cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Juvita Herdianty
Contact Email
j.herdianty@gmail.com
Phone
085236539600
Journal Mail Official
sjpstrada@gmail.com
Editorial Address
Jl. Manila No.37, Tosaren, Kec. Pesantren, Kota Kediri, Jawa Timur 64123, Indonesia.
Location
Unknown,
Unknown
INDONESIA
Strada Journal of Pharmacy
Published by Universitas Strada Indonesia
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 83 Documents
 3   4   5   6   7 
Formulation and Determination of Sun Protection Factor (SPF) of Sunscreen Gel Preparations Containing Epigallocatechin Gallate (EGCG) Using the Spectrophotometric Method Oppy aesaiw
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.123

Abstract

Long-term exposure to the sun causes various kinds of abnormalities in human skin so it requires skin protection from the outside. Sunscreen is a cosmetic therapy that can shield the skin and face against UV radiation, including the potential to induce accelerated ageing, sunburn, and skin cancer. Tea leaf-derived polyphenol compounds, particularly EGCG, have the most potent and plentiful antioxidant action. The objective of this work is to investigate the impact of variations in epigallocatechin gallate (EGCG) levels on the physical properties and effectiveness of sunscreen gel. This study used an experimental design with four EGCG gel formulas (negative control (0%), F1 (0.1%), F2 (0.2%), F3 (0.4%)) and tested with a UV-Vis spectrophotometer with the resulting absorbance calculated using the Mansur formula.The results showed that the SPF value increased with increasing EGCG concentrations (negative control, F1, F2, F3, positive control: 18.94 (moderate), 22.55 (moderate), 29.10 (moderate), 41.58 (high), 48.11 (high)). The highest SPF value on Formulation 3 indicates a high level of sunscreen capability. EGCG gel with a concentration of 0.4% has good physical characteristics (slightly thick texture, odorless, transparent white color, homogeneous, pH 6.57, adhesion 3.30, diffusion 6.36) and the highest SPF value (41.58). The statistical test using Kruskall-Wallis followed by the Man-Whitney test showed a significant difference in a p-value of 0.05.
Variations in the concentration of magnesium stearate as a lubricant in the evaluation test results of paracetamol tablet preparations Agnes Widian; Dimas Bagus Cahyo
Strada Journal of Pharmacy Vol. 1 No. 2 (2019): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i2.125

Abstract

Tablets are an oral drug preparation that can be formulated with or without additional substances. This preparation has many advantages, one of which is that it is practical to use and can be produced on a large scale. Tablets are produced using 3 methods, namely dry granulation, wet granulation and direct compression. Each manufacturing method must be adapted to the tablet material to be printed. So it is necessary for formulators to know the characteristics of the materials to be used.Tablet production involves excipients or additional substances which have an important role. Excipients are one of the considerations in preformulation studies to determine the right characteristics and quantities to produce tablets that meet the requirements. One of the excipients in tablet formulation is a binder. So far tablet binders are divided into 2 types, namely natural polymer binders and synthetic polymer binders. Additional materials play 2 important roles in making tablets, one of which is the binder. The binder is intended to provide tablet compactness and durability so that the binder guarantees the integration of several powder particles into a granulate (Oktavia, 2011). Granulation is a process of increasing the size of small powder particles that are bound together to become large ones that can flow freely. The purpose of granulation is to make the mass flow freely, compact the mixture of ingredients, create a uniform mixture that does not separate, improve the compressibility characteristics of the active substance, control the speed of release of the active substance from the dosage form, reduce dust and improve the appearance of the tablet (Lachman, 1994). Observation of the results of evaluating the physical quality of the preparation includes organoleptic tests, hardness test, brittleness test, disintegration time test and weight uniformity test. The results of this research based on the friability test, the F1 result was 0.74%, fulfilling the requirements of the tablet friability test, namely, no more than 0.8% loss of the total mass of the FI 3rd edition tablet. 4. The results of the tablet uniformity test show that there is not a single tablet whose weight deviates from column A, namely more than 5% and there is not a single tablet whose weight deviates from column B, namely more than 10% from the average weight in F1. All tablets in FI have a uniform tablet weight with no deviation so that FI complies with the specified range requirements.
Analysis of Patient Satisfaction with Pharmaceutical Services at the Northern Region Primary Health Center of Kediri City in 2019 Hanie Kusuma Wardan
Strada Journal of Pharmacy Vol. 1 No. 2 (2019): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i2.126

