cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Mohammad Rizki Fadhil Pratama
Contact Email
mohammadrizkifadhilpratama@umpr.ac.id
Phone
+6287815093560
Journal Mail Official
bjop@umpr.ac.id
Editorial Address
Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya Building B 1st Floor, RTA Milono St. Km.1,5. Palangka Raya 73111, INDONESIA
Location
Kota palangkaraya,
Kalimantan tengah
INDONESIA
Borneo Journal of Pharmacy
Published by Universitas Muhammadiyah Palangkaraya
ISSN : -     EISSN : 26214814     DOI : https://doi.org/10.33084/bjop
Core Subject : Health,
Medicine & Pharmacology
Borneo Journal of Pharmacy publishes various scientific articles covering Pharmacy and Pharmaceutical Sciences in the field but not limited to: Pharmacology-Toxicology, including pharmacokinetics, pharmacodynamics, pharmacotherapy, and toxicology. Pharmacognosy-Phytochemistry, including pharmacognosy, phytochemistry, ethnobotany, and ethnopharmacology. Pharmaceuticals, including biopharmaceuticals, pharmaceutical technology, formulations, and biotechnology. Analytical Pharmacy-Medicinal Chemistry, including pharmaceutical chemistry, chemical analysis, medicinal chemistry, bioinformatics, pharmacy physics, pharmaceutical analysis, and method validation. Microbiology Pharmacy, including the antibacterial, antifungal, and antiviral activity test. Natural Product Development, including testing the pharmacological activity of extracts, fractions, and plant isolates. Clinical-Community Pharmacy, including monitoring usage, side effects, counseling, and drug use evaluation. Management Pharmacy, including drug management, drug use profiles, pharmaceutical administration, and marketing.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 301 Documents
 6   7   8   9   10 
Microscopical Investigation of Sideritis taurica Fatima Kazbekovna Serebryanaya; Irina Konovalova
Borneo Journal of Pharmacy Vol. 3 No. 3 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i3.1524

Abstract

This research presents the results of the morphological-anatomical study of grass organs above ground (leaves, stems, and flowers) from Sideritis taurica Steph. ex Willd. from the Lamiaceae family. The range of distribution of this species covers Eastern Europe, including Crimea, Caucasus. This plant is commonly found as an ornamental plant and grows in the southern and central regions of Russia. The purpose of this study is the anatomical and morphological study of the vegetative organs of S. taurica and the formation of diagnostic signs for reliable plant identification. The research material used was S. taurica herbicide samples collected in Crimea on the slopes of Mount Ay-Petri. Plant material is fixed in the glycerin : water system in a ratio of 1 : 1. Cross-section of stems and leaves is carried out using blades. The study was conducted with the morphological-anatomical method. The results obtained indicate the anatomical structure of the lamina, stem, and flower of the plant that has been studied. Anomocytic types of stomatal devices, unicellular and multicellular trichomes, located on the upper and lower sides of the leaf, as well as on the corolla stem and epidermis, have been discovered. The study carried out is part of the S. taurica complex pharmacognostic study.
Antibiotics Resistance Pattern of Coliform Bacteria Isolated from Slaughterhouse Wastewater in Jega Town, Kebbi State, Nigeria Adamu Almustapha Aliero; Namadina Hassan Jega; Ahmad Ibrahim Bagudo; Sahabi Sule Manga; Kabiru Hussaini
Borneo Journal of Pharmacy Vol. 3 No. 3 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i3.1530

Abstract

Wastewater is an essential reservoir of pathogenic bacteria, which include resistant strains. This study determined the antibiotics resistance pattern of Coliform bacteria isolated from slaughterhouse wastewater in Jega local government. Five different samples of wastewater from different locations of a slaughterhouse were collected using standard sample collection techniques. Coliform bacteria were isolated using the standard microbiological method. The total bacterial count was determined using plate count agar. Suspected coliforms were identified based on morphological and biochemical tests. Antimicrobial susceptibility testing was carried out using the standard disc diffusion method. The highest bacterial count (8.4x102 CFU/ml) was observed from the wastewater collection point, and the lowest bacterial (1.2x102 CFU/ml) count from the slaughtering point. Three Gram-negative bacteria, Escherichia coli, Pseudomonas aeruginosa, and Enterobacter aerogenes, were identified. Escherichia coli was the most frequently isolated in slaughterhouse wastewater 39 (45.8%). Among the antibiotics tested against isolated bacteria, Septrin was the most resistant antibiotics recorded against E. coli and E. aerogenes with 84.61% and 88.89% resistant, respectively. Pseudomonas aeruginosa was found to show higher resistance to Chloramphenicol and Septrin with 84.21% resistance each. The occurrence of antibiotic-resistant bacteria from slaughterhouse wastewater showed the risks associated with antimicrobial drug resistance transferred from food-producing animals to humans. Management concerns, such as local government health officers and community development officers, should increase the sensitization of slaughterhouse workers by organizing conferences or conducting radio talk to educates these slaughterhouse workers on the treatment of slaughterhouse wastewater and health risk associated with antimicrobial-drug resistance transferred from animals to humans.
Pharmacognostic Study and Antioxidant Activity of Mundar (Garcinia forbesii King.) leaves from Banua Botanical Gardens of South Kalimantan Sutomo Sutomo; Dina Noor Kamali; Arnida Arnida; Normaidah Normaidah; Agung Sriyono
Borneo Journal of Pharmacy Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i4.1541

