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The International Journal of Medical Science and Health Research

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Published by International Medical Journal Corp. Ltd.

ISSN : 30481376 EISSN : 30481368 DOI : -

Core Subject : Health,

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

The International Journal of Medical Science and Health Research, published by International Medical Journal Corp. Ltd. is dedicated to providing physicians with the best research and important information in the world of medical research and science and to present the information in a format that is understandable and clinically useful. Committed to publishing multidisciplinary research that spans the entire spectrum of healthcare and medicine access, The American Journal of Medical Science and Health Research aims at an international audience of pharmacists, clinicians, medical ethicists, regulators, and researchers, providing an online forum for the rapid dissemination of recent research and perspectives in this area.

Arjuna Subject : Kedokteran - Review dan Referensi, Kedokteran

Articles 529 Documents

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A Comprehensive Literature Review of Consumption of 100% Fruit Juice and Body Weight in Children and Adults Steven, Steven; Adrian, Adrian; Widia, Widia
The International Journal of Medical Science and Health Research Vol. 5 No. 3 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/vnjnd957

Background: The literature on the consumption of 100% fruit juice and its implications for body weight in children and adults reveals a nuanced and often contentious landscape. The introduction establishes the importance of distinguishing between 100% fruit juice and sugar-sweetened beverages, a point underscored by (Benton & A Young, 2019), who argue that conflating these two categories may lead to misleading conclusions regarding health outcomes. Their analysis indicates that while some studies suggest a long-term weight increase associated with fruit juice consumption, this may not apply to 100% fruit juice, which holds a different nutritional profile. Literature Review: Collectively, the literature indicates that while there are concerns about the caloric density and lower fiber content of 100% fruit juice, its role in enhancing diet quality and meeting nutritional needs cannot be overlooked. The evidence suggests that moderate consumption of 100% fruit juice may not be directly linked to increased body weight, particularly when compared to sugar-sweetened beverages. The ongoing debates underscore the need for continued research to disentangle the effects of 100% fruit juice from those of added sugars and to better understand its place within broader dietary patterns. Conclusion: In conclusion, the current body of literature presents a complex interplay between 100% fruit juice consumption, nutrient intake, and body weight. While some studies indicate potential risks associated with juice consumption, others highlight its contributions to diet quality and nutritional adequacy, especially in vulnerable populations. The findings collectively advocate for a more nuanced understanding of the role of 100% fruit juice in dietary habits and its implications for health outcomes.

A Comprehensive Literature Review of Implications of Preoperative Depression for Lumbar Spine Surgery Outcomes Arief, Arief; Rizki Kurnia, Rizki Kurnia; Catherine, Catherine
The International Journal of Medical Science and Health Research Vol. 5 No. 3 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/vtxg5s54

Background: The literature reviewed emphasizes the significant impact of preoperative depression on surgical outcomes for patients undergoing lumbar spine surgery. The studies collectively highlight a consistent link between depressive symptoms and adverse postoperative results, suggesting that psychological health is a critical factor influencing recovery trajectories. Literature Review: The foundational study by (Sinikallio et al., 2010) provides compelling evidence that both preoperative and postoperative depressive symptoms predict poor surgical outcomes. This research underscores the importance of mental health not only before surgery but also during the rehabilitation process, indicating that ongoing depressive symptoms can exacerbate recovery challenges. Further expanding on this theme, (L. Jackson et al., 2019) conducted a systematic review that connects psychological comorbidities with postoperative complications. Their work reveals that preoperative depression correlates with increased rates of delirium, readmissions, and prolonged hospital stays, suggesting that elevated cortisol levels in depressed individuals may be a contributing factor to these adverse outcomes. Additionally, the retrospective study by (Zhang et al., 2023) specifically examines the effects of preoperative depression on outcomes following cervical laminoplasty, providing valuable insights that can be extrapolated to lumbar spine surgeries. Conclusion: In conclusion, the literature consistently demonstrates that preoperative depression is a significant predictor of surgical outcomes in lumbar spine surgery. The integration of psychological assessments into preoperative evaluations is essential for optimizing patient care and enhancing recovery trajectories. Addressing mental health prior to surgery could mitigate adverse outcomes and improve overall patient well-being, highlighting the need for targeted interventions in this population.

