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Mohammad Rizki Fadhil Pratama
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mohammadrizkifadhilpratama@umpr.ac.id
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bjop@umpr.ac.id
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Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya Building B 1st Floor, RTA Milono St. Km.1,5. Palangka Raya 73111, INDONESIA
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Borneo Journal of Pharmacy
Published by Universitas Muhammadiyah Palangkaraya
ISSN : -     EISSN : 26214814     DOI : https://doi.org/10.33084/bjop
Core Subject : Health,
Medicine & Pharmacology
Borneo Journal of Pharmacy publishes various scientific articles covering Pharmacy and Pharmaceutical Sciences in the field but not limited to: Pharmacology-Toxicology, including pharmacokinetics, pharmacodynamics, pharmacotherapy, and toxicology. Pharmacognosy-Phytochemistry, including pharmacognosy, phytochemistry, ethnobotany, and ethnopharmacology. Pharmaceuticals, including biopharmaceuticals, pharmaceutical technology, formulations, and biotechnology. Analytical Pharmacy-Medicinal Chemistry, including pharmaceutical chemistry, chemical analysis, medicinal chemistry, bioinformatics, pharmacy physics, pharmaceutical analysis, and method validation. Microbiology Pharmacy, including the antibacterial, antifungal, and antiviral activity test. Natural Product Development, including testing the pharmacological activity of extracts, fractions, and plant isolates. Clinical-Community Pharmacy, including monitoring usage, side effects, counseling, and drug use evaluation. Management Pharmacy, including drug management, drug use profiles, pharmaceutical administration, and marketing.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 300 Documents
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Dyspepsia Drug Use Pattern of Outpatients in a Public Health Center in Batununggal District Bandung Linda Purnamawati Suherman; Pudjiastuti Kartidjo; Iis Rukmawati; Vina Septiani; Fazrin Azzura
Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i4.1987

Abstract

Dyspepsia is a condition of pain in the epigastrium and a burning sensation that radiates to the chest. Dyspepsia occupies the 10th position in the 20 largest non-communicable diseases in a Public Health Center in Bandung. The heterogeneous symptoms and the absence of specific treatments can lead to irrational treatment. The research objective is to determine the pattern of drug use in patients with dyspepsia, including the right indication, the proper drug selection, the correct dose, and the proper interval of administration in a Public Health Center in Batununggal District Bandung. This study was an observational study using a cross-sectional study design that was descriptive in nature. The sampling technique employed the purposive sampling method retrospectively. The research was conducted on 104 patients diagnosed with dyspepsia with comorbidities and receiving drugs at an Outpatient Clinic in a Public Health Center in Batununggal District Bandung from January-March 2020. There were 38 male patients (36.538%) and 66 female patients (63.462%). The majority of patients were aged 56-65 years (28.846%). The most used drug class was antacids (60.448%), and the dosage form that was mostly used was tablets (40.299%). The most used single drug was antacids (51.923%), while the most used drug combination was antacids and omeprazole (23.077%). The accuracy of drug selection and the accuracy of indications were 100% correct, the accuracy of the dosage was 59.62% correct, the accuracy of the time interval for drug administration was 71% correct, and the accuracy of the duration of drug administration was 9.62% correct.
Antisense Oligonucleotides: Concepts and Pharmaceutical Applications Ariana Araya; David Arias; Karla Coto; María Rebeca López; Joselyn Rivera; Juan José Mora
Borneo Journal of Pharmacy Vol. 6 No. 1 (2023): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v6i1.2092

Abstract

Antisense oligonucleotides are drugs whose mechanism is based on binding to RNA target sequences. For this purpose, they modify the protein expression through steric hindrance and exon omission. Its production involves several steps: synthesis, purification, and lyophilization. Usually, the most complicated procedure is synthesis due to the chemical reactions necessary to add the required oligonucleotide bases. BP1001, inotersen, nusinersen, eteplirsen, and golodirsen are a few antisense drugs developed for treating neurodegenerative and neuromuscular diseases. Although antisense oligonucleotides present off-target reactions, multiple studies are being performed. The following review shows information regarding the pharmaceutical characteristics for industrial production and the current state of applicability in clinical practice. In conclusion, some molecules have already been approved for commercialization (inotersen, nusinersen, ataluren, eteplirsen, and golodirsen), showing them as promising therapeutic solutions in the short and medium term for disorders developed by specific genetic factors.
Monoclonal Antibodies: A Therapeutic Option for the Treatment of Ophthalmic Diseases of the Eye Posterior Segment Catalina Ayón; Daniel Castán; Adrián Mora; Dunia Naranjo; Francini Obando; Juan José Mora
Borneo Journal of Pharmacy Vol. 5 No. 3 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i3.2095

