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Trends in Infection and Global Health
Published by Universitas Syiah Kuala
ISSN : 2806646x     EISSN : 2806646x     DOI : https://doi.org/10.24815/tigh.v1i2.23580
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
TIGH publishes primary research papers, review articles, short communications and letters on the following topics: Tropical diseases Microbiology Epidemiology Public health Population health One Health Immunology Chronic diseases Surgical disease and surgical care Chemotherapy and pharmacology Maternal and child health Clinical tropical medicine
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 44 Documents
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Management of fibrosarcoma soft palate: A rare case report Sinaga, Jakaria; Kurnia, Benny; Setiani, Lily
Trends in Infection and Global Health Vol 4, No 1 (2024): June 2024
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v4i1.38287

Abstract

Soft palate tumors can be categorized as benign or malignant, with malignant tumors being more common than benign ones. Up to 55% of intraoral tumors are found on the palate; thus, they are known as palatal tumors. Many causative or supporting factors may contribute to the development of palatal tumors, such as the long-term use of tobacco and alcohol. A final diagnosis of a palatal tumor is typically achieved through histological examination. This paper aims to present a case involving a patient diagnosed with palatal fibrosarcoma. The patient, a 39-year-old woman, was diagnosed with palatal fibrosarcoma and underwent treatment consisting of Mass Extirpation and Palatoplasty. Relevant evidence and literature were gathered through searches conducted on PubMed, Medline, and manual research. In this specific case, the surgical approach to excise the palatal tumor was determined based on factors such as its size and location. The diagnosis is based on a combination of the patient's medical history, physical examination, and further clinical assessment. Treatment for palatal tumors primarily involves surgery aimedat completely removing the tumor tissue.
Physicians’ Workload and Quality Healthcare in Indonesia Rovy Pratama; Amanda Yufika
Trends in Infection and Global Health Vol 3, No 1 (2023): June 2023
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v3i1.32363

Abstract

Indonesian law regulates that physicians might work in maximum three places. This policy results in increased workload, which might lead to burnout, affecting the quality care. This review aimed to explore how physicians’ workload affect the quality healthcare in Indonesia. We found that most Indonesian physicians worked long hours due to the current policy allowing them to work in maximum three medical centers. Vast majority of doctors in Indonesia also had to deal with abundant administrative works, especially since the implementation of Jaminan Kesehatan Nasional (JKN). Excessive workload increased work-related stress and job dissatisfaction, which eventually increased physician’s burnout. All these results in poorer quality healthcare. One of the solutions is to regulate physicians to only work at one healthcare facility (Mono-loyalty). However, a careful consideration and thorough preparation to adopt this policy is warrant.
Profile of antibiotic susceptibility test of bacterial pathogens isolated from the hands of university students in Nigeria John Cletus Ihongbe; Salter Oluseun Aramide Adeyemo; Seyi Samson Enitan; Michael Olugbamila Dada; Oluchi Gladys Ofem; Effiong Effiong Joseph; Chinenye Alaezi Okorochi; Nwachi Idume Ogbonna
Trends in Infection and Global Health Vol 2, No 2 (2022): December 2022
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v2i2.29972

