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Ahmad Shafwan S. Pulungan
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Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Negeri Medan Jl. Willem Iskandar Psr V Medan Estate, Sumatera Utara
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JBIO: jurnal biosains (the journal of biosciences)
Published by Universitas Negeri Medan
ISSN : 24431230     EISSN : 24606804     DOI : https://doi.org/10.24114/jbio.v6i1
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology
Jurnal Biosains (JBIO) features works of exceptional significance, originality, and relevance in all areas of biological science, from molecules to ecosystems, (ie genetic, microbiology, ecology, biosystematic, biostatistic) including works at the interface of other disciplines, such as chemistry, medicine,physic and mathematics. We also welcome data-driven meta-research articles that evaluate and aim to improve the standards of research in the life sciences and beyond. Our audience is the international scientific community as well as educators, policy makers, patient advocacy groups, and interested members of the public around the world.
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 7 Documents
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Search results for , issue "Vol 8, No 1 (2022): JBIO: jurnal biosains (the journal of biosciences)" : 7 Documents clear
THE INFLUENCE OF SHIFTWORK ON LIVER DYSFUNCTION OF WORKERS AT INALUM COMPANY KUALA ANJUNG, NORTH SUMATERA Royman S Panjaitan; Sartini Sartini; Ida Fauziah
JBIO: jurnal biosains (the journal of biosciences) Vol 8, No 1 (2022): JBIO: jurnal biosains (the journal of biosciences)
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v8i1.32398

Abstract

This study was conducted to determine the effect of the shiftwork system on liver dysfunction workers characterized by elevated of liver function enzymes SGOT (Serum Glutamic Oxaloacetic Transaminase) and SGPT (Serum Glutamic Pyruvate Transaminase) in the employees at Inalum Company at Kuala Tanjung. The research was derived from primary and secondary data. Primary data was conducted by a direct examination of SGOT and SGPT enzymes at liver (expressed in Unit units per liter of blood serum (U/L). The secondary data obtained from the Smelter Public Relations. All data obtained were analyzed using paired t-test analysis techniques by comparing SGOT and SGPT enzymes between 324 shift and non-shift workers. Results showed significant differences in SGOT and SGPT among 162 employees with shift work from the average SGOT period I 34.4 U/L rise to 42.0 U/L in period II and the average SGPT at period I was 62.5 U/L to 73.4 U/L in period II. While the average SGOT and SGPT among 162 non-shift employees also increased, but still in normal limit (SGOT <35 U/L and SGPT <45 U/L). Employees with a shift work system experienced an elevated of SGOT and SGPT which resulted impact on liver dysfunction caused by fatigue and no resting time. Whereas non-shift employees experienced an elevated of SGOT and SGPT but have no affect liver dysfunction.
BIODIVERSITY REVIEW FROM EVOLUTION AND ITS INFLUENCES ON CLIMATE Jamilah Nasution; Ferdinand Susilo; Nurmaini Ginting; Radiansyah Hadi Chandra
JBIO: jurnal biosains (the journal of biosciences) Vol 8, No 1 (2022): JBIO: jurnal biosains (the journal of biosciences)
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v8i1.33011

Abstract

Biodiversity refers to the variety of organisms, including genes, species, and ecosystems in a given area. Biodiversity plays an important role in evolutionary processes and in maintaining the balance between the biosphere ecosystem and biological systems. Climate change is equally important to contribute to the sustainability of biodiversity. Factors causing ecosystem damage include human population, habitat conversion and transformation, overexploitation, invasive species, pollution, and climate change. By stopping the rate of loss of biodiversity that is occurring in the world, it will automatically invest in the survival and welfare of every human being.
MANUFACTURE OF ACTIVE CARBON TABLETS FROM SALACCA (SALACCA ZALACCA) SEEDS AS ANTI-DIARY TREATMENT Christica Ilsanna Surbakti; Bunga Rimta Barus
JBIO: jurnal biosains (the journal of biosciences) Vol 8, No 1 (2022): JBIO: jurnal biosains (the journal of biosciences)
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v8i1.32356