Abstract

Pharmaceutical services are an integral component of the health care system at primary health center. One of the quality indicators in pharmaceutical services at the Northern Region Primary Health Center of Kediri City is patient satisfaction. This study aims to analyze patient satisfaction with pharmaceutical services at the Northern Region Primary Health Center of Kediri City in 2019. Using a cross-sectional design, the study involved 110 respondents selected through accidental sampling. Data were collected using a standard questionnaire from Regulation of the Minister of Health of the Republic of Indonesia No. 74 of 2016 and analyzed using the Community Satisfaction Index method. The results showed a Community Satisfaction Index value of 3.19 (equivalent to 79.66 after conversion), indicating a satisfaction level of "Satisfied" with a service quality of "B". The service element with the highest score was the friendliness of the pharmacist/ pharmacy technician (3.40), while the availability of written educational materials received the lowest score (2.96). This study concludes that although pharmaceutical services at the Northern Region Primary Health Center of Kediri have reached a good level of satisfaction, there are still some aspects that require improvement, especially in terms of physical facilities and the provision of health information.
Addition of Talcum to the formulation of clindamycin capsule preparations on evaluation test results Ivonder; Savira Sandriansyah
Strada Journal of Pharmacy Vol. 1 No. 2 (2019): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i2.127

Abstract

Medicines are all single ingredients or mixtures that are used by all living creatures internally and externally, to prevent, alleviate or cure disease. In general, according to the dosage form, drugs are divided into 3 types, namely liquid preparations, semi-solid preparations and solid preparations. In this practicum we made a solid dosage form, namely capsules (Ansel, 1989). Capsules are solid preparations consisting of medication in a hard or soft shell that can dissolve (Fatmawaty et al, 2012). Hard capsules are usually made from gelatin which consists of the capsule shell, the body and the capsule cap. The two parts of the capsule cover will cover each other when brought together and the cover will cover the body of the capsule (Ansel, 2005). Clindamycin inhibits most gram-positive cocci and most anaerobic bacteria, but cannot inhibit aerobic gram-negative bacteria such as 33 Haemophilus, Mycoplasma and Chlamydia (Ministry of Health, 2011). The mechanism of action of clindamycin is the same as erythromycin. Clindamycin is mainly given to treat infections caused by anaerobic bacteria, such as Bacteriodes fragilis bacteria which often cause abdominal infections caused by trauma (Katzung, 2012). Considering the importance of knowledge about antibiotic drugs such as clindamycin, a good and correct method for formulating solid capsule dosage forms has been developed and what must be taken into account when making them. Based on the test results, F1 3.44 seconds, F2 3.76 seconds, F3 3.24 seconds, the flow speed of these three formulas meets the flow speed requirements, namely flow speed ≥ 10 g/second. The flow speed of the three formulas is in the good category, namely 2-10 g/sec which is said to be very good while it is said to be good. The flow speed is good because Aerosil has a very small and fine particle size. Apart from being an absorbent, aerosols are also able to improve flow properties by reducing friction between particles and by averaging test results from angles of repose F1 45°, F2 43° and F3 53°.
Physical Stability Test of Ethanol Extract Ointment Preparation of Ambon Banana Peel (Musa acuminata cavendish subgroup) Rafelin Putri Herlambang
Strada Journal of Pharmacy Vol. 1 No. 2 (2019): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i2.129

Abstract

Medical plants found in nature, one of which is the banana plant. Bananas have many benefits but have not been widely used by the public. contains tannins, saponins and flavonoids found in banana hump reported to contain vitamin C, vitamin A, protein and fat which work in the process of wound healing. Ointments are the most suitable preparation for the treatment of burns because they function as carriers of medicinal substances for use on the skin, as lubricants and skin protectors so as to prevent contact of the injured skin surface with external stimuli. Ointment is a semi-solid preparation that is easily applied and used as an external medicine. This study aims to look at the physical stability of the formulation of sakep preparation of ethanol extract of ambon banana peel at concentrations of 10%, 15%, 20%. Evaluation of physical properties includes organoleptic tests, homogeneity, pH, spreadability and adhesion. The test results showed that the best formulation was formulation 3, namely the kapok banana peel extract ointment with a concentration of 20% which met the requirements for pH testing, spreadability test and adhesion ability.
Antibacterial Activity Test of Ethanol Extract of Spoon Leaves (Plantago major. L)Against Salmonella typhi Refaldi Shaputra
Strada Journal of Pharmacy Vol. 1 No. 2 (2019): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i2.130

