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Juvita Herdianty
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INDONESIA
Strada Journal of Pharmacy
Published by Universitas Strada Indonesia
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 83 Documents
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Gambaran Tingkat penggunaan Obat Generik dan Obat Paten di Depo Rawat Jalan Instalasi Farmasi RSUD Arifin Nu’mang Kabupaten Sidenreng Rappang Fitriana Bunyanis; Nur Astuti Wulandari
Strada Journal of Pharmacy Vol. 3 No. 1 (2021): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v3i1.80

Abstract

This study aims to determine the level of use of generic drugs and patent drugs in outpatient depots of the pharmacy installation at Arifin Nu'mang Hospital, Sidenreng Rappang Regency with descriptive research methods. Descriptive method is a method that serves to describe or provide an overview of the object under study through the sample and population. From the results of the research that has been done, the percentage of generic drugs was obtained as much as 75.42%, while the percentage of patent drugs was 24.38%. The percentage of generic drugs has not met the stipulated provisions. This can be caused by several things, one of which is the patient asking the doctor to write a patent drug prescription.
Influence of “Gema Cermat” Education to Increased Hb Levels for Pregnant Women in Kediri – East Java Hanie Kusuma Wardani; Hanni Prihastuti Puspitasari; Yuni Priyandani
Strada Journal of Pharmacy Vol. 5 No. 1 (2023): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i1.86

Abstract

The prevalence of iron deficiency anemia in pregnant women globally reaches 52% in developing countries, including Indonesia. The impact of anemia on pregnant women is premature birth, LBW, bleeding, and even the mother and baby's death. To overcome this, the Indonesian government has ironic-folic acid (IFA) supplementation program for pregnant women with at least 90 tablets during their pregnancy. This program has walked since the 1990s, but anemia in Indonesia is still high (48.9%). Because of these issues, the Ministry of Health gave education for increased use of IFA in pregnant women, namely "Gema Cermat". The purpose of this study is to know the effect of "Gema Cermat" education on increasing Hb levels of pregnant women. This study is a quasi-experimental design, one-group pre-test post-test only, carried out on 41 pregnant women in 3 Primary Health Care Centers in Kediri City. This research measures Hb levels before and after "Gema Cermat" education. Research results in 78% of pregnant women at 20-35 years old, domiciled in Kediri City (98%), level of education is high school (51%). History of multiparous pregnancy (76%), no experience of lack of chronic energy (93%), and increasing Hb level of 1.3g/dl. The Wilcoxon Signed Rank Test analysis results in this study conclude that "Gema Cermat" education is influential in enhancing Hb-level pregnant women.
Formulation Of Mephenamic Acid Granules With Pvp And Avicel Mixture On The Physical Of Granules Juvita Herdianty; Arif Wijayanto; Atary Anggita
Strada Journal of Pharmacy Vol. 5 No. 1 (2023): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i1.87

Abstract

Mefenamic acid is a drug that is often used to relieve pain. Mefenamic acid is a drug used as an analgesic, antipyretic, and non-steroidal anti-inflammatory drug (NSAID). In the BCS (Biopharmaceutical Classification System) it is included in the class II category, namely its low solubility with high permeability. To overcome this, it is necessary to make efforts to increase solubility to obtain good bioavailability. This study aims to formulate granules using a mixture of Polyvinyl Pyrrolidone (PVP) and Avicel for the physical properties of the granules in three formulations. Preparation of granules using the wet garnulation method by making three formulations with varying concentrations of PVP, namely 1%, 2% and 3%. The results of the evaluation of the physical properties of mefenamic acid granules showed that the flow properties of the three formulas met the requirements, namely > 10 grams/second. The water content test showed that the three formulas met the requirements with a range of 2-5%, while the angle of repose test of the three formulas was only formula 1 which met the requirements, namely less than <30o.
Effect Test of Analgesics (Paracetamol, Ibuprofen, and Antalgin) in Local Strain Male Mice with Acetic Acid Induction Using the Writhing Test Method Chinthia Devientasaria; Luluk Aniqoh Meliana Putri
Strada Journal of Pharmacy Vol. 5 No. 1 (2023): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i1.88

Abstract

Analgesic or pain blocking drugs are compounds that reduce or eliminate pain without causing loss of consciousness. NSAID (non-steroidal anti-inflammatory drugs) are heterogeneous compounds due to the different chemical structures of NSAID compounds, which are used to reduce mild to moderate pain, such as paracetamol, mefenamic acid, and ibuprofen. Paracetamol is used to reduce body heat caused by infection or something else. In addition, this drug also relieves pain at a mild to moderate level, this analgesic works directly on the body’s heat regulating center in the hypothalamus. The method use is writing test with acetic acid induction. The result of this study indicates that testing the effectiveness of the paracetamol, ibuprofen, and antalgin analgesic drugs in mice study showed that the analgesic power of antalgin was the best compared to paracetamol and ibuprofen.
Antibacterial FormulationEmulgel Preparation Containing 3% Citronella Oil (Cymbopogon Nardus L) With Carbomer 0.5%, 1%, 1.5% Devita Riafinola Andaririt
Strada Journal of Pharmacy Vol. 5 No. 1 (2023): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i1.93