Abstract

Salak seeds (Salacca zalacca) used to be considered as waste that is not useful and just thrown away. Now with advances in technology, some of the by-products of salak seeds can be processed into more economical products such as activated carbon which can be used as a treatment for diarrhea because it acts as an adsorbent. The method used to make activated carbon tablets is the wet granulation method with 2 kinds of formulas. The physical properties of the tablets were tested, including weight uniformity, hardness, friability and tablet disintegration time. Pharmacological testing on this activated carbon tablet which is used for the treatment of diarrhea will be tested on rats given orally and observed for 3 days.and the maximum result is the addition of 250 mg of activated carbon where the weight of the feces is reduced by up to 30%
pH, WATER AND FAT CONTENT ANALYSIS OF INTEGRATED FORMULATION OF HERBS AND SPICES IN TYPICAL SIMALUNGUN “TINUKTUK” Marini Damanik; Risti Rosmiati; Tyas Permatasari; Syarifah Ayuni; Tia Aulia Surbakti
JBIO: jurnal biosains (the journal of biosciences) Vol 8, No 1 (2022): JBIO: jurnal biosains (the journal of biosciences)
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v8i1.33534

Abstract

The use of spices and herbs is a functional food product that is believed to be efficacious for health and can increase the body's immunity or is usually called an immunomodulator. Tinuktuk has very good properties for the health of the body. By warming the body and also counteracting free radicals with antioxidant activity. This study aims to determine the optimization of the dose of the main components of red ginger and black pepper to produce Tinuktuk with high nutritional value by preparing with an oven. The process in this method uses the percentage of the ratio variation of 70:30, 60:40, 50:50, 40:60, and 30:70. Then, the quality of the tinuktuk was tested, namely: the pH, moisture and fat content. The oven method showed that the pH values from the ratio of 70:30, 60:40, 50:50, 40:60, and 30:70 were 6.15, 6.25, 6.25, 6.25, 6,3, respectively. Beside, for the water content was 56.61%, 54.68%, 54.065%, 49.395%, 45.265% and fat content was 15.52%, 18.35%, 15.46%, 19.39%, 16.50%.@font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:-536869121 1107305727 33554432 0 415 0;}@font-face {font-family:Rosarivo; panose-1:2 11 6 4 2 2 2 2 2 4; mso-font-charset:0; mso-generic-font-family:auto; mso-font-pitch:auto; mso-font-signature:0 0 0 0 0 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; text-align:justify; line-height:115%; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:IN; mso-fareast-language:EN-ID;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; mso-ansi-language:IN; mso-fareast-language:EN-ID;}.MsoPapDefault {mso-style-type:export-only; text-align:justify; line-height:115%;}div.WordSection1 {page:WordSection1;}
EFFECTS OF PHYSICAL ACTIVITY Fast Interval Training AND PROVISION OF MELINJO SKIN EXTRACT (Gnetum gnemon) ON EXPRESSION OF URAT1 TRANSPORTER, GLUT9 AND SGLT2 IN HYPERURICEMIA INSULIN RESISTANCE Armansyah Maulana Harahap; Yetty Machrina
JBIO: jurnal biosains (the journal of biosciences) Vol 8, No 1 (2022): JBIO: jurnal biosains (the journal of biosciences)
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v8i1.29105