Abstract

The aim of this study was to assess bacterial contaminants isolated from hands of undergraduate students of Babcock University, Nigeria. A total number of 200 students (100 males and 100 females) were randomly recruited and hand swabs were collected and inoculated on MacConkey and chocolate Agar. The biochemical tests were conducted to identify the bacterial isolates and antibiotic susceptibility testing was carried out using the disc diffusion method. Out of the 200 participants examined, bacterial contaminants were recovered from 154 (77.0%). The most frequently isolated organisms were Staphylococcus aureus (32.5%), followed by Escherichia coli (26.6%), coagulase negative Staphylococcus (20.8%) and then Klebsiella pneumoniae(20.1%). The antibiotic sensitivity showed that all coagulase negative Staphylococcus isolates were sensitive to ceftriaxone, levofloxacin, ciprofloxacin, imipenem, ofloxacin and azithromycin, but less sensitive to cefuroxime (50.0%) and amoxicillin (60.0%). S. aureus was sensitive to levofloxacin, ofloxacin, gentamycin and azithromycin while for Gram negative bacteria, E. coli was 100% sensitive to levofloxacin, imipenem, cefuroxime, ofloxacin, and ampiclox, but less sensitive to amoxicillin (20.0%). Klebsiella pneumoniae was sensitive to ceftriaxone and gentamycin, 100% and 90.0%, respectively, but less sensitive to amoxicillin (20.0%). In conclusion, some bacteria exist on the hands of undergraduate students of Babcock Students with varied antibiotic susceptibility patterns and therefore institutional implementation of hand hygiene practices should be implement among students in the university.  
Chronic lymphocytic leukemia in a farmer and vegetable seller: Associated with exposure of multiple work-related hazards? Dewi S. Soemarko; firly ratsmita
Trends in Infection and Global Health Vol 1, No 2 (2021): December 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i2.21582

Abstract

There are several risk factors associated with the incidence of chronic lymphocytic leukaemia (CLL), namely genetic factors, smoking, and occupational exposure to chemicals. We highlight a possible association of a CLL case and the occupational. We reported a case of CLL patient, a 69-year-old man, who had been working as a vegetable seller and a chili farmer since 15 and 4 years ago, respectively. The patient was diagnosed with CLL three months prior to admission and had a history of three times blood transfusions. The patient only complained of paleness and weakness without any specific symptoms. No swelling of the lymph nodes, hepatomegaly, or splenomegaly was found. As a vegetable seller and chili farmer, the patient was exposed to five hazards, physical, chemical, biological, ergonomic to psychosocial. Therefore, it is necessary to analyse whether there was an association between the patient's work and the current CLL. To diagnose occupational diseases, several steps are needed. In this patient, one of the risk factors that could lead to CLL was exposure to chemicals such as pesticides. However, information regarding the content of pesticides used was unclear and there were no results obtained from pesticides biomarker examination that might cause the disease, making it difficult to establish a definitive diagnosis of work-related cause. The patient could be advised to have biomarkers of pesticide substances checked, which requires control of farmers and vegetable sellers who might have been exposed to pesticides. The control mechanism might be started from elimination, substitution, engineering, administration, and use of personal protective equipment. A control mechanism is necessary to prevent the entry of contaminants into the body, especially through inhalation, oral, and dermal pathways. It is recommended to examine for biomarkers of pesticides containing organophosphates, organochlorines, or carbamates to determine the chronic effects on the accumulation of these chemicals that might cause CLL.
Aging-related skin microbiome in healthy Asian women Dian Rahmayani; Winda Yulia; Zulkarnain Zulkarnain
Trends in Infection and Global Health Vol 3, No 2 (2023): December 2023
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v3i2.35775

Abstract

The skin, an environment for the microbiome, has different physical, chemical and physiological states depending on the its site and the individuals. Because of these differences, the community and ecosystem of the microbiome are different for each individual. The differences in these microbiome ecosystems are also determined by their genetic properties, such as demographics, gender, age, race, level of hygiene, lifestyle, and physical injuries. Little is known about the association of microbiome and aging in Asian population. This review aim to gather current knowledge on aging-related skin microbiome in Asian women, namely Korean, Chinese and Thai. Changes in microbiome was found to be not only age-related but also ethnicity-associated. Future study with larger sample size is warrant to further elucidate the association of aging and skin microbiome in Asian female population.
The use of herbal medicines by the elderly in rural area in Indonesia: A cross-sectional study among Acehnese Suryawati Suryawati; Sarah Firdausa; T. Hidayat Syah; Vera Dewi Mulia; Hijra Novia Suardi; Zahratul Aini; Fauzul Husna; Hafni Andayani
Trends in Infection and Global Health Vol 3, No 1 (2023): June 2023
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v3i1.31438

