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Brawijaya Journal of Urology
Published by Universitas Brawijaya
ISSN : 27214982     EISSN : 27224546     DOI : https://doi.org/10.11594/bjurology
Core Subject : Health,
Health Professions Medicine & Pharmacology
Brawijaya Journal of Urology conveys regularly the essential results of urological research and their practical and clinical relevance to a broad audience of urologists in research and clinical practice. To guarantee a balanced program, articles are published to reflect the developments in all fields of urology on an internationally advanced level. All manuscripts are subject to peer review and are judged based on their contribution of original data and ideas or interpretation. Subject areas of the journal include andro-urology, anesthesiology, biomedicine, BPH, cancer and stem cells, cell and molecular biology, female and neuro-urology, geriatrics, histopathology, internal medicine, kidney transplant, pediatric urology, pharmacology, physio-pharmacology, radiology, stones, trauma and reconstruction of urethra, uro-oncology.
Arjuna Subject : Kedokteran - Urologi
Articles 54 Documents
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A Systematic Review and Meta-Analysis of Non-Antibiotic Agents in Comparison to Antibiotic Therapies for Prevention of Recurrent Urinary Tract Infection Munawwir, Abdul; Syuaib, Achmad
Brawijaya Journal of Urology Vol. 5 No. 02 (2025): Brawijaya Journal of Urology
Publisher : Department of Urology, Faculty of Medicine, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bjurology.2025.005.02.3

Abstract

Introduction. Prolonged antibiotic usage can lead to modifications in the normal gastrointestinal tract and vaginal microbiome, which contributes to the UTI recurrence. This study aims to assess the impact of non-antibiotic therapies compared to antibiotic interventions in the prevention of recurrent urinary tract infections (UTIs). Methods. A systematic literature search was carried out from the PubMed, Google Scholar, Cochrane, and ScienceDirect databases published from 2013–2023, adjusted for inclusion and exclusion criteria. Keywords and Medical Subject Headings (MeSH) used were urinary tract infection, UTI, recurrent UTI, antibiotics, anti-bacterial agents, antimicrobial versus non antibiotic agents, probiotics, cranberries, D-mannose, vitamins, NSAID, prevention, treatment. The RevMan 5.3 program was used to analyze the risk of recurrent UTIs. Forest plot analysis was used to present relative risk estimates from individual studies and combined meta-analysis results. Results. Six studies were deemed eligible for quantitative synthesis and were included in this meta-analysis. This meta-analysis study showed a large heterogeneity, with p= 0.006 and I²= 85%. Pooled analysis using a fixed effect model showed the development of recurrent UTI was significantly lower in women with symptomatic UTI who were given non-antibiotic interventions compared to antibiotic interventions, with a relative risk of 0.75 (95% confidence interval (CI)= 0.61–0.92). This shows that non-antibiotic interventions significantly reduce the incidence of recurrent UTI compared to antibiotic interventions. Conclusion. Non-antibiotics interventions such as cranberry extract, D-mannose, NSAIDs, and herbal medicines can prevent recurrent UTI, and the results appear to be better or the same as antibiotic interventions. Meta-analyses should consider small numbers of studies with varying study designs and quality as well as small overall sample sizes.
The Profile of Urolithiasis Patient at Aeramo General Hospital: A Descriptive Research at Remote Area Gore, Andreas Perdana Putra; Wibisono, Eric
Brawijaya Journal of Urology Vol. 5 No. 02 (2025): Brawijaya Journal of Urology
Publisher : Department of Urology, Faculty of Medicine, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bjurology.2025.005.02.4

Abstract

Introduction. Urolithiasis is the fourth leading cause of kidney failure in Indonesia. Indonesia does not have a comprehensive national profile for urolithiasis. This study aims to profile the urolithiasis patient at Aeramo General Hospital, East Nusa Tenggara. Methods. This study used a descriptive design, collecting data on urolithiasis patients from non-electronic medical records from October 2020 to May 2024. Results. A total of 80 patients with urolithiasis were included in this study, 44 with kidney stones, 33 with bladder stones, and 3 with both. The largest age group was 40–60 years (50%), with a male predominance (81.25%). Most were farmers (50%) with a high school education (35%). The majority of patients smoked (63.75%) and consumed alcohol (68.75%). The most common symptom was colic pain (67.5%). Abdominal ultrasound was the primary diagnostic modality (77%). Most kidney stones measured 1–2 cm (55%), and most bladder stones were >4 cm (47%). Forty-three patients underwent surgery, while 37 did not, primarily due to financial constraints (70.3%). Conclusion. The highest incidence of urolithiasis was found in men aged 40-60 years, predominantly farmers with a high school education. Kidney stones were most common, with sizes of 1-2 cm, while bladder stones were mostly >4 cm. Financial constraints were the primary reason for refusing surgery.
Migration of an Intrauterine Device (IUD) into the Bladder: A Case Report Sani, Muhammad Mahbubi; Fadilla, Aulia Nur; Witanto, Annisa Nadhifa; Sakinah, Aulia; Virdayanti, Dian Puspita; Surahmad, Fakhri
Brawijaya Journal of Urology Vol. 5 No. 02 (2025): Brawijaya Journal of Urology
Publisher : Department of Urology, Faculty of Medicine, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bjurology.2025.005.02.5

