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Mohammad Rizki Fadhil Pratama
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Borneo Journal of Pharmacy
Published by Universitas Muhammadiyah Palangkaraya
ISSN : -     EISSN : 26214814     DOI : https://doi.org/10.33084/bjop
Core Subject : Health,
Medicine & Pharmacology
Borneo Journal of Pharmacy publishes various scientific articles covering Pharmacy and Pharmaceutical Sciences in the field but not limited to: Pharmacology-Toxicology, including pharmacokinetics, pharmacodynamics, pharmacotherapy, and toxicology. Pharmacognosy-Phytochemistry, including pharmacognosy, phytochemistry, ethnobotany, and ethnopharmacology. Pharmaceuticals, including biopharmaceuticals, pharmaceutical technology, formulations, and biotechnology. Analytical Pharmacy-Medicinal Chemistry, including pharmaceutical chemistry, chemical analysis, medicinal chemistry, bioinformatics, pharmacy physics, pharmaceutical analysis, and method validation. Microbiology Pharmacy, including the antibacterial, antifungal, and antiviral activity test. Natural Product Development, including testing the pharmacological activity of extracts, fractions, and plant isolates. Clinical-Community Pharmacy, including monitoring usage, side effects, counseling, and drug use evaluation. Management Pharmacy, including drug management, drug use profiles, pharmaceutical administration, and marketing.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 291 Documents
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Cover, Content, and Editorial Note from Borneo J Pharm Vol. 3 No. 2 May 2020 Chief Editor of Borneo J Pharm
Borneo Journal of Pharmacy Vol. 3 No. 2 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i2.1409

Abstract

Alhamdulillahirabbil ‘alamin. The next edition of Borneo Journal of Pharmacy (Borneo J Pharm), has been published in May 2020. Starting from this edition, Borneo J Pharm increases the frequency of publishing four times a year. This change aims to improve the circulation of the best articles published by Borneo J Pharm. Also, starting from this edition, Borneo J Pharm applying the publish-as-you-go issue to present the title of the article that has been received as early as possible in order to increase the chances of readability and quotation of articles in Borneo J Pharm. This edition contains six articles consisting of Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Microbiology Pharmacy, and Clinical-Community Pharmacy. This edition includes writings from four countries including Indonesia, India, Nigeria, and The Gambia. The authors come from several institutions, including Shri Gopichand College of Pharmacy, Universitas Halu Oleo, Universitas Airlangga, Sekolah Tinggi Ilmu Kesehatan Borneo Lestari, Universitas Muhammadiyah Bandung, Universitas Jenderal Achmad Yani, Akademi Farmasi Surabaya, Federal University Birnin-Kebbi, and London School of Hygiene and Tropical Medicine, Gambia. Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions. The editorial board would like to thank all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors of the articles, could re-participate for the publication in the next edition on August 2020.
Formulation and Evaluation of Natural Gel Containing Ethanolic Extract of Pandanus amaryllifolius R. Using Various Gelling Agents Dyera Forestryana; Annisa Hayati; Aristha Novyra Putri
Borneo Journal of Pharmacy Vol. 5 No. 4 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i4.1411

Abstract

Ethanol extract of Pandanus amaryllifolius leaves contains quercetin has anti-inflammatory properties. The gel dosage form is very appropriate for wound healing therapy because it gives a cold sensation to the skin. This study aims to formulate a P. amaryllifolius gel by variation of a gelling agent to compare the effect of a natural gelling agent, semi-synthetic gelling agent, and synthetic gelling agent on the physical characteristics of the gel. The gel formulation was made in three formulas. Evaluations include organoleptic, homogeneity, spreadability, adhesion, pH, and viscosity. The optimum gel formula was tested for release study using a dissolution apparatus 5. Determination of release kinetics model using the kinetics approach of zero-order, first-order, Higuchi, and Korsmeyer-Peppas. The organoleptic shows the gel's dark green color, P. amaryllifolius aromas, and good homogeneity. The gel formulas had pH values that matched the physical quality criteria of the gel. Data obtained for the spreadability test for F1, F2, and F3 were 12.16, 14.66, and 10.75 g.cm/sec, respectively. The F1, F2, and F3 adhesion test results were 11.66, 10, and 47.33, respectively. The viscosity of F1 was 15750 cps, F2 was 4807 cps, and F3 was 19380 cps. This study concludes that the optimum formula is obtained from the gelling agent of Na-CMC as a gelling agent. The number of quercetins released from F2 was 42.76%, and the release kinetics model followed the kinetics of Higuchi.
Review on COVID-19: Rise of SARS-CoV-2 Pandemic Outbreak Vidhan Chand Bala; Punet Kumar
Borneo Journal of Pharmacy Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3iSpecial-1.1412