Abstract

Acne is a bacterial infection that can diminish a person's confidence. Acne is caused by the microorganisms Propionibacterium acnes. Citronella oil has citronellal, citronellol, geraniol compounds that contain a very strong antimicrobial activity. Therefore, emulsion-based topical preparations are made with carbomer bases that are suitable for use. This study sought to determine the effect of 0.5%, 1%, and 1.5% carbomer bases with 3% citronella oil extract on the chemical physics properties of emulsion preparations. (Organoleptic, pH, viscosity and dispersion, stability and Freeze-Thaw test). This investigation employed an experimental method to compare three formulas with varying levels of carbomer in an emulsion preparation test for citronella oil extract. The researcher then analysed the chemical substance's physical characteristics. Based on the evaluation results, it was determined that all formulations had identical organoleptic properties, including a silky texture, citronella oil aroma, and a white hue. According to the results of One-Way ANOVA, viscosity, pH, dispersion, stability, and the Freeze-Thaw test, there were no significant variations in the formula.
An overview of the success of the “PADAMU DHIVA” program on adherence to consuming ARVs for HIV-AIDS patients at the Balowerti Primary Health Care Center Twoti Dika Parmanasari; Hanie Kusuma Wardani
Strada Journal of Pharmacy Vol. 5 No. 1 (2023): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i1.94

Abstract

Adherence to anti-retroviral (ARV) treatment in HIV/AIDS patients is essential to suppress the growth of the virus optimally and improve the patient's quality of life. HIV/AIDS patients can only miss 1-2 doses within one month of consuming ARVs, meaning their adherence to ARVs must be more than 95%. A medication assistance program for HIV/AIDS patients on ARV (Padamu Dhiva) was created to achieve and maintain this high adherence. This study aims to provide an overview of the successful implementation of the "Padamu Dhiva" Program on the commitment to consuming ARVs in HIV/AIDS patients. This research is a quantitative descriptive study conducted on 92 HIV/AIDS patients at the Balowerti Primary Health Care Center in implementing the "Padamu Dhiva" Program, start from January to December 2022. Data obtained on increasing patient compliance from groups 2 and 3 adherence values to compliance value 1 was 90%. Pharmacists are also greatly facilitated by the "Padamu Dhiva" Program, the amount of remaining medication the patient has per day can be known directly, and a warning appears for the pharmacist when it is time to give a reminder to the patient. The system already connected to the Whatsapp application also makes it easier for pharmacists to contact patients individually. With this program, the incidence of loss to follow-up shows a decrease of 33.3%. The "Padamu Dhiva" program increases adherence to ARV in HIV/AIDS patients at the Balowerti Primary Health Care Center.
Antibacterial Test Of Telang Flower Extract (Clitorea Ternatea L.) Against Pseudomonas Aeruginosa Luluk Aniqoh Meliana Putri; Chinthia Devientasaria
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.96

Abstract

The butterfly pea flower is a shrub that can grow and live for years (perennial), can reach a height of 5 meters, has fine hair, and is woody at the base, the flower color is bright blue with a yellowish white color in the middle. Butterfly pea flower (Clitoria ternatea L.) is a plant that has long been used in medicine and has been proven to contain alkaloid and flavonoid secondary metabolite compounds which have antibacterial potential. Antibacterials are substances that can interfere with the growth or even kill bacteria by interfering with the metabolism of harmful microbes. The aim of this research was to determine the inhibitory power of telang flower simplicia extract (Clitoria ternatea L.) on the growth of Pseudomonas aeruginosa bacteria. This research aims to test the activity of butterfly pea flowers, namely by maceration using 70% ethanol solvent. For antibacterial testing using the disk diffusion method. Extracts are made in various concentrations of 10%, 20%, 30%. The positive control used was Chloramphenicol. The results of this research were that the average zone of inhibition of butterfly pea flower extract against Pseudomonas aeruginosa bacteria was 1.48 mm at 10% concentration, 2.41 mm at 20% concentration, and 5.70 mm at 30% concentration. These results show that butterfly pea flower extract has antibacterial activity against Pseudomonas aeruginosa bacteria, although the resulting inhibitory power is not strong. At a concentration of 30% butterfly pea flower extract, it has the greatest inhibitory effect on the growth of Pseudomonas aeruginosa bacteria than concentrations of 10% and 20%.
The Effectivity Of Juwet (Syzygium Cumini) Leaf Ethanolic Extract In Rabbit’s Wound Healing Miranda Susanti Putri
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.97

