widely used for ethnomedical and culinary purposes. Pharmacological screening of the plant revealed that it had different activities such as anti-inflammatory, antioxidant, antimicrobial, anthelminthic, anticonvulsant, anticancer, antidiabetic, antimalarial, larvicidal, and hepatoprotective activities. This review further promised that potential new chemical entities could be elicited from the phytoconstituents of E. foetidum.
Traditional Turkish Coffee with Medicinal Effect Senthil Rethinam; Serdar Batıkan Kavukcu; Hayati Türkmen; Arife Candaş Adıgüzel Zengin; İhsan Yaşa
Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i4.2378

Abstract

Traditional Turkish coffee (TTC) is highly associated with caffeine and is known as a mind and heart stimulant as it helps keep tiredness at bay. Daily consumption of TTC naturally benefits human health such as anti-cancer, anti-diabetic, improved energy, anti-depression, reduced risk of heart disease, etc. The TTC was derived from particular types of Arabic coffee beans (ACB), and the preparation method of TTC is unique from other types of coffee. The main objective of the study was to investigate the therapeutic and biological effects of TTC. The ACB powder was characterized physicochemically using UV-Vis spectroscopy, Fourier transforms infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX). In vitro analysis using HaCaT (Human keratinocyte cell line) proved the biocompatibility of ACB powder. Case studies which were focusing on healthy individuals as the research populace were conducted using TTC. Consumption of TTC was found beneficially compared to other types of coffee. The TTC was obtained from ACB, which was characterized by spectroscopic techniques and displayed biocompatibility due to the results on HaCaT cell lines. The TTC has beneficial therapeutic effects on individuals. According to statistical analysis, the disease-affected ratio of diabetes, heart disease, and depression was significantly decreased.
Effectiveness of Oxalis corniculata L. Ethanol Extract against Mono-Species of Biofilm Staphylococcus aureus Hasyrul Hamzah; Khalish Arsy Al Khairy Siregar; Ari Nurwijayanto; Retno Wahyuningrum; Seftika Sari
Borneo Journal of Pharmacy Vol. 4 No. 3 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i3.2418

Abstract

Inappropriate administration of antibiotics can cause resistance to bacteria. Staphylococcus aureus is one of the strong biofilm-forming bacteria that cause antibiotic resistance. Calincing (Oxalis corniculata L.) leaves have excellent antibacterial activity, but their antibiofilm activity against S. aureus has not been reported until now. Currently, the discovery of new antibiofilm against S. aureus biofilms is significant to prevent the impact of infections caused by biofilms. This study was intended to determine the effectiveness of the ethanol extract of O. corniculata leaves in inhibiting and eradicating S. aureus biofilm formation. Planktonic testing, inhibition, and biofilm eradication activity were carried out using the microtiter broth method. Antibiofilm activity of O. corniculata leaves against S. aureus biofilm was analyzed by calculating the minimum concentration of biofilm inhibitor (MBIC50) and minimum biofilm eradication concentration (MBEC50). Data were analyzed using the Statistical Package for the Social Sciences (SPSS) with a 95% confidence level. Oxalis corniculata leaves showed inhibitory activity on the formation of the tested S. aureus biofilm. The ethanol extract of 1% O. corniculata leaves gave 76.23±0.01% antibacterial activity of S. aureus and 71.32±0.01% of mid-phase antibiofilm activity, and 69.33±0.01% maturation phase. The results also prove that the ethanolic extract of O. corniculata leaves can eradicate S. aureus biofilm formation. Therefore, the ethanol extract of O. corniculata leaves can be developed as a new antibiofilm against S. aureus.
Correlation Analysis of Antioxidant Activities with Tannin, Total Flavonoid, and Total Phenolic Contents of Nutmeg (Myristica fragrans Houtt) Fruit Precipitated by Egg white Irma Antasionasti; Olvie Syenni Datu; Utami Sasmita Lestari; Surya Sumantri Abdullah; Imam Jayanto
Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i4.2497