A Comprehensive Literature Review of Long-Term Use of Muscle Relaxant Medications for Chronic Pain Stefanus, Stefanus; Aditya, Aditya; Andhika, Andhika
The International Journal of Medical Science and Health Research Vol. 5 No. 3 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/cz5taz49

Background: The literature on the long-term use of muscle relaxant medications for chronic pain reveals a nuanced landscape characterized by varying degrees of efficacy, safety concerns, and the potential for combination therapies. The introduction establishes the complexity of chronic pain management, emphasizing the need for a multifaceted approach that includes both pharmacological and non-pharmacological interventions. Literature Review: The systematic reviews by (Orrillo et al., 2022) and (M. Weisman et al., 2024) provide a critical lens on the efficacy and tolerability of muscle relaxants, revealing a lack of substantial evidence supporting their long-term use in chronic pain management. The findings emphasize the need for cautious application of these medications, particularly given the potential for adverse effects and the ambiguities surrounding their effectiveness over extended periods. Lastly, the exploration of muscle relaxants' role in post-chemotherapy and radiotherapy contexts, as discussed by (Radkowski et al., 2024), broadens the scope of their application, indicating that muscle relaxants may serve a critical function beyond traditional pain management. This perspective encourages further inquiry into their long-term efficacy and safety in various clinical settings. Conclusion: In conclusion, the literature presents a complex picture of muscle relaxants in chronic pain management. While they may provide short-term relief, their long-term use raises significant safety and efficacy concerns. The integration of combination therapies and non-pharmacological interventions appears crucial for optimizing treatment strategies. Future research is necessary to clarify the long-term implications of muscle relaxant use and to establish more definitive guidelines for their application in chronic pain management.

Application of Topical Phosphodiesterase 4 Inhibitors in Mild to Moderate Atopic Dermatitis Maria Elsa, Maria Elsa; Marsela, Marsela
The International Journal of Medical Science and Health Research Vol. 5 No. 4 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/dpr7vr91

Background: The application of topical phosphodiesterase 4 (PDE4) inhibitors in the treatment of mild to moderate atopic dermatitis (AD) has emerged as a significant area of interest in dermatological research. The literature presents a comprehensive overview of the efficacy, safety, and therapeutic potential of these agents, particularly focusing on crisaborole and difamilast, which have shown promise in clinical settings. Literature Review: The foundational work by (Li et al., 2018) highlighted the efficacy and safety of crisaborole, establishing it as a viable non-steroidal treatment option for AD. This pivotal study demonstrated the ability of crisaborole to reduce inflammation by inhibiting pro-inflammatory cytokines, a mechanism that is crucial given the chronic nature of AD and the need for effective long-term management strategies. The safety profile of crisaborole, particularly its tolerability in pediatric populations, supports its role as a preferred alternative to traditional corticosteroids, which often come with significant side effects. Further expanding the therapeutic landscape, (Sharma et al., 2018) introduced East Indian sandalwood oil as a PDE4 inhibitor, suggesting its potential as a natural treatment option for inflammatory skin diseases, including AD. This exploration of alternative therapies enriches the available treatment modalities, particularly for patients seeking non-pharmacological interventions. Conclusion: In conclusion, the literature collectively supports the therapeutic potential of topical PDE4 inhibitors in managing mild to moderate atopic dermatitis. The studies reviewed emphasize their efficacy in reducing inflammation and pruritus while maintaining a favorable safety profile, thus presenting a promising alternative to conventional treatments. However, ongoing research is essential to fully understand the long-term effects and optimize treatment strategies for diverse patient populations.