Abstract

Introduction. Intrauterine device migration, a rare complication, refers to the movement of the intrauterine device to unintended locations, including the bladder. The following paper presents a case study illustrating intrauterine device migration into the bladder. Case. A 45-year-old woman, who has been using an intrauterine device for 15 months, was referred from the public health centre  because the intrauterine device thread was not found. She has been experiencing pain after urination for a week that hasn’t improved with medication. During a gynecological examination, no thread was found. An abdominal ultrasound examination revealed the intrauterine device was located in the bladder. Conclusion. The migration of an intrauterine device into the bladder is a rare complication that requires careful monitoring. Intrauterine device users with persistent urinary tract infection symptoms that do not improve should consider this possibility. Proper insertion procedures and regular placement assessments are essential.
Delayed Intervention of Infected Penile Siliconoma due to Unauthorized Hair Oil Injection: A Case Report Pinem, Joko Syuhada; Pariputra, Yutha
Brawijaya Journal of Urology Vol. 5 No. 02 (2025): Brawijaya Journal of Urology
Publisher : Department of Urology, Faculty of Medicine, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bjurology.2025.005.02.6

Abstract

Introduction. Penile siliconoma is an uncommon condition resulting from silicone injections into the penis, often prompted by the desire to enhance sexual performance or physical appearance. However, these procedures are associated with a significant risk of complications, including infection, granuloma formation, and penile deformation. Case. This case report describes a case of penile siliconoma in an 18-year-old male patient from a rural area who underwent penile silicone injection without medical supervision. The patient presented with thickening of the skin on the penile shaft accompanied by sores and severe pain due to self-injecting hair oil. Surgical procedures by urologists with partial excision, extraction of necrotic tissue, and reconstruction are carried out in the hope of preventing further damage to the penis. Conclusion. The case presented here underscores the critical need for patients to exercise caution and seek medical guidance before undergoing any unauthorized cosmetic procedures, particularly those involving the injection of foreign materials into sensitive areas of the body.
Correlation Between Gender, Age, and Body Mass Index with Length of Stay in Nephrolithiasis Patients Bakrun, Muhammad Iqbal Maulana; Rahman, Muhammad Aynur; Handoyo, Dimas Bintoro Kresna Yustisia
Brawijaya Journal of Urology Vol. 6 No. 01 (2025): Brawijaya Journal of Urology
Publisher : Department of Urology, Faculty of Medicine, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bjurology.2025.006.01.2

Abstract

Introduction. The increasing prevalence of nephrolithiasis in several countries in recent years has made it a serious public health concern. Three days is the typical duration of stay for nephrolithiasis treatment, so longer length of stay will burden society in various ways, especially in terms of expensive costs. This study aims to determine the relationship between the length of stay patients with nephrolithiasis at RSU PKU Muhammadiyah Mojoagung and gender, age, and body mass index. Methods. Descriptive analytic with a cross-sectional design is used in this research, applying the method of consecutive sampling. The chi-square statistical test will be used to assess the data in both univariate and bivariate formats. This research was carried out at RSU PKU Muhammadiyah Mojoagung on inpatients diagnosed with nephrolithiasis within 2023. Results. In this study, 111 patients were included, including 61 men and 50 women. Of the patients, 46.8% were between the ages of 45-65 years old, and the major criteria is non-obesity (64,9%). The patients had a stay of at least 4 days. According to Chi Square Test analysis, body mass index and length of stay have a significant correlation (p=0.012). Meanwhile, there was no correlation between age (p = 0.548) and gender (p = 0.089) with length of stay. Conclusion. Body mass index has correlation with length of stay in nephrolithiasis patients at RSU PKU Muhammadiyah Mojoagung, while gender and age has no correlation with length of stay of nephrolithiasis patients. Keywords: age, body mass index, gender, length of stay, nephrolithiasis patients
Advances in Urology: A Comprehensive Literature Review on Urolithiasis Management and Innovations Ramadhan, Reza Dwi; Wijaya, Mangkubumi Putra; Hidayat, Dzaky Ramadhan
Brawijaya Journal of Urology Vol. 6 No. 01 (2025): Brawijaya Journal of Urology
Publisher : Department of Urology, Faculty of Medicine, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bjurology.2025.006.01.3