Abstract

The use of herbal medicines has become increasingly popular worldwide. Elderly has been associated with higher consumption of many medications, including herbal medicines. However, there is a lack of documentation of medicinal herbs use among Acehnese population. Our study aimed at evaluating the profile of herbals use among the elderly population in a rural area of Aceh Province, Indonesia. A cross-sectional study was conducted from October to November 2021 in Nagan Raya Regency of Aceh. To collect information on the use of herbs, a set of structured questionnaires was utilized. The data were presented in percentage (%). A total of 100 respondents were included comprising 54.0% female and most of the respondents aged between 60–64 years (43.0%). The largest percentage of the participants made their own herbal medicines (45.0%) and used them routinely as a habit (36.0%). About 75.0% of the elderly felt better and almost all of them (96.0%) reported no adverse reaction following herbs consumption. A total of 39 plant species were used by the respondents with Annona muricate L. was the most frequently used medicinal plant (16.0%) and leaves were the most commonly used parts (68.4%). Most of the herbs were prepared through boiling and squeezing (32.6%), and mainly used in the form of a drink (77.3%). Cough treatment with herbs made up 19.3%, followed by hypertension (18.0%), flatulence (7.6%), dyspepsia (5.8%), and fever (5.8%). Our investigation revealed consistency in the use of some medicinal herbs in the present study with published experimental data. However, since elderlies are often considered vulnerable individuals, the practice of herbal self-remedies among this population should be well-monitored.
Characteristics of referred patients to the Emergency Department in Aceh before COVID-19 pandemic Meilya Silvalila; Nurul Huzaifi; Shefina Pyeloni Harnold; Reza Akbar
Trends in Infection and Global Health Vol 2, No 1 (2022): June 2022
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v2i1.25687

Abstract

As an important entry point for referral patients, the management of the Emergency Department to care and implement the best possible treatment are required. The Emergency Department of provincial hospital plays a vital role as a referral hospital of all district-level hospitals to provide initial treatment for a broad spectrum of illnesses and injuries. In Aceh, many referral issues were encountered at the Emergency Department of Dr. Zainoel Abidin Hospital, which categorized the referral patient's condition that was considered to improve clinical care to patients referred. This quantitative study aims to determine the characteristics of patient referral and the referral issues encountered at the Emergency Department of dr. Zainoel Abidin. In total, 1674 patients were recruited using the purposive sampling method from April to June 2019. The results showed that most referral patients arrived at the Dr. Zainoel Abidin Hospital emergency room during the night and very few arrived in the morning. Most patients arriving at the Emergency Department of Dr. Zainoel Abidin Hospital at night were from Aceh Singkil and Gayo Lues. Meanwhile, patients from Aceh Besar, Aceh Jaya, Banda Aceh, Pidie, and Pidie Jaya mostly arrived at the Emergency Department Dr. Zainoel Abidin Hospital during the afternoon. Most patients from Sabang and Simeulu came in the morning. The most commonly referred patients were adult and elderly patients, aged 46-65 years. Most of the patients had been treated in the daycare unit at the previous hospitals with the longest hospital stay was 36 days before being referred to Dr. Zainoel Abidin Hospital. Head injuries and strokes were the most frequent diagnosis led to Emergency Department Dr. Zainoel Abidin Hospital. Furthermore, our study found that 51% of the referral care system issue was that the patient did not arrive at the Emergency Department of Dr. Zainoel Abidin Hospital after being confirmed to be referred through telephone. Most of this issue happened in June for an unknown reason. At the same time, another 23% was due to the unavailability of intensive care.
COVID-19 with acute hepatitis A virus co-infection in a fully-vaccinated individual: a case report Masra Lena Siregar; Rabid Yahya Putradasa; Arini Nisaul; Suheir Muzakkir
Trends in Infection and Global Health Vol 1, No 1 (2021): June 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i1.22416