Aberrations in Peripheral Inflammatory Cytokine Levels in Parkinson Disease Jessica, Jessica; Johan, Johan
The International Journal of Medical Science and Health Research Vol. 5 No. 4 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/dwz5a061

Background: The literature on peripheral inflammatory cytokine levels in Parkinson's disease (PD) reveals a multifaceted relationship between immune responses and disease pathology. Early foundational work emphasized the crucial roles of both central and peripheral inflammation in PD progression, positing that immune dysregulation may precede neurodegeneration (Su & J. Federoff, 2014). This perspective is supported by subsequent studies that delve into the role of α-synuclein in sustaining neuroinflammation, highlighting the dual nature of inflammatory processes that can initially appear beneficial yet ultimately lead to neuronal degeneration (Pessoa Rocha et al., 2015). Literature Review: Recent research has further established a correlation between elevated levels of peripheral inflammatory cytokines and the severity of motor symptoms in PD, suggesting that inflammation is not merely a byproduct of the disease but a significant contributor to its clinical manifestations (Diaz et al., 2022). Historical analyses have documented the presence of activated microglia and elevated cytokines in PD patients, linking these findings to the progression of motor symptoms (Heidari et al., 2022). The systemic nature of inflammation in PD has been underscored by studies that connect peripheral immune responses to central neuroinflammatory processes, indicating that PD affects various bodily systems (P. Williams et al., 2022). Moreover, the exploration of biomarkers of inflammation in both blood and cerebrospinal fluid (CSF) has illuminated the role of microglial activation and cytokine release in PD progression (Zimmermann & Brockmann, 2022).. Conclusion: In conclusion, the body of literature underscores the significance of peripheral inflammatory cytokines in the pathophysiology of PD. The interplay between central and peripheral immune responses is critical in understanding the disease's progression and symptomatology. Future research should continue to explore these interactions, as they hold potential for developing targeted therapeutic strategies aimed at mitigating inflammation and its effects on PD.

Accuracy of machine learning models using ultrasound images in prostate cancer diagnosis Christine, Christine; Fransiska, Fransiska
The International Journal of Medical Science and Health Research Vol. 5 No. 4 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/mq778123

Background: The literature on the accuracy of machine learning models using ultrasound images in prostate cancer diagnosis reveals a dynamic landscape marked by both significant advancements and persistent challenges. The introduction establishes the importance of integrating machine learning with ultrasound imaging to improve diagnostic precision, particularly in a domain fraught with high stakes due to the complexities associated with prostate cancer. The initial studies highlight the potential of machine learning to standardize interpretations, as evidenced by the comparative analysis of labeling strategies that demonstrated superior performance with digital pathologist annotations over radiologist labels (Bhattacharya et al., 2021). Literature Review: As the review progresses, it becomes clear that traditional ultrasound imaging faces limitations, such as low resolution and high inter-observer variability, which can compromise diagnostic accuracy (Akatsuka et al., 2022). The literature advocates for the application of artificial intelligence (AI) technologies to enhance the reliability of cancer grading, emphasizing the critical role of accurate pathological grading in treatment decision-making. Further analysis reveals a growing body of work focused on the integration of advanced machine learning techniques, including deep learning and hybrid models that combine traditional and innovative approaches (Luijten et al., 2022). Conclusion: In conclusion, the literature collectively underscores the transformative potential of machine learning and deep learning techniques in enhancing the accuracy of prostate cancer diagnosis using ultrasound images. Despite the promising advancements, the field faces critical challenges, particularly regarding the need for robust datasets, the integration of AI into clinical practice, and the necessity for standardized evaluation criteria. Addressing these challenges will be pivotal in realizing the full potential of AI technologies in improving diagnostic outcomes and patient management in prostate cancer.