Abstract

Introduction. Urolithiasis is a prevalent condition, affecting approximately 12% of the global population at some point in their lives, with higher incidence rates reported in industrialized nations. This condition poses significant health challenges worldwide due to its recurrence and the associated healthcare burden. Recent innovations in imaging, minimally invasive techniques, and pharmacotherapy have revolutionized the field. This review aims to explore recent updates and innovations in the management of urolithiasis, from diagnosis to therapy. Methods. A systematic search using predefined keywords in multiple databases was done. Peer-reviewed articles, clinical trials, meta-analyses, and systematic reviews focused on urolithiasis management, diagnostic techniques, therapeutic innovations, and preventive strategies were analyzed. Articles from January 2015—December 2023 were included, reviewed for its eligibility, and extracted. Results. Emerging pharmacological agents (eg. empagliflozin, thiosulfate) offer new avenues for prevention and recurrence reduction, particularly for patients with recurrent urolithiasis, although not as primary therapy. Additionally, the integration of artificial intelligence and machine learning is beginning to play a role in predicting stone recurrence and optimizing treatment plans. Conclusion. This review highlights the importance of a personalized, patient-centered approach in managing urolithiasis, emphasizing the need for ongoing research and clinical trials to further refine these innovations. Keywords: artificial intelligence, disease management, urinary stone disease, urolithiasis
A Rare Case: Vesicholithiasis with Dermoid Cyst of Bladder Nugroho, Laksono; Kholiq, Syahdat Nur
Brawijaya Journal of Urology Vol. 6 No. 01 (2025): Brawijaya Journal of Urology
Publisher : Department of Urology, Faculty of Medicine, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bjurology.2025.006.01.1

Abstract

Introduction. Ovarian dermoid cyst, also known as mature cystic teratoma (MCT), is the most common ovarian germ cell tumor in young women. Teratomas have been reported to occur in various sites and organs. Bladder teratoma is a very rare extragonadal tumor, moreover in adults. Although teratomas are known as benign lesions in childhood, they may act as malignant tumors when detected during adulthood. Case. A 64-year-old woman presented with left side low back pain and dysuria over a 6-month period. Kidney, ureter, and bladder (KUB) X-ray showed a large stone in the bladder with calcification on the left side of the abdomen. An ultrasonography revealed 4.1 cm x 3.1 cm ill-defined echogenic mass in the urinary bladder lumen. Cystoscopy revealed hair on the back of the stone. The diagnosis was made on cystoscopy and confirmed histopathologically. Complete excision was possible. The histopathology report showed a benign mature teratoma with ectodermal, mesodermal, and endodermal elements. The histopathological findings confirmed skin, adnexal structures (sweat glands, hair follicles), adipose, and fibroblastic tissue, which were consistent with those of a dermoid cyst. Conclusion. A bladder teratoma mimics the presentation of a bladder stone, clinically and radiologically. A dermoid cyst should be considered as a differential diagnosis, especially when the stone appears to be confined to the bladder wall during examination. Keywords: bladder, dermoid cys, vesicolithiasis
Potential of Preoperative Testosterone Stimulation Therapy to Reduce Complication in Hypospadias Repair: A Systematic Review and Meta-Analysis Munawwir, Abdul; Mustamar, Fikri Akbar; Palinrungi, Muhammad Asykar; Aristo, Aristo
Brawijaya Journal of Urology Vol. 6 No. 01 (2025): Brawijaya Journal of Urology
Publisher : Department of Urology, Faculty of Medicine, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bjurology.2025.006.01.4