Abstract

In a developing country with varying degree of public hygiene and sanitation, prevalent infectious diseases such as hepatitis A (HAV) could add to the burden of infection during coronavirus disease 2019 (COVID-19) pandemic and complicate its gastrointestinal and hepatic manifestation. Here we present a case COVID-19 with acute hepatitis A virus co-infection in a young female with fever, joint pain, non-productive cough, loss of smell, abdominal discomfort, darkened urine, and pale loose stool before admission. The significant finding was slightly icteric sclera, hepatomegaly with tenderness in the epigastrium and right upper quadrant, increase in aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, total bilirubin, C-reactive protein and, D-dimer. A naso-oropharyngeal swab examination for SARS-CoV-2 infection was positive, and IgM anti-HAV was reactive with a total anti-HAV titer 60 mIU/mL. Subsequently, she was hospitalized for 14 days, successfully recovered; her symptoms resolved and her level of liver enzymes back to normal, and she was discharged for self-isolation at home. RT-PCR for SARS-CoV-2 infection came back negative 7 days later. In light of the pandemic, physicians need to raise suspicion of co-infection of COVID-19 with other hepatitis viruses in cases with gastrointestinal and hepatic manifestation. A marked increase in liver enzyme may warrant further testing for hepatitis viruses where such infection should be suspected.
Staphylococcus hominis and facial aging Rahmayani, Dian; Yulia, Winda; Zulkarnain, Zulkarnain; Odigie, Joan
Trends in Infection and Global Health Vol 4, No 1 (2024): June 2024
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v4i1.39739

Abstract

Skin aging is a natural process that manifests prominently in facial skin. Key indicators of facial skin aging include sagging skin, wrinkles, hyperpigmentation, and decreased hydration. Understanding these signs is crucial for both clinical and cosmetic applications. This review focuses on the skin microbiome, with a particular emphasis on Staphylococcus hominis, a commensal bacterium that plays a significant role in the skin aging process. The objective of this article is to consolidate scientific evidence from various studies to elucidate the relationship between the skin microbiome, especially S. hominis, and the manifestations of skin aging. Through this comprehensive review, we aim to provide insights into the potential of targeting the skin microbiome for anti-aging interventions and enhance our understanding of the complex interactions between skin health and its microbial inhabitants.
Aeromonas veronii an emerging pathogen: A brief review Henry Junior Parra-Vera; Galo Guillermo Farfán-Cano; Dayci Colombia Buele-Chica
Trends in Infection and Global Health Vol 3, No 2 (2023): December 2023
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v3i2.34098

Abstract

Aeromonas veronii, a Gram-negative bacterium, thrives in aquatic environments and is linked to diseases in animals and humans. The primary aim of this review was to provide an extensive description of A. veronii as an infectious agent, focusing on its microbiological attributes, pathogenesis, distribution, virulence, and antimicrobial resistance. An exhaustive review of the available medical literature was conducted. Theoretical sources were scrutinized to determine the taxonomic and microbiological properties of A. veronii. The pathogenic characteristics of the bacterium were examined, with a special emphasis on virulence factors, epidemiology, zoonotic potential, and antimicrobial resistance. Additionally, pertinent data regarding the geographic distribution of A. veronii from various origins, encompassing the environment, farm animals, and clinical cases in humans, were synthesized. This investigation illuminated the significant microbiological traits of A. veronii, including its adaptability to various environmental conditions and its ability to persist in crucial sources of infection, such as poultry feces and processing water. In addition, specific A. veronii strains, along with other Aeromonas species, have been identified as emerging pathogens in foodborne disease outbreaks in developing nations, accentuating the importance of rigorous hygiene measures in food production and handling. The study underscored the opportunistic nature of A. veronii in immunocompromised individuals, emphasizing the necessity for active surveillance and stringent hygiene practices to mitigate exposure and transmission among vulnerable populations. Furthermore, the relevance of the virulence factors of A. veronii, including biofilm formation and the presence of antimicrobial resistance genes, was emphasized, underscoring the importance of ongoing research to understand and combat antimicrobial resistance in this bacterium.

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