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The International Journal of Medical Science and Health Research

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Published by International Medical Journal Corp. Ltd.

ISSN : 30481376 EISSN : 30481368 DOI : -

Core Subject : Health,

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

The International Journal of Medical Science and Health Research, published by International Medical Journal Corp. Ltd. is dedicated to providing physicians with the best research and important information in the world of medical research and science and to present the information in a format that is understandable and clinically useful. Committed to publishing multidisciplinary research that spans the entire spectrum of healthcare and medicine access, The American Journal of Medical Science and Health Research aims at an international audience of pharmacists, clinicians, medical ethicists, regulators, and researchers, providing an online forum for the rapid dissemination of recent research and perspectives in this area.

Arjuna Subject : Kedokteran - Review dan Referensi, Kedokteran

Articles 529 Documents

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A Comprehensive Literature Review of Red Flag Signs and Symptoms for Patients With Early-Onset Colorectal Cancer Anthony, Anthony; Christian, Christian
The International Journal of Medical Science and Health Research Vol. 5 No. 5 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/c5qgx796

Background: The literature on early-onset colorectal cancer (EOCRC) reveals a complex interplay of symptoms, diagnostic challenges, and the need for increased awareness among both patients and healthcare providers. The systematic review by (Mitchell et al., 2007) underscores the necessity of recognizing red flag symptoms such as rectal bleeding and changes in bowel habits, as these are critical for timely diagnosis and intervention. The study highlights that delays in diagnosis can lead to more advanced disease stages, emphasizing the importance of patient education regarding the seriousness of these symptoms. Literature Review: Further investigations, such as those by (Renzi et al., 2016), reveal that many patients present with significant symptoms well before their diagnosis, indicating a gap in timely medical consultation. The findings suggest that abdominal pain and rectal bleeding are prevalent among emergency presentations, yet many patients do not receive timely evaluations, leading to missed opportunities for early intervention.The exploration of risk factors by (R Syed et al., 2019) highlights the challenges faced by younger patients, who often misinterpret their symptoms, resulting in substantial delays in seeking medical attention. This trend is echoed in the study from Indonesia by (Makmun et al., 2021), which notes that abdominal pain is the most common presenting symptom among early-onset CRC patients. The demographic characteristics presented in this study further emphasize the need for targeted screening and awareness initiatives.. Conclusion: In conclusion, the literature collectively emphasizes the critical need for heightened awareness and education regarding the red flag signs and symptoms of early-onset colorectal cancer. There is a clear call for improved diagnostic protocols and screening strategies to enhance early detection and treatment outcomes for this vulnerable population. Addressing both patient and healthcare provider awareness is essential to mitigate delays in diagnosis and improve prognosis for young patients with EOCRC

A Comprehensive Literature Review of Aldosterone Antagonist Therapy and Mortality in Patients With ST-Segment Elevation Myocardial Infarction Without Heart Failure Zulkarnain, Zulkarnain; Yogi, Yogi; Elizabeth, Elizabeth
The International Journal of Medical Science and Health Research Vol. 5 No. 6 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/1tfjtp12

Background: The literature review presents a comprehensive analysis of aldosterone antagonist therapy in the context of ST-segment elevation myocardial infarction (STEMI) among patients without heart failure. The introduction highlights the significance of the renin-angiotensin-aldosterone system (RAAS) and its impact on cardiovascular health, particularly in acute myocardial infarction scenarios. Literature Review: The main body of the review discusses several key studies that examine the effectiveness and safety of aldosterone antagonists in STEMI patients. The findings from (M Nappi & Sieg, 2011) emphasize the adverse effects of RAAS, while studies such as (Y. Wang et al., 2016) and (Pitts et al., 2017) suggest that the mortality benefits of aldosterone antagonists may not extend to patients without heart failure. The meta-analysis by (Beygui et al., 2018) further supports the notion that mineralocorticoid receptor antagonists (MRAs) can reduce mortality in STEMI patients, indicating their potential utility even in the absence of overt heart failure. Conclusion: In conclusion, the literature presents a nuanced perspective on the role of aldosterone antagonists in managing STEMI patients without heart failure. While there is substantial evidence supporting their efficacy in heart failure contexts, the implications for patients without heart failure remain less clear. The existing studies indicate that while these agents may offer some benefits, their overall impact on mortality in this specific demographic is limited. Further research, particularly well-designed randomized trials, is essential to elucidate the therapeutic potential of aldosterone antagonism in improving outcomes for patients who experience myocardial infarction without concurrent heart failure.