Abstract

Introduction. The pre-operative hormone stimulation is recommended for hypospadias patients, especially those with small penis, to improve the results and outcomes of hypospadias repair. We conducted a systematic review and meta-analysis to evaluate the effectiveness of pre-operative testosterone stimulations before hypospadias repair. Methods. We performed a comprehensive search for relevant studies from PubMed, Medline, Cochrane, Proquest, and Embase from August 2000 until August 2023 . The phrases "hypospadias" and "testosterone treatment" were utilized. Only studies focusing on patients diagnosed with hypospadias were considered. This analysis exclusively included English-language papers, randomized control trials, cohort studies, and case-control studies. Case studies without comparable groups were excluded. Editorials, comments, and review articles were excluded from the study. We used the PRISMA guidelines for this systematic review and meta-analysis report. RevMan version 5.4.1 was used to analyze and evaluate the data. Results. A total of 832 patients undergoing urethroplasty were evaluated in 7 studies. A total of 372 patients were categorized into the intervention group, which received testosterone hormone therapy (parenteral, intramuscular, and topical). Patients who receive preoperative testosterone therapy have a 0.68 reduced risk of complications rate compared to those who did not (P = 0.03, I2 = 28%, CI: 0.68, OR: 0.48 - 0.96), reduced meatal stenosis (P = 0.04, OR: 0.66, 95% CI: 0.44 - 0.98, I2 = 28), reduced the risk of postoperative glans dehiscence (P = 0.0004, OR: 0.46, 95% CI (0.30-0.71), I2 = 57%), and reduced risk of fistula urethrocutaneous (P = 0.03, OR: 0.58, 95% CI: 0.36 - 0.94, I2 = 22%). Conclusion. Pre-operative testosterone stimulation can improve surgical outcomes. Complication rates, such as meatal stenosis, glans dehiscence, and fistula, showed a significant effect in patients who intervened with testosterone stimulation pre-hypospadias repair. Keywords: hypospadia, improve, outcome, repair, testosterone
Prevalence, Parental Knowledge, and Factors Associated with Delayed Treatment of Testicular Hydrocele in Toddlers at Wagir Community Health Center Anderson, Vincent Enrico; Daryanto, Besut; Nurhadi, Pradana
Brawijaya Journal of Urology Vol. 6 No. 01 (2025): Brawijaya Journal of Urology
Publisher : Department of Urology, Faculty of Medicine, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bjurology.2025.006.01.5

Abstract

Introduction. Testicular hydrocele is a genitourinary defect that can occur in males, either due to a lymphatic infection or congenital cause. Congenital testicular hydrocele is rarely reported in epidemiological data, both nationally and internationally. Additionally, if a hydrocele does not resolve naturally, it must be treated after the age of 1 year to prevent complications. This study aims to identify the incidence of congenital testicular hydrocele in several toddler health posts within the working area of the Wagir Community Health Centre, Malang Regency, East Java, Indonesia, assess parental knowledge, and analyze factors associated with delayed treatment. Methods. This descriptive and observational analytic study involved 248 male toddlers in 11 villages in Wagir, Malang Regency, East Java, Indonesia, utilizing questionnaires and physical examinations. Data was obtained passively through screening of villagers who came to the study site. Analysis was then conducted using the SPSS software by Pearson’s Chi-Square and Binary Logistic Regression. Results. From a total of 248 children, 4.44% were found with testicular hydrocele, with 1.21% cases experiencing delayed treatment. Poor knowledge about this condition was found in 81.82% of the sample. No relationship was found significant between the sociodemographic factors and health factors analyzed and the delay in hydrocele treatment (GLM, Wald Chi-Square, p = 1.000 > 0.05). Conclusion. The incidence rate of testicular hydroceles in toddlers under five years old at the integrative service post within the working area of Wagir Health Center of Malang Regency was 4.44%, of which 1.21% of cases experienced delays in treatment. Parents' knowledge of the incidence of testicular hydroceles in toddlers under five years old is still lacking. There was no significant relationship between the factors analyzed and the delay in testicular hydroceles management. Keywords: delay in treatment, epidemiology, sociodemographic factors, testicular hydrocele
Urachal Adenocarcinoma: A Case Report of Rare Tumor in Women Setya, Rindha Ilyasa; Prasetyawan, Widiyanto
Brawijaya Journal of Urology Vol. 6 No. 03 (2026): Brawijaya Journal of Urology
Publisher : Department of Urology, Faculty of Medicine, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bjurology.2026.006.03.1

Abstract

Introduction. Urachal adenocarcinoma is an uncommon malignancy that typically presents in older men, and its recognition is often delayed because early symptoms are vague. This report is distinctive because it involves a young female patient with a mucinous colon-type immunophenotype, a presentation that is unusually atypical for urachal tumors and can easily be mistaken for a gastrointestinal primary. This rare combination of demographic and pathological features makes the case clinically significant, as it highlights specific diagnostic pitfalls that are not commonly emphasized in the literature. Case. A 40-year-old woman experienced recurrent dysuria and visible hematuria for one year. CT imaging revealed a mass at the bladder dome extending toward the umbilicus, raising suspicion for a urachal lesion. Following cystoscopic biopsy suggesting mucinous adenocarcinoma, the patient underwent surgical extirpation with partial cystectomy. Histopathology accompanied by immunohistochemistry demonstrated CK7 negativity with CK20, CDX2, and β-catenin positivity, an immunoprofile characteristic of colon-type urachal adenocarcinoma. Conclusion. Early cross-sectional imaging for persistent hematuria, close attention to masses located at the midline bladder dome, and the routine use of immunohistochemical markers to differentiate urachal from colorectal adenocarcinoma are essential steps to enhance diagnostic accuracy. Incorporating these strategies may prevent missed or delayed diagnoses in similarly atypical presentations of urachal adenocarcinoma.

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