Abstract

The nutmeg (Myristica fragrans) flesh extract has a strong antioxidant activity. Therefore, M. fragrans flesh can be developed for functional drinks which are sources rich in antioxidants good for the prevention and treatment of diseases such as cancer and cardiovascular diseases. However, the tannins' content can cause a bitter and sour taste. Therefore, the tannins content should be reduced by the addition of egg white. The purpose of this study is to find out the comparison of antioxidant activity between a combination of M. fragrans flesh extract with various concentrations of egg white and to correlate its antioxidant activities with tannin, total flavonoid, and total phenolic contents. The antioxidant activities were conducted on M. fragrans flesh extract by using DPPH and ABTS radicals. Tannin, total flavonoid, and total phenolic contents from M. fragrans flesh extract were also tested. The M. fragrans flesh extracts without addition egg white have a strong antioxidant in scavenging the stable free radical ABTS (89.980±0.480 µg/mL) and intermediate antioxidant in scavenging the stable free radical DPPH (105.669±0.102 µg/mL). It is followed accordingly by tannin, total flavonoid, and total phenolic contents, namely 14.034±0.100 %w/w TAE, 26.929±0.129 %w/w QE, and 53.164±0.129 %w/w GAE, respectively. Correlation of tannin, total flavonoid, and total phenolic contents, which inhibited DPPH and ABTS radicals had R2 values of about 89.23-97.63%. It showed that antioxidant activity is strongly influenced by the tannin, total flavonoid, and total phenolic contents. Therefore, precipitation from the tannin-protein bond caused antioxidant activities were decreased.
Immunity-Boosting Natural Herbs to Combat COVID-19 Pandemic: A Narrative Review Saurabh Nimesh; Muhammad Akram; Md. Iftekhar Ahmad; Arshad Ahmad; Pratibha Kumari; Manohar Lal
Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i4.2534

Abstract

Coronaviruses cause some severe forms of respiratory infections such as Severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and Coronavirus disease 2019 (Covid-19). These viruses cause diarrhea in pigs and cows and upper respiratory disease in chickens, while other symptoms may differ. In humans, a total of six coronaviruses have been identified HCoVs-NL63, HCoVs-OC43, HCoVs-229E, HCoVs-HKU1, MERS-CoV, and SARS-CoV. The world health organization (WHO) has done a great deal of hard work regarding combating the monstrous effects of this virus. So far, no specific antiviral drugs have been developed for the treatment of Covid-19. Therefore, the medicinal plants used for the previous epidemic outbreaks are getting attention for their potential treatment against the virus. It has been reported that 70 to 80% of people in developing countries depend on medicinal plants or phytomedicine compared to allopathic drugs for their primary healthcare. The south Asian subcontinents have used almost up to 25,000 formulations and extracts obtained from medicinal plants for treatment in folk medicine. The present review discusses an overview of the coronavirus, its immune responses, and some immunity-boosting herbs to combat Covid-19.
Compressional Physics of Binary Mixture of Dried Andrographis paniculata and Moringa oleifera Leaves Johnson Ajeh Isaac; Kokonne Elizabeth Ekere; Ekeh Ezekiel; Isa Hayatu Galadima; Rashida Abdulahi; Ayuba Samali
Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i4.2544

Abstract

Traditionally, the leafy part of Andrographis paniculata and Moringa oleifera have been widely reported to manage hypertension. Investigation of its pharmacological actions justifies its use. As part of formulation studies to standardize them, this study focused on their compaction and compression properties. Compacts equivalent to 250 mg of A. paniculata and M. oleifera were produced by compressing powders and granules at various compression pressure. Results show that M. oleifera met the WHO limit for ash values. Relative density values for granulated batches were higher, while their moisture content values were lower when compared to those of direct compression. The result from Heckel plots shows that batches deform mainly by plastic flow. For Kawakita plots, values of 1/b show that batches containing microcrystalline cellulose were less cohesive. The plot of tensile strength signifies that granulated batches achieved maximum crushing strength faster at low pressure. Formulations containing maize starch were shown to have higher percent porosity, and granulated batches gave higher values for apparent density-pressure relationship and lower friability values. Tablets produced by the wet granulation method showed better compression and compaction properties than those formulated by direct compression.
Microbes, Clinical trials, Drug Discovery, and Vaccine Development: The Current Perspectives Venkataramana Kandi; Tarun Kumar Suvvari; Sabitha Vadakedath; Vikram Godishala
Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i4.2571

