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INDONESIA
Strada Journal of Pharmacy
Published by Universitas Strada Indonesia
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 83 Documents
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The Effect of Maceration and Soxhletation Extraction Methods on The Flavonoid Content of Anting-anting Leaves Extracts (Acalypha indica L.) Using Uv-Vis Spectrophotometry Dita Intan Karisma; Christina Indriasari
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.101

Abstract

Anting-anting (Acalypha indica L) is an annual plant that reaches 30 to 50 cm in height. This plant is often found on mountain slopes, along roadsides, and meadows. Anting-anting leaves (Acalypha indica L) have anti-inflammatory, antibacterial, and antifungal activities. The high content of flavonoids in the leaves of the earrings is efficacious as an antioxidant. This study aims to determine the effect of maceration and soxhletation extraction methods on the levels of flavonoids in the leaves of the anting-anting. This type of research is an experimental study conducted with two extraction methods using 96% ethanol. Qualitative analysis was carried out by color reaction test while quantitative analysis was carried out using a UV-Vis spectrophotometer with the calorimetry method. The standard solution used was quercetin to measure the levels of flavonoids. The results showed that the average level of flavonoids in soxhletation extraction was 5.2266%w/b and in maceration extraction was 5.0084%w/b. The data were tested using the Independent Sample T Test showing a significance value of 0.097 (> 0.05), meaning that there was no significant effect between the maceration and soxhletation extraction methods.
Factors Influencing Satisfaction With Pharmacy Services In Out Patients At DKT Madiun Hospital Hanik Mariana Dewi; Ririn Ernawati; Fidi Setyawan
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.103

Abstract

Patient satisfaction is one of the components used to assess whether a service system is good or bad. The aim of this research is to determine the factors of attitude and waiting time with satisfaction with pharmaceutical services. This type of research is correlation analytic with a cross-sectional approach. The sampling technique was purposive sampling with a sample of 216 patients. Data collection uses questionnaires (attitude and satisfaction) and watches (waiting time). The research results showed that the average waiting time was around 17.49 minutes, as many as 117 (81.9%) respondents from pharmacy staff behaved well and 185 respondents (85.65%) were satisfied with pharmacy services. The Spearman rank statistical test shows that there is a relationship between the officer's attitude and waiting time and satisfaction with pharmaceutical services (p value 0.04 and 0.000 < α = 0.05). Attitudes and waiting times for pharmaceutical services are important factors in improving the quality of pharmaceutical services.
Description Of The Usage Of Antiretroviral Medicine With Atc/Ddd Method In The Primary Health Care Centers Of Kediri 2021 Dandi Fathor Rozy Pradana Saputra; Chinthia Devientasari
Strada Journal of Pharmacy Vol. 6 No. 1 (2024): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i1.109

Abstract

AIDS (Acquired Immune Deficiency Syndrome) is a collection of symptoms and infections caused by damage to the human immune system, HIV (Human Immunodeficiency Virus ), a virus that can weaken human immunity. PLWHA patients must undergo antiretroviral virus (ARV) drug therapy, one of the drug use analysis classification systems is using the ATC/DDD system which is a means of researching drug use in an effort to improve the quality of drug use, one of these components is the presentation and comparison of drug consumption levels. international. The aim of this research is to determine the use of antiretroviral drug consumption in primary health care center in the Kediri City area for the 2021 period using the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) method. The design of this research is quantitative descriptive, namely describing a particular event systematically and accurately and the treatment of this research is the process of collecting data and evaluating the use of antiretroviral drugs as well as verifying Primary health care center data by interviewing primary health care center pharmacists in the Kediri city area in 2021. Consumption of antiretroviral drugs (ARVs). ) is highest in the Campurejo primary health care center, namely Lamivudine (3TC) as much as 31.71%, Balowerti in primary health care center with Zidovudine (AZT) as much as 29.02% and Pesantren 1 primary health care center with the drug Nevirapine (NVP) as much as 32.62%, while the use of ARV drugs is low. At the Campurejo primary health care center, it was 0.0002% of the drug Dolutegravir (DTG), and at the Balowerti primary health care center, it was 0.0012% of the drug Dolutegravir (DTG), then at Pesantren 1 primary health care center , it was 0.0015% of the drug Dolutegravir (DTG). The incidence of HIV is still high in Indonesia, especially in the city of Kediri.
Testing The Effectiveness Of Burns Healing Of Gel Preparations Jatropagar ( Jatropha Curcas L) Leaf Extract On Male White Rats ( Rattus Norvegicus) Angelina Tamo Inya; Ivan Junius Mesak
Strada Journal of Pharmacy Vol. 6 No. 1 (2024): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i1.110