Abstract

The eye is an organ that allows us to observe the outside world. Pathologies of the eye's posterior segment, such as glaucoma, macular degeneration, diabetic retinopathy, uveitis, and retinoblastoma, cause vision loss. Traditional treatments consist of applying topical medications that do not penetrate properly or using high doses that generate adverse effects. Different laser surgeries stop the pathology's progression but do not allow visual improvement. So, an alternative is to use monoclonal antibodies, proteins produced by different processes that selectively bind to metabolites associated with diseases, reducing the adverse effects of traditional treatments and improving the application of the drug in the area. The two main molecular targets are TNF (adalimumab, infliximab, and certolizumab pegol) and VEGF (bevacizumab and ranibizumab); other possibilities are under investigation.
Acute Toxicity of Self-Nanoemulsifying Drug Delivery System of Ipomoea reptans Poir Leaves Extract on Female Wistar Rats Cynthia Astiti Putri; Farida Hayati; Lutfi Chabib; Muhammad Iqbal Pangestu
Borneo Journal of Pharmacy Vol. 6 No. 1 (2023): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v6i1.2099

Abstract

Ipomoea reptans Poir has many health benefits, such as decreasing blood glucose and as an antioxidant. Self-nano emulsifying drug delivery systems (SNEDDS) are an innovation in pharmaceutical technology that minimizes drug molecules and maximizes surface area, thus increasing drug absorption. This study aimed to investigate SNEDDS of I. reptans acute toxicity in female Wistar rats. An acute toxicity test was done using a limit test of OECD 423. Female Wistar rats were divided into control and treatment groups, with three animals for each group being used per step. No animals died after they were given SNEDDS of I. reptans leaves extract at a dose of 2000 mg/kg. No toxic effect was detected at clinical examination and histopathology of the organ. SNEDDS of I. reptans leaves extract had an LD50 cut-off value of 5000 mg/kg.
Knowledge and Attitude of Antibiotic Use among Public in Rural Area of Cempaka, Banjarbaru, South Kalimantan Nurul Mardiati; Rahmayanti Fitriah; Nadia Wahyu Artati; Wika Tiarawati; Muhammad Zaini
Borneo Journal of Pharmacy Vol. 4 No. 3 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i3.2118

Abstract

The high intensity of antibiotics relatively uses causes various problems for health, especially bacterial resistance to antibiotics. Lack of public knowledge about the rationale of antibiotics is a factor that can trigger bacterial resistance to antibiotics. This study aims to assess the public's knowledge and attitudes towards antibiotic use in rural areas Cempaka, Banjarbaru, South Kalimantan. This was a descriptive cross-sectional survey method in which closed-ended questionnaires were distributed to 380 rural residents in the village of Cempaka proportional stratified random sampling technique. Data analysis used univariate and bivariate with the Chi-Square statistical test method. In conclusion, the rural residents demonstrated moderate knowledge (83.2%) and a positive attitude towards antibiotic use (97.4%). There is no significant association between both knowledge level and of antibiotics on the attitude towards antibiotic use.
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 4 No. 1 February 2021 Chief Editor of Borneo J Pharm
Borneo Journal of Pharmacy Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i1.2144

Abstract

Alhamdulillahirabbil ‘Alamin. The next edition of the Borneo Journal of Pharmacy (Borneo J Pharm), has been published in February 2021. Starting from this edition, Borneo J Pharm increases the frequency of publishing four times a year. This change aims to improve the circulation of the best articles published by Borneo J Pharm. Also, starting from this edition, Borneo J Pharm applying the publish-as-you-go issue to present the title of the article that has been received as early as possible in order to increase the chances of readability and quotation of articles in Borneo J Pharm. This edition includes writings from four countries including Indonesia, India, Malaysia, and Nigeria. The authors come from several institutions, including Universitas Muhammadiyah Palangkaraya, Universitas Muhammadiyah Surakarta, Universitas Muhammadiyah Malang, Universiti Teknologi MARA Cawangan Sarawak, Politeknik Bina Husada Kendari, Universitas Halu Oleo, Akademi Farmasi Surabaya, Universitas Hang Tuah, Universitas Mandala Waluya, Universitas Gadjah Mada, Universitas Abdurrab, Federal University of Technology Minna, Humera Khan College of Pharmacy, University of Abuja, and Universitas Ahmad Dahlan. Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions. The editorial board would like to thank all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors of the articles, could re-participate for publication in the next edition in May 2021.
Antidiabetic Activity of Extract Combination of Orthosiphon aristatus and Oryza sativa L. var glutinosa Eris Septiana; Nurul Maulida Rizka; Yadi Yadi; Partomuan Simanjuntak
Borneo Journal of Pharmacy Vol. 4 No. 3 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i3.2154