Abstract

Mundar (Garcinia forbesii King.) is a plant from South Kalimantan. This plant has chemical contents that have potential as medicine. The purpose of this study is to provide a pharmacognostic picture of a specific, nonspecific and determine the antioxidant activity of G. forbesii leaves. Specific parameters include organoleptic, microscopic testing, thin-layer chromatography profiles, and phytochemical screening. Nonspecific parameters include total ash content, acid insoluble ash content, drying loss, water-soluble extract content, and ethanol-soluble extract content. Antioxidant activity was determined by the DPPH method based on IC50 values. Specific parameter test results are green powder, characteristic odor, and sour taste. Microscopic tests showed stomata, upper epidermis, lower epidermis, cell walls, xylem, phloem, palisade tissue, spongy tissue, and cuticles. Garcinia forbesii leaves contain alkaloids, flavonoids, phenols, tannins, and steroids. The TLC profile showed good separation of polar eluents, and yellow spots appeared after spraying DPPH reagents. The non-specific parameter test is the total ash content of 6.52±0.1%; acid insoluble ash content 1.06±0.08%; drying shrinkage 6.43±0.38%; water-soluble extracts 34.3±0.3%; and ethanol-soluble extracts 23.47±0.35%. Ethanol extract of G. forbesii leaves has antioxidant activity with IC50 of 65.7 ppm. Pharmacognostic study fulfills the requirements, and G. forbesii leaves extract has strong antioxidant activity.
Antibacterial Activity of Bandotan (Ageratum conyzoides L) Leaves Extracts Against Methicillin-Resistant Staphylococcus aureus Selvira Anandia Intan Maulidya; Doni Anshar Nuari; Shendi Suryana; Sumia Almarifah
Borneo Journal of Pharmacy Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i4.1552

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial infections throughout the world and can be life-threatening as well. This study aimed to determine the antibacterial activity of Bandotan (Ageratum conyzoides L) leaves ethanolic extract against MRSA's growth. Ageratum conyzoides leaves were extracted by ethanol and screened for their phytochemical constituent. Ethanolic extracts of A. conyzoides leaves were evaluated for their potential antibacterial activity using disc diffusion assay. The minimum inhibitory concentration (MIC) value was determined using the agar dilution method. Phytochemical screening shows that the extracts contain alkaloids, flavonoids, saponins, tannins, and steroids or triterpenoids. Ageratum conyzoides leaves extract shows a 25.1 mm inhibitory zone at 12.5% extract concentration with MIC value equivalents to 4.46 x 10-6 g of gentamicin. This study concludes that A. conyzoides leaves ethanolic extracts have potential antibacterial activity against MRSA.
Morphological and Micromorphological Investigations of Bidens frondosa L. from Flora of Krasnodar Region, Russia Vladimir Zinchenko; Fatima Kazbekovna Serebryanaya
Borneo Journal of Pharmacy Vol. 6 No. 1 (2023): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v6i1.1554

