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Svāsthya: Trends in General Medicine and Public Health
Published by PT Mega Science Indonesia
ISSN : -     EISSN : 30630649     DOI : https://doi.org/10.70347/svsthya
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Svāsthya: Trends in General Medicine and Public Health is a multidisciplinary journal and it is published six times (January, March, May, July, September, and November) a year. The objective is to promote articles on general medicine, infection, public health, Global health Infection, Tropical diseases, One health and eco-epidemiology, Biomedical sciences, Epidemiology and clinical epidemiology, Molecular biology, Biology of disease and infection, Environmental health, Epidemiology and biostatistics, Disease, prevention and health promotion, Health technology and innovation, Microbiology, Pharmacological medicine, Traditional medicine, and Diseases in tropics. Svāsthya publishes original research work across all disciplines of medicine and allied sciences, related to infection, public health, global health, tropical infection, one health and diseases in tropics. The journal publishes original articles, short report, case report, review articles, systematic review - meta analysis and letters to the editor. All articles published in Svāsthya are peer-reviewed and published online for immediate access and citation.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 6 Documents
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Search results for , issue "Vol. 2 No. 1 (2025): January 2025" : 6 Documents clear
Stigmatization and social discrimination of pulmonary tuberculosis patients in Kotamobagu City, North Sulawesi: A qualitative study Akbar, Hairil; Kamaruddin, Syamsu A.; Adam, Arlin
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 1 (2025): January 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i1.79

Abstract

Tuberculosis (TB) remains a significant public health challenge, particularly in developing countries such as Indonesia. In Kotamobagu city, North Sulawesi, despite being recognized as one of Indonesia's most tolerant cities, patients with TB face persistent stigmatization and discrimination.  This study aimed to examine the social construction of discrimination against TB patients in Kotamobagu city, focusing on how these perceptions develop and persist. This qualitative study employed a constructivist paradigm and utilized Berger and Luckman's social construction theory. Data were collected through in-depth interviews and direct observations of 16 informants, including patients with TB, healthcare workers, family members, neighbors, and colleagues. The analysis was conducted via NVIVO 12 Plus software following a systematic thematic approach. The study revealed complex patterns of stigmatization and discrimination across familial, community, and workplace settings. Network analysis revealed interconnected stigmatization factors, with physical isolation emerging as a primary preventive reaction within families. Social distancing behaviors have been documented in both familial and workplace environments. This research identified multiple pathways through which stigmatization affects patients' lives, including social isolation, psychological impact, and treatment adherence. Fear of transmission has emerged as the primary driver of discriminatory behaviors, leading to various forms of social exclusion and workplace ostracism. TB-related stigma and discrimination in Kotamobagu manifest through complex social mechanisms that significantly affect patients' psychological well-being and treatment outcomes. These findings emphasize the need for comprehensive interventions that address both the structural and interpersonal aspects of stigma, particularly in workplace and family settings.
Prevalence and associated risk factors of bruise in the bovine carcass slaughtered Jimma Municipal Abattoir, Ethiopia Mohammed, Ahmednur Ali; Wolde, Radeit; Mahamed, Samatar Abshir
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 1 (2025): January 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i1.23

Abstract

Bruising bovine carcasses is a significant concern in the meat industry and affects both animal welfare and economic outcomes. This study aimed to determine the prevalence of and associated risk factors for bruises in bovine carcasses in the Jimma Municipal Abattoir, Ethiopia. A cross-sectional study was conducted from October 2022 to May 2023; 384 randomly selected cattle were examined during ante- and postmortem inspections. Data on potential risk factors, including age, sex, breed, body condition, and causes of bruising, were collected. Visual inspection, palpation, and incision techniques were employed during the postmortem examination to identify and record the prevalence, anatomical location, and severity of bruises. Statistical analysis was performed via SPSS version 16.00, with nominal regression used to determine bruise rates and chi-square tests used to assess the associations between risk factors and bruise occurrence. A 95% confidence interval was applied, and differences were considered statistically significant at p<0.05. The study revealed a 24.48% prevalence of bruising, with stick beating (8.9%) being the most common cause. The anatomical distribution of the bruises varied, with the highest condemnation rates observed in the back and loin (6.25%). Statistical analysis revealed significant differences in bruise incidence based on age, sex, and body condition (p<0.05). A high prevalence of bruising has a substantial economic impact on the local meat industry. Factors such as improper handling during transportation significantly contribute to this issue. Recommendations include implementing awareness programs for stakeholders and enhancing animal welfare measures to mitigate economic losses and improve carcass quality.
Systematic literature review on sterile injectable dates of use, stability and implications for use Dewi, I Gst A A Gangga Samala; Putri, Lucienne Agatha Larasati Nugraha; Silalahi, Lydia Devy; Dewi, I Gusti Ayu Widha Paramistya; Hapsari, Meivanti Diva; Dewa, Julio Angga Purnama; Sarayawati, Kadek Ayu Mas; Prasetya, I Wayan Sindhu Wahyu; Dewi, Ni Pande Kadek Sinta; Noviyanti, Ni Putu Rika; Sari , Putri Ayu Puspita; Rajeswari, Ni Kadek Ida; Wahyuni, Ni Luh Komang; Wulandari, Dewi; Warditiani, Ni Kadek
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 1 (2025): January 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i1.66

