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Trends in Infection and Global Health
Published by Universitas Syiah Kuala
ISSN : 2806646x     EISSN : 2806646x     DOI : https://doi.org/10.24815/tigh.v1i2.23580
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
TIGH publishes primary research papers, review articles, short communications and letters on the following topics: Tropical diseases Microbiology Epidemiology Public health Population health One Health Immunology Chronic diseases Surgical disease and surgical care Chemotherapy and pharmacology Maternal and child health Clinical tropical medicine
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 44 Documents
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Balance nutrition and vaccination as efforts to prevent COVID-19 in the community: A cross-sectional study Sausan Syadza; Husnah Husnah; Sitti Hajar; Iflan Nauval; RM Agung Pranata Atmaja
Trends in Infection and Global Health Vol 2, No 1 (2022): June 2022
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v2i1.23125

Abstract

The increasing cases of COVID-19 are worrying because of its rapid spread and fatality. Efforts are needed to prevent the spread of COVID-19, such as increasing immunity of the body by enforcing vaccination programs, fulfilling balanced nutritional intake, and increasing knowledge about balanced nutrition for the community. This is a descriptive cross-sectional study conducted from August 5 to 10, 2021. A cluster sampling technique was used to recruit respondents and 106 respondents were obtained. Perceptions of balanced nutrition and vaccination were assessed by a self-composed questionnaire while nutritional intake was assessed using the Food Frequency Questionnaire (FFQ). The results of the study showed that 89 respondents (84%) had a good perception of balanced nutrition and  55 respondents (51.9%) had a good perception of vaccinations. Seventy-nine respondents (74.5%) had a good eating habits while 61 respondents (57.5%) had received vaccination. Most participants (84%)  chose family/friends as sources of information about nutrition while (94.3%) chose mass media as an important sources of information on vaccination. 
Lumbar spondylosis: Does conventional X-ray still play the role? Teuku M. Yus; Iskandar Zakaria; Darma Satria; Resti Illahi
Trends in Infection and Global Health Vol 4, No 1 (2024): June 2024
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v4i1.39206

Abstract

Lumbar spondylosis is a very common complaint of severe low back pain (LBP) or lumbar disc herniation and patients often diagnosed by using radiological examination. Lumbar spondylosis is a degenerative process of the spine, but it can also result from various factors. It is often misdiagnosed as a degenerative process because it only involves the corpus vertebra, intervertebral disc, and osteoporosis of the spine. However, many other causes can lead to inappropriate treatment plans. The X-ray is believed to be a helpful tool in the initial imaging test of lumbar spondylosis diagnosis. However, further imaging tests with magnetic resonance imaging (MRI) or computed tomography (CT) scan are highly recommended. This should be noted by physicians working in rural primary and secondary healthcare facilities who might only have the X-ray to make a diagnosis of lumbar spondylosis. This article reviewed published articles on comparing X-ray, CT scan, and MRI diagnosis data of patients with lumbar spondylosis. The analysis provides insight into the role of X-ray in diagnosing lumbar spondylosis.
Early transmission dynamics of SARS-CoV-2 in Indonesia Mudatsir Mudatsir; Synat Keam; Wira Winardi; Amanda Yufika; Ali A. Rabaan; Alfonso J. Rodriguez-Morales; Kuldeep Dhama; Abram L. Wagner; Harapan Harapan
Trends in Infection and Global Health Vol 1, No 1 (2021): June 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i1.20134

Abstract

The objective of this study was to determine the transmission dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to evaluate the vigilance of the health system during the early phase of coronavirus disease 2019 (COVID-19) outbreak in Indonesia. The early epidemiology and transmission chains of COVID-19 were analyzed based on data from the Directorate General of Disease Prevention and Control of the Indonesian Ministry of Health. The results of this study shown although Indonesia is a country with a high relative importation risk of SARS-CoV-2, the first two cases of COVID-19 were identified on March 2, 2020. This relatively late date by regional standards raises the possibility of undetected cases beforehand. The first case was a foreigner citizen who visited the capital city of Jakarta and later was diagnosed COVID-19 after returning from Indonesia. One week later after the first case, 27 confirmed COVID-19 cases had been reported in Indonesia, and the majority of the cases were clustered together. Apart from the possibility of underdetection of COVID-19 cases in the country, the government has strengthened the disease surveillance system and established an outbreak preparedness system to diagnose and control COVID-19. 
Management of submandibular abscess with candidiasis complications Iip Berliananda; Benny Kurnia
Trends in Infection and Global Health Vol 3, No 1 (2023): June 2023
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v3i1.29989