A Comprehensive Literature Review of Anticholinergic Drug Exposure and the Risk of Dementia Pratiwi, Pratiwi; Elsa, Elsa; Aditya, Aditya
The International Journal of Medical Science and Health Research Vol. 5 No. 6 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/5wvkta37

Background: The literature surrounding anticholinergic drug exposure and its association with dementia has expanded significantly, revealing critical insights into the risks these medications pose, particularly for older adults. The foundational work by (Campbell et al., 2009) established the prevalence of anticholinergic medication use in this vulnerable demographic and highlighted serious cognitive side effects, including attention deficits and hallucinations. This concern is underscored by physiological changes in older adults that increase their susceptibility to such drugs, suggesting that clinicians must carefully weigh the risks versus benefits when prescribing anticholinergic medications. Literature Review: The cumulative effects of anticholinergic drug exposure were examined in detail by (A. C. Coupland et al., 2019), who found a significant correlation between higher cumulative use and increased dementia risk. This study emphasizes the importance of evaluating long-term medication regimens in older patients, particularly those on multiple prescriptions that may include anticholinergic agents. The findings support the notion that while short-term use can lead to immediate cognitive deficits, the long-term implications are critical and warrant further investigation. Conclusion: In conclusion, the body of literature increasingly points towards a significant association between anticholinergic drug exposure and the risk of dementia, particularly in older adults. While certain medications may carry lesser risks, the cumulative exposure to anticholinergic agents appears to be a critical factor in cognitive decline. Ongoing research is essential to clarify these relationships and guide clinical decision-making, ensuring that the prescribing of anticholinergic medications is conducted with a thorough understanding of their potential long-term cognitive implications.

Antiepileptic Drug Exposure in Infants of Breastfeeding Mothers With Epilepsy Frankie, Frankie; Muhammad Arief, Muhammad Arief; Florence, Florence
The International Journal of Medical Science and Health Research Vol. 5 No. 6 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/q4311x78

Background: The literature on antiepileptic drug (AED) exposure in breastfeeding mothers with epilepsy reveals a complex interplay between the management of maternal health and the potential risks to infants. Research indicates that epilepsy occurs in approximately 0.3-0.7% of pregnancies, with AEDs being linked to congenital disorders and developmental impairments in newborns (Reza Najafi et al., 2012). The careful balancing of seizure control and fetal safety is paramount, as uncontrolled seizures can pose significant risks to both the mother and the fetus (Ikeda-Sakai et al., 2019). Literature Review: The implications of AED exposure extend to breastfeeding, where concerns about drug presence in breast milk must be weighed against the potential cognitive benefits of breastfeeding for infants (Khuda & Aljaafari, 2018). While some studies suggest that breastfeeding may confer advantages that outweigh the risks associated with AED exposure, healthcare providers must guide mothers on optimal feeding practices to minimize infant exposure (Khuda & Aljaafari, 2018). Folic acid supplementation emerges as a critical preventive strategy, particularly for women on AEDs, to mitigate the risk of neural tube defects and other developmental issues (Ikeda-Sakai et al., 2019). This underscores the necessity for ongoing education and counseling for women with epilepsy regarding their medication management and nutritional needs during pregnancy and breastfeeding (Kashif et al., 2019). Conclusion: In conclusion, the literature emphasizes the need for individualized care for women with epilepsy who are pregnant or breastfeeding. The potential risks associated with AED exposure must be carefully managed through expert consultation, ongoing monitoring, and the implementation of preventive strategies such as folic acid supplementation. Continued research is vital to better understand the long-term effects of AEDs on infant development and to inform clinical practice.