Abstract

Beyond-use date (BUD) is crucial for the stability of injectable preparations. However, there is a knowledge gap and a lack of information regarding BUD determination in injection preparations. Therefore, a systematic review is needed to address the BUD of injection preparations. This study aimed to provide comprehensive insights into the stability, BUD data, and associated implications for injectable preparations through a systematic literature review approach. This study employed a systematic literature review guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The inclusion criteria were research articles from national and international journals discussing the BUD of sterile injection preparations published in the last 10 years. Fourteen of the 19 articles related to BUD were selected for analysis. The analysis revealed that the stability of the 19 sterile injection preparations was significantly influenced by the characteristics of the preparation, storage conditions, and type of drug. These factors substantially affect the effectiveness and safety of drugs. Intravenous sterile injections involve several critical steps to ensure the safety and efficacy of the medications used. Adhering to BUD guidelines for intravenous injections is crucial for maintaining drug quality, which can help prevent infections or adverse reactions in patients. The stability of sterile injection preparations, which is influenced by various factors, has direct implications for BUD determination. This review highlights the importance of considering these factors when determining BUD to ensure patient safety.
Dual impact analysis of GSTT1 polymorphisms on the metformin response and cardiovascular risk: A novel integrated approach in type 2 diabetes mellitus management Dewi, Ni Luh Made Noviana
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 1 (2025): January 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i1.76

Abstract

Although genetic variations in glutathione S-transferase (GST) have been linked to type 2 diabetes mellitus (T2DM), the relationships among GSTT1 polymorphisms, metformin effectiveness, and cardiovascular risk remain unclear. This study investigated the association between the GSTT1 null genotype and the metformin monotherapy response while simultaneously assessing its impact on atherosclerotic cardiovascular disease risk. This case-control study examined 84 T2DM patients aged 30-70 years, categorized into metformin therapy responders and nonresponders. This study employed multiplex PCR for GSTT1 genotyping and utilized the pooled cohort equation for cardiovascular risk assessment, offering a comprehensive analysis of both genetic and clinical parameters. GSTT1 genetic variations were not significantly associated with metformin response (odds ratio [OR] 1.773, p=0.306) or cardiovascular risk (OR 1.086, 95% CI: 0.46-2.56, p=1.000). The analysis revealed distinct patterns in clinical parameters between the GSTT1 null and wild-type genotypes, particularly in terms of glycemic control indicators and lipid profiles, although these differences did not reach statistical significance. This study presents a novel approach by simultaneously examining both the therapeutic response and cardiovascular risk in relation to GSTT1 polymorphisms, distinguishing it from previous studies that typically focused on either aspect in isolation. These findings suggest that while genetic variations in GSTT1 may influence metabolic parameters, their direct impact on metformin effectiveness and cardiovascular risk may be more complex than previously thought.
The Isolation of mercury-resistant bacteria in the Brantas River, Malang, Indonesia Harmoko, Deni
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 1 (2025): January 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i1.77

Abstract

Mercury (Hg) is a toxic heavy metal that can originate from various sources, such as gold mining, the industrial sector, atmospheric deposition, and natural activities. Mercury contamination can cause liver, kidney, and enzyme system damage, as well as DNA damage. Because microorganisms are more sensitive to heavy metal stress than are animals and plants, the characteristics of microorganisms can be potential indicators of environmental health. This study aimed to isolate and identify mercury-resistant bacteria in the Brantas River, Malang as potential indicators of Hg pollution. Samples were isolated on nutrient agar (NA) media supplemented with 0.01 ppm HgCl₂ as a selective medium. The growing bacterial colonies were purified, and further resistance tests were carried out by adding HgCl₂ at concentrations of 0.03 ppm, 0.05 ppm, and 0.1 ppm. Bacterial isolates that survived at a concentration of 0.1 ppm HgCl₂ were then tested for sensitivity to concentrations of 0.15 ppm and 0.2 ppm HgCl₂. Bacterial isolation via HgCl₂ 0.01 ppm selective media produced 28 bacterial isolates. Further testing revealed that 19 isolates were resistant to 0.03 ppm HgCl₂, 13 isolates (0.05 ppm), and five isolates (0.1 ppm. Sensitivity tests on five bacterial isolates revealed that at a HgCl₂ concentration of 0.15 ppm, isolates RS118, RS1221, and RS1323 showed no growth inhibition, whereas at a concentration of 0.2 ppm, an inhibition zone formed for all five isolates. Although mercury-resistant bacteria were detected, this finding does not directly indicate the presence of mercury pollution in the river because bacterial resistance can be caused by various factors, including horizontal gene transfer between bacterial communities. Comprehensive testing of Hg concentrations in rivers is required to accurately determine the status of Hg pollution. This study highlights the importance of considering multiple biomarkers and environmental parameters alongside bacterial resistance patterns when assessing Hg contamination in riverine ecosystems.
Front and Back Matter for Volume 2 Issue 1, January 2025 Trends in General Medicine and Public Health, Svāsthya:
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 1 (2025): January 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Volume 2, Issue 1, January 2025 This issue consists of 5 articles contributed by 23 authors affiliated with 7 affiliations from two countries, including Indonesia (Universitas Maarif Hasyim Latif, Universitas Negeri Makassar, Universitas Mega Buana Palopo, Universitas Hindu Indonesia, Universitas Udayana), and Ethiopia (Jimma University, Jigjiga University, College of Veterinary Medicine).

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