Abstract

Indonesia has a variety of traditional medicinal plants for treating burns. One of them is Jatropha leaves which contain active substances such as saponins, tannins, alkaloids and flavonoids which have antibacterial, antioxidant, anticancer and anti-inflammatory properties. The aim of this research was to determine the effectiveness of Jatropha leaf preparations with extract concentrations of 10%, 15%, 20% on healing burns. This research stage includes plant determination, simplicia making, extract making, phytochemical screening testing, physical quality testing of gel preparations and animal testing. The research was experimental by comparing the effectiveness of healing burns in grouped mice and Jatropha leaf extract gel preparations and the most effective formula for healing burn wounds was Jatropha leaf extract gel preparations at concentrations of 10%, 15%, 20%. Statistical test results showed that there was a difference in the duration of healing of burn wounds in male white rats between Jatropha curcas (Jatropha curcas L) leaf gel preparations with concentrations of 10%, 15%, 20%, bioplaceton gel and gel base.
Rationality of Prescribing Diabetes Mellitus Drugs Using Beers Criteria for Geriatric Patients in Outpatient Installations dr. Iskak Hospital Kuni Rofi'aty; Hanie Kusuma Wardani
Strada Journal of Pharmacy Vol. 6 No. 1 (2024): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i1.117

Abstract

Diabetes mellitus (DM) is se group of metabolic disorders with symptom hyperglycemia Which happen caused because abnormality secretion insulin and insulin action or both . Diabetes mellitus (DM) is a global problem in which 20% of sufferers are geriatrics. Treatment of DM in geriatrics has the potential to occur irrationally due to the complexity of health problems in geriatrics. Irrational prescribing has a negative impact on health care facilities, patients, and society. One method of assessing rational prescribing is the Beers criteria, developed by the American Geriatrics Society Beers Criteria 2 019. The purpose of this study was to determine the rationality of prescribing DM drugs using the Beers criteria for geriatric patients at the outpatient installation at RSUD dr. Iskak Tulungagung. This research is a descriptive observational study with a cross sectional design. Retrospective data collection on 275 medical record documents of geriatric patients with a diagnosis of DM at the outpatient installation of RSUD dr. Iskak – Tulungagung in the 2021 period. Samples were analyzed using the American Geriatrics Society Beers Criteria 2019 guidelines . The results of the study DM drugs in the Sulfonylurea class were most widely used (13.1%) and 41,3 % identified potentially inappropriate medications (PIMs). The use of potentially inappropriate drugs is 7,32 %, the use of drugs that interact with disease is 3,8%, the drugs that must be used with caution, 6,4%, the drugs that have the potential to interact clinically 0,3%, and the use of drugs that must be avoided or reduced dose related to renal function 0,3%.
Development of a Wireless Communication Enabled Device for Monitoring Heart Rate and Body Temperature for Independent Use La Febry Andira Rose Cynthia; Alvin Hetriawan; Fatkhur Rokhman; Muhammad Faris Pradana; Lailis Syafa’ah
Strada Journal of Pharmacy Vol. 6 No. 1 (2024): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i1.118

Abstract

Human health conditions can be seen from their heart rate and body temperature. Research aims to make it easier for health workers and humans in general to know their heart rate and body temperature. Therefore, a portable heart rate monitoring device was designed that uses an IoT system. The portable design aims to make the tool practical, and the use of IoT makes it easier for health workers to see patient conditions remotely. The MAX30100 sensor is used to determine heart rate while the DS18B20 sensor is used to determine body temperature which is connected to the microcontroller. It is hoped that this research will make it easier for health workers and humans to receive immediate treatment during emergencies.
Evaluation Of Physical Properties Of Liquid Soap Preparations From Virgin Coconut Oil (VCO) And Coconut Oil (CO) Natalino Nunu Pote
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.119