Abstract

Medical plant which has fewer side effects than chemical drugs, is used by people as an alternative to treat wound. Juwet as a medicinal plant has the potential to be developed as a wound healer. The purpose of this study was to determine the ability or activity of juwet leaf extract (Syzygium cumini) in wound healing. The test was carried out using New Zealand rabbits by making wounds on the rabbit's back which were then divided into 5 treatment groups. The treatment group consisted of Group I given aquadestilata, Group II given povidone iodine, Group III given 25% juwet leaf extract, Group IV given 50% juwet leaf extract, and Group V given 75% juwet leaf extract. The results showed that juwet leaf extract (Syzygium cumini) affected wound healing. Average wound diameter consecutively 6,69±1,34, 5,79±2,19, and 4,50±1,70 on day-7. 0,70±0,99, 0,46±0,65, and 0,00±0,00 on the day-10. Based on the results of the research conducted, it can be concluded that juwet leaf extract (Syzygium cumini) has a wound-healing effect on rabbits and the best concentration of juwet leaf extract (Syzygium cumini) for wound-healing activity is 75%.
Activity Testing Of Katuk Leaf Ethyl Acetate Fraction Gel Preparation (Sauropus Androgynus (L.) Merr.) On Healing Wistar Strain White Rat Burns Mintarti; Juvita Herdianty
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.98

Abstract

Burns are a condition of loss or damage to skin tissue due to contact between the skin and a heat source. The ethyl acetate fraction of katuk leaves (Sauropus Androgynus (L.) Merr.) is known to be able to help accelerate the healing process of burns because it contains flavonoids, alkaloids, tannins and saponins. The purpose of this study was to analyze the effect of giving the ethyl acetate fraction of katuk leaves and to find out the best concentration of the fraction in healing burns. This study was a laboratory experimental study using the Post Test Control Only Group Design approach using 25 male white rats divided into 5 groups (each group consisted of 5 rats). The treatment groups were K+ (bioplacenton), K- (base), the ethyl acetate fraction of katuk leaves which consisted of several concentrations, namely F I (5%), F II (10%), F III (20%). The parameters observed were a decrease in the diameter of the burn wound and healing of the skin of the rats. Based on the results of observations of healing of burns, statistically showed a significant difference between groups with a p value <0.05. The best concentration in healing burns on the rat's back was a concentration of 20% with a healing percentage of 83.11%, followed by a concentration of 10% (66.71%), a concentration of 5% (56.00%). The healing activity of burns in the positive control with a healing percentage of 82.35%. So the best burn healing activity was in the ethyl acetate fraction of katuk leaves with a concentration of 20% with a healing percentage of 83.11%.
Testing the Anti-Bacterial Activity of Star Gooseberry Leaves (Souropus Androgynus L) Using the Disc Diffusion Method Using the n-Hexane Fraction Against Propionic Bacterium Acnes Devita Riafinola Andaririt; Ardi Broto
Strada Journal of Pharmacy Vol. 5 No. 2 (2023): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v5i2.100

Abstract

Acne vulgaris or acne, is a common inflammatory condition in the polysebaceous unit that occurs in teenagers and young adults and is characterized by comedones, papules, pustules, and nodules. One of the factors that causes acne is the Propionic bacterium acnes bacteria. One type of plant with antibacterial properties for acne is the Star Gooseberry Leaf plant (Souropus Androgynus L), which contains alkaloids, saponins, tannins, and flavonoids that act as antibacterials. Susanti (2012). This research aimed to obtain data on the antibacterial activity of the compound components contained in the n-hexane fraction of Star Gooseberry Leaves (Souropus Androgynus L) against the Propionic bacterium acnes bacteria, which can be seen from the inhibition zone. The method used was disc diffusion with three groups of control, namely (K(S), K(+), and K(-)). The test bacteria Propionic bacterium acnes, where the Control Sample consists of 4 test concentrations, namely 30 mg, 60 mg, 120 mg, and 240 mg. The positive control used two µg/disc Clindamycin, while the negative control was 2% DMSO. The results of the disc diffusion test of the ethanol fraction of Star Gooseberry Leaves (Souropus Androgynus L) using the disc diffusion method with concentrations of 30 mg/ml and 60 mg/ml did not provide an inhibition zone, the concentration of 120 mg/ml was 11.1 ± 0.10 mm, the concentration was 240 mg/ml was 14.63 ± 0.25 mm. The negative control DMSO 2% did not provide an inhibitory zone diameter, whereas the positive control Clindamycin 2 µg/disk provided an inhibition zone of 25.47 ± 0.70 mm.

Page 3 of 9 | Total Record : 83

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