Abstract

Observational studies and randomised controlled studies suggest Increased prevalence of hyperuricemia is a decrease in physical activity and high consumption of purines. Disruption of urate reabsorption causes changes in the main functions of transporter proteins in the proximal tubule membrane. One of them is the intake of URAT1 and efflux by GLUT9 and also for the expression of SGLT2. Insulin resistance causes disturbances in glucose uptake in (SGLT2) and urate. The mechanism of glucose uptake can be mediated by exercise and effect of melinjo skin extract. A Technical Expert Panel (TEP) of 2 medical specialist and expertise of disorder the urinary system performed the review using the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) model. The TEP planned a research on PubMed selecting “Hyperuricemia” as MeSH (Medical Subject Headings) term adding to PubMed Search Builder the terms “Exercise” and “Melinjo skin extract”. TEP is considered for eligibility articles published within the last 10 years, including original research, in particular in vitro studies, and animal and clinical studies in English. Results: Of the 90 identified studies, TEP included 15 studies, 8 animals, and 4 clinical studies and 3 Review. Conclusion: Our scoping review describes and summarizes the important role of exercise and the effect of melinjo peel extract in modulating uric acid levels, Insulin resistance and up-and-down regulation of urate transportersKeyword: Hyperuricemia, URAT1, GLUT9, SGLT2, Exercise
THE IDENTIFICATION OF ANTIBACTERIAL COMPOUNDS IN CLOVE STEM EXTRACT (Syzygium aromaticum) AND ITS EFFECTIVENESS IN INHIBITING THE GROWTH OF Escherichia coli Yunita Diyah Safitri; Ana Amalia; Fatimah Fatimah; Afidatul Muadifah
JBIO: jurnal biosains (the journal of biosciences) Vol 8, No 1 (2022): JBIO: jurnal biosains (the journal of biosciences)
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v8i1.28089

Abstract

Clove plants usage in daily life is very diverse, such as kitchen spices, mixtures of various drinks, and medicines. Clove is a spice plant that contains clove oil which is known as an antibacterial agent. The clove stem has a fairly high clove oil content, but this is not widely known by the public. Clove oil is known to have the ability as a fungicide, bactericide, insecticide, and nematicide. The purpose of this study is to identify antibacterial compounds and the effectiveness of clove stem extract on the growth of Escherichia coli. We used GCMS (Gas Chromatography Mass Spectrometry) analysis to identification antibacterial compounds. Antibacterial activity test using paper disc method by measuring the diameter of the inhibition zone formed from clove stem extract at doses of 30%, 50%, and 70% against Escherichia coli. The results of the study were analyzed using ANOVA with significance (p<0.05). The identification of the active compound showed 13 kinds of compounds were found with the dominant compound was alpha-pinene. The results of the antibacterial test showed the antibacterial activity of clove stem extract at doses of 30%, 50% and 70% with inhibition zones formed 12 mm, 12.7 mm, and 14.1 mm respectively. 
Coliform AND Escherichia coli TESTS IN THE AIR OF THE WELLS OF THE VILLAGE SIDO MAKMUR KUALA DISTRICT LANGKAT DISTRICT Wulandari Wulandari; Mhd Yusuf Nasution; Hudson Sidabutar; Ahmad Shafwan S Pulungan
JBIO: jurnal biosains (the journal of biosciences) Vol 8, No 1 (2022): JBIO: jurnal biosains (the journal of biosciences)
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jbio.v8i1.18755

Abstract

Dug well water is a source of clean water that is used by 99.39% of the residents of Sido Makmur Village, Kuala District, Langkat District to meet their daily needs. The majority of people who have cow pens around dug wells trigger the importance of conducting microbiological water quality research, given the existence of dug wells that are very vulnerable to cow manure contamination. Therefore the research sample was taken based on the distance of the dug well with a cattle pen that is less than 5 meters. Five samples from Inpres Hamlet, Petak Dua Hamlet, Handayani Hamlet, Sidorejo Hamlet and Mandailing Hamlet were tested using the Most Probable Number (MPN) method in the North Sumatra Province Health Laboratory, to determine the presence of Coliform and Escherichia coli through the estimation test, assertion test , and test the completeness and coloring of grams. Then a biochemical reaction test is performed to confirm the presence of Escherichia coli. The results showed that all dug well water samples with sample codes ASG 01, ASG 02, ASG 03, ASG 04 and ASG 05 were positively polluted by Coliform through assertion tests with total Coliform exceeding the 80% threshold and below the threshold of 20% based on Minister of Health Regulation No. 416 / MENKES / PER / IX / 1990 concerning Requirements and Supervision of Water Quality. Then there is also the content of Escherichia coli in the five samples which exceeds the established threshold, the positive results of E.coli have also been strengthened through the results of gram staining and biochemical reaction tests. Therefore the dug well water samples tested are not feasible or do not meet the microbiological quality requirements for clean water.

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