Abstract

Initially recognized of COVID-19 within the world in 2019, the World Health Organization situational report from May 22nd, 2020, globally, there is a complete of 5,204,508 confirmed cases, with 212 countries being affected by the novel coronavirus. 2019 novel coronavirus (SARS-CoV-2) is that the seventh member of the family of coronaviruses is enveloped viruses with a positive sense, single-stranded RNA genome. The SARS-CoV-2 may be a β-CoV of group 2B there is 70% comparability in genetic sequence to SARS-CoV. The source of the new coronavirus infection has been resolved as bats. With whole-genome sequences of SARS-CoV-2 is 96% comparatively at the whole-genome level to a bat coronavirus. Mechanisms of transmission are concluded to incorporate contact, droplet, and possibly airborne under certain circumstances supported ancient experiences associated with SARS-CoV outbreaks. Although antiretroviral therapy is being widely used everywhere the globe for such patents, effects at finding a SARS-CoV vaccine haven’t succeeded so far.
Preliminary Survey on Knowledge, Attitudes, and Practices about the COVID-19 Pandemic among Residents in North Central Nigeria Elijah Edache Ehoche; Johnson Adejoh; Joseph Idoko; Chijioke Madu
Borneo Journal of Pharmacy Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3iSpecial-1.1413

Abstract

A preliminary survey on the knowledge, attitude, and practice of the COVID-19 pandemic among residence in North Central Nigeria, was conducted. An anonymous electronic network sampling survey designed by e-survey was employed. The result showed that on the level of knowledge and practice, 76.83% opined that people may be sick for 1-14 days without developing the symptoms. On the viral transmission, 94.41% agreed that the transmission of the virus can be through direct contact with contaminated surfaces through eyes, nose, and mouth, as well as 78.35%, responded that the virus doesn't penetrate the skin. More so 92.04% of the respondents showed that older and sick people are more vulnerable to the disease with 98.86% showing that the most common symptoms may include fever, tiredness, dry cough, and sometimes difficulty in breathing. Only 24.43% asserted that COVID-19 cannot be transmitted through social gatherings, going put often, making direct physical contact with people. Meanwhile, 21.02% showed COVID-19 is a punishment for immoral behavior. On the rate of the outbreak, 94.32% said it is scary. Only 55.11% asserted approval of the control approach by the government. However, 82.29% would agree with the response of the masses to government measures to control the spread. On the way forward, 98.87% advised the need for more research and 87.08% would approve of vaccination against the disease. This implies that the respondents have a good level of knowledge and practice about COVID-19 and necessary adjustments are needed to control or manage the spread of the pandemic.
Advantages of Herbal Over Allopathic Medicine in the Management of Kidney and Urinary Stones Disease Saurabh Nimesh; Vrish Dhwaj Ashwlayan; Rubi Rani; Om Prakash
Borneo Journal of Pharmacy Vol. 3 No. 3 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i3.1415

Abstract

Kidney and urinary stone disease (Nephrolithiasis and urolithiasis) are the condition where urinary stones or calculi are formed in the urinary tract. The problem of urinary stones is very ancient; these stones are found in all parts of the urinary tract, kidney, ureters, and the urinary bladder and may vary considerably in size. It is a common disease estimated to occur in approximately 12% of the population, with a recurrence rate of 70-81% in males and 47-60% in females. The treatment of kidney and urinary stone diseases such as a western (allopathy) medicine and surgery is now in trends. However, most people preferred plant-based (herbal) therapy because of the overuse of allopathic drugs, which results in a higher incidence rate of adverse or severe side effects. Therefore, people every year turn to herbal therapy because they believe plant-based medicine is free from undesirable side effects, although herbal medicines are generally considered to be safe and effective. In the present article, an attempt has been made to emphasize an herbal therapy is better than allopathic therapy for the management of the kidney and urinary stone disease.
Novel Coronavirus: A Newly Arranged Mini-Review Siwani Devi; Kishan Tripathi; Mohammad Mukim; Vidhi Jain; Nesar Ahmad; Noorul Hasan; Prashant Kumar Singh; Mohammad Khalid
Borneo Journal of Pharmacy Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3iSpecial-1.1428

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was originally known as a virus that infects animals and rarely can be transmitted to humans in large populations, is now transformed into one of the most feared pandemics causes worldwide. Infection by a virus that is officially known as COVID-19 has caused global concern mainly due to the number of deaths caused. Since it was first reported in Wuhan, China in December 2019, now COVID-19 has spread to almost all parts of the world with a very rapid spread rate. The main symptom of this infection is a respiratory disease accompanied by other symptoms that resemble flu-like illness. Everyone can suffer from COVID-19, but the elderly, toddlers, pregnant women, and people with certain diseases and disorders of the immune system show more severe symptoms. The disease is transmitted through inhalation or contact with droplets, where the incubation period ranges from 2 to 14 days. Until now, specific therapy to treat COVID-19 has not been found, with preventive measures taken to control its spread. In this mini-review, we will explain important information related to COVID-19.
Coronavirus-SARS-CoV-2: Biology and Problems in rRT-PCR Detection Maelita Ramdani Moeis; Anis Puji Rahayu; Nisa Ihsani; Wulan Pertiwi
Borneo Journal of Pharmacy Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3iSpecial-1.1429