Abstract

Submandibular space is part of the deep neck fascial spaces, bordered by the oral mucosa of the mouth floor on the above and the superficial layer on the deep cervical fascia on the bottom, as it extends from the mandible to hyoid bone. Submandibular space frequently involves odontogenic infections, which can cause significant mortality and morbidity. Open surgical incision and drainage are the treatment of choice for submandibular space abscesses. This is a case report of a 47-years-old female with main complaint of mass on the right submandibular that she has experienced for 2 weeks. The mass release pus which is felt flow down the throat. Physical examination revealed a soft, tender mass of 55 mm x 20 mm diameter in the right submandibular region. Oral status of the patient revealed presence of oral candidiasis too. There was no complication of trismus, swallowing pain or paralysis of the lower lip. The patient’s temperature was 38.5⁰C. Laboratory examinations showed a raised white blood cell count and slightly decreased albumin level. Intraoral swelling and redness of gingiva on the right upper middle incisor were observed. The patient was successfully treated by abscess drainage, oral antibiotics and nystatin.
Bacterial pathogens associated with eyeglasses and risks of infection: A cross-sectional study in South-West Nigeria Seyi Samson Enitan; Okeoghene Marcel Edafetanure-Ibeh; Grace Eleojo Itodo; Michael Olugbamila Dada; Grace Oluwatoyin Mensah-Agyei; Richard Yomi Akele; Stephen Olasebikan Makanjuola; Saratu Omagbemi Ajike; Nwachi Idume Ogbonna; Jamiu Monsur Olalekan
Trends in Infection and Global Health Vol 2, No 2 (2022): December 2022
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v2i2.28488

Abstract

Ocular infections have been associated with bacterial contamination of eyeglasses. This study assessed bacterial contaminants associated with the eyeglasses of the staff and students of Babcock University, Ilishan-Remo, Ogun State, Nigeria. A total of 100 participants comprising 33 males and 67 females (aged 16-76 years) were recruited for the study after obtained the written informed consents. A structured questionnaire was used to collect the demographic and clinical information. A total of 100 eyeglasses were examined for bacterial contamination using standard bacteriological methods. A one–way analysis of variance (ANOVA) and Tukey–Kramer multiple comparisons test were used to determine the differences between the bacterial loads among the eyeglasses of study participants. We found that the percentage of eyeglass lenses with unacceptable levels of contamination (105CFU/mL) and acceptable levels of contamination were 19% and 46%, respectively. The percentages of eyeglass handles with unacceptable and accepted level of contamination were 49% and 7%, respectively. Most of the isolated bacteria were sensitive to the tested antibiotics. Risk factors associated with bacterial contamination of eyeglasses were exposure to dusty environment, irregular cleaning, and poor compliance with eyeglass care guidelines. Our study further underscores the claim that eyes glasses may serve as potential vehicles for bacteria capable of causing ocular infections.
Coinciding SARS-CoV-2 infection in HIV patients with cerebral toxoplasma Dika Chandra Bintari; Paulus Sugianto
Trends in Infection and Global Health Vol 1, No 2 (2021): December 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i2.23478

Abstract

A massive and notorious impact of coronavirus disease 2019 (COVID-19) pandemic has affected communities worldwide, urging extra preventive measure, especially for individuals with comorbidities including those who are suffering from human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS). We reported a case of a 45-year-old man with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and HIV infection as well as toxoplasmosis. The patient presented to the hospital with decreased consciousness and stiffness on both hands and feet accompanied with loss of appetite, fever, and coughing. Since 2014, he had been diagnosed with HIV and undergone combined antiretroviral therapies. Toxoplasmosis was revealed by multislice computed tomography (MSCT) showing multiple rim-like lesion in cortex-subcortex of left temporal lobe along with surrounding perifocal oedema. Furthermore, the finding was corroborated by the contrasted image exhibiting rim enhancement patterns. The patient was also RT-PCR confirmed Covid-19. Following examinations, the patient received pyrimethamine with a loading dose of 200 mg. The management was continued with oral intake of pyrimethamine, clindamycin, folic acid, and vitamin B6 for maintenance dose. This case report suggests that HIV patient suffering from COVID-19 can be treated with antiretroviral therapies since the specific antivirus for SARS-CoV-2 has not yet available. We believe that this case report could contribute to more understanding on the development of clinical management for COVID-19 in HIV-positive patients.
Role of interleukin-2 in wound healing: A review study Putri Handayani; Hanifah Yusuf; Gholib Gholib
Trends in Infection and Global Health Vol 3, No 2 (2023): December 2023
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v3i2.35773