Abstract

Complex morphological and micromorphological studies have been made about bootjack bur (Bidens frondosa) growing on the territory of the Krasnodar region. The lamina is of dorsoventral type. The conduction system has fasciations, three closed collateral bundles, are present near the vein. The leaf is of amphistomatic type, stomatic apparats are present in a small amount. Anticlinical walls of the main cells of the epidermis are strongly flexuose. The lower epidermis if compared to the upper one has a large number of stomatic apparatus of anisocytic type. The trichomes are leggy, represented by multicellular hairs of different shapes and lengths. Micromorphological capabilities of bootjack bur’s transverse section of the caulis and leafstalk have been studied. Received micromorphological data is a fragment of complex pharmacognostic studies of the Bidens kind. For acquiring the anti-allergic medication in the future, it is necessary to make pharma-technological studies and come up with the necessary medical form in the shape of thick extract and also make pharmacological studies in acquiring this medical form.
Formulation and Evaluation of Solid Dispersion Chitosan Tablet from Whiteleg Shrimp (Litopenaeus vannamei) Using PVP K-30 As a Carriers Hilya Nur Imtihani; Fitria Abbas Thalib; Silfiana Nisa Permatasari
Borneo Journal of Pharmacy Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i1.1557

Abstract

Whiteleg shrimp (Litopenaeus vannamei) on the market are processed or sold only to take part in the meat. The head, shell, and tail are thrown away without any prior processing. Underutilized waste causes environmental problems. An alternative to overcome this environmental disturbance phenomenon is to utilize shrimp shells containing chitin and subsequently transformed into chitosan that can be applied in various fields. Chitosan has poor solubility in water but high permeability; thus, improve bioavailability is accomplished by making solid dispersions. This study aims to formulate and evaluate the solid dispersion tablet using chitosan extract from L. vannamei as an active agent with PVP K-30 as a carrier. The formulation divided into three groups, that was F1 (chitosan : PVP K-30 = 1 : 1 solid dispersion), F2 (chitosan : PVP K-30 = 1 : 3 solid dispersion), and F3 (pure chitosan). The result of chitosan solid dispersion was molded into tablets by the direct compression method. The tablets were evaluated by weight and size uniformity, hardness, friability, and disintegration time. All the formulas by weight and size uniformity as well as disintegration time fulfill the requirements. The hardness of the tablets from F3 with 4,275 kg was the best from F1 and F2. By statistic analytical from weight uniformity, hardness and disintegration time give significant difference with sig. <0.05.
Role of Cannabinoid Receptors in Psychological Disorder Ambika Nand Jha; Dhaval M Patel
Borneo Journal of Pharmacy Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i4.1569

Abstract

Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system. Cannabinoid CB1 and CB2 receptors are G protein-coupled receptors present from the early stages of gestation, which is involved in various physiological processes, including appetite, pain-sensation, mood, and memory. Due to the lipophilic nature of cannabinoids, it was initially thought that these compounds exert several biological effects by disrupting the cell membrane nonspecifically. Recent biochemical and behavioral findings have demonstrated that blockade of CB1 receptors engenders antidepressant-like neurochemical changes (increases in extracellular levels of monoamines in cortical but not subcortical brain regions) and behavioral effects consistent with antidepressant/antistress activity. We aim to define various roles of cannabinoid receptors in modulating signaling pathways and association with several pathophysiological conditions.
Validation of Finnish Diabetes Risk Score Indonesia Version in Yogyakarta Putri Pertiwi; Dyah Aryani Perwitasari; Satibi Satibi
Borneo Journal of Pharmacy Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i1.1575

Abstract

Diabetes mellitus (DM) has developed as a major public health problem in the world. It is estimated that around 50% of diabetics have not been diagnosed in Indonesia, and only two-thirds of those diagnosed are undergoing treatment. This condition must be prevented. The purpose of this study was to determine the validity and reliability of the Indonesian version of the Finnish Diabetes Risk Score (FINDRISC) as an instrument for predicting type 2 diabetes mellitus (T2DM). This study was an observational study with a cross-sectional design on 60 research subjects who were indigenous people of Yogyakarta who live in Yogyakarta, which can be proven by Identity Cards by the inclusion and exclusion criteria. Validity was tested by the validity of criteria by type while using the area under the receiver-operating curve (ROC-AUC). In contrast, reliability was tested by internal consistency using Cronbach's alpha. The results showed that as many as 14 people or 23.33% experienced uncontrolled fasting blood sugar and 15 people had a risk score of FINDRISC more than 10. Based on the ROC AUC analysis, the value of 0.935 (95% CI 0.865 1.00) with a cut-off point of 10 with the value of Sn = 85%, Sp = 95%, PPV = 85%, NPV = 95%, +LR = 5.66, and -LR = 0.15. Based on the reliability test, the Cronbach's alpha value of 0.727 was obtained. The FINDRISC questionnaire is categorized as valid and reliable so that it can be a screening tool for understanding.
The Combination of Turmeric (Curcuma domestica) Rhizome Extract and Collagen in A Serum Formulation as an Antioxidant Denia Pratiwi; Wahyu Margi Sidoretno; Nur Aisah
Borneo Journal of Pharmacy Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i1.1578