Abstract

Because of the frequent emergence of novel microbial species and the re-emergence of genetic variants of hitherto known microbes, the global healthcare system, and human health has been thrown into jeopardy. Also, certain microbes that possess the ability to develop multi-drug resistance (MDR) have limited the treatment options in cases of serious infections, and increased hospital and treatment costs, and associated morbidity and mortality. The recent discovery of the novel Coronavirus (n-CoV), the Severe Acute Respiratory Syndrome CoV-2 (SARS-CoV-2) that is causing the CoV Disease-19 (COVID-19) has resulted in severe morbidity and mortality throughout the world affecting normal human lives. The major concern with the current pandemic is the non-availability of specific drugs and an incomplete understanding of the pathobiology of the virus. It is therefore important for pharmaceutical establishments to envisage the discovery of therapeutic interventions and potential vaccines against the novel and MDR microbes. Therefore, this review is attempted to update and explore the current perspectives in microbes, clinical research, drug discovery, and vaccine development to effectively combat the emerging novel and re-emerging genetic variants of microbes.
Peel-off Kefir Mask Arachi (Arachis hypogaea L.): Characterization and Antioxidant Activity Amalia Khairunnisa; Pratika Viogenta; Nani Kartinah; Fathur Rahman; Mulia Mulia
Borneo Journal of Pharmacy Vol. 5 No. 1 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i1.2597

Abstract

This study aims to determine the best formulation for the peel-off mask Arachi or peanut (Arachis hypogaea L). Arachis hypogaea kefir as an active ingredient is added with variations in the concentration of F1 (0.5%) and F2 (2%) (w/v). Organoleptic tests, homogeneity, dry time, and pH were carried out on the peel-off mask that had been made. Antioxidant test (DPPH methods) was performed on masks F1 and F2. The results showed that the peel-off mask of A. hypogaea kefir had the best antioxidant activity at a concentration of 2% (F2) kefir with an IC50 value of 1.865 ppm and was very active. The characteristics of the peel-off mask have good physical stability, proven by not experiencing a change in color, odor, being homogeneous, having good dispersion power, and having a dry time ranging from 10-23 minutes. The pH value of the peel-off mask preparation is 4.52, and it is appropriate with SNI and the pH balance of normal human skin. The peel-off mask of A. hypogaea kefir can be produced because has good physical stability and antioxidant activity.
Control of the Nanoparticles Content in Cosmetic Medicines Marina Viktorivna Rakhimova; Igor Nikolaevich Bondarenko; Oleg Grigorovitsh Avrunin; Andrii I. Fedosov; Irina A. Sych; Vitaliy Dmitrievich Yaremenko; Olha O. Vislous; Lina O. Perekhoda
Borneo Journal of Pharmacy Vol. 5 No. 1 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i1.2708

Abstract

The safety of nanoparticles used in medical cosmetology and dermatology raises significant concerns. One of the tasks of analyzing the concentration of nanoparticles that must be solved for the practical analysis of the quality of products with nanoparticles is the quantitative analysis of the content of nanoparticles. The previously developed acousto-magnetic method (AMM) for determining the concentration of APIs as magnetic nanoparticles can be used to determine the nanoparticles' concentration when samples are prepared as a colloidal solution. It is shown that the described method not only can be applied for quality control in cosmetology and dermatology but also can be simplified by using a less sensitive magnetometer, which makes this direct method more available in the entire range of values ​​of the concentration of magnetic nanoparticles used in medical cosmetology and dermatology.

Page 13 of 30 | Total Record : 300

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