Antiviral treatment of COVID-19 Andina, Andina; Sugiarto, Sugiarto; Pamungkas, Pamungkas
The International Journal of Medical Science and Health Research Vol. 5 No. 6 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/3kv7z420

Background: The literature on antiviral treatments for COVID-19 reflects a rapidly evolving field, characterized by a diversity of therapeutic strategies and ongoing clinical investigations. The collaborative efforts of various institutions have been pivotal in identifying effective treatment options, as evidenced by the RECOVERY trial's findings on dexamethasone and remdesivir's efficacy (Sarkar et al., 2020). The urgency for effective treatments is underscored by the ongoing transmission of the virus and the emergence of new variants, necessitating a comprehensive evaluation of available antiviral agents. Literature Review: Favipiravir has emerged as a significant candidate for treating mild to moderate COVID-19 cases, with systematic reviews and meta-analyses indicating its clinical efficacy (Hassanipour et al., 2021). The comparative analysis of favipiravir and remdesivir highlights their mechanisms of action, reinforcing the need for continued exploration of these and other antiviral options (Andrei Negru et al., 2022). Furthermore, molnupiravir has gained attention for its promising pharmacokinetics and clinical trial results, demonstrating its potential in the antiviral arsenal against COVID-19 (Khiali et al., 2022). The landscape of antiviral therapies is further enriched by a comprehensive review of small-molecular therapeutics, emphasizing the need for novel strategies to address the challenges posed by emerging variants (Zhong et al., 2022). The repurposing of established drugs with known safety profiles remains a critical area of focus, as highlighted by the analysis of various antiviral agents, including remdesivir and favipiravir (Sahin et al., 2022).. Conclusion: In conclusion, the body of literature reflects significant advancements in the antiviral treatment of COVID-19 while highlighting the complexities and challenges that remain. The continuous evaluation and adaptation of therapeutic strategies are essential to effectively combat the evolving landscape of COVID-19 and its associated variants.

THE EFFECT OF SOCIAL MEDIA MARKETING ACTIVITIES ON BRAND LOYALTY WITH BRAND IMAGE AND BRAND AWARENESS AS MEDIATION VARIABLES AT XYZ BEAUTY CLINIC IN JAKARTA Sukidy, Beatrice; Achmadi, Hendra
The International Journal of Medical Science and Health Research Vol. 5 No. 7 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/6b81sq65

Background: Social media has become an effective platform for marketing products and increasing brand existence amidst intense business competition. Methods: This research aims to examine the influence of social media marketing activities on brand awareness, brand image and brand loyalty in the beauty clinic industry. These concepts were measured as mediating variables, and research was conducted on 160 respondents who were customers of beauty clinics using quantitative methods and SEM-PLS analysis. Result: Social media marketing activities have a positive influence on brand awareness, brand image and brand loyalty. Brand awareness has a positive effect on brand image, which in turn has a positive effect on brand loyalty. Apart from that, brand awareness also has a direct positive influence on brand loyalty. Conclusion: These findings support previous literature which shows that social media plays an important role in shaping consumer perceptions of brands and building consumer loyalty.

Association Between Annual Surgeon Total Thyroidectomy Volume and Transient and Permanent Complications Muhammad Haikal, Muhammad Haikal; Tri Teguh, Tri Teguh
The International Journal of Medical Science and Health Research Vol. 2 No. 5 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/hx6sb716

Background: The association between annual surgeon total thyroidectomy volume and the incidence of transient and permanent complications has been a focal point of research in recent years, reflecting the critical importance of surgical expertise in determining patient outcomes. The literature presents a nuanced perspective on this relationship, highlighting various dimensions of surgeon experience, procedural safety, and complication rates. Literature Review: The reviewed literature collectively underscores the significant association between a surgeon's annual total thyroidectomy volume and the rates of transient and permanent complications. The studies analyzed highlight the complexity of surgical outcomes, emphasizing that higher surgical volumes are consistently linked to improved patient outcomes, particularly in terms of complication rates. Conclusion: In conclusion, the body of literature reviewed presents compelling evidence that higher annual surgeon total thyroidectomy volume is associated with reduced rates of both transient and permanent complications. This relationship not only highlights the importance of surgical expertise but also suggests that institutional practices should prioritize the development and maintenance of high-volume surgical teams to enhance patient safety and surgical effectiveness.