Abstract

Typhoid is a bacterial infection disease of Salmonella typhi. Conventionally, typhoid treatment is carried out with antibiotics. The irrationality of antibiotics against S. typhi is reported to trigger bacterial resistance, thus requiring an alternative antibacterial agent against typhoid. The diversity of Indonesian medicinal plants is still promising as a potential source of antibacterial agent, including sendok leaf. This study was aimed to determine antibacterial activity of ethanol extract of kacapiring leaves and its fractions against S. typhi. Subsequent fractionation was carried out using liquid-liquid partition method to obtain n-hexane, ethyl acetate, and etanol-water fractions. Antibacterial test was carried out using disk diffusion method to determine the diameter of inhibitory zone at concentrations of 20%, 25%, 30%, and 40%. The best antibacterial activity was revealed by residue fraction of 30% and 40% with inhibition zone diameter of 8,5 ± 0.051 mm and 8,7 ± 0.081 mm, respectively. Sendok have moderate antibacterial activity against S.typhi.
Formulation of capsule preparations with variations in aerosil concentration on the results of preparation evaluation Arif Wijayanto; Juvita Herdianty
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.132

Abstract

Capsules can be defined as a solid dosage form, where one or more types of drugs and/or other inert ingredients are contained in a shell or small container that can dissolve in water (Ansel 2005). Gelatin is a suitable material for making capsule shells because it is edible and soluble, forms a strong, thin-layered shell and changes from solution to gel form slightly above ambient temperature. Gelatin immediately dissolves in water at body temperature and does not dissolve if the temperature drops below 30°C (Agoes, 2008). Based on the test results, the disintegration time for F1 capsules is 2.12 minutes; F2 is 2.21 minutes; and F3, namely 2.27 minutes. These three formulas meet the requirements, namely not less or equal to 15 minutes. Based on the test results, F1 3.44 seconds, F2 3.76 seconds, F3 3.24 seconds, the flow speed of these three formulas meets the flow speed requirements, namely flow speed ≥ 10 g/second. The flow speed of the three formulas is in the good category, namely 2-10 g/sec which is said to be very good while it is said to be good. The flow speed is good because Aerosil has a very small and fine particle size. Apart from being an absorbent, aerosols are also able to improve flow properties by reducing friction between particles and by averaging test results from angles of repose F1 45°, F2 43° and F3 53°. In the weight uniformity test at F 1,2,3 it does not meet the requirements for factors that influence weight uniformity, namely lack of accuracy, different drug weights due to uneven distribution.
Rationality of Use of Analgetic-Antipyretic Medicines in Northern Region Primary Health Centre of Kediri City Hanie Kusuma Wardani; Krisogonus Ephrino Seran; Elisa Nur Farida
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.133

Abstract

One of the efforts carried out by the national rational drug use program is health services that ensure safety, effectiveness, and affordable costs for people who receive or receive treatment. It is said that the use of drugs is rational if the patient gets treatment according to clinical needs, the dose is as needed, the drug can be used for a sufficient period of time and at affordable costs. This study aims to determine the rationality of the use of analgesic-antipyretic drugs in the Northern Region Primary Health Centre of Kediri City which includes: right indication, right patient, right drug, right dose, and alert for drug side effects. This study is a descriptive study conducted by retrospective observation and data collection by looking at prescriptions and medical record data supported by interviews with pharmacists. Based on the results of the research in the Northern Region Primary Health Centre of Kediri City, it can be found that the use of analgesic-antipyretic drugs in 304 samples was obtained paracetamol 33.88%, paracetamol liquid 18.42%, Alpara 10.20%, ibuprofen 12.17%, acid mefenamic 8.88%, diclofenac sodium 7.24%, piroxicam 4.93%, and aspirin 4.28%. The percentage of rationality of using analgesic-antipyretic drugs in the Northern Region Primary Health Centre of Kediri City, got the results, namely: right indication, right patient, right drug, right dose, and alert for drug side effects by 100%.
Formulation of Wangi Pandan Leaves (Pandanus Amaryllifolius Roxb) to smooth, moisturize and repair the skin Juvita Herdianty; Alfara Derista Felany
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.134