Abstract

Turmeric (Curcuma domestica) has nutritious compounds called curcuminoids, which can be used as antioxidants. As an antioxidant, C. domestica extract can be used to ward off free radicals that damage collagen and elastin, a protein that keeps skin moist. This study aimed to determine the antioxidant activity of serum combined with collagen's addition using the DPPH method. The DPPH was made at a concentration of 80 μg/mL, and the absorption was read at a wavelength of 520 nm using a microplate rider. The study was conducted by making six formulations: F0, F1, F2, F3, F4, and F5 obtained the results of serum made from C. domestica extract that could inhibit free radicals and meet the physical evaluation test requirements of serum. Furthermore, the formula was made using only one active ingredient and only collagen to determine the extract or collagen's antioxidant activity. The results obtained indicate that collagen had a supporting role in adding antioxidant activity apart from its extract. The highest % inhibition value at F5 with 90.526% could ward off free radicals.
Relationship Between Finnish Diabetic Risk Score (FINDRISC) with Health-Related Quality of Life in Yogyakarta Ninda Sari Wahyuningtyas; Dyah Aryani Perwitasari; Satibi Satibi
Borneo Journal of Pharmacy Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i1.1579

Abstract

The number of people with type 2 diabetes mellitus (T2DM) in Indonesia increases every year. Control of the development of T2DM can be done by screening using Finnish Diabetic Risk Score (FINDRISC)-Indonesian. FINDRISC is a valid tool for estimating the risk of T2DM within the next 10 years. This condition can have a major impact on the estimated life span and quality of life in the future. The purpose of this research is to determine the relationship between FINDRISC-Indonesian and respondent characteristics with HRQoL from EuroQol-5 Dimension-5 Level (EQ-5D-5L) in Yogyakarta. The cross-sectional study was conducted on 125 respondents who met the inclusion criteria. The risk of developing T2DM was assessed using a validated and widely used FINDRISC (range 0-26 points), and quality of life was measured by the EQ-5D-5L instrument. Overall data were analyzed using the Pearson correlation test and Independent t-test. The results showed the domain of pain was the domain that reported most respondents' most problems (28.8%). The respondent's utility value was 0.958 ± 0.69, and the VAS value was 79.4 ± 0.7. There was a significant difference in utility value based on age characteristics (p = 0.013). There was a relationship between age and utility value (p = 0.006) and FINDRISC score with utility value (p = 0.003). This study concludes that a high FINDRISC score affects the quality of life, and older age has a lower quality of life.

Page 8 of 31 | Total Record : 301

 6   7   8   9   10 

Filter by Year

2018 2025


Reset
Filter By Issues
All Issue Vol. 8 No. 4 (2025): Borneo Journal of Pharmacy Vol. 8 No. 3 (2025): Borneo Journal of Pharmacy Vol. 8 No. 2 (2025): Borneo Journal of Pharmacy Vol. 8 No. 1 (2025): Borneo Journal of Pharmacy Vol. 7 No. 4 (2024): Borneo Journal of Pharmacy Vol. 7 No. 3 (2024): Borneo Journal of Pharmacy Vol. 7 No. 2 (2024): Borneo Journal of Pharmacy Vol. 7 No. 1 (2024): Borneo Journal of Pharmacy Vol. 6 No. 4 (2023): Borneo Journal of Pharmacy Vol. 6 No. 3 (2023): Borneo Journal of Pharmacy Vol. 6 No. 2 (2023): Borneo Journal of Pharmacy Vol. 6 No. 1 (2023): Borneo Journal of Pharmacy Vol. 5 No. 4 (2022): Borneo Journal of Pharmacy Vol. 5 No. 3 (2022): Borneo Journal of Pharmacy Vol. 5 No. 2 (2022): Borneo Journal of Pharmacy Vol. 5 No. 1 (2022): Borneo Journal of Pharmacy Vol. 4 No. 4 (2021): Borneo Journal of Pharmacy Vol. 4 No. 3 (2021): Borneo Journal of Pharmacy Vol. 4 No. 2 (2021): Borneo Journal of Pharmacy Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19 Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy Vol. 3 No. 3 (2020): Borneo Journal of Pharmacy Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy Vol. 3 No. 1 (2020): Borneo Journal of Pharmacy Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy Vol. 2 No. 1 (2019): Borneo Journal of Pharmacy Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy More Issue