Abstract

Coronavirus disease 2019 (COVID-19) first appeared in China in December 2019 and was declared a pandemic by the World Health Organization. COVID-19 is caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2), a new virus previously unknown to humans. Here we look at what is known about this virus, the main method for detecting the presence of this virus in a person who is used as a golden standard, and the problems that could arise in this detection method. Understanding the biology of the virus and the strengths and weaknesses of the detection method are important for patient management and for overcoming the pandemic.
Phytochemical and Cytotoxic Test of Durio kutejensis Root Bark on MCF-7 Cells Muhammad Priyadi; Haryoto Haryoto; Amaliyah Dina Anggraeni; Heng Yen Khong
Borneo Journal of Pharmacy Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i1.1443

Abstract

Durio kutejensis has known potential as herbal medicine in Kalimantan. Many things can be explored from D. kutejensis related pharmacological activity in every part of the plant included root bark. This study investigated the phytochemical content with a qualitative test and tested cytotoxic activities of D. kutejensis root bark on MCF-7 cell lines. Cytotoxic activity tested on MCF-7 cells with MTT assay method. The result showed that D. kutejensis root bark contains flavonoid, tannin, terpenoid, phenol, and saponin. IC50 value for ethanol extracts of root bark, n-hexane fractions, ethyl acetate fractions, and doxorubicin on MCF-7 cells were 761.29; 280.5; 207.08; and 0.25 μg/mL, respectively. In conclusion, D. kutejensis root bark has some secondary metabolites but no cytotoxic activity on MCF-7 cells. Further research is needed to explore the anticancer activity of secondary metabolites on some other cancer cells and other pharmacological activities.
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 3 Special Issue 1 June 2020 Chief Editor of Borneo J Pharm
Borneo Journal of Pharmacy Vol. 3 No. Special-1 (2020): Borneo Journal of Pharmacy: COVID-19
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3iSpecial-1.1480

Abstract

COVID-19 is currently the most researched topic worldwide. Apart from the effects that are caused by such a massive, also because the most effective therapies to treat it has still not been found. Therefore, researchers around the world seem to compete with time to research to find ways to overcome the global pandemic. Seeing this trend, the Borneo Journal of Pharmacy (Borneo J Pharm) does not want to be left behind to participate in sharing information related to COVID-19, and Alhamdulillahirabbil 'alamin, in the middle of 2020 Borneo J Pharm published its first Special Issue with the related Research and Review theme of COVID-19. This edition contains five articles both research articles and reviews from domestic and foreign authors. The authors came from four countries consisting of Indonesia, India, Saudi Arabia, and Nigeria. The authors also come from several institutions, including Kota College of Pharmacy, Dr. A.P.J. Abdul Kalam University, Raffles University, Oxford College of Pharmacy, Shri Gopichand College of Pharmacy, Federal University of Technology Minna, University of Abuja, Benue State Polytechnic, Rahul Sankrityayan College of Pharmacy, Jamia Hamdard, Chhatrapati Shahu Ji Maharaj University, Prince Sattam bin Abdulaziz University, and Universitas Muhammadiyah Bandung
Determination of Antiradical Activity, Total Phenolic, and Total Flavonoid Contents of Extracts and Fractions of Langsat (Lansium domesticum Coor.) Seeds Yamin Yamin; Ruslin Ruslin; Sabarudin Sabarudin; Nurramadhani A Sida; Henny Kasmawati; La Ode Muhammad Diman
Borneo Journal of Pharmacy Vol. 3 No. 4 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i4.1500

Abstract

Lansium domesticum Coor. is a fruit species from the Meliaceae family, which is a tropical plant native to Southeast Asia. Local citizens call it langsat, longkong, or duku and have used it as traditional medicine. The seeds of L. domesticum are used as a fever medicine, its bark is used to treat scorpion sting, and its leaves are used to repel mosquitoes. Because of its various uses, it is necessary to explore the antiradical potential of L. domesticum seeds. This study aims to determine the antiradical potential of L. domesticum seeds extract and fractions by using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and to discover compounds that act as antiradical. Lansium domesticum seed powder was macerated with methanol, and then the extract was concentrated using a rotary evaporator and fractionated by n-hexane and ethyl acetate. The antiradical assay was conducted on extract and fractions by using DPPH radicals. Phenolic and flavonoid contents from extract and fractions were also tested. The ethyl acetate fraction obtained strong antiradical potential with an IC50 value of 8.938 ± 0.031 µg/mL. Total phenolic and flavonoid contents of ethyl acetate fraction were higher with values ​​of 58.25 ± 0.501 mgGAE/g sample and 75.123 ± 0.175 mgQE/g sample, respectively. Correlation of phenolic and flavonoid contents, which inhibited radicals had R2 values ​​of 0.9182 and 0.7658. Ethyl acetate fraction of L. domesticum seeds had very strong antiradical activity. Further isolation is expected to be conducted to discover which compounds are the most responsible as antiradical.

Page 7 of 30 | Total Record : 291

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