Abstract

Soap is a compound of sodium or potassium and fatty acids from animal oils and vegetable fats which is obtained by the oil hydrolysis process which is then followed by a saponification process under alkaline conditions. Making liquid soap products uses the oil phase, namely virgin coconut oil (VCO) and coconut oil (CO).used as raw material for making surfactants. Surfactants are able to reduce surface tension and interfacial tension by producing foam. The characteristic that influences the quality of liquid soap foam is the fatty acid content. The fatty acid content can affect the physical properties of liquid soap products. The different types of coconut oil used cause the fatty acids contained to be different.Physical properties testing is carried out to find outWhich liquid soap formulation from (VCO) and (CO) formula has the best physical properties.The procedure for making this liquid soap uses the Hot Process method. This method is used because it adapts to the heat- resistant characteristics of coconut oil. The results of the research showed that liquid soap preparations from (VCO) and (CO) were evaluated for their physical properties in terms of organoleptic and stability parameters such as foam height test, pH test, homogeneity test, viscosity test and specific gravity test, which obtained a significant value of <0.05. meaning they both have good physical characteristics. As well as respondents' acceptance of the physical properties of liquid soap preparations from (VCO) and (CO) where the results show that respondents have the same satisfaction regarding the quality of liquid soap.
Analysis of Family Support and Levels of Depression HIV/AIDS Patients in Adherence of Antiretroviral Medication in Kediri City Hanie Kusuma Wardan
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.120

Abstract

Antiretroviral (ARV) medication adherence is important because ARV can improve quality of live in HIV/AIDS’ patients. Adherence to ARV medication influenced many factors, including family support and levels of depression experienced by patients of HIV/AIDS. The purpose of this research is to analyze the effect of family support and levels of depression patients HIV/AIDS against the ARV medication adherence in Kediri. Research’s design is quantitative research using the approach of cross sectional. The sampling technique used is proportional sampling with cluster random samples as much as 133 respondents who get ARV therapy in Gambiran Hospital, “Pesantren 1” Primary Health Centre, and Seroja Clinic. Data analysis techniques using logistic regression test. The results show that 133 of the respondents, 98 respondents (73.7%) get family support and adherence taking ARV medication, and 99 respondents (74.4%) are not depressed and adherence taking ARV medication. Adherence in this research is referred to take ARV by dosage and by time exactly in schedule. The results of the analysis using logistic regression test shows the value significance of 0.000 < (α = 0.05), meaning that H0 is rejected and the H1 is accepted, this means that there is a relationship of family support and levels of depression HIV/AIDS’ patients against the ARV medication adherence. Family Support and levels of depression HIV/AIDS’ patients affect the ARV medication adherence 80.2%. Conclusion, to get adherence in ARV treatment, HIV’s patient needs family support and get not in depression condition.
Variations in Aerosil concentration in Chlorpeniramin Maleat (CTM) capsule preparations on test results Melinda Putri
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.121

Abstract

Capsules are solid preparations consisting of a drug in a hard or soft shell that can dissolve. (Fatmawaty, et al. 2012). Hard capsules are usually made from gelatin which consists of the capsule shell, the body and the capsule cap. The two parts of the capsule cover will cover each other when brought together and the cover will cover the body of the capsule (Ansel, 2005). Chlorpeniramin Maleat CTM) is used as an antihistamine. Antihistaminics are drugs that oppose the action of histamine on H-1 histamine receptors so they are useful in suppressing allergies caused by the appearance of symptoms due to histamine (Ansel, 1989). Antihistamines work by occupying the place in cells normally occupied by histamine, thereby eliminating histamine's ability to cause allergic reactions (Harkness, 1989). Adsorbents are substances that trap other components such as water. Aerosil is an adsorbent that is widely used in capsule preparations. Apart from having a large water absorption capability and capacity of around 50%, if dried, Aerosil will not reduce the existing water content (Lachman, 1989). The active ingredient used is CTM, where this material is hygroscopic, meaning it is able to absorb water molecules from its environment, so adsorbents are added to prevent moisture from the preparation during storage. Based on the description above, this formulation was made by varying the aerosil concentration, namely 5% (F1); 7% (F2); and 9% (F3) which is intended to observe the ability of the adsorbent as seen from hygroscopic testing of the preparation during storage. The results of this research is disintegration time on our formulations resulted in formulation 1 starting to disintegrate within 01:03 until it was completely dissolved, taking 12:02. formulation 2 started to break down within 01:40 and until everything dissolved with a duration of 12:02. The 3rd formulation started to break down within 02:05 with the total duration until it was completely dissolved was 12:58. These three formulations are in accordance with the FI standard, namely less than 30 minutes.
EFFECTIVENESS OF PHARMACIST COUNSELING ON ADHERENCE TO ANTIHYPERTENSIVE THERAPY OF HYPERTENSION PATIENTS IN PUSKESMAS NGLETIH Indah Yuli Antika
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.122

Abstract

Hypertension or high blood pressure is an increase in systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg in two measurements with an interval of five minutes in a state of rest/quiet. The use of antihypertensive drugs must always be monitored because long-term use of drugs will affect adherence to taking medication and cause further complications or disease severity. Counseling provided by pharmacists is one of the efforts to educate and monitor patient treatment to increase patient compliance in undergoing treatment.

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