Association Between Cigarette Smoking and Multiple Sclerosis Sri Lestari, Sri Lestari; Rusdi, Rusdi
The International Journal of Medical Science and Health Research Vol. 2 No. 5 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/qn360m55

Background: The association between cigarette smoking and multiple sclerosis (MS) has garnered significant attention in the literature, with numerous studies elucidating the intricate relationships between tobacco exposure and MS risk, progression, and health outcomes. The exploration of these relationships has evolved over the years, revealing both the direct and indirect effects of smoking on the disease. Literature Review: The literature on the association between cigarette smoking and multiple sclerosis (MS) has revealed a complex interplay between environmental and genetic factors that significantly influence the disease's risk and progression. The studies reviewed consistently highlight smoking as a critical modifiable risk factor for MS, with evidence suggesting that both active smoking and exposure to environmental tobacco smoke (ETS) contribute to increased susceptibility and exacerbation of the disease. Conclusion: Overall, the literature consistently underscores the multifaceted role of cigarette smoking in MS, revealing that both direct and indirect exposures significantly impact disease risk and progression. The interaction between smoking and genetic predispositions, particularly concerning specific HLA genes, further complicates the understanding of MS etiology. These findings call for more focused research on smoking behaviors in MS patients and the development of tailored smoking cessation interventions to improve health outcomes for this population.

Association Between Daily Alcohol Intake and Risk of All-Cause Mortality Liliani, Liliani; Fatmawati, Fatmawati
The International Journal of Medical Science and Health Research Vol. 2 No. 5 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/gx10jv51

Background: The exploration of the association between daily alcohol intake and the risk of all-cause mortality has garnered significant attention in the academic literature, reflecting a complex interplay of health outcomes influenced by varying levels of alcohol consumption. Literature Review: The literature surrounding the association between daily alcohol intake and all-cause mortality presents a complex interplay of factors influencing health outcomes. The foundational research by (E Ronksley et al., 2011) emphasizes the ongoing debate over the cardioprotective effects of alcohol, revealing that while moderate consumption may correlate with lower cardiovascular mortality, the overall relationship with all-cause mortality remains intricate and influenced by the categorization of non-drinkers. Conclusion: In conclusion, the existing literature indicates that the relationship between daily alcohol intake and all-cause mortality is not straightforward. It is characterized by a J-shaped curve where moderate consumption may provide some protective effects, while excessive intake poses significant health risks. Methodological challenges, including the categorization of non-drinkers and the need for improved measurement of drinking patterns, underscore the complexity of this association. Public health guidelines must consider these nuances to effectively address the risks associated with alcohol consumption.

Association Between 5α-Reductase Inhibitors and Prostate Cancer Mortality Endah Lestari, Endah Lestari; Nur Fitriani, Nur Fitriani
The International Journal of Medical Science and Health Research Vol. 2 No. 5 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/rkwyyx84

Background: The role of 5α-reductase inhibitors (5-ARIs) in managing prostate cancer has been a subject of considerable debate within the medical community. The exploration of these agents has evolved significantly over the years, reflecting both their therapeutic potential and the complexities associated with their use. Literature Review: The reviewed literature presents a multifaceted examination of 5α-reductase inhibitors (5-ARIs) and their implications for prostate cancer management. The introduction establishes a framework for understanding the evolving role of these agents, emphasizing both their potential therapeutic benefits and the concerns that have emerged regarding their use, particularly in relation to prostate cancer risk and mortality. Conclusion: In conclusion, the literature collectively indicates that while 5-ARIs possess therapeutic potential in managing prostate cancer, significant concerns regarding their safety profiles—particularly their association with high-grade tumors and implications for mortality—necessitate a cautious and informed approach in clinical practice. Future research should aim to elucidate the complexities of 5-ARIs, focusing on their integration with existing treatment protocols and the need for individualized patient care.

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Indra Hadi

Contact Email profesionaljournalmedicine@gmail.com

Phone -

Journal Mail Official pt.internationalmedicaljournal@gmail.com

Editorial Address Equity Tower. 49th Floor. Sudirman Street. Special Region of Jakarta, Indonesia

Location Kota adm. jakarta selatan, Dki jakarta INDONESIA

Abstract

Abstract

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Abstract

Abstract

Abstract

Contact Name
Indra Hadi

Contact Email
profesionaljournalmedicine@gmail.com

Phone
-

Journal Mail Official
pt.internationalmedicaljournal@gmail.com

Editorial Address
Equity Tower. 49th Floor. Sudirman Street. Special Region of Jakarta, Indonesia

Location
Kota adm. jakarta selatan,

Dki jakarta

INDONESIA