Aerobic Physical Activity and Depression Among Patients With Cancer Giovanni, Giovanni; Michelle, Michelle
The International Journal of Medical Science and Health Research Vol. 5 No. 4 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/70jndj94

Background: The literature presents a compelling case for the role of aerobic physical activity in alleviating depressive symptoms among cancer patients, particularly breast cancer survivors. The foundational analysis by (D Patsou et al., 2017) underscores the prevalence of depression in breast cancer survivorship, with rates ranging from 1.5% to 46%, and emphasizes the potential of physical activity as a non-pharmacological intervention. Their meta-analysis reveals that regular exercise can mitigate treatment-related side effects and improve survival outcomes, although they caution against the non-uniform reporting of exercise interventions, which complicates the interpretation of optimal exercise regimens ((D Patsou et al., 2017)). Literature Review: Building on this foundation, the critical analysis by (Marconcin et al., 2022) reinforces the efficacy of supervised aerobic exercise, noting that structured programs yield better psychological outcomes compared to unsupervised activities. Their findings highlight the importance of the exercise environment, suggesting that social interactions and professional guidance enhance adherence and motivation, which are crucial for effective mental health interventions in this population ((Marconcin et al., 2022)). Conclusion: In conclusion, the synthesis of these studies indicates that aerobic physical activity is a critical component in managing depression among cancer patients, particularly breast cancer survivors. While challenges remain regarding the standardization of exercise protocols and the need for tailored interventions, the integration of structured physical activity into treatment plans holds significant promise for enhancing the psychological well-being of cancer survivors. Future research should focus on addressing methodological limitations and exploring individualized exercise regimens to optimize mental health outcomes in this vulnerable population.

A Comprehensive Literature Review of Olfactory Impairment and Frailty Angelica, Angelica; Laurensia, Laurensia; Kemala Putri, Kemala Putri
The International Journal of Medical Science and Health Research Vol. 5 No. 5 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/9kj04b74

Background: The literature on olfactory impairment and its connection to frailty reveals significant insights into how sensory decline impacts various aspects of health and well-being in older adults. The foundational work by (Wongrakpanich et al., 2016) establishes the prevalence of olfactory dysfunction and its predictive value for cognitive decline and mortality. This is further supported by (S. Fluitman et al., 2019), who elucidate the relationship between olfactory impairment and nutritional health, highlighting how diminished olfactory function can lead to appetite suppression and subsequent undernutrition, thereby contributing to frailty. Literature Review: The exploration of age-related olfactory decline by (Kondo et al., 2020) emphasizes the multifactorial nature of this sensory loss, identifying lifestyle factors such as smoking and sinonasal diseases that exacerbate olfactory dysfunction. Moreover, (Tzeng et al., 2021) draw parallels between olfactory impairment and neurodegenerative diseases, suggesting that olfactory dysfunction may serve as a critical early indicator of cognitive decline, particularly in Alzheimer's disease.The research by (Iritani et al., 2021) and (Park et al., 2021) extends this discourse by linking olfactory deficits to geriatric syndromes, reinforcing the notion that sensory health is intertwined with cognitive function and overall frailty. Conclusion: In conclusion, the body of literature presents a compelling case for the significance of olfactory health in the context of frailty among older adults. The multifaceted relationships between olfactory impairment, cognitive decline, nutritional health, physical strength, and social interactions highlight the need for comprehensive approaches to assess and address sensory health in geriatric care. Interventions aimed at improving olfactory function could play a pivotal role in enhancing the quality of life and mitigating the adverse effects of frailty in this vulnerable population.