Abstract

Bodyscrub is one of the products that is the result of rapid technological developments today, bodyscrub scrubs are used to maintain the cleanliness and freshness of body skin, bodyscrub products vary greatly starting from price, packaging color, softness of texture and aroma (Nina Hairiyah, Nuryati, and Fitri Nordiyah, 2022).The aim of using a body scrub is to remove dead skin cells, dirt and open pores so that the skin becomes brighter and whiter. Currently, there are many types of body scrubs circulating in society with various benefits ranging from smoothing the skin to whitening the skin (Hairiyah, N., & Nuryati, 2020) Medicinal plants have traditionally been used to treat many diseases and maintain health in Southeast Asia, many plants are described as having traditional medicinal properties. One of the plants that can be used in cosmetics is fragrant pandan leaves (pandanus amaryllifolius roxb) which is a tropical plant from the pandanaceae family. Pandan leaves can also be called pine leaves. because it resembles a pineapple with long, spiral green leaves. narrow and rope-shaped. Pandan leaves contain phytochemical compounds such as steroids, carbohydrates, phenols, flavones, alkaloids, glycosides, amino acids and many vitamins. The appearance and function of the skin is maintained by an important balance between water. This study aims to formulate and evaluate the physical quality results of pandan wangi leaves powder body scrub cream with emulgator concentrations of 15%, 14% and 13% stearic acid, and 1%, 2% and 3% triethanolamine. Experimental research method to determine variations in the concentration of stearic acid and triethanolamine emulsifiers. Observation of the results of evaluating the physical quality of the preparation includes organoleptic tests, homogeneity, pH, stickiness tests, spreadability tests and emulsion type. The result It can be concluded that the fragrant pandan leaf powder body scrub preparation can moisturize the skin, shows a homogeneous scrub with a semi-solid shape, is light green in color and has a typical pandan smell, has a neutral pH of 7.4 and 7.2 on day 7, the pH value is not appropriate The desired number is 6, this is because the preparation is influenced by the number of emulsifiers used. The more stearic acid, the lower the pH because of the large number of acid groups contained in stearic acid, while the more triethanolamine will cause the pH to be high due to the presence of basic groups contained in triethanolamine. with a spreadability of 5.1 cm and 4.83 cm on day 7. This is because the emulsifier concentration is high and the surfactant concentration is low, so the viscosity is very high so the spreadability is low. and the results of adhesion were 88.33 seconds and 49.33 seconds on day 7, adhesion was influenced by the viscosity of the base. Stickiness is closely related to viscosity.
TESTING THE ACTIVITY OF THE N-HEXANE FRACTION OF THE ETHANOL EXTRACT OF BETTER BETTER LEAVES (Momordica Charantia L.) WITH VASELINE CARRIER ON THE HEALING OF CUT WOUNDS IN WHITE RATS (Rattus Norvegicus) Lucky Andriani; Ivan Junius Mesak
Strada Journal of Pharmacy Vol. 2 No. 1 (2020): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v2i1.135

Abstract

Wound are a form of damage to anatomical structure and function. When a wound occurs, the integrity of the epithelial structure of the skin is lost and dysfungtion occours in the skin. Therefore, normalization of integrity is required as soon as possible. Bitter melon leaves have benefits for wound healingand repairing skin granulation tissue. to understand the most optimal concentration level of N-Hexane Fraction of Bitter melon leaf ethanol extract in healing white rat incision wound using vaselin carrier and to understand the healing activity of N-Hexane fraction of Bitter melon leaf extract on white rat incision wound healing. The research conducted was an experimental type with the test animal, namely 18 white male rats. The white rats were grouped into 6 groups, where the standard control was group I, the positive control was group II with (injuring and giving sagestam cream) treatment, the negative control was group III with (injuring and giving it vaseline base) treatment, the last group IV, V, and VI were treated (injuring and giving it n-hexane fraction of bitter melon leaves at concentration levels of 1,5%, 3%, 6% and the base was vaseline).Then induced an incisions wound 2.0 cm deep and 0.2 cm long, but before shaving the rat’s back first and then anesthetizing using lidocaine injection. The observation process is carried out for 2 weeks and data collection is every 2 days. Furthermore, conduct statistical test when the data has been collected. Based on the results of observations and testing of the N-hexane fraction of bitter melon leaf ethanolextract, it has activity in healing cuts in white rats and the most optimal concentration in healing cuts is a concentration of 6%. The N-Hexane fraction of ethanol extract of bitter gourd leaves has activity in healing cuts in white rats and the most optimal concentration in healing cuts is 6%.

Page 5 of 9 | Total Record : 83

 3   4   5   6   7 

Filter by Year

2019 2025


Reset
Filter By Issues
All Issue Vol. 7 No. 2 (2025): October Vol. 7 No. 1 (2025): April Vol. 6 No. 2 (2024): October Vol. 6 No. 1 (2024): April Vol. 5 No. 2 (2023): October Vol. 5 No. 1 (2023): April Vol. 4 No. 2 (2022): October Vol. 4 No. 1 (2022): April Vol. 3 No. 2 (2021): October Vol. 3 No. 1 (2021): April Vol. 2 No. 2 (2020): October Vol. 2 No. 1 (2020): April Vol. 1 No. 2 (2019): October Vol. 1 No. 1 (2019): April More Issue