Abstract

Traditionally and scientifically, research has shown that Orthosiphon aristatus and Oryza sativa L. var. glutinosa have antidiabetic activity. The combination of two medicinal plants can increase their biological activity. This study aimed to determine the antidiabetic activity of O. aristatus and O. sativa L. var. glutinosa on single and combined extracts. Phytochemical screening of the single extract was done qualitatively. The α-glucosidase inhibitory method was used as an antidiabetic activity. The results showed that every extract contained alkaloids, steroids/triterpenoids, flavonoids, tannins, quinones, and coumarins. A single extract of O. sativa L. var glutinosa, O. aristatus, and their combinations (1:1, 1:2, and 2:1) had an α-glucosidase enzyme inhibitory activity with an IC50 value of 67.82, 80.93, 73.81, 88.72, and 61.51 µg/ml, respectively. The combination shows that the ratio of 1:1 was nearly additive, 1:2 was slight to moderate antagonism, and 2:1 was moderate to slight synergism. The combination of 96% ethanol extract of O. sativa L. var. glutinosa and O. aristatus in a ratio of 2:1 was the most effective in increasing its inhibitory activity.
Comparison of Patient's Satisfaction with Pharmaceutical Care Services in Ownership-Based Pharmacies in Semarang, Indonesia Nisa Febrinasari; Abdur Rosyid; Fadhila Huswatunnida
Borneo Journal of Pharmacy Vol. 5 No. 3 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i3.2158

Abstract

Implementation of pharmacists services provided in all pharmacies must meet the standard of pharmaceutical services guidelines, including the provision of drug information. The study aims to compare the patient's perception of drug counseling services by pharmacy staff based on the type of pharmacy ownership (franchise/non-franchise) in Semarang. This research is an observational study with a cross-sectional design. Samples were taken of 286 respondents with a quota sampling technique. Data were collected using an online google form questionnaire tested for validity and reliability. The statistical analysis results used the Mann-Whitney test with a p-value of <0.05. There is no significant difference between the patient's perception of the drug information counseling services by pharmacy staff at the franchise or non-franchise pharmacies in Semarang with a p-value of 0.264. This study also found that the standard information given by pharmacy staff is healthy eating and education about antibiotics used in the common cold. In addition, only 55% of respondents were sure that the pharmacy staff who gave them drug information in pharmacies was a pharmacist. Consequently, we humbly recommend that pharmacists consistently wear their pharmacist identification.
Use of Direct PCR Technique Without DNA Extraction in Confirmation Test for Salmonella typhimurium Bacteria on Meatball Samples Alfi Sophian; Ratna Purwaningsih; Muindar Muindar; Eka Putri Juniarti Igirisa; Muhammad Luthfi Amirullah
Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i4.2187

Abstract

The use of direct PCR technique without DNA extraction in the confirmation test for Salmonella typhimurium ATCC 14028 bacteria on meatball samples was carried out in the Food and Drug molecular biology testing laboratory Administration in Gorontalo. The basis of this research is to have an impact on economic value in carrying out the confirmation test for S. typhimurium ATCC 14028, where testing is carried out conventionally, namely DNA extraction, which requires a large amount of money. Hence, it is necessary to innovate to modify the testing phase so that it is more effective and efficient. The purpose of this study was to see whether the direct PCR technique without DNA extraction can be done for the confirmation test of S. typhimurium ATCC 14028 on meatball samples. This study's sample consisted of 20 types of meatball samples spiked with S. typhimurium ATCC 14028 cultures. The method used in this study was qPCR analysis using the SYBR Green method. Data analysis was carried out based on 2 main criteria: (1) Ct analysis and (2) Tm analysis. Real-time PCR analysis results obtained Ct values ​​in the range 14.14 - 15.20 with an average of 14.82 and Tm values ​​85.20 - 86.30 with an average of 85.79. Based on these data, it can be concluded that using direct PCR can be used for testing confirmation of S. typhimurium ATCC 14028 on meatball samples.
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 4 No. 2 May 2021 Chief Editor of Borneo J Pharm
Borneo Journal of Pharmacy Vol. 4 No. 2 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i2.2289

Abstract

Assalamu’alaikum Wr. Wb. Alhamdulillahirabbil ‘alamin. The next edition of the Borneo Journal of Pharmacy (Borneo J Pharm), has been published in May 2021. Starting from this volume, Borneo J Pharm increases the frequency of publishing four times a year. This change aims to improve the circulation of the best articles published by Borneo J Pharm. This edition contains ten articles consisting of Pharmacology-Toxicology, Pharmaceutical, Microbiology Pharmacy, and Clinical-Community Pharmacy. This edition includes writings from seven countries including Indonesia, India, Pakistan, Iran, Nepal, Uganda, and Nigeria. The authors come from several institutions, including Sekolah Tinggi Ilmu Kesehatan Borneo Lestari, Bandung Institute of Technology, Universitas Lambung Mangkurat, Universitas Muhammadiyah Banjarmasin, Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin, Shri Gopichand College of Pharmacy, Government College University Faisalabad, Islamic Azad University, Sardar Patel College of Pharmacy, Universal College of Medical Sciences, NKBR College of Pharmacy and Research Centre, Universitas Islam Bandung, Oxford College of Pharmacy, ATMS Group of Institutions, Institut Sains dan Teknologi Nasional, Mbarara University of Science and Technology, Kampala International University, Kebbi State University of Science and Technology Aliero, University Institute of Pharma Sciences Chandigarh University, and Laureate Institute of Pharmacy. The editorial board would like to thank all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors of the articles, could re-participate for publication in the next edition in August 2021. Wassalamu’alaikum Wr. Wb.

Page 12 of 30 | Total Record : 300

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