A Comprehensive Literature Review of Palliative Care Interventions for Surgical Patients Yosua Kurnia, Yosua Kurnia; Margaretha, Margaretha
The International Journal of Medical Science and Health Research Vol. 5 No. 5 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/0g6ap573

Background: The literature on palliative care interventions for surgical patients demonstrates a growing recognition of the complexities and unique needs of this population. The interdisciplinary nature of palliative care, as highlighted by (Li et al., 2016), underscores the necessity of improving quality of life (QOL) for patients with serious illnesses, while also addressing the methodological challenges in evaluating treatment efficacy. This foundational work emphasizes the importance of innovative analytic approaches to understand longitudinal QOL trajectories, which can ultimately guide clinical practice in palliative settings. Literature Review: The exploration of innovative care models, such as the Perioperative Surgical Home and Enhanced Recovery After Surgery, by (G. Harrison et al., 2021) suggests that these frameworks can enhance care coordination and improve patient outcomes during the perioperative period. Similarly, (C. Ferre et al., 2022) emphasize the importance of implementing palliative care programs in trauma and emergency settings to address the immediate needs of surgical patients. The holistic understanding of total pain in oncologic palliative care, presented by (Aparecida Gomes-Ferraz et al., 2022), stresses the necessity of addressing not only physical pain but also emotional distress through a multidisciplinary team approach. This aligns with the findings of (Lee et al., 2024), who call for a more coordinated approach to interventional procedures for managing cancer pain, highlighting the barriers to optimal pain management in this diverse population. Conclusion: In conclusion, the reviewed literature collectively underscores the importance of innovative, multidisciplinary approaches to palliative care interventions for surgical patients. There is a clear need for comprehensive strategies that address the unique challenges faced by this population, focusing on improving pain management, enhancing quality of life, and fostering effective interdisciplinary collaboration. The evolving landscape of palliative care necessitates ongoing research and practice improvements to ensure that surgical patients receive holistic and effective care throughout their treatment journey.

A Comprehensive Literature Review of Physician Posttraumatic Stress Disorder During COVID-19 Stefanus, Stefanus; Vanessa, Vanessa
The International Journal of Medical Science and Health Research Vol. 5 No. 5 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/bkw41008

Background: The literature review highlights the significant psychological impact of the COVID-19 pandemic on healthcare professionals, particularly concerning the prevalence of post-traumatic stress disorder (PTSD). The initial studies, such as the one by (A. Marco et al., 2020), revealed that emergency physicians reported PTSD symptoms, with identified stressors including disinformation and workload. This early finding set the groundwork for subsequent research, which consistently indicated that high-stress environments and inadequate resources contribute to the risk of PTSD among healthcare workers ((d’Ettorre et al., 2020); (Batra et al., 2020)). Literature Review: As the pandemic unfolded, studies demonstrated that healthcare professionals faced compounded psychological burdens, with factors such as long working hours and emotional exhaustion exacerbating their vulnerability to PTSD ((Luiz Carvalho Braule Pinto et al., 2021); (Chang et al., 2022)). The findings from (Sun et al., 2021) emphasized the alarming prevalence of PTSD symptoms and the lack of targeted interventions for healthcare providers, indicating a critical gap in the existing literature. Furthermore, the emotional toll of the pandemic was linked to increased anxiety and psychological distress, underscoring the need for ongoing research and support systems to address these issues ((De Pasquale et al., 2022)). Conclusion: Collectively, the studies reviewed indicate a concerning trend regarding the mental health of healthcare professionals during the COVID-19 pandemic, with PTSD emerging as a significant issue that requires urgent attention. The evidence points to the necessity for systematic assessments, targeted interventions, and robust support systems to address the mental health challenges faced by this critical workforce, particularly as the long-term consequences of untreated PTSD could adversely affect both healthcare providers and patient care.

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Contact Name Indra Hadi

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Journal Mail Official pt.internationalmedicaljournal@gmail.com

Editorial Address Equity Tower. 49th Floor. Sudirman Street. Special Region of Jakarta, Indonesia

Location Kota adm. jakarta selatan, Dki jakarta INDONESIA

Abstract

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Contact Name
Indra Hadi

Contact Email
profesionaljournalmedicine@gmail.com

Phone
-

Journal Mail Official
pt.internationalmedicaljournal@gmail.com

Editorial Address
Equity Tower. 49th Floor. Sudirman Street. Special Region of Jakarta, Indonesia

Location
Kota adm. jakarta selatan,

Dki jakarta

INDONESIA