Abstract

A wound is a condition where tissue damage occurs due to disruption of tissue continuity caused by injury or surgery. Wound healing is a normal biological process in the human body which aims to restore the function and integrity of damaged tissue. In the process, wound healing involves cellular and biochemical responses, including antioxidants and cytokines, which occur locally and systemically. Interleukin-2 (IL-2) is a cytokine that plays a role in wound healing. It is produced by CD8+ and CD4+ T cells in an active state. In the wound healing process, IL-2 plays an important role in activating macrophages and natural killer (NK) cells and encouraging the proliferation of B cells and T cells. In this review, the role of the IL-2 in wound healing is discussed comprehensively.
Resuscitation goals in septic shock: fluid therapy and vasoactive drugs, an integrative review Sandro Guimarães Viveiros Rosa; Galo Guillermo Farfán Cano
Trends in Infection and Global Health Vol 3, No 1 (2023): June 2023
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v3i1.31539

Abstract

Severe sepsis and septic shock are complex syndromes with high mortality that frequently affect ICU patients. Contributions such as the Surviving Sepsis campaign have led to the issuing of guidelines for managing these patients. This manuscript aims to provide a review of state of the art using a systematic review of resuscitation and the use of vasopressors in patients with septic shock. Using MESH terms and Boolean operators, systematic research for information was carried out in PubMed in February 2023. We included 28 articles of which 18 were selected using the prism algorithm that met the inclusion criteria (analysis of septic shock, fluid resuscitation, or the use of vasopressors in septic shock in humans). In conclusion, the management of septic shock should be performed based on clear objectives to improve outcomes, for which maintenance of physiological levels of oxygenation, serum lactate, and mean arterial blood pressure are crucial.
Microbial assessment of indoor air of the applied microbiology laboratory, Nnamdi Azikiwe University, Awka, Nigeria Ezemba AS; Nwabisi CM; Udemezue IO; Ezemba CC; Osuala OJ
Trends in Infection and Global Health Vol 2, No 1 (2022): June 2022
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v2i1.24475

Abstract

Air is made up of enormous number of microorganisms mainly fungi and bacteria spores. Their estimation is important as an indication of cleanliness of any particular environment. The present study was carried out to assess microorganisms in indoor air of the Applied Microbiology laboratory of Nnamdi Azikiwe University, Awka. Prepared plates of Sabouraud Dextrose agar (SDA), Nutrient agar (NA), and Blood agar were exposed for ten minutes for culturing of microorganisms. The NA and Blood agar plates were incubated at 37oC for 24h while the SDA plate was incubated at room temperature for 48h. A total of ten (10) microorganisms were isolated from the samples. These include six (6) bacteria and four (fungal) species. The bacterial isolates include; Staphylococcus aureus, Bacillus sp., Pseudomonas aeruginosa, Escherichia coli, Streptococcus sp., and Proteus sp. The fungal isolates include Aspergillus sp., Penicillium sp., Fusarium sp., and Rhizopus sp. The most frequently isolated bacteria were Staphylococcus aureus and Bacillus sp. with 25% and 35% occurrence. Proteus sp., Streptococcus sp., E. coli, and P. aeruginosa had 20%, 10%, 5%, and 5% percentage occurrences respectively. Aspergillus and Penicillium sp. were the most frequently isolated fungal isolates with 40% and 30% occurrence respectively. Fusarium sp. and Rhizopus sp. both had 20% and 10% occurrence respectively. With this result, attention must be given to control those environmental factors which favor the growth and multiplication of microbes in the indoor air of the laboratory and air sterilization should be carried out to safeguard the health of users and workers.
A rare case of varicella zoster virus encephalitis in a 16 years old unvaccinated girl Abdul Wali Khan; Abad Khan; Muhammad Ishaq; Irfan Ullah; Marhami Fahriani
Trends in Infection and Global Health Vol 1, No 1 (2021): June 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i1.20362

Abstract

We reported a 16-year-old girl, with diffuse vesicular rashes all over the body, presented to the emergency department with altered mental status, irritability, persistent fever and one episode of a generalized tonic-clonic seizure. After thorough evaluation and investigations, the case was a varicella zoster-associated encephalitis in an unvaccinated patient. Appropriate treatment was initiated, the patient was then shifted to the critical care and subsequently discharged with no sequelae. Early diagnosis and treatment should be emphasized as they play an important role in the clinical outcome of chickenpox-associated encephalitis.

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